JP2019513692A5 - - Google Patents
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- JP2019513692A5 JP2019513692A5 JP2018543636A JP2018543636A JP2019513692A5 JP 2019513692 A5 JP2019513692 A5 JP 2019513692A5 JP 2018543636 A JP2018543636 A JP 2018543636A JP 2018543636 A JP2018543636 A JP 2018543636A JP 2019513692 A5 JP2019513692 A5 JP 2019513692A5
- Authority
- JP
- Japan
- Prior art keywords
- monomer
- terminal arm
- conjugated
- terminal
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022078004A JP7516459B2 (ja) | 2016-02-19 | 2022-05-11 | 核酸キャリア及び治療上の使用方法 |
| JP2024067893A JP2024099661A (ja) | 2016-02-19 | 2024-04-19 | 核酸キャリア及び治療上の使用方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662297200P | 2016-02-19 | 2016-02-19 | |
| US62/297,200 | 2016-02-19 | ||
| PCT/US2017/018343 WO2017143171A1 (en) | 2016-02-19 | 2017-02-17 | Nucleic acid carriers and therapeutic methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022078004A Division JP7516459B2 (ja) | 2016-02-19 | 2022-05-11 | 核酸キャリア及び治療上の使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019513692A JP2019513692A (ja) | 2019-05-30 |
| JP2019513692A5 true JP2019513692A5 (OSRAM) | 2020-03-12 |
Family
ID=59626355
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018543636A Pending JP2019513692A (ja) | 2016-02-19 | 2017-02-17 | 核酸キャリア及び治療上の使用方法 |
| JP2022078004A Active JP7516459B2 (ja) | 2016-02-19 | 2022-05-11 | 核酸キャリア及び治療上の使用方法 |
| JP2024067893A Pending JP2024099661A (ja) | 2016-02-19 | 2024-04-19 | 核酸キャリア及び治療上の使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022078004A Active JP7516459B2 (ja) | 2016-02-19 | 2022-05-11 | 核酸キャリア及び治療上の使用方法 |
| JP2024067893A Pending JP2024099661A (ja) | 2016-02-19 | 2024-04-19 | 核酸キャリア及び治療上の使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US12076410B2 (OSRAM) |
| EP (1) | EP3416691A4 (OSRAM) |
| JP (3) | JP2019513692A (OSRAM) |
| AU (2) | AU2017221437A1 (OSRAM) |
| WO (1) | WO2017143171A1 (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL260983B (en) | 2016-02-19 | 2022-07-01 | Genisphere Llc | Nucleic acid carriers and methods of medical use |
| KR20240052871A (ko) | 2016-04-27 | 2024-04-23 | 애브비 인코포레이티드 | 항-il-13 항체를 이용한 il-13 활성이 유해한 질환의 치료 방법 |
| KR102808275B1 (ko) | 2017-04-14 | 2025-05-20 | 탈락 테라퓨틱스, 인크. | 면역조절 폴리뉴클레오티드, 이의 항체 접합체, 및 이의 사용 방법 |
| JP7270254B2 (ja) | 2017-06-16 | 2023-05-10 | デューク ユニバーシティ | 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク |
| EP3759225A1 (en) | 2018-03-02 | 2021-01-06 | Sixfold Bioscience Ltd. | Compositions for delivery of cargo to cells |
| US20190284553A1 (en) | 2018-03-15 | 2019-09-19 | KSQ Therapeutics, Inc. | Gene-regulating compositions and methods for improved immunotherapy |
| BR112021007294A2 (pt) * | 2018-10-17 | 2021-07-27 | Tallac Therapeutics, Inc. | imunomodulação de conjugados de polinucleotídeos e métodos de uso |
| CN110092826B (zh) * | 2019-02-28 | 2022-04-15 | 天津大学 | CTLA-4类似物CFN13及CFN13-Fc基因和蛋白 |
| WO2020200481A1 (en) * | 2019-04-05 | 2020-10-08 | Biontech Rna Pharmaceuticals Gmbh | Treatment involving interleukin-2 (il2) and interferon (ifn) |
| US20230183746A1 (en) | 2019-08-30 | 2023-06-15 | Sixfold Bioscience Ltd. | Compositions for transfer of cargo to cells |
| US11802151B2 (en) | 2019-11-04 | 2023-10-31 | Code Biotherapeutics, Inc. | Brain-specific angiogenesis inhibitor 1 (BAI1) antibodies and uses thereof |
| US11920136B2 (en) | 2020-02-28 | 2024-03-05 | Tallac Therapeutics, Inc. | Transglutaminase-mediated conjugation |
| JP2023523345A (ja) | 2020-04-27 | 2023-06-02 | シックスフォールド バイオサイエンス リミテッド | モジュール官能基を有する核酸ナノ粒子を含有する組成物 |
| WO2025038373A1 (en) * | 2023-08-11 | 2025-02-20 | Unm Rainforest Innovations | Compositions and methods targeting osteoactivin |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE277640T1 (de) * | 1994-03-07 | 2004-10-15 | Dow Chemical Co | Bioaktive und/oder gezielte dendrimere-konjugate enthaltend genetisches material |
