JP2019523940A - 生物学的配列の自動アノテーションとスクリーニングのためのシステムおよび方法 - Google Patents
生物学的配列の自動アノテーションとスクリーニングのためのシステムおよび方法 Download PDFInfo
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- JP2019523940A JP2019523940A JP2018563706A JP2018563706A JP2019523940A JP 2019523940 A JP2019523940 A JP 2019523940A JP 2018563706 A JP2018563706 A JP 2018563706A JP 2018563706 A JP2018563706 A JP 2018563706A JP 2019523940 A JP2019523940 A JP 2019523940A
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/10—Sequence alignment; Homology search
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1089—Design, preparation, screening or analysis of libraries using computer algorithms
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B15/00—Systems controlled by a computer
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/20—Sequence assembly
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
- G16B50/30—Data warehousing; Computing architectures
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B99/00—Subject matter not provided for in other groups of this subclass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Theoretical Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Evolutionary Biology (AREA)
- Medical Informatics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Bioethics (AREA)
- Databases & Information Systems (AREA)
- Library & Information Science (AREA)
- General Physics & Mathematics (AREA)
- Automation & Control Theory (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022142326A JP2022181213A (ja) | 2016-06-10 | 2022-09-07 | 生物学的配列の自動アノテーションとスクリーニングのためのシステムおよび方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662348786P | 2016-06-10 | 2016-06-10 | |
| US62/348,786 | 2016-06-10 | ||
| US201662375858P | 2016-08-16 | 2016-08-16 | |
| US62/375,858 | 2016-08-16 | ||
| PCT/US2017/036868 WO2017214574A1 (en) | 2016-06-10 | 2017-06-09 | Systems and methods for automated annotation and screening of biological sequences |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022142326A Division JP2022181213A (ja) | 2016-06-10 | 2022-09-07 | 生物学的配列の自動アノテーションとスクリーニングのためのシステムおよび方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019523940A true JP2019523940A (ja) | 2019-08-29 |
| JP2019523940A5 JP2019523940A5 (show.php) | 2020-07-02 |
Family
ID=60574009
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018563706A Pending JP2019523940A (ja) | 2016-06-10 | 2017-06-09 | 生物学的配列の自動アノテーションとスクリーニングのためのシステムおよび方法 |
| JP2022142326A Pending JP2022181213A (ja) | 2016-06-10 | 2022-09-07 | 生物学的配列の自動アノテーションとスクリーニングのためのシステムおよび方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022142326A Pending JP2022181213A (ja) | 2016-06-10 | 2022-09-07 | 生物学的配列の自動アノテーションとスクリーニングのためのシステムおよび方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20170357752A1 (show.php) |
| EP (1) | EP3469499A4 (show.php) |
| JP (2) | JP2019523940A (show.php) |
| KR (1) | KR102476915B1 (show.php) |
| CN (1) | CN109564769A (show.php) |
| CA (1) | CA3027127A1 (show.php) |
| SG (1) | SG11201811025VA (show.php) |
| WO (1) | WO2017214574A1 (show.php) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3722442B1 (en) | 2013-08-05 | 2023-04-05 | Twist Bioscience Corporation | De novo synthesized gene libraries |
| US10669304B2 (en) | 2015-02-04 | 2020-06-02 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
| US9981239B2 (en) | 2015-04-21 | 2018-05-29 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
