JP2019511519A - 10−ヒドロキシステアリン酸組成物 - Google Patents
10−ヒドロキシステアリン酸組成物 Download PDFInfo
- Publication number
- JP2019511519A JP2019511519A JP2018553091A JP2018553091A JP2019511519A JP 2019511519 A JP2019511519 A JP 2019511519A JP 2018553091 A JP2018553091 A JP 2018553091A JP 2018553091 A JP2018553091 A JP 2018553091A JP 2019511519 A JP2019511519 A JP 2019511519A
- Authority
- JP
- Japan
- Prior art keywords
- weight
- topical composition
- acid
- range
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/062—Oil-in-water emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/604—Alkylpolyglycosides; Derivatives thereof, e.g. esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/608—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/49—Solubiliser, Solubilising system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
【選択図】なし
Description
両方のエナンチオマーが本発明に従って使用され得、好ましいエナンチオマー形態は、(R)−10−ヒドロキシステアリン酸である。
異なる乳化剤(アニオン性(基準)及び非イオン性(本発明))を使用する種々の製剤を、表1及び2に略記された通りに調製した。最初に、製剤のいずれにも顕微鏡分析により結晶は全く観察されなかった。次いで、製剤を室温で保存し、10−ヒドロキシステアリン酸の再結晶化に関して3か月まで繰り返し顕微鏡で分析した。その結果を表2に略記する。
第1に、パートAを90℃に、パートBを80℃に加熱する。
第2に、パートAとパートBとを合わせ、1分間10.000rpmで均質化する。
第3に、撹拌しながら冷却する。
第4に、撹拌しながらパートCを35℃で加える。
第5に、最後に撹拌しながら室温に冷却する。
表3に列記した非イオン性のPEG系乳化剤(ステアリン酸PEG−40)及びアニオン性乳化剤(ステアリン酸)を含む製剤を調製した。
Claims (16)
- イソブチルパラベンを含まないことを条件として、10−ヒドロキシステアリン酸又はその塩及び少なくとも1種の非イオン性乳化剤を含む局所組成物。
- 冷感剤及び/又は発熱剤も含まない、請求項1に記載の局所組成物。
- 前記10−ヒドロキシステアリン酸又はその塩の量は、前記組成物の総重量に基づいて0.001〜5重量%の範囲、好ましくは0.01〜3重量%の範囲、最も好ましくは0.1〜2重量%の範囲、例えば特に0.1〜1.5重量%の範囲で選択されることを特徴とする、請求項1又は2に記載の局所組成物。
- 前記非イオン性乳化剤の量は、前記組成物の前記総重量に基づいて0.1〜7重量%の範囲、好ましくは1〜6重量%の範囲、最も好ましくは1〜5重量%の範囲で選択されることを特徴とする、請求項1〜3のいずれか一項に記載の局所組成物。
- 10−ヒドロキシステアリン酸、特に(R)−10−ヒドロキシステアリン酸が使用されることを特徴とする、請求項1〜4のいずれか一項に記載の局所組成物。
- 前記少なくとも1種の非イオン性乳化剤は、脂肪族アルコールのエステル、ポリアルキレングリコールアルキルエーテル、ポリアルキレングリコール脂肪酸エステル、グルコシドアルキルエーテル、アルキルグルコースエステル、グリセロールアルキルエステル、ソルビタン脂肪酸エステル、及びポリエチレングリコールとポリプロピレングリコールとのブロックポリマーからなる群から選択されることを特徴とする、請求項1〜5のいずれか一項に記載の局所組成物。
- 前記少なくとも1種の非イオン性乳化剤は、C12〜C22−アルコールのC12〜C22−アルキルエステル、ポリエチレングリコールアルキルエーテル、例えば、より好ましくは2〜30のエチレンオキシド数を有するポリエチレングリコールC12〜C22−アルキルエーテル、ポリエチレングリコール脂肪酸エステル、例えば、より好ましくは2〜150のエチレンオキシド数を有するポリエチレングリコールC12〜C22脂肪酸エステル、(ポリグリセリル)アルキルグルコースアルキルエステル、グリセロールC12〜C22脂肪酸エステル及びソルビタンモノ脂肪酸エステルからなる群から選択されることを特徴とする、請求項1〜6のいずれか一項に記載の局所組成物。
- 前記少なくとも1種の非イオン性乳化剤は、ジステアリン酸ポリグリセリ−3メチルグルコース、セテアリルグルコシド、セスキステアリン酸メチルグルコース、オリーブ油脂肪酸セテアリル、オリーブ油脂肪酸ソルビタン、ステアリン酸PEG−40、ステアリン酸PEG−100、ステアリン酸グリセリル、ステアレス−2及びステアレス−21からなる群から選択されることを特徴とする、請求項1〜7のいずれか一項に記載の局所組成物。
- 12〜22個の炭素原子を有する非イオン性固体脂肪族アルコール及びそれらの混合物の群から、好ましくはセチルアルコール、ベヘニルアルコール及びセテアリルアルコール並びにそれらの混合物から選択される共乳化剤を含むことを特徴とする、請求項1〜8のいずれか一項に記載の局所組成物。
- 共乳化剤の量は、前記組成物の前記総重量に基づいて0.1〜20重量%の範囲、より好ましくは0.5〜10重量%の範囲、最も好ましくは前記組成物の前記総重量に基づいて1〜5重量%の範囲で選択されることを特徴とする、請求項1〜9のいずれか一項に記載の局所組成物。
- フェノキシエタノール及びエチルヘキシルグリセリン並びにそれらの混合物からなる群から選択される保存剤を含むことを特徴とする、請求項1〜10のいずれか一項に記載の局所組成物。
