JP2019517364A - 感染した全膝関節形成術のための抗生物質分配スペーサ装置および方法 - Google Patents
感染した全膝関節形成術のための抗生物質分配スペーサ装置および方法 Download PDFInfo
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/38—Joints for elbows or knees
- A61F2/389—Tibial components
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/38—Joints for elbows or knees
- A61F2/3859—Femoral components
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
- A61F2/461—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of knees
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
- A61F2002/30672—Features concerning an interaction with the environment or a particular use of the prosthesis temporary
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
- A61F2002/30677—Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
- A61F2002/3068—Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body the pharmaceutical product being in a reservoir
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30878—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
- A61F2002/4615—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spacers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
- A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
- A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
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- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
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- Prostheses (AREA)
Abstract
Description
別の例示的な実施形態では、全膝関節置換を実施するために使用される全膝関節プロテーゼが提供され得る。全膝関節プロテーゼは、大腿骨の遠位端と結合するように適合され、一対の関節丘を有する大腿骨コンポーネントと、脛骨の近位端と結合するように適合され、脛骨トレイを有する脛骨コンポーネントと、スペーサと、を含むこととしてもよい。スペーサは、脛骨トレイと連動するように適合された係止部品を有する下面と、関節丘支持プラットフォームを有し、任意選択的に脛骨ポストを有する上面であって、関節丘支持プラットフォームの各々は上面上で対向する側に配置され、関節丘支持プラットフォームの各々は滑らかであり、更に関節丘支持プラットフォームの各々の表面は浅い陥没部を有する、上面と、内側貯蔵部を取り囲む中空外側部分を有し、その材料が流体不透過性である本体とを含むこととしてもよい。本体は、更にチャネルおよび流量制限部を有するポートを有し、チャネルは本体の中空外側部分を通って延び、流量制限部は、外力が存在しない場合にはポートに出入りする流体の流れを制限し、外力が加えられたときにはポートの中への流体の導入を許容する。スペーサの係止部品は脛骨コンポーネントの脛骨トレイに連結しており、大腿骨コンポーネントの関節丘の各々はスペーサの関節丘支持プラットフォームのうちの1つの中に配置される。
Claims (20)
- 脛骨トレイと連動するように適合された係止部品を備える下面と、
一対の関節丘支持プラットフォームを備える上面であって、前記関節丘支持プラットフォームの各々は前記上面上で対向する側に配置され、前記関節丘支持プラットフォームの各々は滑らかであり、前記関節丘支持プラットフォームの各々の表面は、更に、浅い陥没部を有する、上面と、
内側貯蔵部を取り囲む中空外側部分を有し、その材料が流体不透過性である本体と、を備え、
該本体は、更に、チャネルおよび流量制限部を備えるポートを有し、前記チャネルは前記本体の前記中空外側部分を通って延び、前記流量制限部は、外力が存在しない場合には前記ポートに出入りする流体の流れを制限し、外力が加えられたときには前記ポートの中への流体の導入を許容する、膝関節置換プロテーゼ用のスペーサ。 - 前記本体上の1つまたは複数の孔を通して、流体を前記内側貯蔵部から除去するように動作可能なポンプを更に備える、請求項1に記載のスペーサ。
- 前記本体は1つまたは複数の孔を有し、前記孔の各々は、流体が前記内側貯蔵部から前記孔を通って拡散することを許容する、請求項1に記載のスペーサ。
- 前記本体は前記ポートの周りに配置された放射線不透過性リングを更に備える、請求項1に記載のスペーサ。
- 前記ポートの前記流量制限部は前記本体から外向きに突出している、請求項1に記載のスペーサ。
- 前記流量制限部は可撓性を有する、請求項1に記載のスペーサ。
- 前記流量制限部は、弾性材料で所定位置に保持された剛体材料のプレートである、請求項1に記載のスペーサ。
- ポリエチレンまたは炭素複合材料のうちの少なくとも1つから構成されている、請求項1に記載のスペーサ。
- 前記スペーサの前記上面上に配置されて前記上面から垂直に延びる脛骨ポストを更に備え、前記脛骨ポストは前記関節丘支持プラットフォームの間の中央に位置する、請求項1に記載のスペーサ。
- 大腿骨の遠位端と結合するように適合され、一対の関節丘を有する大腿骨コンポーネントと、
脛骨の近位端と結合するように適合され、脛骨トレイを備える脛骨コンポーネントと、
スペーサと、を備え、
該スペーサは、
前記脛骨トレイと連動するように適合された係止部品を備える下面と、
一対の関節丘支持プラットフォームを備える上面であって、前記関節丘支持プラットフォームの各々は前記上面上で対向する側に配置され、前記関節丘支持プラットフォームの各々は滑らかであり、更に前記関節丘支持プラットフォームの各々の表面は浅い陥没部を有する、上面と、
および、内側貯蔵部を取り囲む中空外側部分を有しその材料が流体不透過性である本体と、を備え、
