AU2017247008B2 - Isoflavonoid composition with improved pharmacokinetics - Google Patents

Isoflavonoid composition with improved pharmacokinetics Download PDF

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Publication number
AU2017247008B2
AU2017247008B2 AU2017247008A AU2017247008A AU2017247008B2 AU 2017247008 B2 AU2017247008 B2 AU 2017247008B2 AU 2017247008 A AU2017247008 A AU 2017247008A AU 2017247008 A AU2017247008 A AU 2017247008A AU 2017247008 B2 AU2017247008 B2 AU 2017247008B2
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AU
Australia
Prior art keywords
formula
compound
hours
administration
rectal administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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AU2017247008A
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English (en)
Other versions
AU2017247008A1 (en
Inventor
Graham Kelly
Kate PORTER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Noxopharm Ltd
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Noxopharm Ltd
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Filing date
Publication date
Priority claimed from PCT/AU2016/050674 external-priority patent/WO2017173474A1/en
Application filed by Noxopharm Ltd filed Critical Noxopharm Ltd
Publication of AU2017247008A1 publication Critical patent/AU2017247008A1/en
Application granted granted Critical
Publication of AU2017247008B2 publication Critical patent/AU2017247008B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2017247008A 2016-04-06 2017-04-06 Isoflavonoid composition with improved pharmacokinetics Ceased AU2017247008B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662318946P 2016-04-06 2016-04-06
US62/318,946 2016-04-06
PCT/AU2016/050674 WO2017173474A1 (en) 2016-04-06 2016-07-28 Improvements in cancer treatment
AUPCT/AU2016/050674 2016-07-28
US201762480692P 2017-04-03 2017-04-03
US62/480,692 2017-04-03
PCT/AU2017/050301 WO2017173498A1 (en) 2016-04-06 2017-04-06 Isoflavonoid composition with improved pharmacokinetics

Publications (2)

Publication Number Publication Date
AU2017247008A1 AU2017247008A1 (en) 2018-11-01
AU2017247008B2 true AU2017247008B2 (en) 2022-04-07

Family

ID=60000544

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017247008A Ceased AU2017247008B2 (en) 2016-04-06 2017-04-06 Isoflavonoid composition with improved pharmacokinetics

Country Status (6)

Country Link
US (1) US11559510B2 (enExample)
EP (2) EP3439644B1 (enExample)
JP (1) JP2019513828A (enExample)
AU (1) AU2017247008B2 (enExample)
CA (1) CA3058503A1 (enExample)
WO (1) WO2017173498A1 (enExample)

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CA3058503A1 (en) 2016-04-06 2017-10-12 Noxopharm Limited Isoflavonoid composition with improved pharmacokinetics
CA3058492A1 (en) * 2016-04-06 2017-10-12 Noxopharm Limited Radiotherapy improvements
AU2020313090A1 (en) * 2019-07-17 2021-12-23 Noxopharm Limited Immuno-oncology therapy using isoflavone compounds
EP4125870A1 (en) 2020-03-30 2023-02-08 Noxopharm Limited Methods for the treatment of inflammation associated with infection

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Also Published As

Publication number Publication date
EP4005567A1 (en) 2022-06-01
EP3439644A4 (en) 2019-10-30
JP2019513828A (ja) 2019-05-30
AU2017247008A1 (en) 2018-11-01
EP3439644B1 (en) 2022-01-12
US11559510B2 (en) 2023-01-24
US20190117618A1 (en) 2019-04-25
CA3058503A1 (en) 2017-10-12
EP3439644A1 (en) 2019-02-13
WO2017173498A1 (en) 2017-10-12

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