JP2019513692A5 - - Google Patents
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- JP2019513692A5 JP2019513692A5 JP2018543636A JP2018543636A JP2019513692A5 JP 2019513692 A5 JP2019513692 A5 JP 2019513692A5 JP 2018543636 A JP2018543636 A JP 2018543636A JP 2018543636 A JP2018543636 A JP 2018543636A JP 2019513692 A5 JP2019513692 A5 JP 2019513692A5
- Authority
- JP
- Japan
- Prior art keywords
- monomer
- terminal arm
- conjugated
- terminal
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022078004A JP7516459B2 (ja) | 2016-02-19 | 2022-05-11 | 核酸キャリア及び治療上の使用方法 |
| JP2024067893A JP2024099661A (ja) | 2016-02-19 | 2024-04-19 | 核酸キャリア及び治療上の使用方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662297200P | 2016-02-19 | 2016-02-19 | |
| US62/297,200 | 2016-02-19 | ||
| PCT/US2017/018343 WO2017143171A1 (en) | 2016-02-19 | 2017-02-17 | Nucleic acid carriers and therapeutic methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022078004A Division JP7516459B2 (ja) | 2016-02-19 | 2022-05-11 | 核酸キャリア及び治療上の使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019513692A JP2019513692A (ja) | 2019-05-30 |
| JP2019513692A5 true JP2019513692A5 (https=) | 2020-03-12 |
Family
ID=59626355
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018543636A Pending JP2019513692A (ja) | 2016-02-19 | 2017-02-17 | 核酸キャリア及び治療上の使用方法 |
| JP2022078004A Active JP7516459B2 (ja) | 2016-02-19 | 2022-05-11 | 核酸キャリア及び治療上の使用方法 |
| JP2024067893A Pending JP2024099661A (ja) | 2016-02-19 | 2024-04-19 | 核酸キャリア及び治療上の使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022078004A Active JP7516459B2 (ja) | 2016-02-19 | 2022-05-11 | 核酸キャリア及び治療上の使用方法 |
| JP2024067893A Pending JP2024099661A (ja) | 2016-02-19 | 2024-04-19 | 核酸キャリア及び治療上の使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US12076410B2 (https=) |
| EP (1) | EP3416691A4 (https=) |
| JP (3) | JP2019513692A (https=) |
| AU (2) | AU2017221437A1 (https=) |
| WO (1) | WO2017143171A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3416671A4 (en) | 2016-02-19 | 2019-10-30 | Genisphere, LLC | NUCLEIC ACID CARRIER AND THERAPEUTIC METHODS OF USE |
| JP6871948B2 (ja) | 2016-04-27 | 2021-05-19 | アッヴィ・インコーポレイテッド | 抗ｉｌ−１３抗体を使用する、ｉｌ−１３活性が有害である疾患の治療方法 |
| MX2019012295A (es) | 2017-04-14 | 2020-02-07 | Tollnine Inc | Polinucleotidos inmunomoduladores, conjugados de anticuerpos de los mismos y metodos para su uso. |
| IL271386B2 (en) | 2017-06-16 | 2025-02-01 | Univ Duke | Enhanced resonator networks for label detection, computation, analyte sensing, and tunable random number generation |
| US20190269728A1 (en) | 2018-03-02 | 2019-09-05 | Sixfold Bioscience Ltd. | Compositions for delivery of cargo to cells |
| US20190284553A1 (en) | 2018-03-15 | 2019-09-19 | KSQ Therapeutics, Inc. | Gene-regulating compositions and methods for improved immunotherapy |
| JP7536025B2 (ja) * | 2018-10-17 | 2024-08-19 | タラック セラピューティクス，インク． | 免疫調節性ポリヌクレオチドコンジュゲートと使用方法 |
| CN110092826B (zh) * | 2019-02-28 | 2022-04-15 | 天津大学 | CTLA-4类似物CFN13及CFN13-Fc基因和蛋白 |
| WO2020200481A1 (en) * | 2019-04-05 | 2020-10-08 | Biontech Rna Pharmaceuticals Gmbh | Treatment involving interleukin-2 (il2) and interferon (ifn) |
| WO2021053405A2 (en) | 2019-08-30 | 2021-03-25 | Sixfold Bioscience Ltd. | Compositions for transfer of cargo to cells |
| US11802151B2 (en) | 2019-11-04 | 2023-10-31 | Code Biotherapeutics, Inc. | Brain-specific angiogenesis inhibitor 1 (BAI1) antibodies and uses thereof |
| CA3169523A1 (en) | 2020-02-28 | 2021-09-02 | Jaume Pons | Transglutaminase-mediated conjugation |
| CN115997016A (zh) | 2020-04-27 | 2023-04-21 | 西克斯福德生物科学有限公司 | 包含具有模块化官能团的核酸纳米颗粒的组合物 |
| WO2025038373A1 (en) * | 2023-08-11 | 2025-02-20 | Unm Rainforest Innovations | Compositions and methods targeting osteoactivin |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL112920A (en) * | 1994-03-07 | 2003-04-10 | Dow Chemical Co | Composition comprising a dendritic polymer complexed with at least one unit of biological response modifier and a process for the preparation thereof |
