JP2019521704A5 - - Google Patents
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- JP2019521704A5 JP2019521704A5 JP2019516099A JP2019516099A JP2019521704A5 JP 2019521704 A5 JP2019521704 A5 JP 2019521704A5 JP 2019516099 A JP2019516099 A JP 2019516099A JP 2019516099 A JP2019516099 A JP 2019516099A JP 2019521704 A5 JP2019521704 A5 JP 2019521704A5
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- JP
- Japan
- Prior art keywords
- seq
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- nucleic acid
- amino acid
- cdr
- Prior art date
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662346324P | 2016-06-06 | 2016-06-06 | |
| US62/346,324 | 2016-06-06 | ||
| US201662396767P | 2016-09-19 | 2016-09-19 | |
| US62/396,767 | 2016-09-19 | ||
| PCT/US2017/036178 WO2017214167A1 (en) | 2016-06-06 | 2017-06-06 | Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019521704A JP2019521704A (ja) | 2019-08-08 |
| JP2019521704A5 true JP2019521704A5 (cg-RX-API-DMAC7.html) | 2020-07-16 |
| JP7070932B2 JP7070932B2 (ja) | 2022-05-18 |
Family
ID=59071115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019516099A Active JP7070932B2 (ja) | 2016-06-06 | 2017-06-06 | Ｂａｆｆ－ｒ標的化キメラ抗原受容体修飾ｔ細胞及びその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US11161908B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3464371A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP7070932B2 (cg-RX-API-DMAC7.html) |
| KR (6) | KR20250084978A (cg-RX-API-DMAC7.html) |
| CN (2) | CN109311991B (cg-RX-API-DMAC7.html) |
| AU (2) | AU2017277269C1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3026640A1 (cg-RX-API-DMAC7.html) |
| IL (4) | IL308798A (cg-RX-API-DMAC7.html) |
| SG (1) | SG11201810887UA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017214167A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014100615A1 (en) | 2012-12-20 | 2014-06-26 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| EP3439675A4 (en) | 2016-04-08 | 2019-12-18 | Purdue Research Foundation | METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY |
| CA3026640A1 (en) * | 2016-06-06 | 2017-12-14 | City Of Hope | Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof |
| CN110582288B (zh) | 2017-02-28 | 2024-09-20 | 恩多塞特公司 | 用于car t细胞疗法的组合物和方法 |
| CN112055595B (zh) | 2018-01-22 | 2024-12-17 | 恩多塞特公司 | Car t细胞的使用方法 |
| JP7568224B2 (ja) | 2018-02-23 | 2024-10-16 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞療法のための配列決定法 |
| EP3897720A4 (en) * | 2018-12-19 | 2022-12-07 | City of Hope | BAFF-R BISPECIFIC T-LYMPHOCYTE ACTIVATING ANTIBODIES |
| JP7593646B2 (ja) * | 2019-02-20 | 2024-12-03 | シティ・オブ・ホープ | Ｂａｆｆ－ｒ／ｃｄ１９を標的としたキメラ抗原受容体修飾ｔ細胞とその使用 |
| US12023354B2 (en) | 2019-05-31 | 2024-07-02 | Case Western Reserve University | Targeting B cell activating factor receptor (BAFF-R) using ligand-based chimeric antigen receptor (CAR)-T cells |
| EP4041294A4 (en) * | 2019-10-01 | 2024-10-02 | Case Western Reserve University | TARGETING B-CELL ACTIVATING FACTOR RECEPTOR (BAFF-R) USING LIGAND-BASED CHIMERIC ANTIGEN RECEPTOR (CAR) T CELLS |
| WO2021163989A1 (en) * | 2020-02-21 | 2021-08-26 | Yinnuolai Biotech Ltd. | Anti-baff receptor antibodies and uses thereof |
| CN111499723B (zh) * | 2020-05-28 | 2021-04-09 | 广州百暨基因科技有限公司 | 一种嵌合抗原受体及其应用 |
| WO2022242710A1 (zh) * | 2021-05-19 | 2022-11-24 | 上海诗健生物科技有限公司 | 一种特异性识别baff-r的嵌合抗原受体分子及其应用 |
| JP2024528038A (ja) | 2021-07-29 | 2024-07-26 | ソノマ バイオセラピューティクス， インコーポレイテッド | 調節性ｔ細胞を標的として自己免疫疾患を処置するための滑膜細胞外マトリックス特異的キメラ抗原受容体 |