該本体は、更に、チャネルおよび流量制限部を備えるポートを有し、前記チャネルは前記本体の前記中空外側部分を通って延び、前記流量制限部は、外力が存在しない場合には前記ポートに出入りする流体の流れを制限し、外力が加えられたときには前記ポートの中への流体の導入を許容し、
前記スペーサの前記係止部品は前記脛骨コンポーネントの前記脛骨トレイに連結しており、前記大腿骨コンポーネントの前記関節丘の各々は前記スペーサの前記関節丘支持プラットフォームのうちの1つの中に配置される、全膝関節プロテーゼ。 - 前記本体上の1つまたは複数の孔を通して、流体を前記内側貯蔵部から除去するように動作可能なポンプを更に備える、請求項10に記載の全膝関節プロテーゼ。
- 前記本体は1つまたは複数の孔を有し、前記孔の各々は、流体が前記内側貯蔵部から前記孔を通って拡散することを許容する、請求項10に記載の全膝関節プロテーゼ。
- 前記本体は前記ポートの周りに配置された放射線不透過性リングを更に備える、請求項10に記載の全膝関節プロテーゼ。
- 前記流量制限部は可撓性を有する、請求項10に記載の全膝関節プロテーゼ。
- 前記流量制限部は、弾性材料で所定位置に保持された剛体材料のプレートである、請求項10に記載の全膝関節プロテーゼ。
- 前記スペーサはポリエチレンまたは炭素複合材料のうちの少なくとも1つから構成されている、請求項10に記載の全膝関節プロテーゼ。
- 前記スペーサの前記係止部品と前記脛骨コンポーネントの前記脛骨トレイとの間の接続が、固定ベアリング接続または回転プラットフォーム接続のうちの少なくとも1つである、請求項10に記載の全膝関節プロテーゼ。
- 前記スペーサは、前記スペーサの前記上面に配置され前記上面から垂直に延びる脛骨ポストを更に備え、前記脛骨ポストは前記関節丘支持プラットフォームの間の中央に位置する、請求項10に記載の全膝関節プロテーゼ。
- 前記全膝関節プロテーゼが、後方安定型プロテーゼ、十字靱帯温存型プロテーゼ、または十字靱帯切除型プロテーゼのうちの少なくとも1つである、請求項10に記載の全膝関節プロテーゼ。
- 前記スペーサの前記係止部品は前記脛骨コンポーネントの前記脛骨トレイに恒久的に連結される、請求項10に記載の全膝関節プロテーゼ。
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US15/178,707 | 2016-06-10 | ||
US15/178,707 US9839523B1 (en) | 2016-06-10 | 2016-06-10 | Antibiotic dispensing spacer apparatus and method for infected total knee arthroplasty |
PCT/US2017/034153 WO2017213852A1 (en) | 2016-06-10 | 2017-05-24 | Antibiotic dispensing spacer apparatus and method for infected total knee arthroplasty |
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JP2019517364A true JP2019517364A (ja) | 2019-06-24 |
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EP (1) | EP3468508B1 (ja) |
JP (1) | JP2019517364A (ja) |
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US10993810B2 (en) * | 2015-02-16 | 2021-05-04 | Cossington Limited | Containment body for a spacer device and method of making thereof |
GB2535767A (en) * | 2015-02-27 | 2016-08-31 | Idr-Biomed Ltd | Buffer for femoral head and neck excision |
US9839523B1 (en) * | 2016-06-10 | 2017-12-12 | Jared Ruben Hillel FORAN | Antibiotic dispensing spacer apparatus and method for infected total knee arthroplasty |
US10022233B1 (en) * | 2017-12-04 | 2018-07-17 | Duke University | Orthopedic implant for sustained drug release |
WO2019143689A1 (en) * | 2018-01-17 | 2019-07-25 | Mako Surgical Corp. | Systems and methods for robotic infection treatment of a prosthesis |
DE102018106704B4 (de) * | 2018-03-21 | 2021-06-24 | Heraeus Medical Gmbh | Kniespacersystem mit Spülvorrichtung |
DE102018106705B4 (de) | 2018-03-21 | 2021-05-27 | Heraeus Medical Gmbh | Femoraler Hüftgelenkspacer mit Sprühvorrichtung |
WO2019226805A1 (en) * | 2018-05-22 | 2019-11-28 | West Virginia University | Selective targeted release |
WO2020092882A1 (en) * | 2018-11-01 | 2020-05-07 | Forcast Orthopedics, Inc. | Prosthetic knee spacer and method of using the same |
WO2021142688A1 (zh) * | 2020-01-13 | 2021-07-22 | 丽水市人民医院 | 一种用于膝关节置换后感染的间隔引流装置 |
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EP3468508A4 (en) | 2019-12-25 |
WO2017213852A1 (en) | 2017-12-14 |
US20180008423A1 (en) | 2018-01-11 |
EP3468508A1 (en) | 2019-04-17 |
CN109310505A (zh) | 2019-02-05 |
US10265182B2 (en) | 2019-04-23 |
CN109310505B (zh) | 2020-12-29 |
EP3468508B1 (en) | 2021-03-03 |
US9839523B1 (en) | 2017-12-12 |
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