JP2019516375A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019516375A5 JP2019516375A5 JP2018560186A JP2018560186A JP2019516375A5 JP 2019516375 A5 JP2019516375 A5 JP 2019516375A5 JP 2018560186 A JP2018560186 A JP 2018560186A JP 2018560186 A JP2018560186 A JP 2018560186A JP 2019516375 A5 JP2019516375 A5 JP 2019516375A5
- Authority
- JP
- Japan
- Prior art keywords
- allele
- pos
- nuclear position
- snp
- nuclear
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022044738A JP7392020B2 (ja) | 2016-05-20 | 2022-03-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2023213224A JP2024037945A (ja) | 2016-05-20 | 2023-12-18 | 遺伝子に基づく炎症性腸疾患の診断 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662339357P | 2016-05-20 | 2016-05-20 | |
| US62/339,357 | 2016-05-20 | ||
| PCT/US2017/033625 WO2017201461A1 (en) | 2016-05-20 | 2017-05-19 | Diagnosis of inflammatory bowel disease based on genes |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022044738A Division JP7392020B2 (ja) | 2016-05-20 | 2022-03-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2023213224A Division JP2024037945A (ja) | 2016-05-20 | 2023-12-18 | 遺伝子に基づく炎症性腸疾患の診断 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019516375A JP2019516375A (ja) | 2019-06-20 |
| JP2019516375A5 true JP2019516375A5 (OSRAM) | 2020-06-18 |
| JP7475811B2 JP7475811B2 (ja) | 2024-04-30 |
Family
ID=60326226
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018560186A Active JP7475811B2 (ja) | 2016-05-20 | 2017-05-19 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2022044738A Active JP7392020B2 (ja) | 2016-05-20 | 2022-03-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2023213224A Pending JP2024037945A (ja) | 2016-05-20 | 2023-12-18 | 遺伝子に基づく炎症性腸疾患の診断 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022044738A Active JP7392020B2 (ja) | 2016-05-20 | 2022-03-18 | 遺伝子に基づく炎症性腸疾患の診断 |
| JP2023213224A Pending JP2024037945A (ja) | 2016-05-20 | 2023-12-18 | 遺伝子に基づく炎症性腸疾患の診断 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11549146B2 (OSRAM) |
| EP (1) | EP3458466B1 (OSRAM) |
| JP (3) | JP7475811B2 (OSRAM) |
| KR (4) | KR20230003433A (OSRAM) |
| CN (2) | CN109476698B (OSRAM) |
| WO (1) | WO2017201461A1 (OSRAM) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110229471A1 (en) | 2008-11-26 | 2011-09-22 | Cedars-Sinai Medical Center | Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease |
| CN109462996A (zh) | 2016-03-17 | 2019-03-12 | 西达-赛奈医疗中心 | 通过rnaset2诊断炎性肠病的方法 |
| CN109476698B (zh) * | 2016-05-20 | 2023-10-17 | 西达-赛奈医疗中心 | 基于基因的炎性肠病诊断 |
| KR20220088529A (ko) | 2019-05-14 | 2022-06-27 | 프로메테우스 바이오사이언시즈, 인크. | Tl1a 환자 선택 방법, 시스템 및 장치 |
| CA3187966A1 (en) * | 2020-06-26 | 2021-12-30 | Pfizer Inc. | Methods of treating inflammatory bowel disease with tl1a antibodies |
| MX2023005688A (es) * | 2020-11-13 | 2023-07-18 | Prometheus Biosciences Inc | Metodos, sistemas y equipos para el tratamiento de enfermedades inflamatorias dirigidas al tl1a. |
| CN115851911B (zh) * | 2022-11-25 | 2025-10-24 | 南京鼓楼医院 | 一种用于鉴别狼疮性肾炎的尿液外泌体tsRNA标志物和探针及其应用 |
| WO2024148218A2 (en) * | 2023-01-06 | 2024-07-11 | Prometheus Biosciences, Inc. | Methods of treating inflammatory diseases with combination of tl1a inhibitors and tnf inhibitors |
| WO2025038473A1 (en) | 2023-08-11 | 2025-02-20 | Paragon Therapeutics, Inc. | Tl1a binding antibodies and methods of use |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4443421A (en) | 1982-03-16 | 1984-04-17 | Occidental Chemical Corporation | Process for removing particulate impurities from aqueous phosphoric acid |
| WO1986001429A1 (fr) | 1984-08-27 | 1986-03-13 | Toray Industries, Inc. | Appareil de separation entre un solide et un liquide |
| US5000850A (en) | 1986-09-10 | 1991-03-19 | Engelhard Corporation | Apparatus for dewatering an aqueous clay suspension |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US7357927B2 (en) | 1996-03-12 | 2008-04-15 | Human Genome Sciences, Inc. | Death domain containing receptors |
| EP1100962A1 (en) | 1998-07-25 | 2001-05-23 | AstraZeneca AB | Genetic polymorphisms in the human neurokinin 1 receptor gene and their uses in diagnosis and treatment of diseases |
| JP2004194534A (ja) | 2002-12-17 | 2004-07-15 | Sumitomo Pharmaceut Co Ltd | 炎症性腸疾患疾患マーカーおよびその利用 |
| CA2541138A1 (en) * | 2003-10-06 | 2005-05-06 | Novartis Ag | Use of genetic polymorphisms that associate with efficacy of treatment of inflammatory disease |
| WO2006048291A2 (en) | 2004-11-03 | 2006-05-11 | Almac Diagnostics Limited | Transcriptome microarray technology and methods of using the same |
| JP5065253B2 (ja) | 2005-05-06 | 2012-10-31 | ザイモジェネティクス， インコーポレイテッド | Ｉｌ−３１モノクローナル抗体とその使用法 |
| WO2006127900A2 (en) | 2005-05-25 | 2006-11-30 | Biogen Idec Ma Inc. | Tl1a in the treatment of disease |
| US20090181380A1 (en) * | 2005-12-19 | 2009-07-16 | Abdelmajid Belouchi | Genemap of the human genes associated with crohn's disease |
| US20090018031A1 (en) | 2006-12-07 | 2009-01-15 | Switchgear Genomics | Transcriptional regulatory elements of biological pathways tools, and methods |
| US20110217310A1 (en) | 2007-01-10 | 2011-09-08 | Siegel Richard M | Blockade of tl1a-dr3 interactions to ameliorate t cell mediated disease pathology |
| JP2010517582A (ja) * | 2007-02-12 | 2010-05-27 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 結腸癌の早期検出および予後診断の方法 |
| US20100190162A1 (en) * | 2007-02-26 | 2010-07-29 | Cedars-Sinai Medical Center | Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease |
| WO2008106579A2 (en) | 2007-02-28 | 2008-09-04 | Cedars-Sinai Medical Center | The role of il-12, il-23 and il-17 receptors in inflammatory bowel disease |
| US20150376707A1 (en) * | 2007-05-18 | 2015-12-31 | Cedars-Sinai Medical Center | Methods of diagnosing and treating inflammatory bowel disease |
| US8118175B2 (en) | 2007-07-18 | 2012-02-21 | Siemens Industry, Inc. | Venting device for a disc filter |
| WO2009039244A2 (en) * | 2007-09-18 | 2009-03-26 | Genizon Biosciences Inc. | Genemap of the human genes associated with crohn's disease |
| US20100240043A1 (en) | 2007-10-19 | 2010-09-23 | Cedars-Sinai Medical Center | Methods of using genetic variants to diagnose and predict inflammatory bowel disease |
| NZ585559A (en) | 2007-11-13 | 2012-11-30 | Teva Biopharmaceuticals Usa Inc | Humanized antibodies against tl1a |
| US8815508B2 (en) | 2008-08-12 | 2014-08-26 | Zinfandel Pharmaceuticals, Inc. | Method of identifying disease risk factors |
| BRPI0917379A2 (pt) | 2008-08-29 | 2015-11-17 | Centocor Ortho Biotech Inc | marcadores e metodos para avaliar e tratar colite ulcerativa e desordens relacionadas usando um painel de 20 genes |
| JP2010088432A (ja) | 2008-09-09 | 2010-04-22 | Kansetsu Saisei Kenkyusho:Kk | Ｔｎｆ阻害薬治療による有効性・副作用発現に関する多型、およびその利用 |
| US20110229471A1 (en) * | 2008-11-26 | 2011-09-22 | Cedars-Sinai Medical Center | Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease |
| US9580752B2 (en) * | 2008-12-24 | 2017-02-28 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy |
| CA2758531C (en) | 2009-04-14 | 2018-11-13 | Derren Barken | Inflammatory bowel disease prognostics |
| US20130136720A1 (en) | 2010-01-15 | 2013-05-30 | Cedars-Sinai Medical Center | Methods of using fut2 genetic variants to diagnose crohn's disease |
| WO2011153501A2 (en) * | 2010-06-04 | 2011-12-08 | Prometheus Laboratories Inc. | Methods for improving inflammatory bowel disease diagnosis |
| US8766034B2 (en) | 2010-09-22 | 2014-07-01 | Cedars-Sinai Medical Center | TL1A model of inflammation fibrosis and autoimmunity |
| EP3260540A1 (en) | 2010-11-12 | 2017-12-27 | The General Hospital Corporation | Polycomb-associated non-coding rnas |
| US9902996B2 (en) * | 2011-02-11 | 2018-02-27 | Cedars-Sinai Medical Center | Methods of predicting the need for surgery in crohn's disease |
| RU2013154566A (ru) | 2011-05-10 | 2015-06-20 | Нестек С.А. | Способы анализа профиля активности болезни с целью проведения индивидуального лечения |
| EP2710147A1 (en) | 2011-05-18 | 2014-03-26 | Rheinische Friedrich-Wilhelms-Universität Bonn | Molecular analysis of acute myeloid leukemia |
| KR20140104344A (ko) | 2011-05-20 | 2014-08-28 | 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 시크리터리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비시스 | Ｔ 세포 매개성 질병의 병증을 개선하기 위한 ｔｌ１ａ-ｄｒ３의 상호작용의 차단 및 그것의 항체 |
| HRP20211582T1 (hr) | 2011-06-03 | 2022-01-07 | Xoma Technology Ltd. | Protutijela specifična za tgf-beta |
| WO2013059732A1 (en) | 2011-10-21 | 2013-04-25 | Nestec S.A. | Methods for improving inflammatory bowel disease diagnosis |
| EP2812445A2 (en) | 2012-02-10 | 2014-12-17 | Novo Nordisk A/S | Methods related to treatment of inflammatory diseases and disorders |
| AU2014241162A1 (en) | 2013-03-27 | 2015-10-22 | Cedars-Sinai Medical Center | Mitigation and reversal of fibrosis and inflammation by inhibition of TL1A function and related signaling pathways |
| EP2997165A4 (en) | 2013-05-17 | 2017-03-08 | Cedars-Sinai Medical Center | Variants of tnfsf15 and dcr3 associated with crohn's disease |
| CA2923651C (en) * | 2013-10-09 | 2023-03-14 | Cedars-Sinai Medical Center | Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease |
| WO2015138774A1 (en) * | 2014-03-13 | 2015-09-17 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| WO2016170348A2 (en) | 2015-04-22 | 2016-10-27 | Mina Therapeutics Limited | Sarna compositions and methods of use |
| IL261228B2 (en) | 2016-02-26 | 2023-12-01 | Nanotech Energy Inc | Methods, devices and systems for processing preparations containing carbon |
| CN109476698B (zh) | 2016-05-20 | 2023-10-17 | 西达-赛奈医疗中心 | 基于基因的炎性肠病诊断 |
| US10041044B2 (en) | 2016-07-29 | 2018-08-07 | Trustees Of Boston University | Age-associated clonal hematopoiesis accelerates cardio-metabolic disease development |
| KR20240128132A (ko) | 2016-10-26 | 2024-08-23 | 세다르스-신나이 메디칼 센터 | 중화 항-tl1a 단일 클론 항체 |
