JP2019524782A5 - - Google Patents
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- Publication number
- JP2019524782A5 JP2019524782A5 JP2019505490A JP2019505490A JP2019524782A5 JP 2019524782 A5 JP2019524782 A5 JP 2019524782A5 JP 2019505490 A JP2019505490 A JP 2019505490A JP 2019505490 A JP2019505490 A JP 2019505490A JP 2019524782 A5 JP2019524782 A5 JP 2019524782A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- mercaptoethylisophthalamide
- nbmi
- bis
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims 8
- 229960005489 paracetamol Drugs 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 6
- 231100000419 toxicity Toxicity 0.000 claims 6
- 230000001988 toxicity Effects 0.000 claims 6
- 230000002265 prevention Effects 0.000 claims 5
- 208000007788 Acute Liver Failure Diseases 0.000 claims 3
- 206010000804 Acute hepatic failure Diseases 0.000 claims 3
- 231100000836 acute liver failure Toxicity 0.000 claims 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims 3
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1613535.2 | 2016-08-05 | ||
| GB201613535 | 2016-08-05 | ||
| PCT/GB2017/052306 WO2018025049A1 (en) | 2016-08-05 | 2017-08-04 | New use of n,n-bis-2-mercaptoethyl isophthalamide |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019524782A JP2019524782A (ja) | 2019-09-05 |
| JP2019524782A5 true JP2019524782A5 (https=) | 2020-09-10 |
| JP6926192B2 JP6926192B2 (ja) | 2021-08-25 |
Family
ID=60202272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019505490A Active JP6926192B2 (ja) | 2016-08-05 | 2017-08-04 | Ｎ，ｎ−ビス−２−メルカプトエチルイソフタルアミドの新規用途 |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US20190240173A1 (https=) |
| EP (2) | EP4029497A1 (https=) |
| JP (1) | JP6926192B2 (https=) |
| KR (1) | KR102538388B1 (https=) |
| CN (1) | CN109562179A (https=) |
| AU (1) | AU2017305661B2 (https=) |
| BR (1) | BR112019002130A2 (https=) |
| CL (1) | CL2019000229A1 (https=) |
| CY (1) | CY1125039T1 (https=) |
| DK (1) | DK3493849T3 (https=) |
| EA (1) | EA201990443A1 (https=) |
| ES (1) | ES2907838T3 (https=) |
| HR (1) | HRP20220252T1 (https=) |
| HU (1) | HUE057782T2 (https=) |
| IL (1) | IL264538B2 (https=) |
| LT (1) | LT3493849T (https=) |
| MA (1) | MA45855B1 (https=) |
| MD (1) | MD3493849T2 (https=) |
| MX (1) | MX387853B (https=) |
| MY (1) | MY199733A (https=) |
| PH (1) | PH12019500237A1 (https=) |
| PL (1) | PL3493849T3 (https=) |
| PT (1) | PT3493849T (https=) |
| RS (1) | RS62924B1 (https=) |
| SG (1) | SG11201900565RA (https=) |
| SI (1) | SI3493849T1 (https=) |
| SM (1) | SMT202200109T1 (https=) |
| UA (1) | UA125394C2 (https=) |
| WO (1) | WO2018025049A1 (https=) |
| ZA (1) | ZA201900594B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202005057D0 (en) | 2020-04-06 | 2020-05-20 | Emeramed Ltd | New Use |
| WO2026037909A1 (en) * | 2024-08-16 | 2026-02-19 | Emeramed Limited | N,n-bis-2-mercaptoethyl isophthalamide for use in the treatment of pain |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6586600B2 (en) | 2000-12-06 | 2003-07-01 | University Of Kentucky Research Foundation | Multidentate sulfur-containing ligands |
| US8950583B2 (en) * | 2008-12-06 | 2015-02-10 | Ermes Medical Company Limited | Method to remove heavy metals from a mammal |
| US20120122787A1 (en) | 2009-07-10 | 2012-05-17 | Rong Li | Methods for treating polycystic kidney disease (pkd) or other cyst forming diseases |
| JP2013505963A (ja) | 2009-09-28 | 2013-02-21 | ユニヴァーシティ オブ ケンタッキー リサーチ ファウンデイション | 汚染された環境から元素を除去するチオール含有化合物およびその使用方法 |
| US8575218B2 (en) | 2009-09-28 | 2013-11-05 | The University Of Kentucky Research Foundation | Thiol-containing compounds for the removal of elements from tissues and formulations therefor |
| US20110237776A1 (en) | 2010-03-25 | 2011-09-29 | Haley Boyd E | Aromatic compounds with sulfur containing ligands |
| US8426368B2 (en) | 2010-03-25 | 2013-04-23 | The University Of Kentucky Research Foundation | Method of ameliorating oxidative stress and supplementing the diet |
-
2017
- 2017-08-04 WO PCT/GB2017/052306 patent/WO2018025049A1/en not_active Ceased
- 2017-08-04 SG SG11201900565RA patent/SG11201900565RA/en unknown
- 2017-08-04 CN CN201780046065.1A patent/CN109562179A/zh active Pending
- 2017-08-04 DK DK17793720.8T patent/DK3493849T3/da active
- 2017-08-04 EP EP21211493.8A patent/EP4029497A1/en not_active Withdrawn
- 2017-08-04 EP EP17793720.8A patent/EP3493849B1/en active Active
- 2017-08-04 SI SI201731094T patent/SI3493849T1/sl unknown
- 2017-08-04 MX MX2019000978A patent/MX387853B/es unknown
- 2017-08-04 HU HUE17793720A patent/HUE057782T2/hu unknown
- 2017-08-04 EA EA201990443A patent/EA201990443A1/ru unknown
- 2017-08-04 MD MDE20190671T patent/MD3493849T2/ro unknown
- 2017-08-04 US US16/318,842 patent/US20190240173A1/en not_active Abandoned
- 2017-08-04 PT PT177937208T patent/PT3493849T/pt unknown
- 2017-08-04 JP JP2019505490A patent/JP6926192B2/ja active Active
- 2017-08-04 RS RS20220147A patent/RS62924B1/sr unknown
- 2017-08-04 LT LTEPPCT/GB2017/052306T patent/LT3493849T/lt unknown
- 2017-08-04 PL PL17793720T patent/PL3493849T3/pl unknown
- 2017-08-04 MY MYPI2019000127A patent/MY199733A/en unknown
- 2017-08-04 SM SM20220109T patent/SMT202200109T1/it unknown
- 2017-08-04 MA MA45855A patent/MA45855B1/fr unknown
- 2017-08-04 HR HRP20220252TT patent/HRP20220252T1/hr unknown
- 2017-08-04 KR KR1020197003227A patent/KR102538388B1/ko active Active
- 2017-08-04 BR BR112019002130-2A patent/BR112019002130A2/pt not_active Application Discontinuation
- 2017-08-04 ES ES17793720T patent/ES2907838T3/es active Active
- 2017-08-04 AU AU2017305661A patent/AU2017305661B2/en active Active
- 2017-08-04 UA UAA201902172A patent/UA125394C2/uk unknown
-
2019
- 2019-01-28 ZA ZA2019/00594A patent/ZA201900594B/en unknown
- 2019-01-29 CL CL2019000229A patent/CL2019000229A1/es unknown
- 2019-01-29 IL IL264538A patent/IL264538B2/en unknown
- 2019-02-01 PH PH12019500237A patent/PH12019500237A1/en unknown
-
2022
- 2022-03-01 CY CY20221100175T patent/CY1125039T1/el unknown
-
2024
- 2024-12-06 US US18/972,315 patent/US20250325503A1/en active Pending
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