| WO1999006595A1 (en) * | 1997-07-29 | 1999-02-11 | Polyprobe, Inc. | Dendritic nucleic acids exhibiting maximal self-assembly |
| US6287765B1 (en) | 1998-05-20 | 2001-09-11 | Molecular Machines, Inc. | Methods for detecting and identifying single molecules |
| EP2423335B1 (en) | 2001-06-21 | 2014-05-14 | Dynavax Technologies Corporation | Chimeric immunomodulatory compounds and methods of using the same |
| EP1530581A4 (en) | 2002-06-12 | 2006-08-30 | Datascope Investment Corp | POLYMERIC MARKING MOLECULES |
| CN1753687A (zh) * | 2002-10-29 | 2006-03-29 | 科勒制药集团股份有限公司 | Cpg寡核苷酸在治疗丙型肝炎病毒感染中的应用 |
| CA2502015A1 (en) | 2002-12-11 | 2004-06-24 | Coley Pharmaceutical Group, Inc. | 5' cpg nucleic acids and methods of use |
| US20100136614A1 (en) | 2005-10-18 | 2010-06-03 | Dan Luo | Dendrimer-like modular delivery vector |
| WO2008144562A1 (en) | 2007-05-16 | 2008-11-27 | California Institute Of Technology | A versatile nucleic acid hairpin motif for programming biomolecular self-assembly pathways |
| WO2008147526A1 (en) | 2007-05-23 | 2008-12-04 | The Trustees Of The University Of Pennsylvania | Targeted carriers for intracellular drug delivery |
| RU2010107199A (ru) | 2007-07-31 | 2011-09-10 | Дзе Джонс Хопкинс Юниверсити (Us) | Конъюгат полипептид-нуклеиновая кислота для иммунопрофилактики или иммунотерапии для неопластических или инфекционных нарушений |
| US20120122800A1 (en) * | 2008-08-08 | 2012-05-17 | Genisphere, LLC Hatfield, Pennsylvania | Long-Acting DNA Dendrimers and Methods Thereof |
| US20110206611A1 (en) | 2010-02-24 | 2011-08-25 | Genisphere, Llc | DNA Dendrimers as Thermal Ablation Devices |
| WO2011115810A2 (en) * | 2010-03-16 | 2011-09-22 | Massachusetts Institute Of Technology | Isoform-specific rnai based on codon redundancy/degeneracy |
| WO2012125987A2 (en) | 2011-03-17 | 2012-09-20 | Massachusetts Institute Of Technology | Delivery system |
| WO2014001326A1 (en) | 2012-06-27 | 2014-01-03 | F. Hoffmann-La Roche Ag | Method for the selection and production of tailor-made, selective and multi-specific therapeutic molecules comprising at least two different targeting entities and uses thereof |
| US9651549B2 (en) | 2012-07-13 | 2017-05-16 | Genisphere, Llc | Lateral flow assays using DNA dendrimers |
| JP2015536952A (ja) * | 2012-11-05 | 2015-12-24 | プロナイ セラピューティクス インコーポレイテッド | オリゴヌクレオチド癌療法の投薬および実施 |
| EP2950825B1 (en) | 2013-02-01 | 2019-09-11 | Genisphere, LLC | Functionalized dna dendrimers for gene delivery to cells |
| US20160051693A1 (en) * | 2013-03-21 | 2016-02-25 | Genisphere, Llc | Cellular Delivery of DNA Intercalating Agents |
| AU2014357292B2 (en) | 2013-11-27 | 2020-06-25 | Zymeworks Bc Inc. | Bispecific antigen-binding constructs targeting HER2 |
| EP3289084B1 (en) * | 2015-04-17 | 2020-09-16 | Genisphere, LLC | siRNA INHIBITION OF HUMAN ANTIGEN R EXPRESSION FOR TREATMENT OF CANCER |
| EP3416671A4 (en) * | 2016-02-19 | 2019-10-30 | Genisphere, LLC | NUCLEIC ACID CARRIER AND THERAPEUTIC METHODS OF USE |
-
2017
- 2017-02-17 AU AU2017221437A patent/AU2017221437A1/en not_active Abandoned
- 2017-02-17 EP EP17753912.9A patent/EP3416691A4/en active Pending
- 2017-02-17 WO PCT/US2017/018343 patent/WO2017143171A1/en not_active Ceased
- 2017-02-17 US US15/999,781 patent/US12076410B2/en active Active
- 2017-02-17 JP JP2018543636A patent/JP2019513692A/ja active Pending
-
2022
- 2022-05-11 JP JP2022078004A patent/JP7516459B2/ja active Active
-
2024
- 2024-04-19 JP JP2024067893A patent/JP2024099661A/ja active Pending
- 2024-04-29 AU AU2024202764A patent/AU2024202764B2/en active Active
- 2024-07-24 US US18/782,174 patent/US20250049942A1/en active Pending
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