JP2019520038A5 - - Google Patents
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- Publication number
- JP2019520038A5 JP2019520038A5 JP2018554562A JP2018554562A JP2019520038A5 JP 2019520038 A5 JP2019520038 A5 JP 2019520038A5 JP 2018554562 A JP2018554562 A JP 2018554562A JP 2018554562 A JP2018554562 A JP 2018554562A JP 2019520038 A5 JP2019520038 A5 JP 2019520038A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- cancer
- cell receptor
- peptide according
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 22
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 11
- 108091008874 T cell receptors Proteins 0.000 claims 9
- 239000012634 fragment Substances 0.000 claims 9
- 210000001744 T-lymphocyte Anatomy 0.000 claims 6
- 210000004027 cell Anatomy 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 239000003446 ligand Substances 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 3
- 239000004480 active ingredient Substances 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 239000003085 diluting agent Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000012528 membrane Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 208000031261 Acute myeloid leukaemia Diseases 0.000 claims 1
- 108091023037 Aptamer Proteins 0.000 claims 1
- 208000010839 B-cell chronic lymphocytic leukemia Diseases 0.000 claims 1
- 208000003174 Brain Neoplasms Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 1
- 208000022072 Gallbladder Neoplasms Diseases 0.000 claims 1
- 208000031422 Lymphocytic Chronic B-Cell Leukemia Diseases 0.000 claims 1
- 102000043129 MHC class I family Human genes 0.000 claims 1
- 108091054437 MHC class I family Proteins 0.000 claims 1
- 102000043131 MHC class II family Human genes 0.000 claims 1
- 108091054438 MHC class II family Proteins 0.000 claims 1
- 208000033776 Myeloid Acute Leukemia Diseases 0.000 claims 1
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 claims 1
- 208000015914 Non-Hodgkin lymphomas Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 208000033749 Small cell carcinoma of the bladder Diseases 0.000 claims 1
- 206010041067 Small cell lung cancer Diseases 0.000 claims 1
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 1
- 208000002495 Uterine Neoplasms Diseases 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 208000006990 cholangiocarcinoma Diseases 0.000 claims 1
- 208000032852 chronic lymphocytic leukemia Diseases 0.000 claims 1
- 210000004443 dendritic cell Anatomy 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000012636 effector Substances 0.000 claims 1
- 210000003238 esophagus Anatomy 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 238000004108 freeze drying Methods 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 201000010175 gallbladder cancer Diseases 0.000 claims 1
- 206010017758 gastric cancer Diseases 0.000 claims 1
- 206010073071 hepatocellular carcinoma Diseases 0.000 claims 1
- 231100000844 hepatocellular carcinoma Toxicity 0.000 claims 1
- 230000003308 immunostimulating effect Effects 0.000 claims 1
- 108010028930 invariant chain Proteins 0.000 claims 1
- 239000012931 lyophilized formulation Substances 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 210000000822 natural killer cell Anatomy 0.000 claims 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 208000000587 small cell lung carcinoma Diseases 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
- 201000011549 stomach cancer Diseases 0.000 claims 1
- 239000003053 toxin Substances 0.000 claims 1
- 231100000765 toxin Toxicity 0.000 claims 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 1
- 201000007710 urinary bladder small cell neuroendocrine carcinoma Diseases 0.000 claims 1
- 206010046766 uterine cancer Diseases 0.000 claims 1
- 239000013598 vector Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021114872A JP2021181442A (ja) | 2016-04-21 | 2021-07-12 | 黒色腫およびその他のがんに対する免疫療法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662325773P | 2016-04-21 | 2016-04-21 | |
| GB201606919 | 2016-04-21 | ||
| US62/325,773 | 2016-04-21 | ||
| GB1606919.7 | 2016-04-21 | ||
| PCT/EP2017/059016 WO2017182395A1 (en) | 2016-04-21 | 2017-04-13 | Immunotherapy against melanoma and other cancers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021114872A Division JP2021181442A (ja) | 2016-04-21 | 2021-07-12 | 黒色腫およびその他のがんに対する免疫療法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019520038A JP2019520038A (ja) | 2019-07-18 |
