JP2019524768A5 - - Google Patents
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- JP2019524768A5 JP2019524768A5 JP2019505179A JP2019505179A JP2019524768A5 JP 2019524768 A5 JP2019524768 A5 JP 2019524768A5 JP 2019505179 A JP2019505179 A JP 2019505179A JP 2019505179 A JP2019505179 A JP 2019505179A JP 2019524768 A5 JP2019524768 A5 JP 2019524768A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- l1cam
- cancer
- administered
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022092913A JP2022118058A (ja) | 2016-08-02 | 2022-06-08 | 転移性がんの処置および転移性疾患のためのモデルシステム |
| JP2025030120A JP2025078664A (ja) | 2016-08-02 | 2025-02-27 | 転移性がんの処置および転移性疾患のためのモデルシステム |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662370108P | 2016-08-02 | 2016-08-02 | |
| US62/370,108 | 2016-08-02 | ||
| PCT/US2017/045145 WO2018026947A1 (en) | 2016-08-02 | 2017-08-02 | Treating metastatic cancer and model systems for metastatic disease |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022092913A Division JP2022118058A (ja) | 2016-08-02 | 2022-06-08 | 転移性がんの処置および転移性疾患のためのモデルシステム |
| JP2025030120A Division JP2025078664A (ja) | 2016-08-02 | 2025-02-27 | 転移性がんの処置および転移性疾患のためのモデルシステム |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019524768A JP2019524768A (ja) | 2019-09-05 |
| JP2019524768A5 true JP2019524768A5 (https=) | 2020-09-10 |
| JP7751372B2 JP7751372B2 (ja) | 2025-10-08 |
Family
ID=61073928
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019505179A Active JP7751372B2 (ja) | 2016-08-02 | 2017-08-02 | 転移性がんの処置および転移性疾患のためのモデルシステム |
| JP2022092913A Pending JP2022118058A (ja) | 2016-08-02 | 2022-06-08 | 転移性がんの処置および転移性疾患のためのモデルシステム |
| JP2025030120A Pending JP2025078664A (ja) | 2016-08-02 | 2025-02-27 | 転移性がんの処置および転移性疾患のためのモデルシステム |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022092913A Pending JP2022118058A (ja) | 2016-08-02 | 2022-06-08 | 転移性がんの処置および転移性疾患のためのモデルシステム |
| JP2025030120A Pending JP2025078664A (ja) | 2016-08-02 | 2025-02-27 | 転移性がんの処置および転移性疾患のためのモデルシステム |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US11464874B2 (https=) |
| EP (2) | EP4623998A3 (https=) |
| JP (3) | JP7751372B2 (https=) |
| KR (2) | KR20190036553A (https=) |
| AU (2) | AU2017306426B2 (https=) |
| CA (1) | CA3029653A1 (https=) |
| ES (1) | ES3037528T3 (https=) |
| IL (1) | IL264024A (https=) |
| WO (1) | WO2018026947A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| CN106661548B (zh) | 2014-05-28 | 2020-12-11 | 儿童医院医疗中心 | 用于经由定向分化将前体细胞转化为胃组织的方法和系统 |
| JP6804438B2 (ja) | 2014-10-17 | 2020-12-23 | チルドレンズ ホスピタル メディカル センター | 多能性幹細胞を使用するヒト小腸のｉｎ ｖｉｖｏモデル、並びにそれを作製、及び使用する方法 |
| ES2929758T3 (es) | 2016-05-05 | 2022-12-01 | Childrens Hospital Med Ct | Métodos para la fabricación in vitro de tejido del fondo gástrico y composiciones relacionadas con el mismo |
| KR102729404B1 (ko) | 2016-11-04 | 2024-11-14 | 칠드런즈 호스피탈 메디칼 센터 | 간 유사 장기 조성물 및 이를 제조 및 사용하는 방법 |
| JP7068305B2 (ja) | 2016-12-05 | 2022-05-16 | チルドレンズ ホスピタル メディカル センター | 結腸オルガノイドならびにその作製方法および使用方法 |
| US12281334B2 (en) | 2017-04-14 | 2025-04-22 | Children's Hospital Medical Center | Multi donor stem cell compositions and methods of making same |
| EP3694603B1 (en) | 2017-10-10 | 2026-04-08 | Children's Hospital Medical Center | Esophageal tissue and/or organoid compositions and methods of making same |
| US12379372B2 (en) | 2017-12-21 | 2025-08-05 | Children's Hospital Medical Center | Digitalized human organoids and methods of using same |
| WO2020003210A1 (en) | 2018-06-29 | 2020-01-02 | Kangwon National University University-Industry Cooperation Foundation | Anti-l1cam antibodies and uses thereof |
| KR102887406B1 (ko) | 2018-07-26 | 2025-11-19 | 칠드런즈 호스피탈 메디칼 센터 | 간-담도-췌장 조직 및 이를 제조하는 방법 |
| AU2019339410A1 (en) | 2018-09-12 | 2021-04-15 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| WO2020160371A1 (en) | 2019-02-01 | 2020-08-06 | The University Of Hong Kong | Innervated organoid compositions and methods of making same |
