JP2019511483A - 免疫療法のためのｓｔｉｎｇ活性化ナノワクチン - Google Patents

免疫療法のためのｓｔｉｎｇ活性化ナノワクチン Download PDF

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JP2019511483A
JP2019511483A JP2018545910A JP2018545910A JP2019511483A JP 2019511483 A JP2019511483 A JP 2019511483A JP 2018545910 A JP2018545910 A JP 2018545910A JP 2018545910 A JP2018545910 A JP 2018545910A JP 2019511483 A JP2019511483 A JP 2019511483A
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composition
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substituted
cycloalkyl
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JP2019511483A5 (enExample
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ジンミン ガオ
ジンミン ガオ
ジーチアン チェン
ジーチアン チェン
ミン ルオ
ミン ルオ
チャオホイ ワン
チャオホイ ワン
ホワ ワン
ホワ ワン
ハオチェン カイ
ハオチェン カイ
ガン ファン
ガン ファン
ヤン−シン フー
ヤン−シン フー
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University of Texas System
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University of Texas System
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    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
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    • A61K2039/55511—Organic adjuvants
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    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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JP2018545910A 2016-03-02 2017-03-02 免疫療法のためのｓｔｉｎｇ活性化ナノワクチン Pending JP2019511483A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662302637P 2016-03-02 2016-03-02
US62/302,637 2016-03-02
PCT/US2017/020451 WO2017151922A1 (en) 2016-03-02 2017-03-02 Sting activating nanovaccine for immunotherapy

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JP2019511483A true JP2019511483A (ja) 2019-04-25
JP2019511483A5 JP2019511483A5 (enExample) 2020-04-09

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US (1) US11376324B2 (enExample)
EP (1) EP3423044A4 (enExample)
JP (1) JP2019511483A (enExample)
KR (1) KR20180114946A (enExample)
CN (1) CN109069440A (enExample)
AU (1) AU2017225769B2 (enExample)
CA (1) CA3016457A1 (enExample)
MX (1) MX2018010586A (enExample)
WO (1) WO2017151922A1 (enExample)

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JP2022534497A (ja) * 2019-05-28 2022-08-01 ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム ｐＨ応答性組成物およびその使用法
JP2023502998A (ja) * 2019-11-18 2023-01-26 オンコナノ・メディスン・インコーポレイテッド ｐＨ応答性組成物、製剤、及び腫瘍画像化の方法
JP2023546316A (ja) * 2020-09-08 2023-11-02 ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム 多価ｓｔｉｎｇ活性化組成物およびその使用法

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CA3074232A1 (en) 2017-08-31 2019-03-07 Sperovie Biosciences, Inc. Compounds, compositions, and methods for the treatment of disease
WO2019051488A1 (en) 2017-09-11 2019-03-14 Sperovie Biosciences, Inc. COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISEASE
US11707531B2 (en) 2017-09-11 2023-07-25 F-star Therapeutics, Inc. Compounds, compositions, and methods for the treatment of disease
US20210177964A1 (en) * 2017-11-06 2021-06-17 Memorial Sloan Kettering Cancer Center Heat-inactivated vaccinia virus as a vaccine immune adjuvant
TWI818943B (zh) * 2018-01-04 2023-10-21 中央研究院 用於增加療效之可與細胞結合的免疫佐劑
JP7542257B2 (ja) * 2018-01-25 2024-08-30 エイシーエム バイオラブズ プライベート リミテッド 可溶化された封入抗原を含むポリマーソーム、ならびにその作製および使用方法
WO2019147509A1 (en) * 2018-01-26 2019-08-01 The Regents Of The University Of California Intranasal delivery of a cyclic-di-nucleotide adjuvanted vaccine for tuberculosis
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WO2020028566A1 (en) 2018-07-31 2020-02-06 Incyte Corporation Heteroaryl amide compounds as sting activators
WO2020028565A1 (en) 2018-07-31 2020-02-06 Incyte Corporation Tricyclic heteraryl compounds as sting activators
CN109453364B (zh) * 2018-09-30 2021-10-15 郑州大学第一附属医院 一种双重响应性纳米颗粒及其在肿瘤抑制中的应用
US11596692B1 (en) 2018-11-21 2023-03-07 Incyte Corporation PD-L1/STING conjugates and methods of use
WO2020146237A1 (en) 2019-01-07 2020-07-16 Incyte Corporation Heteroaryl amide compounds as sting activators
DK3934757T3 (da) * 2019-03-07 2023-04-17 Inst Of Organic Chemistry And Biochemistry Ascr V V I 2'3'-cykliske dinukleotider og prodrugs deraf
JP7676331B2 (ja) 2019-06-22 2025-05-14 ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム 生分解性超ｐＨ感受性ポリマー
AU2020379482A1 (en) * 2019-11-07 2022-06-23 Samyang Holdings Corporation Polymer nanoparticle composition for inducing immunity and preparation method therefor
GB201918963D0 (en) * 2019-12-20 2020-02-05 Provost Fellows Scholars And Other Members Of Board Of Trinity College Dublin Polymeric nanoparticles as vaccine adjuvants
CN111184738B (zh) * 2020-03-04 2021-05-28 北京大学 一种二嵌段共聚物或其药学上可接受的盐在制备抗病毒药物中的应用、药物组合物
CN113577255B (zh) * 2020-04-30 2023-09-08 中国科学院上海药物研究所 肿瘤纳米疫苗、其制备方法及用途
US20250127921A1 (en) * 2021-08-10 2025-04-24 Wisconsin Alumni Research Foundation Ph-responsive nano particle for delivery of ribonucleoproteins
CN114456331A (zh) * 2022-02-16 2022-05-10 北京大学 能够与膜结合的聚合物及其制备方法和用途
WO2024226815A2 (en) * 2023-04-28 2024-10-31 University Of Washington B-cell epitopes of treponema pallidum antigens for use in a syphilis vaccine

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