| CA2998169A1 (en) | 2015-09-18 | 2017-03-23 | Twist Bioscience Corporation | Oligonucleic acid variant libraries and synthesis thereof |
| US11512347B2 (en) | 2015-09-22 | 2022-11-29 | Twist Bioscience Corporation | Flexible substrates for nucleic acid synthesis |
| CN108603307A (zh) | 2015-12-01 | 2018-09-28 | 特韦斯特生物科学公司 | 功能化表面及其制备 |
| CN109996876A (zh) | 2016-08-22 | 2019-07-09 | 特韦斯特生物科学公司 | 从头合成的核酸文库 |
| CN110248724B (zh) | 2016-09-21 | 2022-11-18 | 特韦斯特生物科学公司 | 基于核酸的数据存储 |
| CN110366613A (zh) | 2016-12-16 | 2019-10-22 | 特韦斯特生物科学公司 | 免疫突触的变体文库及其合成 |
| SG11201907713WA (en) | 2017-02-22 | 2019-09-27 | Twist Bioscience Corp | Nucleic acid based data storage |
| AU2018234629A1 (en) | 2017-03-15 | 2019-10-17 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
| IL271205B2 (en) | 2017-06-12 | 2025-02-01 | Twist Bioscience Corp | Methods for assembling continuous nucleic acids |
| WO2018231864A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| WO2019051501A1 (en) | 2017-09-11 | 2019-03-14 | Twist Bioscience Corporation | PROTEINS BINDING TO GPCR AND METHODS OF SYNTHESIS |
| EP3697529B1 (en) | 2017-10-20 | 2023-05-24 | Twist Bioscience Corporation | Heated nanowells for polynucleotide synthesis |
| CA3088911A1 (en) | 2018-01-04 | 2019-07-11 | Twist Bioscience Corporation | Dna-based storage device and method for synthesizing polynucleotides using the device |
| IL278771B2 (en) | 2018-05-18 | 2025-09-01 | Twist Bioscience Corp | Polynucleotides, reagents and methods for nucleic acid hybridization |
| WO2020118121A1 (en) | 2018-12-06 | 2020-06-11 | Battelle Memorial Institute | Technologies for nucleotide sequence screening |
| US12357959B2 (en) | 2018-12-26 | 2025-07-15 | Twist Bioscience Corporation | Highly accurate de novo polynucleotide synthesis |
| KR20210143766A (ko) | 2019-02-26 | 2021-11-29 | 트위스트 바이오사이언스 코포레이션 | Glp1 수용체에 대한 변이체 핵산 라이브러리 |
| US11492728B2 (en) | 2019-02-26 | 2022-11-08 | Twist Bioscience Corporation | Variant nucleic acid libraries for antibody optimization |
| JP2022550497A (ja) | 2019-06-21 | 2022-12-02 | ツイスト バイオサイエンス コーポレーション | バーコードに基づいた核酸配列アセンブリ |
| EP4464827A3 (en) | 2019-09-23 | 2025-02-26 | Twist Bioscience Corporation | Variant nucleic acid libraries for crth2 |
| WO2021061842A1 (en) | 2019-09-23 | 2021-04-01 | Twist Bioscience Corporation | Variant nucleic acid libraries for single domain antibodies |
| BR112022021780A2 (pt) | 2020-04-27 | 2023-03-07 | Twist Bioscience Corp | Bibliotecas de ácido nucléico variantes para coronavírus |
| JP2023539245A (ja) | 2020-08-26 | 2023-09-13 | ツイスト バイオサイエンス コーポレーション | Glp1r変異体に関する方法および組成物 |
| WO2022047076A1 (en) | 2020-08-28 | 2022-03-03 | Twist Bioscience Corporation | Devices and methods for synthesis |
| WO2022086866A1 (en) | 2020-10-19 | 2022-04-28 | Twist Bioscience Corporation | Methods of synthesizing oligonucleotides using tethered nucleotides |
| EP4213158A1 (en) * | 2020-11-13 | 2023-07-19 | Ahead Biocomputing, Co. Ltd | Information processing device, information processing method, recording medium recording information processing program, and information processing system |
| AU2022209701A1 (en) | 2021-01-21 | 2023-08-31 | Twist Bioscience Corporation | Methods and compositions relating to adenosine receptors |
| WO2022204316A2 (en) | 2021-03-24 | 2022-09-29 | Twist Bioscience Corporation | Variant nucleic acid libraries for cd3 |
| WO2022271884A2 (en) | 2021-06-22 | 2022-12-29 | Twist Bioscience Corporation | Methods and compositions relating to covid antibody epitopes |