| EP1005573B1 (en) * | 1997-07-29 | 2006-05-24 | Polyprobe, Inc. | Dendritic nucleic acids exhibiting maximal self-assembly |
| US6287765B1 (en) | 1998-05-20 | 2001-09-11 | Molecular Machines, Inc. | Methods for detecting and identifying single molecules |
| EP1404873B1 (en) | 2001-06-21 | 2013-05-22 | Dynavax Technologies Corporation | Chimeric immunomodulatory compounds and methods of using the same |
| JP2005529606A (ja) | 2002-06-12 | 2005-10-06 | データスコープ・インベストメント・コーポレイション | ポリマー標識分子 |
| CA2503693A1 (en) * | 2002-10-29 | 2004-05-13 | Coley Pharmaceutical Group, Ltd. | Use of cpg oligonucleotides in the treatment of hepatitis c virus infection |
| JP2006512927A (ja) | 2002-12-11 | 2006-04-20 | コーリー ファーマシューティカル グループ,インコーポレイテッド | 5’cpg核酸およびその使用方法 |
| US20100136614A1 (en) | 2005-10-18 | 2010-06-03 | Dan Luo | Dendrimer-like modular delivery vector |
| US9217151B2 (en) | 2007-05-16 | 2015-12-22 | California Institute Of Technology | Versatile nucleic acid hairpin motif for programming biomolecular self-assembly pathways |
| WO2008147526A1 (en) | 2007-05-23 | 2008-12-04 | The Trustees Of The University Of Pennsylvania | Targeted carriers for intracellular drug delivery |
| CA2695385A1 (en) | 2007-07-31 | 2009-02-05 | Atul Bedi | Polypeptide-nucleic acid conjugate for immunoprophylaxis or immunotherapy for neoplastic or infectious disorders |
| WO2010017544A2 (en) | 2008-08-08 | 2010-02-11 | Genisphere, Inc. | Long-acting dna dendrimers and methods thereof |
| US20110206611A1 (en) | 2010-02-24 | 2011-08-25 | Genisphere, Llc | DNA Dendrimers as Thermal Ablation Devices |
| US20130018086A1 (en) * | 2010-03-16 | 2013-01-17 | Massachusette Institute Of Technology | Sirnas targeting exon 10 of pyruvate kinase m2 |
| WO2012125987A2 (en) | 2011-03-17 | 2012-09-20 | Massachusetts Institute Of Technology | Delivery system |
| EP2867255B1 (en) | 2012-06-27 | 2017-07-19 | F. Hoffmann-La Roche AG | Method for the selection and production of tailor-made, selective and multi-specific therapeutic molecules comprising at least two different targeting entities and uses thereof |
| US9651549B2 (en) * | 2012-07-13 | 2017-05-16 | Genisphere, Llc | Lateral flow assays using DNA dendrimers |
| KR20150086294A (ko) * | 2012-11-05 | 2015-07-27 | 프로나이 테라퓨틱스, 인코포레이티드 | 올리고뉴클레오티드 암 치료제의 복용 및 투여 |
| JP2016513089A (ja) | 2013-02-01 | 2016-05-12 | ジェニスフィア・エルエルシー | 細胞への遺伝子送達のための機能性dnaデンドリマー |
| US20160051693A1 (en) * | 2013-03-21 | 2016-02-25 | Genisphere, Llc | Cellular Delivery of DNA Intercalating Agents |
| EP4570318A3 (en) | 2013-11-27 | 2025-10-15 | Zymeworks BC Inc. | Bispecific antigen-binding constructs targeting her2 |
| WO2016168578A1 (en) | 2015-04-17 | 2016-10-20 | Genisphere, Llc | siRNA INHIBITION OF HUMAN ANTIGEN R EXPRESSION FOR TREATMENT OF CANCER |
| IL260983B (en) * | 2016-02-19 | 2022-07-01 | Genisphere Llc | Nucleic acid carriers and methods of medical use |
-
2017
- 2017-02-17 JP JP2018543636A patent/JP2019513692A/ja active Pending
- 2017-02-17 AU AU2017221437A patent/AU2017221437A1/en not_active Abandoned
- 2017-02-17 EP EP17753912.9A patent/EP3416691A4/en active Pending
- 2017-02-17 US US15/999,781 patent/US12076410B2/en active Active
- 2017-02-17 WO PCT/US2017/018343 patent/WO2017143171A1/en not_active Ceased
-
2022
- 2022-05-11 JP JP2022078004A patent/JP7516459B2/ja active Active
-
2024
- 2024-04-19 JP JP2024067893A patent/JP2024099661A/ja active Pending
- 2024-04-29 AU AU2024202764A patent/AU2024202764B2/en active Active
- 2024-07-24 US US18/782,174 patent/US20250049942A1/en active Pending
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