| WO2020243633A1 (en) | 2019-05-31 | 2020-12-03 | Children's Hospital Medical Center | Shaped organoid compositions and methods of making same |
| WO2020243613A1 (en) | 2019-05-31 | 2020-12-03 | Children's Hospital Medical Center | Methods of generating and expanding hematopoietic stem cells |
| WO2023102120A1 (en) * | 2021-12-01 | 2023-06-08 | Memorial Sloan-Kettering Cancer Center | Organoid co-cultures and methods of use thereof |
| CN115078738A (zh) * | 2022-06-30 | 2022-09-20 | 复旦大学 | 一种l1cam蛋白n979位点特异性核心岩藻糖基化的抑制剂的应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007114550A1 (en) | 2006-04-03 | 2007-10-11 | Korea Research Institute Of Bioscience And Biotechnology | A novel monoclonal antibody specific to the l1cam, a hybridoma producing the same and a method producing the same |
| EP2054083B1 (en) * | 2006-08-23 | 2013-11-27 | Korea Research Institute of Bioscience and Biotechnology | A pharmaceutical composition for treating cholangiocarcinoma, a method for inhibiting growth or invasion of cholangiocarcinoma and a method for treating cholangiocarcinoma |
| AU2007221863A1 (en) * | 2006-10-16 | 2008-05-01 | Deutsches Krebsforschungszentrum Stiftung Des Offenftlichen Rechts | Treatment of chemotherapy -or radiothereapy-resistant tumors |
| WO2008046459A1 (en) * | 2006-10-16 | 2008-04-24 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Treatment of chemotherapy- or radiotherapy-resistant tumors using an l1 interfering molecule |
| PL2631248T3 (pl) | 2007-06-15 | 2018-06-29 | Medigene Ag | Leczenie nowotworów z użyciem specyficznego przeciwciała anty-L1 |
| AU2008201871A1 (en) * | 2008-04-16 | 2009-11-26 | Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts | Inhibition of angiogenesis and tumor metastasis |
| KR20100060351A (ko) * | 2008-11-27 | 2010-06-07 | 한국생명공학연구원 | Ｌ１ｃａｍ의 활성 또는 발현을 억제하는 물질 및 항암제를포함하는 항암용 조성물 |
| EP2571577A1 (en) * | 2010-05-17 | 2013-03-27 | Bristol-Myers Squibb Company | Improved immunotherapeutic dosing regimens and combinations thereof |
| WO2012005550A2 (ko) | 2010-07-08 | 2012-01-12 | 강원대학교산학협력단 | 담낭암 치료용 약제학적 조성물 및 이를 이용한 담낭암의 성장, 전이 억제 및 치료 방법 |
| EP2931899A1 (en) | 2012-12-12 | 2015-10-21 | The Broad Institute, Inc. | Functional genomics using crispr-cas systems, compositions, methods, knock out libraries and applications thereof |
| JP2016522679A (ja) | 2013-04-04 | 2016-08-04 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ＣＲＩＳＰＲ／Ｃａｓ系を用いたゲノム編集の治療的使用 |
| KR20160055923A (ko) | 2013-09-18 | 2016-05-18 | 메모리얼 슬로안-케터링 캔서 센터 | 암 전이 억제 |
| WO2015048577A2 (en) * | 2013-09-27 | 2015-04-02 | Editas Medicine, Inc. | Crispr-related methods and compositions |
| CN104829730A (zh) * | 2015-04-14 | 2015-08-12 | 苏静 | 一种能联合免疫细胞增强肿瘤杀伤能力的双特异性抗体及其制备方法和应用 |
-
2017
- 2017-08-02 CA CA3029653A patent/CA3029653A1/en active Pending
- 2017-08-02 AU AU2017306426A patent/AU2017306426B2/en active Active
- 2017-08-02 ES ES17837622T patent/ES3037528T3/es active Active
- 2017-08-02 EP EP25174512.1A patent/EP4623998A3/en active Pending
- 2017-08-02 WO PCT/US2017/045145 patent/WO2018026947A1/en not_active Ceased
- 2017-08-02 JP JP2019505179A patent/JP7751372B2/ja active Active
- 2017-08-02 EP EP17837622.4A patent/EP3493846B1/en active Active
- 2017-08-02 KR KR1020197006250A patent/KR20190036553A/ko not_active Ceased
- 2017-08-02 KR KR1020237042034A patent/KR20230170142A/ko active Pending
-
2018
- 2018-12-30 IL IL264024A patent/IL264024A/en unknown
-
2019
- 2019-01-31 US US16/263,677 patent/US11464874B2/en active Active
-
2022
- 2022-06-08 JP JP2022092913A patent/JP2022118058A/ja active Pending
- 2022-10-10 US US18/045,357 patent/US12059480B2/en active Active
-
2024
- 2024-08-12 US US18/800,616 patent/US20250213731A1/en active Pending
- 2024-12-31 AU AU2024287267A patent/AU2024287267A1/en active Pending
-
2025
- 2025-02-27 JP JP2025030120A patent/JP2025078664A/ja active Pending
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