- 水相及び油相を含むO/Wエマルションであることを特徴とする、請求項1〜11のいずれか一項に記載の局所組成物。
- 前記組成物の前記総重量に基づいて、前記水相は、少なくとも50重量%を構成し、及び前記油相は、少なくとも10重量%を構成することを特徴とする、請求項12に記載の局所組成物。
- 局所組成物中の10−ヒドロキシステアリン酸又はその塩の再結晶化を抑制又は阻止する方法であって、10−ヒドロキシステアリン酸又はその塩を少なくとも1種の非イオン性乳化剤の存在下で製剤することを含む方法。
- 前記少なくとも1種の非イオン性乳化剤は、ジステアリン酸ポリグリセリ−3メチルグルコース、セテアリルグルコシド、オリーブ油脂肪酸セテアリル、オリーブ油脂肪酸ソルビタン、セスキステアリン酸メチルグルコース、ステアリン酸PEG−40、ステアリン酸PEG−100、ステアリン酸グリセリル、ステアレス−2及びステアレス−21並びにそれらの混合物からなる群から選択されることを特徴とする、請求項14に記載の方法。
- 前記少なくとも1種の非イオン性乳化剤は、ステアリン酸PEG−40、ステアリン酸PEG−100、ステアレス−2及びステアレス−21並びにそれらの混合物からなる群から選択されることを特徴とする、請求項15に記載の方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16164998 | 2016-04-13 | ||
EP16164998.3 | 2016-04-13 | ||
PCT/EP2017/057423 WO2017178235A1 (en) | 2016-04-13 | 2017-03-29 | 10-hydroxystearic acid compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2019511519A true JP2019511519A (ja) | 2019-04-25 |
JP6923267B2 JP6923267B2 (ja) | 2021-08-18 |
Family
ID=55745685
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2018553091A Active JP6923267B2 (ja) | 2016-04-13 | 2017-03-29 | 10−ヒドロキシステアリン酸組成物 |
Country Status (8)
Country | Link |
---|---|
US (1) | US10786453B2 (ja) |
EP (1) | EP3442494B1 (ja) |
JP (1) | JP6923267B2 (ja) |
KR (1) | KR102369403B1 (ja) |
CN (1) | CN109069381B (ja) |
BR (1) | BR112018071088B1 (ja) |
ES (1) | ES2924126T3 (ja) |
WO (1) | WO2017178235A1 (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102019110921A1 (de) * | 2019-04-26 | 2020-10-29 | Fuchs Petrolub Se | Schmierfette umfassend Metallseifen und Metallkomplexseifen auf Basis von R-10-Hydroxyoctadecansäure |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6190680B1 (en) * | 1998-04-01 | 2001-02-20 | The Nisshin Oil Mills, Ltd. | Oily composition and process for producing the same |
US6680285B2 (en) * | 2000-12-21 | 2004-01-20 | Unilever Home & Personal Care Usa A Division Of Conopco, Inc. | Skin cleansing bar with high levels of liquid emollient |
GB0202853D0 (en) | 2002-02-07 | 2002-03-27 | Dow Corning | Encapsulation process and encapsulated compositions |
JP2004250416A (ja) * | 2003-02-17 | 2004-09-09 | Takashi Yokota | 透明性基剤及びそれを配合した化粧料 |
CN101272775B (zh) * | 2005-09-23 | 2012-05-30 | 帝斯曼知识产权资产管理有限公司 | 包含羟基脂肪酸的化妆品组合物 |
JP5312847B2 (ja) * | 2008-05-30 | 2013-10-09 | 株式会社マンダム | 非水系温感皮膚洗浄用組成物 |
US8691301B2 (en) * | 2008-06-30 | 2014-04-08 | Kimberly-Clark Worldwide, Inc. | Surfactant gas pressurized liquid composition and method and package for delivering |
EP2470159A1 (en) * | 2009-08-28 | 2012-07-04 | Mary Kay, Inc. | Skin care formulations |
JP6030067B2 (ja) * | 2010-12-03 | 2016-11-24 | アラーガン、インコーポレイテッドAllergan,Incorporated | 薬学的クリーム組成物および使用法 |
US8613939B2 (en) | 2010-12-15 | 2013-12-24 | Conopco, Inc. | Leave-on nonsolid skin conditioning compositions containing 12-hydroxystearic acid and ethoxylated hydrogenated castor oil |
