JP2019509055A5 - - Google Patents
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- JP2019509055A5 JP2019509055A5 JP2018555841A JP2018555841A JP2019509055A5 JP 2019509055 A5 JP2019509055 A5 JP 2019509055A5 JP 2018555841 A JP2018555841 A JP 2018555841A JP 2018555841 A JP2018555841 A JP 2018555841A JP 2019509055 A5 JP2019509055 A5 JP 2019509055A5
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662278359P | 2016-01-13 | 2016-01-13 | |
| US62/278,359 | 2016-01-13 | ||
| US201662361842P | 2016-07-13 | 2016-07-13 | |
| US62/361,842 | 2016-07-13 | ||
| PCT/US2017/013512 WO2017124002A1 (en) | 2016-01-13 | 2017-01-13 | Multispecific immunomodulatory antigen-binding constructs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019509055A JP2019509055A (ja) | 2019-04-04 |
| JP2019509055A5 true JP2019509055A5 (enExample) | 2020-02-27 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018555841A Withdrawn JP2019509055A (ja) | 2016-01-13 | 2017-01-13 | 多特異性免疫調節抗原結合構築物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20190031785A1 (enExample) |
| EP (1) | EP3402519A4 (enExample) |
| JP (1) | JP2019509055A (enExample) |
| CN (1) | CN109562162A (enExample) |
| AU (1) | AU2017207480A1 (enExample) |
| BR (1) | BR112018014368A2 (enExample) |
| CA (1) | CA3011535A1 (enExample) |
| MA (1) | MA43874A (enExample) |
| WO (1) | WO2017124002A1 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018503399A (ja) * | 2015-01-14 | 2018-02-08 | コンパス セラピューティクス リミテッド ライアビリティ カンパニー | 多特異性免疫調節抗原結合構築物 |
| CN110944651A (zh) * | 2017-02-08 | 2020-03-31 | 蜻蜓疗法股份有限公司 | 用于自然杀伤细胞激活的多特异性结合蛋白及其治疗癌症的治疗性用途 |
| ES2955074T3 (es) | 2017-02-20 | 2023-11-28 | Dragonfly Therapeutics Inc | Proteínas que se unen a HER2, NKG2D Y CD16 |
| EP3652209A2 (en) | 2017-07-11 | 2020-05-20 | Compass Therapeutics LLC | Agonist antibodies that bind human cd137 and uses thereof |
| MX2020002036A (es) * | 2017-08-23 | 2020-03-24 | Dragonfly Therapeutics Inc | Proteinas de union a nkg2d, cd16 y un antigeno asociado al tumor. |
| WO2019089753A2 (en) | 2017-10-31 | 2019-05-09 | Compass Therapeutics Llc | Cd137 antibodies and pd-1 antagonists and uses thereof |
| US11851497B2 (en) | 2017-11-20 | 2023-12-26 | Compass Therapeutics Llc | CD137 antibodies and tumor antigen-targeting antibodies and uses thereof |
| EP3740505A1 (en) * | 2018-01-16 | 2020-11-25 | Lakepharma Inc. | Bispecific antibody that binds cd3 and another target |
| CA3090236A1 (en) | 2018-02-08 | 2019-08-15 | Dragonfly Therapeutics, Inc. | Combination therapy of cancer involving multi-specific binding proteins that activate natural killer cells |
| SG11202007482WA (en) | 2018-02-08 | 2020-09-29 | Dragonfly Therapeutics Inc | Antibody variable domains targeting the nkg2d receptor |
| KR102832460B1 (ko) | 2018-02-20 | 2025-07-11 | 드래곤플라이 쎄라퓨틱스, 인크. | Cd33, nkg2d, 및 cd16에 결합하는 다중-특이적 결합 단백질, 및 이의 사용 방법 |
| MX2020009116A (es) * | 2018-03-02 | 2020-12-07 | Cdr Life Ag | Proteinas triespecificas de union a antigenos. |
| BR112020023299A2 (pt) * | 2018-05-16 | 2021-02-02 | Dragonfly Therapeutics, Inc. | proteína de ligação nkg2d, cd16 e uma proteína de ativação de fibroblastos |
