JP2019513775A5 - - Google Patents
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- Publication number
- JP2019513775A5 JP2019513775A5 JP2018553445A JP2018553445A JP2019513775A5 JP 2019513775 A5 JP2019513775 A5 JP 2019513775A5 JP 2018553445 A JP2018553445 A JP 2018553445A JP 2018553445 A JP2018553445 A JP 2018553445A JP 2019513775 A5 JP2019513775 A5 JP 2019513775A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- selenium
- amino acid
- containing amino
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 34
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims 9
- 235000001014 amino acid Nutrition 0.000 claims 9
- 150000001413 amino acids Chemical class 0.000 claims 9
- 229910052711 selenium Inorganic materials 0.000 claims 9
- 239000011669 selenium Substances 0.000 claims 9
- 150000003839 salts Chemical class 0.000 claims 8
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims 5
- FDKWRPBBCBCIGA-REOHCLBHSA-N (2r)-2-azaniumyl-3-$l^{1}-selanylpropanoate Chemical compound [Se]C[C@H](N)C(O)=O FDKWRPBBCBCIGA-REOHCLBHSA-N 0.000 claims 4
- RJFAYQIBOAGBLC-UHFFFAOYSA-N 2-amino-4-methylselanyl-butanoic acid Chemical compound C[Se]CCC(N)C(O)=O RJFAYQIBOAGBLC-UHFFFAOYSA-N 0.000 claims 4
- 238000011200 topical administration Methods 0.000 claims 4
- 206010020649 Hyperkeratosis Diseases 0.000 claims 3
- 208000001126 Keratosis Diseases 0.000 claims 3
- 210000000744 eyelid Anatomy 0.000 claims 3
- 230000000699 topical effect Effects 0.000 claims 3
- 206010065062 Meibomian gland dysfunction Diseases 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 1
- 239000004342 Benzoyl peroxide Substances 0.000 claims 1
- OMPJBNCRMGITSC-UHFFFAOYSA-N Benzoylperoxide Chemical compound C=1C=CC=CC=1C(=O)OOC(=O)C1=CC=CC=C1 OMPJBNCRMGITSC-UHFFFAOYSA-N 0.000 claims 1
- 208000003556 Dry Eye Syndromes Diseases 0.000 claims 1
- 206010013774 Dry eye Diseases 0.000 claims 1
- 229940124091 Keratolytic Drugs 0.000 claims 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 claims 1
- 229940061720 alpha hydroxy acid Drugs 0.000 claims 1
- 150000001280 alpha hydroxy acids Chemical class 0.000 claims 1
- 235000019400 benzoyl peroxide Nutrition 0.000 claims 1
- 239000004202 carbamide Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000011280 coal tar Substances 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- -1 ditranol Chemical compound 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 230000001530 keratinolytic effect Effects 0.000 claims 1
- 239000003410 keratolytic agent Substances 0.000 claims 1
- 235000014655 lactic acid Nutrition 0.000 claims 1
- 239000004310 lactic acid Substances 0.000 claims 1
- 229960000448 lactic acid Drugs 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims 1
- 229920001296 polysiloxane Polymers 0.000 claims 1
- 229930002330 retinoic acid Natural products 0.000 claims 1
- 229960004889 salicylic acid Drugs 0.000 claims 1
- 229910000338 selenium disulfide Inorganic materials 0.000 claims 1
- JNMWHTHYDQTDQZ-UHFFFAOYSA-N selenium sulfide Chemical compound S=[Se]=S JNMWHTHYDQTDQZ-UHFFFAOYSA-N 0.000 claims 1
- 229960005265 selenium sulfide Drugs 0.000 claims 1
- 229960001727 tretinoin Drugs 0.000 claims 1
- 229940045136 urea Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662324795P | 2016-04-19 | 2016-04-19 | |
| US62/324,795 | 2016-04-19 | ||
| PCT/IB2017/000638 WO2017182885A2 (en) | 2016-04-19 | 2017-04-18 | Compositions for the treatment of hyperkeratosis disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019513775A JP2019513775A (ja) | 2019-05-30 |
| JP2019513775A5 true JP2019513775A5 (https=) | 2020-06-18 |
Family
ID=60115757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018553445A Pending JP2019513775A (ja) | 2016-04-19 | 2017-04-18 | 角化症の処置のための組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20200179305A1 (https=) |
| EP (1) | EP3445352A4 (https=) |
| JP (1) | JP2019513775A (https=) |
| KR (1) | KR20180133913A (https=) |
| CN (1) | CN109328061A (https=) |
| AU (1) | AU2017252026A1 (https=) |
| CA (1) | CA3020713A1 (https=) |
| IL (1) | IL262348A (https=) |
| MA (1) | MA44737A (https=) |