| CA3257911A1 (en) * | 2022-06-01 | 2023-12-07 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Recombinant receptors binding to the B-cell activating factor receptor and their uses |
| CN116143943B (zh) * | 2022-10-31 | 2023-09-01 | 邦恩泰(山东)生物医药科技集团股份有限公司 | 一种靶向baffr嵌合抗原受体、car-t细胞及应用 |
| WO2025006795A1 (en) * | 2023-06-30 | 2025-01-02 | Board Of Regents, The University Of Texas System | Tsyn-seq: a t cell synapse-based tumor antigen identification platform |
| CN117050195B (zh) * | 2023-10-13 | 2023-12-19 | 旭和（天津）医药科技有限公司 | 一种靶向baffr嵌合抗原受体、car-t细胞和应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| ATE139258T1 (de) | 1990-01-12 | 1996-06-15 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| EP0585287B1 (en) | 1990-07-10 | 1999-10-13 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| EP0746609A4 (en) | 1991-12-17 | 1997-12-17 | Genpharm Int | NON-HUMAN TRANSGENIC ANIMALS CAPABLE OF PRODUCING HETEROLOGOUS ANTIBODIES |
| US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
| US6066718A (en) | 1992-09-25 | 2000-05-23 | Novartis Corporation | Reshaped monoclonal antibodies against an immunoglobulin isotype |
| CN1671416B (zh) | 2001-07-12 | 2013-01-02 | 杰斐逊·富特 | 超人源化抗体 |
| MX2007008017A (es) * | 2004-12-31 | 2007-09-12 | Genentech Inc | Polipeptidos que se ligan a br3 y usos de los mismos. |
| WO2015164594A1 (en) * | 2014-04-23 | 2015-10-29 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (car) for use in therapy and methods for making the same |
| GB201412658D0 (en) * | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| KR20160016725A (ko) * | 2014-08-05 | 2016-02-15 | 주식회사 유영제약 | 암 세포에 과발현되는 IL13Rα2에 특이적으로 결합하는 키메라 항원 수용체로 변형된 T 세포 |
| CA3026640A1 (en) | 2016-06-06 | 2017-12-14 | City Of Hope | Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof |
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2017
- 2017-06-06 CA CA3026640A patent/CA3026640A1/en active Pending
- 2017-06-06 EP EP17731026.5A patent/EP3464371A1/en active Pending
- 2017-06-06 KR KR1020257017399A patent/KR20250084978A/ko active Pending
- 2017-06-06 KR KR1020237032847A patent/KR102815802B1/ko active Active
- 2017-06-06 JP JP2019516099A patent/JP7070932B2/ja active Active
- 2017-06-06 WO PCT/US2017/036178 patent/WO2017214167A1/en not_active Ceased
- 2017-06-06 AU AU2017277269A patent/AU2017277269C1/en active Active
- 2017-06-06 KR KR1020197000160A patent/KR102356864B1/ko active Active
- 2017-06-06 IL IL308798A patent/IL308798A/en unknown
- 2017-06-06 CN CN201780035645.0A patent/CN109311991B/zh active Active
- 2017-06-06 IL IL311985A patent/IL311985A/en unknown
- 2017-06-06 KR KR1020227019986A patent/KR102522419B1/ko active Active
- 2017-06-06 KR KR1020227002646A patent/KR102410360B1/ko active Active
- 2017-06-06 KR KR1020237012104A patent/KR102584944B1/ko active Active
- 2017-06-06 US US16/307,443 patent/US11161908B2/en active Active
- 2017-06-06 IL IL263385A patent/IL263385B2/en unknown
- 2017-06-06 SG SG11201810887UA patent/SG11201810887UA/en unknown
- 2017-06-06 IL IL297925A patent/IL297925B2/en unknown
- 2017-06-06 CN CN202210970028.2A patent/CN115960251A/zh active Pending
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2021
- 2021-09-03 US US17/466,968 patent/US12215162B2/en active Active
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2024
- 2024-06-20 AU AU2024204218A patent/AU2024204218A1/en active Pending
- 2024-11-25 US US18/958,507 patent/US20250092149A1/en active Pending