| AU2019272575A1 (en) * | 2018-05-21 | 2020-12-10 | Compass Therapeutics Llc | Compositions and methods for enhancing the killing of target cells by NK cells |
| TWI848951B (zh) | 2018-06-01 | 2024-07-21 | 瑞士商諾華公司 | 針對ｂｃｍａ之結合分子及其用途 |
| MA53293A (fr) | 2018-08-08 | 2021-11-17 | Dragonfly Therapeutics Inc | Protéines de liaison multi-spécifiques se liant à bcma, nkg2d et cd16, et méthodes d'utilisation |
| EA202091888A1 (ru) | 2018-08-08 | 2020-10-23 | Драгонфлай Терапьютикс, Инк. | Вариабельные домены антител, нацеленные на рецептор nkg2d |
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| MX2021005594A (es) | 2018-11-13 | 2021-10-22 | Compass Therapeutics Llc | Constructos multiespecificos de union contra moleculas de puntos de control y usos de los mismos. |
| JP2022531444A (ja) * | 2019-05-06 | 2022-07-06 | ブラウン ユニバーシティ | 腫瘍細胞に対するｔ細胞を介した細胞傷害効果が増大したｃｈｉ３ｌ１およびｐｄ１に対する二重特異性抗体 |
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| BR112021023048A2 (pt) | 2019-05-21 | 2022-04-19 | Novartis Ag | Moléculas de ligação a cd19 e usos das mesmas |
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| TWI888487B (zh) * | 2020-02-14 | 2025-07-01 | 日商協和麒麟股份有限公司 | 與ｃｄ３結合之雙特異性抗體 |
| CN116249549A (zh) | 2020-03-27 | 2023-06-09 | 诺华股份有限公司 | 用于治疗增殖性疾病和自身免疫病症的双特异性组合疗法 |
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| CN116390933A (zh) | 2020-11-06 | 2023-07-04 | 诺华股份有限公司 | 治疗b细胞恶性肿瘤的抗cd19剂和b细胞靶向剂组合疗法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7527787B2 (en) * | 2005-10-19 | 2009-05-05 | Ibc Pharmaceuticals, Inc. | Multivalent immunoglobulin-based bioactive assemblies |
| DK1272647T3 (en) * | 2000-04-11 | 2014-12-15 | Genentech Inc | Multivalent antibodies and uses thereof |
| EP2626371A1 (en) * | 2007-07-31 | 2013-08-14 | MedImmune, LLC | Multispecific epitope binding proteins and uses thereof |
| JP2014514314A (ja) * | 2011-04-20 | 2014-06-19 | ゲンマブ エー／エス | Ｈｅｒ２およびｃｄ３に対する二重特異性抗体 |
| AU2012316859A1 (en) * | 2011-09-29 | 2014-04-17 | Apo-T B.V. | Multi-specific binding molecules targeting aberrant cells |
| WO2013101909A1 (en) * | 2011-12-27 | 2013-07-04 | Development Center For Biotechnology | Light chain-bridged bispecific antibody |
| JP2018503399A (ja) * | 2015-01-14 | 2018-02-08 | コンパス セラピューティクス リミテッド ライアビリティ カンパニー | 多特異性免疫調節抗原結合構築物 |
-
2017
- 2017-01-13 CA CA3011535A patent/CA3011535A1/en not_active Abandoned
- 2017-01-13 AU AU2017207480A patent/AU2017207480A1/en not_active Abandoned
- 2017-01-13 MA MA043874A patent/MA43874A/fr unknown
- 2017-01-13 EP EP17739081.2A patent/EP3402519A4/en not_active Withdrawn
- 2017-01-13 CN CN201780006606.8A patent/CN109562162A/zh active Pending
- 2017-01-13 WO PCT/US2017/013512 patent/WO2017124002A1/en not_active Ceased
- 2017-01-13 JP JP2018555841A patent/JP2019509055A/ja not_active Withdrawn
- 2017-01-13 BR BR112018014368A patent/BR112018014368A2/pt not_active IP Right Cessation
- 2017-01-13 US US16/069,981 patent/US20190031785A1/en not_active Abandoned
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