JP2019518437A - 多重／最適化ミスマッチ増幅（ｍｏｍａ）−がんの評価のためのリアルタイムｐｃｒ - Google Patents

多重／最適化ミスマッチ増幅（ｍｏｍａ）−がんの評価のためのリアルタイムｐｃｒ Download PDF

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JP2019518437A
JP2019518437A JP2018556974A JP2018556974A JP2019518437A JP 2019518437 A JP2019518437 A JP 2019518437A JP 2018556974 A JP2018556974 A JP 2018556974A JP 2018556974 A JP2018556974 A JP 2018556974A JP 2019518437 A JP2019518437 A JP 2019518437A
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cancer
snv
nucleic acid
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sample
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JP2019518437A5 (enExample
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ミッチェル，アオイ，トミタ
スタム，カール
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Medical College of Wisconsin
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Medical College of Wisconsin
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
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  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2018556974A 2016-04-29 2017-04-29 多重／最適化ミスマッチ増幅（ｍｏｍａ）−がんの評価のためのリアルタイムｐｃｒ Pending JP2019518437A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022029376A JP2022084647A (ja) 2016-04-29 2022-02-28 多重／最適化ミスマッチ増幅（ｍｏｍａ）－がんの評価のためのリアルタイムｐｃｒ

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662330043P 2016-04-29 2016-04-29
US62/330,043 2016-04-29
PCT/US2017/030291 WO2017190104A1 (en) 2016-04-29 2017-04-29 Multiplexed optimized mismatch amplification (moma)-real time pcr for assessing cancer

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JP2022029376A Division JP2022084647A (ja) 2016-04-29 2022-02-28 多重／最適化ミスマッチ増幅（ｍｏｍａ）－がんの評価のためのリアルタイムｐｃｒ

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JP2019518437A true JP2019518437A (ja) 2019-07-04
JP2019518437A5 JP2019518437A5 (enExample) 2020-06-18

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JP2018556974A Pending JP2019518437A (ja) 2016-04-29 2017-04-29 多重／最適化ミスマッチ増幅（ｍｏｍａ）−がんの評価のためのリアルタイムｐｃｒ
JP2022029376A Pending JP2022084647A (ja) 2016-04-29 2022-02-28 多重／最適化ミスマッチ増幅（ｍｏｍａ）－がんの評価のためのリアルタイムｐｃｒ

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US (1) US20200181681A1 (enExample)
EP (1) EP3449014A1 (enExample)
JP (2) JP2019518437A (enExample)
CN (1) CN109715826A (enExample)
AU (1) AU2017258799A1 (enExample)
BR (1) BR112018072195A2 (enExample)
CA (1) CA3022545A1 (enExample)
EA (1) EA201892491A1 (enExample)
IL (1) IL262640A (enExample)
MX (1) MX2018013223A (enExample)
WO (1) WO2017190104A1 (enExample)

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US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
US12221653B2 (en) 2010-05-18 2025-02-11 Natera, Inc. Methods for simultaneous amplification of target loci
US9677118B2 (en) 2014-04-21 2017-06-13 Natera, Inc. Methods for simultaneous amplification of target loci
US12152275B2 (en) 2010-05-18 2024-11-26 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
US10316362B2 (en) 2010-05-18 2019-06-11 Natera, Inc. Methods for simultaneous amplification of target loci
BR112013020220B1 (pt) 2011-02-09 2020-03-17 Natera, Inc. Método para determinar o estado de ploidia de um cromossomo em um feto em gestação
US20140100126A1 (en) 2012-08-17 2014-04-10 Natera, Inc. Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data
US20180173846A1 (en) 2014-06-05 2018-06-21 Natera, Inc. Systems and Methods for Detection of Aneuploidy
US11479812B2 (en) 2015-05-11 2022-10-25 Natera, Inc. Methods and compositions for determining ploidy
RU2760913C2 (ru) 2016-04-15 2021-12-01 Натера, Инк. Способы выявления рака легкого
GB201618485D0 (en) 2016-11-02 2016-12-14 Ucl Business Plc Method of detecting tumour recurrence
CA3042722A1 (en) * 2016-11-02 2018-05-11 The Medical College Of Wisconsin, Inc. Methods for assessing risk using mismatch amplification and statistical methods
CA3067637A1 (en) 2017-06-20 2018-12-27 The Medical College Of Wisconsin, Inc. Assessing transplant complication risk with total cell-free dna
US12084720B2 (en) 2017-12-14 2024-09-10 Natera, Inc. Assessing graft suitability for transplantation
US12024738B2 (en) 2018-04-14 2024-07-02 Natera, Inc. Methods for cancer detection and monitoring
US12234509B2 (en) 2018-07-03 2025-02-25 Natera, Inc. Methods for detection of donor-derived cell-free DNA
US11931674B2 (en) 2019-04-04 2024-03-19 Natera, Inc. Materials and methods for processing blood samples

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WO2011118603A1 (ja) * 2010-03-24 2011-09-29 凸版印刷株式会社 競合プライマーによる標的塩基配列の検出方法
WO2016028316A1 (en) * 2014-08-22 2016-02-25 Resolution Bioscience, Inc. Methods for quantitative genetic analysis of cell free dna

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DE69832158T2 (de) 1997-02-25 2006-08-10 Arizona Board Of Regents, Tempe Isolierung und strukturelle aufklärung der kryostatischen linearen und cyclo-depsipeptide dolastatin 16, dolastatin 17, und dolastatin 18
US20030148301A1 (en) * 1999-12-10 2003-08-07 Toshiya Aono Method of detecting nucleotide polymorphism
JP4116856B2 (ja) * 2002-10-02 2008-07-09 富士フイルム株式会社 １塩基多型の検出方法
US10077474B2 (en) * 2012-05-29 2018-09-18 Abbott Molecular, Inc. Method of designing primers, method of detecting single nucleotide polymorphisms (SNPs), method of distinguishing SNPs, and related primers, detectable oligonucleotides, and kits
US20140242582A1 (en) 2013-02-28 2014-08-28 Ariosa Diagnostics, Inc. Detection of genetic abnormalities using ligation-based detection and digital pcr
HK1252152A1 (zh) * 2015-04-30 2019-05-17 Medical College Of Wisconsin, Inc. 用於評估無細胞dna的多重優化錯配擴增(moma)實時pcr

Patent Citations (2)

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WO2011118603A1 (ja) * 2010-03-24 2011-09-29 凸版印刷株式会社 競合プライマーによる標的塩基配列の検出方法
WO2016028316A1 (en) * 2014-08-22 2016-02-25 Resolution Bioscience, Inc. Methods for quantitative genetic analysis of cell free dna

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AU2017258799A1 (en) 2018-12-20
US20200181681A1 (en) 2020-06-11
EP3449014A1 (en) 2019-03-06
BR112018072195A2 (pt) 2019-02-12
WO2017190104A1 (en) 2017-11-02
JP2022084647A (ja) 2022-06-07
CA3022545A1 (en) 2017-11-02
MX2018013223A (es) 2019-04-22
EA201892491A1 (ru) 2019-06-28
IL262640A (en) 2018-12-31
CN109715826A (zh) 2019-05-03

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