CN105407861A (zh) * | 2013-08-01 | 2016-03-16 | 莱雅公司 | 包含聚甘油酯、多元醇和表面活性剂的无水组合物 |
KR101556362B1 (ko) * | 2014-05-14 | 2015-10-01 | (주) 인우 코퍼레이션 | 10-하이드록시스테아르산 반응혼합물의 제조 및 분리정제 방법 |
CN107072902B (zh) * | 2014-10-17 | 2021-01-19 | 帝斯曼知识产权资产管理有限公司 | 包含10-羟基硬脂酸的美容组合物的用途 |
-
2017
- 2017-03-29 WO PCT/EP2017/057423 patent/WO2017178235A1/en active Application Filing
- 2017-03-29 KR KR1020187031227A patent/KR102369403B1/ko active IP Right Grant
- 2017-03-29 BR BR112018071088-1A patent/BR112018071088B1/pt not_active IP Right Cessation
- 2017-03-29 CN CN201780023127.7A patent/CN109069381B/zh not_active Expired - Fee Related
- 2017-03-29 JP JP2018553091A patent/JP6923267B2/ja active Active
- 2017-03-29 ES ES17714223T patent/ES2924126T3/es active Active
- 2017-03-29 EP EP17714223.9A patent/EP3442494B1/en active Active
- 2017-03-29 US US16/092,514 patent/US10786453B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
ES2924126T3 (es) | 2022-10-04 |
CN109069381A (zh) | 2018-12-21 |
KR20180129876A (ko) | 2018-12-05 |
BR112018071088A2 (pt) | 2019-02-05 |
US20190160006A1 (en) | 2019-05-30 |
JP6923267B2 (ja) | 2021-08-18 |
EP3442494B1 (en) | 2022-06-15 |
BR112018071088B1 (pt) | 2022-05-03 |
CN109069381B (zh) | 2021-11-30 |
US10786453B2 (en) | 2020-09-29 |
KR102369403B1 (ko) | 2022-03-02 |
WO2017178235A1 (en) | 2017-10-19 |
EP3442494A1 (en) | 2019-02-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0721862B1 (pt) | preparação compreendendo sais solúveis estáveis de ácido fenilbenzimidazol sulfônico, e uso de aminoácidos básicos | |
AU2009248015A1 (en) | Sunscreens | |
WO2010127987A2 (en) | Sunscreens | |
EP2301519A1 (en) | Ultraviolet absorbing composition | |
KR101639457B1 (ko) | 펜타나트륨 (에틸렌다이아민) 테트라메틸렌포스포네이트를 포함하는 화장품 조성물 | |
JP6834086B2 (ja) | 10−ヒドロキシステアリン酸組成物 | |
US7244417B2 (en) | Stabilization of oxidation-sensitive or UV-sensitive active ingredients | |
ES2531631T3 (es) | Composiciones de protección solar | |
CN109069381B (zh) | 10-羟基硬脂酸组合物 | |
CN105120831B (zh) | 包含脂肪酸和非离子线性聚合物的防晒组合物 | |
US20170304171A1 (en) | Alcohol-free emulsion based on nonionic surfactants, on an anionic amphiphilic lipid and on liposoluble organic uv-screening agents | |
JP6155492B2 (ja) | 新規組成物 | |
CN117320687A (zh) | 包含贝莫三嗪醇的防晒组合物 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20200218 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20201223 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20210105 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20210330 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20210629 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20210726 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 6923267 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |