JP2019515648A5 - - Google Patents

Download PDF

Info

Publication number
JP2019515648A5
JP2019515648A5 JP2018545380A JP2018545380A JP2019515648A5 JP 2019515648 A5 JP2019515648 A5 JP 2019515648A5 JP 2018545380 A JP2018545380 A JP 2018545380A JP 2018545380 A JP2018545380 A JP 2018545380A JP 2019515648 A5 JP2019515648 A5 JP 2019515648A5
Authority
JP
Japan
Prior art keywords
residue
antibody
seq
sequence
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018545380A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019515648A (ja
JP7053479B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2017/000293 external-priority patent/WO2017149394A1/en
Publication of JP2019515648A publication Critical patent/JP2019515648A/ja
Publication of JP2019515648A5 publication Critical patent/JP2019515648A5/ja
Application granted granted Critical
Publication of JP7053479B2 publication Critical patent/JP7053479B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018545380A 2016-02-29 2017-02-28 IL7受容体細胞外ドメインα鎖に対する非拮抗性抗体及び癌治療におけるそれらの使用 Active JP7053479B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662301271P 2016-02-29 2016-02-29
US62/301,271 2016-02-29
PCT/IB2017/000293 WO2017149394A1 (en) 2016-02-29 2017-02-28 Non-antagonistic antibodies directed against the alpha chain of the il7 receptor extracellular domain and use thereof in cancer treatment

Publications (3)

Publication Number Publication Date
JP2019515648A JP2019515648A (ja) 2019-06-13
JP2019515648A5 true JP2019515648A5 (https=) 2020-04-16
JP7053479B2 JP7053479B2 (ja) 2022-04-12

Family

ID=58530580

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018545380A Active JP7053479B2 (ja) 2016-02-29 2017-02-28 IL7受容体細胞外ドメインα鎖に対する非拮抗性抗体及び癌治療におけるそれらの使用

Country Status (22)

Country Link
US (1) US11230602B2 (https=)
EP (1) EP3423496B1 (https=)
JP (1) JP7053479B2 (https=)
KR (1) KR102819051B1 (https=)
CN (1) CN109195987B (https=)
AU (1) AU2017225495B2 (https=)
CY (1) CY1122072T1 (https=)
DK (1) DK3423496T3 (https=)
ES (1) ES2737307T3 (https=)
HR (1) HRP20191445T1 (https=)
HU (1) HUE045183T2 (https=)
IL (1) IL261330B2 (https=)
LT (1) LT3423496T (https=)
MA (1) MA43767B1 (https=)
MD (1) MD3423496T2 (https=)
ME (1) ME03446B (https=)
PL (1) PL3423496T3 (https=)
PT (1) PT3423496T (https=)
RS (1) RS59223B1 (https=)
SI (1) SI3423496T1 (https=)
SM (1) SMT201900460T1 (https=)
WO (1) WO2017149394A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2955196A1 (en) 2014-06-10 2015-12-16 Effimune Antibodies directed against CD127
WO2019043065A1 (en) * 2017-08-29 2019-03-07 Ose Immunotherapeutics METHOD AND PREPARATION FOR SORTING T EFFECTOR LYMPHOCYTES USING ANTI-CD127 ANTIBODIES FOR CELL THERAPY APPLICATIONS
AU2019265888B2 (en) * 2018-05-10 2026-04-09 Neuracle Science Co., Ltd. Anti-family with sequence similarity 19, member A5 antibodies and method of use thereof
US20220273713A1 (en) * 2019-06-28 2022-09-01 The University Of Melbourne Method of inhibiting or activating gamma delta t cells
EP4065605A4 (en) 2019-11-26 2023-07-12 Ramot at Tel-Aviv University Ltd. Antibodies to carbohydrate antigens
CN110894237B (zh) * 2019-12-05 2021-08-03 山东省分析测试中心 抗cd127的抗体、分泌该抗体的细胞株及其制备方法和应用
WO2021222227A1 (en) * 2020-04-27 2021-11-04 Memorial Sloan-Kettering Cancer Center Chimeric antigen receptors targeting cd127 and use thereof
AU2021275055A1 (en) * 2020-05-18 2023-02-02 Mouhannad Jumaa Composition for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia
CN113501878B (zh) * 2021-02-03 2022-12-02 北京智仁美博生物科技有限公司 针对人tslp的多种抗体及其用途
US20220389104A1 (en) * 2021-05-28 2022-12-08 Ose Immunotherapeutics Method for Treating CD127-Positive Cancers by Administering an Anti-CD127 Agent