| WO (1) | WO2017182885A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9463201B2 (en) | 2014-10-19 | 2016-10-11 | M.G. Therapeutics Ltd | Compositions and methods for the treatment of meibomian gland dysfunction |
| ES3007759T3 (en) * | 2015-09-28 | 2025-03-20 | Azura Ophthalmics Ltd | Thiol and disulfide-containing agents for increasing meibomian gland lipid secretion |
| CN114469991A (zh) | 2016-04-14 | 2022-05-13 | 阿祖拉眼科有限公司 | 用于治疗睑板腺功能障碍的二硫化硒组合物 |
| JP7547048B2 (ja) | 2016-10-12 | 2024-09-09 | ボナファイド・ヘルス，エルエルシー | ピコリン酸マグネシウム組成物および使用方法 |
| CN108840904B (zh) * | 2018-07-12 | 2022-03-04 | 江西中科硒谷功能农业发展有限公司 | 一种从烟叶中提取硒蛋白质的方法 |
| JP7142286B2 (ja) * | 2018-07-13 | 2022-09-27 | 慶應義塾 | セレン含有アミノ酸を含む糖鎖－ポリペプチド複合体、および、その医薬用途 |
| KR20220003555A (ko) | 2019-04-18 | 2022-01-10 | 아주라 오프탈믹스 엘티디 | 안구 장애의 치료를 위한 화합물 및 방법 |
| AU2020259997B2 (en) | 2019-04-18 | 2025-08-07 | Azura Ophthalmics Ltd. | Compounds and methods for the treatment of ocular disorders |
| WO2020212755A1 (en) * | 2019-04-18 | 2020-10-22 | Azura Ophthalmics Ltd. | Compounds and methods for the treatment of ocular disorders |
| WO2020223707A1 (en) * | 2019-05-01 | 2020-11-05 | Nutrition 21, Llc | Zinc picolinate, magnesium picolinate and selenium methionine compositions and methods of use |
| CA3166357A1 (en) | 2020-01-10 | 2021-07-15 | Azura Ophthalmics Ltd. | Instructions for composition and sensitivity |
| KR20230110516A (ko) * | 2020-10-21 | 2023-07-24 | 아주라 오프탈믹스 엘티디 | 눈 장애의 치료를 위한 화합물 및 방법 |
| US11459351B1 (en) | 2021-04-05 | 2022-10-04 | Azura Ophthalmics Ltd. | Compounds and methods for the treatment of ocular disorders |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6011067A (en) * | 1999-06-11 | 2000-01-04 | Thione International, Inc. | Antioxidant composition for the treatment of psoriasis and related diseases |
| US6495158B1 (en) * | 2001-01-19 | 2002-12-17 | Lec Tec Corporation | Acne patch |
| US20020127256A1 (en) * | 2001-03-01 | 2002-09-12 | Howard Murad | Compositions and methods for treating dermatological disorders |
| US20030224028A1 (en) * | 2002-05-13 | 2003-12-04 | Societe L'oreal S.A. | Metal complexes for promoting skin desquamation and/or stimulating epidermal renewal |
| US20050065091A1 (en) * | 2003-09-18 | 2005-03-24 | Gholam Peyman | Stabilized ocular solutions |
| CN1942178A (zh) * | 2004-02-19 | 2007-04-04 | 奥克塞尔公司 | 用于治疗皮肤疾病的局部制剂 |
| ES2422893T3 (es) * | 2004-08-02 | 2013-09-16 | Sami Labs Limited | Composiciones y procedimientos para el tratamiento de las afecciones dermatológicas hiperproliferativas |
| US7776915B2 (en) * | 2005-03-24 | 2010-08-17 | Tracie Martyn International, Llc | Topical formulations and methods of use |
| KR20080031195A (ko) * | 2005-06-22 | 2008-04-08 | 교와 가부시키가이샤 | 각결막 질환의 예방 또는 치료제 |
| WO2011044563A2 (en) * | 2009-10-10 | 2011-04-14 | The Board Of Trustees Of The Leland Stanford Junior University | Il-17 family cytokine compositions and uses |
| US8765725B2 (en) * | 2012-05-08 | 2014-07-01 | Aciex Therapeutics, Inc. | Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof |
| CN105025906B (zh) * | 2012-12-21 | 2020-08-25 | 阿克生物科技公司 | 来自鱼孵化液的化妆品组合物 |
| US9463201B2 (en) * | 2014-10-19 | 2016-10-11 | M.G. Therapeutics Ltd | Compositions and methods for the treatment of meibomian gland dysfunction |
-
2017
- 2017-04-18 US US16/093,616 patent/US20200179305A1/en not_active Abandoned
- 2017-04-18 CA CA3020713A patent/CA3020713A1/en not_active Abandoned
- 2017-04-18 AU AU2017252026A patent/AU2017252026A1/en not_active Abandoned
- 2017-04-18 WO PCT/IB2017/000638 patent/WO2017182885A2/en not_active Ceased
- 2017-04-18 EP EP17785520.2A patent/EP3445352A4/en not_active Withdrawn
- 2017-04-18 MA MA044737A patent/MA44737A/fr unknown
- 2017-04-18 KR KR1020187033299A patent/KR20180133913A/ko not_active Ceased
- 2017-04-18 JP JP2018553445A patent/JP2019513775A/ja active Pending
- 2017-04-18 CN CN201780038116.6A patent/CN109328061A/zh active Pending
-
2018
- 2018-10-14 IL IL262348A patent/IL262348A/en unknown
-
2022
- 2022-04-20 US US17/725,320 patent/US20230013824A1/en not_active Abandoned
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