| US20210254056A1 (en) | 2017-05-05 | 2021-08-19 | Camp4 Therapeutics Corporation | Identification and targeted modulation of gene signaling networks |
| WO2020121618A1 (ja) | 2018-12-14 | 2020-06-18 | 株式会社フジクラ | フェルール、ファイバ付きフェルール及びファイバ付きフェルールの製造方法 |
-
2017
- 2017-05-19 CN CN201780044934.7A patent/CN109476698B/zh active Active
- 2017-05-19 KR KR1020227044940A patent/KR20230003433A/ko not_active Ceased
- 2017-05-19 KR KR1020227003985A patent/KR102481305B1/ko active Active
- 2017-05-19 KR KR1020187037151A patent/KR20190016972A/ko not_active Ceased
- 2017-05-19 KR KR1020247019512A patent/KR20240095363A/ko not_active Ceased
- 2017-05-19 WO PCT/US2017/033625 patent/WO2017201461A1/en not_active Ceased
- 2017-05-19 EP EP17800279.6A patent/EP3458466B1/en active Active
- 2017-05-19 JP JP2018560186A patent/JP7475811B2/ja active Active
- 2017-05-19 US US16/303,033 patent/US11549146B2/en active Active
- 2017-05-19 CN CN202311263442.0A patent/CN117286238A/zh active Pending
-
2022
- 2022-03-18 JP JP2022044738A patent/JP7392020B2/ja active Active
- 2022-12-09 US US18/063,931 patent/US20230366028A1/en active Pending
-
2023
- 2023-12-18 JP JP2023213224A patent/JP2024037945A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019516375A5 (OSRAM) | ||
| JP2012080900A5 (OSRAM) | ||
| JP2012503985A5 (OSRAM) | ||
| JP2018038436A5 (OSRAM) | ||
| JP2009528060A5 (OSRAM) | ||
| JP2016041070A5 (OSRAM) | ||
| CA2938731A1 (en) | Methods of treating alzheimer's disease | |
| JP2013532494A5 (OSRAM) | ||
| JP2014533949A5 (OSRAM) | ||
| JP2011528903A5 (OSRAM) | ||
| RU2018122965A (ru) | Улучшенный способ и набор для определения тяжести и прогрессирования периодонтального заболевания | |
| JP2010528590A5 (OSRAM) | ||
| JP2013544536A5 (OSRAM) | ||
| Schorderet et al. | IROme, a New High‐Throughput Molecular Tool for the Diagnosis of Inherited Retinal Dystrophies | |
| Ortiz et al. | Electrochemical detection of single-nucleotide polymorphism associated with rifampicin resistance in Mycobacterium tuberculosis using solid-phase primer elongation with ferrocene-linked redox-labeled nucleotides | |
| Jauset-Rubio et al. | Solid-phase primer elongation using biotinylated dNTPs for the detection of a single nucleotide polymorphism from a fingerprick blood sample | |
| AU2015213570B2 (en) | NGS systems control and methods involving the same | |
| JP2020092721A5 (OSRAM) | ||
| Wang et al. | Development of high-resolution melting analysis for the detection of the MYD88 L265P mutation | |
| Sloane et al. | Rapid KRAS mutation detection via hybridization-induced aggregation of microbeads | |
| KR101287431B1 (ko) | 표적 유전자의 다양한 변이가 존재하는 유전자 영역을 증폭하기 위한 프라이머 조성물, 이를 이용한 표적 유전자 증폭 방법 및 이를 포함하는 ｐｃｒ 증폭 키트 그리고 이를 이용한 표적 유전자의 유전자형 분석방법 | |
| Randhawa et al. | A novel Tetra-primer ARMS-PCR based assay for genotyping SNP rs12303764 (G/T) of human Unc-51 like kinase 1 gene | |
| Papanikos et al. | Lateral flow dipstick test for genotyping of 15 beta-globin gene (HBB) mutations with naked-eye detection | |
| JP2008306974A (ja) | Ｈｃｖ遺伝子型判定方法、並びに、これに用いるｌｎａプローブ及びキット | |
| Niihara et al. | Simple and rapid detection of HLA-A* 31: 01 for prediction of carbamazepine-induced hypersensitivity using loop-mediated isothermal amplification method |