JP2019513828A - 改善された薬物動態を有するイソフラボノイド組成物 - Google Patents

改善された薬物動態を有するイソフラボノイド組成物 Download PDF

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JP2019513828A
JP2019513828A JP2019503599A JP2019503599A JP2019513828A JP 2019513828 A JP2019513828 A JP 2019513828A JP 2019503599 A JP2019503599 A JP 2019503599A JP 2019503599 A JP2019503599 A JP 2019503599A JP 2019513828 A JP2019513828 A JP 2019513828A
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formula
compound
rectal administration
formulation
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JP2019513828A5 (enExample
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ケリー グレイアム
ケリー グレイアム
ポーター ケイト
ポーター ケイト
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ノクソファーム リミティド
ノクソファーム リミティド
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Priority claimed from PCT/AU2016/050674 external-priority patent/WO2017173474A1/en
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Publication of JP2019513828A5 publication Critical patent/JP2019513828A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/02Suppositories; Bougies; Bases therefor; Ovules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2019503599A 2016-04-06 2017-04-06 改善された薬物動態を有するイソフラボノイド組成物 Ceased JP2019513828A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662318946P 2016-04-06 2016-04-06
US62/318,946 2016-04-06
AUPCT/AU2016/050674 2016-07-28
PCT/AU2016/050674 WO2017173474A1 (en) 2016-04-06 2016-07-28 Improvements in cancer treatment
US201762480692P 2017-04-03 2017-04-03
US62/480,692 2017-04-03
PCT/AU2017/050301 WO2017173498A1 (en) 2016-04-06 2017-04-06 Isoflavonoid composition with improved pharmacokinetics

Publications (2)

Publication Number Publication Date
JP2019513828A true JP2019513828A (ja) 2019-05-30
JP2019513828A5 JP2019513828A5 (enExample) 2020-05-21

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JP2019503599A Ceased JP2019513828A (ja) 2016-04-06 2017-04-06 改善された薬物動態を有するイソフラボノイド組成物

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US (1) US11559510B2 (enExample)
EP (2) EP3439644B1 (enExample)
JP (1) JP2019513828A (enExample)
AU (1) AU2017247008B2 (enExample)
CA (1) CA3058503A1 (enExample)
WO (1) WO2017173498A1 (enExample)

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AU2017247008B2 (en) 2016-04-06 2022-04-07 Noxopharm Limited Isoflavonoid composition with improved pharmacokinetics
WO2021007618A1 (en) * 2019-07-17 2021-01-21 Noxopharm Limited Immuno-oncology therapy using isoflavone compounds
EP4125870A1 (en) 2020-03-30 2023-02-08 Noxopharm Limited Methods for the treatment of inflammation associated with infection

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US11559510B2 (en) 2023-01-24
EP3439644A1 (en) 2019-02-13
US20190117618A1 (en) 2019-04-25
AU2017247008B2 (en) 2022-04-07
EP4005567A1 (en) 2022-06-01
AU2017247008A1 (en) 2018-11-01
EP3439644A4 (en) 2019-10-30
EP3439644B1 (en) 2022-01-12
CA3058503A1 (en) 2017-10-12
WO2017173498A1 (en) 2017-10-12

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