| JP2019520038A5 true JP2019520038A5 (enExample) | 2020-05-07 |
Family
ID=58579156
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018554562A Pending JP2019520038A (ja) | 2016-04-21 | 2017-04-13 | 黒色腫およびその他のがんに対する免疫療法 |
| JP2021114872A Pending JP2021181442A (ja) | 2016-04-21 | 2021-07-12 | 黒色腫およびその他のがんに対する免疫療法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021114872A Pending JP2021181442A (ja) | 2016-04-21 | 2021-07-12 | 黒色腫およびその他のがんに対する免疫療法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10435455B1 (enExample) |
| JP (2) | JP2019520038A (enExample) |
| CL (3) | CL2018002969A1 (enExample) |
| CO (1) | CO2018012294A2 (enExample) |
| CR (3) | CR20200608A (enExample) |
| IL (1) | IL262503A (enExample) |
| MX (1) | MX2018012758A (enExample) |
| PH (1) | PH12018502159A1 (enExample) |
| SG (1) | SG10202006117QA (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105163745B (zh) | 2013-03-01 | 2020-06-12 | 美国卫生和人力服务部 | 从外周血中产生肿瘤反应性t细胞富集群的方法 |
| GB201408100D0 (en) * | 2014-05-07 | 2014-06-18 | Sec Dep For Health The | Detection method |
| GB201700621D0 (en) | 2017-01-13 | 2017-03-01 | Guest Ryan Dominic | Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue |
| BR112021006941A2 (pt) | 2018-10-19 | 2021-08-31 | The Francis Crick Institute Limited | Antígenos de câncer inovadores e métodos |
| BR112022000133A2 (pt) * | 2019-07-05 | 2022-04-12 | Enara Bio Ltd | Antígenos de câncer e métodos |
| MX2022007598A (es) | 2019-12-20 | 2022-09-23 | Instil Bio Uk Ltd | Dispositivos y métodos para el aislamiento de linfocitos infiltrantes de tumores y usos de los mismos. |
| CN119943275A (zh) * | 2024-12-13 | 2025-05-06 | 南方医科大学南方医院 | 神经酰胺作为标志物在预测肝细胞癌微血管侵犯风险中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001053312A1 (en) | 1999-12-23 | 2001-07-26 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
| CA2343602A1 (en) | 2000-04-18 | 2001-10-18 | Genset | Est's and encoded human proteins |
| CA2495389A1 (en) | 2002-08-19 | 2004-02-26 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| US8088976B2 (en) | 2005-02-24 | 2012-01-03 | Monsanto Technology Llc | Methods for genetic control of plant pest infestation and compositions thereof |
| ATE461215T1 (de) | 2005-09-05 | 2010-04-15 | Immatics Biotechnologies Gmbh | Tumor-assoziierte peptide, welche an unterschiedliche menschliche leukozytenantigene der klasse ii binden |
| US20080107668A1 (en) | 2006-08-30 | 2008-05-08 | Immunotope, Inc. | Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer |
| EP1961825A1 (en) * | 2007-02-26 | 2008-08-27 | INSERM (Institut National de la Santé et de la Recherche Medicale) | Method for predicting the occurrence of metastasis in breast cancer patients |
| GB201004551D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
| CA3115945A1 (en) * | 2011-05-12 | 2012-11-15 | Mdxhealth Research B.V. | Molecular markers in prostate cancer |
| WO2013151663A1 (en) | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of membrane proteins |
| GB201411037D0 (en) | 2014-06-20 | 2014-08-06 | Immatics Biotechnologies Gmbh | Novel immunotherapy against several tumors of the blood, in particular chronic lymphoid leukemai (CLL) |
-
2017
- 2017-04-13 CR CR20200608A patent/CR20200608A/es unknown
- 2017-04-13 CR CR20180551A patent/CR20180551A/es unknown
- 2017-04-13 SG SG10202006117QA patent/SG10202006117QA/en unknown
- 2017-04-13 CR CR20200607A patent/CR20200607A/es unknown
- 2017-04-13 MX MX2018012758A patent/MX2018012758A/es unknown
- 2017-04-13 JP JP2018554562A patent/JP2019520038A/ja active Pending
-
2018
- 2018-10-08 PH PH12018502159A patent/PH12018502159A1/en unknown
- 2018-10-18 CL CL2018002969A patent/CL2018002969A1/es unknown
- 2018-10-21 IL IL262503A patent/IL262503A/en unknown
- 2018-11-14 CO CONC2018/0012294A patent/CO2018012294A2/es unknown
-
2019
- 2019-07-05 US US16/503,882 patent/US10435455B1/en active Active
- 2019-07-05 US US16/503,901 patent/US10519216B2/en active Active
-
2020
- 2020-12-18 CL CL2020003293A patent/CL2020003293A1/es unknown
- 2020-12-18 CL CL2020003292A patent/CL2020003292A1/es unknown
-
2021
- 2021-07-12 JP JP2021114872A patent/JP2021181442A/ja active Pending