| EP4420127A4 (en) * | 2021-10-19 | 2025-09-17 | Battelle Memorial Institute | GENETIC ENGINEERING DETECTION TECHNOLOGIES |
| JP2024542194A (ja) | 2021-11-18 | 2024-11-13 | ツイスト バイオサイエンス コーポレーション | Dickkopf-1バリアント抗体及び使用方法 |
| EP4460516A2 (en) | 2022-01-03 | 2024-11-13 | Twist Bioscience Corporation | Bispecific sars-cov-2 antibodies and methods of use |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002536977A (ja) * | 1999-02-19 | 2002-11-05 | フェビット フェラリウス バイオテクノロジー ゲゼルシャフト ミット ベシュレンクテル ハフツング | ポリマーの製法 |
| JP2008511058A (ja) * | 2004-08-18 | 2008-04-10 | アボツト・モレキユラー・インコーポレイテツド | コンピュータシステムを用いるデータ品質および/または部分異数染色体の決定 |
| US20100292102A1 (en) * | 2009-05-14 | 2010-11-18 | Ali Nouri | System and Method For Preventing Synthesis of Dangerous Biological Sequences |
| US20150120265A1 (en) * | 2011-09-01 | 2015-04-30 | Genome Compiler Corporation | System for polynucleotide construct design, visualization and transactions to manufacture the same |
| JP2016527313A (ja) * | 2013-08-05 | 2016-09-08 | ツイスト バイオサイエンス コーポレーション | 新規合成した遺伝子ライブラリ |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5701256A (en) * | 1995-05-31 | 1997-12-23 | Cold Spring Harbor Laboratory | Method and apparatus for biological sequence comparison |
| US8808986B2 (en) * | 2008-08-27 | 2014-08-19 | Gen9, Inc. | Methods and devices for high fidelity polynucleotide synthesis |
| CN103797486A (zh) * | 2011-06-06 | 2014-05-14 | 皇家飞利浦有限公司 | 用于组装核酸序列数据的方法 |
| WO2014066635A1 (en) * | 2012-10-24 | 2014-05-01 | Complete Genomics, Inc. | Genome explorer system to process and present nucleotide variations in genome sequence data |
-
2017
- 2017-06-09 US US15/619,322 patent/US20170357752A1/en not_active Abandoned
- 2017-06-09 JP JP2018563706A patent/JP2019523940A/ja active Pending
- 2017-06-09 SG SG11201811025VA patent/SG11201811025VA/en unknown
- 2017-06-09 EP EP17811124.1A patent/EP3469499A4/en not_active Withdrawn
- 2017-06-09 CN CN201780048980.4A patent/CN109564769A/zh active Pending
- 2017-06-09 CA CA3027127A patent/CA3027127A1/en active Pending
- 2017-06-09 WO PCT/US2017/036868 patent/WO2017214574A1/en not_active Ceased
- 2017-06-09 KR KR1020197000811A patent/KR102476915B1/ko active Active
-
2022
- 2022-09-07 JP JP2022142326A patent/JP2022181213A/ja active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002536977A (ja) * | 1999-02-19 | 2002-11-05 | フェビット フェラリウス バイオテクノロジー ゲゼルシャフト ミット ベシュレンクテル ハフツング | ポリマーの製法 |
| JP2008511058A (ja) * | 2004-08-18 | 2008-04-10 | アボツト・モレキユラー・インコーポレイテツド | コンピュータシステムを用いるデータ品質および/または部分異数染色体の決定 |
| US20100292102A1 (en) * | 2009-05-14 | 2010-11-18 | Ali Nouri | System and Method For Preventing Synthesis of Dangerous Biological Sequences |
| US20150120265A1 (en) * | 2011-09-01 | 2015-04-30 | Genome Compiler Corporation | System for polynucleotide construct design, visualization and transactions to manufacture the same |
| JP2016527313A (ja) * | 2013-08-05 | 2016-09-08 | ツイスト バイオサイエンス コーポレーション | 新規合成した遺伝子ライブラリ |
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201811025VA (en) | 2019-01-30 |
| CA3027127A1 (en) | 2017-12-14 |
| US20170357752A1 (en) | 2017-12-14 |
| KR20190017932A (ko) | 2019-02-20 |
| EP3469499A1 (en) | 2019-04-17 |
| EP3469499A4 (en) | 2020-10-21 |
| CN109564769A (zh) | 2019-04-02 |
| KR102476915B1 (ko) | 2022-12-12 |
| WO2017214574A1 (en) | 2017-12-14 |
| JP2022181213A (ja) | 2022-12-07 |
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