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19742706B4 (de) 1997-09-26 2013-07-25 Pieris Proteolab Ag Lipocalinmuteine
ES2686593T3 (es) 2006-05-31 2018-10-18 The Regents Of The University Of California Expresión de CD127 que correlaciona inversamente con FoxP3 y la función supresora de Treg CD4+
EP1930342B1 (en) 2006-12-04 2012-01-25 Institut Pasteur OB-fold used as scaffold for engineering new specific binders
GB0724051D0 (en) 2007-12-08 2008-01-16 Medical Res Council Mutant proteins and methods for producing them
UY32038A (es) 2008-08-08 2010-03-26 Glaxo Wellcome Mfg Pte Ltd Inmunoblobulinas anti-cd127 y sus usos
WO2010085643A1 (en) 2009-01-22 2010-07-29 University Of Miami Targeting il-7 signaling as a therapy for multiple sclerosis and other il-7 signaling dependent disorders
PE20170687A1 (es) * 2010-01-28 2017-06-13 Glaxo Group Ltd Proteinas de enlace a cd127
AR080291A1 (es) 2010-02-24 2012-03-28 Rinat Neuroscience Corp Anticuerpos antagonistas anti receptor de il-7 y procedimientos
EP2583980A1 (en) 2011-10-19 2013-04-24 Effimune Antibodies directed against the alpha chain of IL7 receptor - their use for the preparation of drug candidates
US20150297310A1 (en) * 2014-04-17 2015-10-22 Georgia Regents Research Institute, Inc. Methods for selecting a treatment for cancer
EP2955196A1 (en) 2014-06-10 2015-12-16 Effimune Antibodies directed against CD127

Similar Documents

Publication Publication Date Title
JP2019515648A5 (https=)
JP7549621B2 (ja) O-アセチル化GD2ガングリオシド(OAcGD2)に対するヒト化抗体
TWI701259B (zh) 4﹘1bb抗體及其製備方法和應用
ES2975063T3 (es) Anti-CD25 optimizado para FC para el agotamiento celular específico de tumores
JP2026001061A (ja) 抗dll3キメラ抗原受容体及びその使用
HRP20191445T1 (hr) Ne-antagonistička antitijela usmjerena protiv alfa lanca izvanstanične domene il7 receptora i njihova uporaba u liječenju raka
JP2021511818A (ja) Vista抗原結合性分子
WO2017127702A1 (en) Ror2 antibody compositions and related methods
KR20210066865A (ko) 키메라 항원 수용체
US20240018248A1 (en) An ltbr agonist in combination therapy against cancer
JP7584453B2 (ja) Taciを標的とする抗体及びキメラ抗原受容体
JP2025063141A (ja) 抗hK2キメラ抗原受容体(CAR)
US20250026836A1 (en) Anti-hla-g antibodies
JP2025170264A (ja) 抗bcma剤のための投与レジメン
WO2022117569A1 (en) A ccr8 antagonist antibody in combination with a lymphotoxin beta receptor agonist antibody in therapy against cancer
TW202233682A (zh) 用於投與BCMAxCD3結合分子之方法
KR102760955B1 (ko) Gucy2c 결합 폴리펩타이드 및 그의 용도
JP7813235B2 (ja) NPM1c陽性がんの免疫療法のための組成物および方法
KR102290335B1 (ko) Cd30을 표적으로 하는 키메라 항원 수용체 및 이의 용도
CN118382455A (zh) Her2变体car
TWI917473B (zh) Bcma/taci抗原結合分子
Li et al. YMN-V115: a novel humanized BCMA/GPRC5D/CD3 trispecific antibody in relapsed/refractory multiple myeloma
CN117377687A (zh) 抗癌组合疗法中的ltbr激动剂
HK40101561A (zh) 人ccr8结合剂
HK40103081A (zh) 鼠交叉反应性人ccr8结合剂