JP2019507341A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019507341A5 JP2019507341A5 JP2018540821A JP2018540821A JP2019507341A5 JP 2019507341 A5 JP2019507341 A5 JP 2019507341A5 JP 2018540821 A JP2018540821 A JP 2018540821A JP 2018540821 A JP2018540821 A JP 2018540821A JP 2019507341 A5 JP2019507341 A5 JP 2019507341A5
- Authority
- JP
- Japan
- Prior art keywords
- sample
- hours
- test protein
- digestion period
- protease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662291216P | 2016-02-04 | 2016-02-04 | |
| US62/291,216 | 2016-02-04 | ||
| PCT/US2017/016549 WO2017136753A1 (en) | 2016-02-04 | 2017-02-03 | Methods for identifying and analyzing amino acid sequences of proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019507341A JP2019507341A (ja) | 2019-03-14 |
| JP2019507341A5 true JP2019507341A5 (https=) | 2020-03-12 |
| JP7224914B2 JP7224914B2 (ja) | 2023-02-20 |
Family
ID=58046784
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018540821A Active JP7224914B2 (ja) | 2016-02-04 | 2017-02-03 | タンパク質のアミノ酸配列の同定及び分析方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20210255194A1 (https=) |
| EP (1) | EP3411719A1 (https=) |
| JP (1) | JP7224914B2 (https=) |
| CN (1) | CN109073655A (https=) |
| AU (1) | AU2017214586A1 (https=) |
| CA (1) | CA3013340A1 (https=) |
| MX (1) | MX2018009339A (https=) |
| WO (1) | WO2017136753A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015057910A1 (en) | 2013-10-16 | 2015-04-23 | Oncobiologics, Inc. | Buffer formulations for enhanced antibody stability |
| EP3247718B1 (en) | 2015-01-21 | 2021-09-01 | Outlook Therapeutics, Inc. | Modulation of charge variants in a monoclonal antibody composition |
| CN109563161A (zh) | 2016-02-03 | 2019-04-02 | 安口生物公司 | 用于提高抗体稳定性的缓冲制剂 |
| IL277106B2 (en) * | 2018-03-13 | 2024-03-01 | Amgen Inc | Sequential digestion of polypeptides for mass spectrometric analysis |
| CA3123052A1 (en) * | 2019-01-16 | 2020-07-23 | Regeneron Pharmaceuticals, Inc. | Method and system of identifying and quantifying antibody fragmentation |
| CN111579702A (zh) * | 2019-02-18 | 2020-08-25 | 上海美吉生物医药科技有限公司 | 一种蛋白质氨基酸序列覆盖度的检测方法 |
| FR3096459B1 (fr) * | 2019-05-20 | 2024-03-08 | Ct Hospitalier Universitaire Montpellier | Procédé de préparation d’un échantillon peptidique |
| WO2021061658A1 (en) * | 2019-09-23 | 2021-04-01 | Genzyme Corporation | Product quality attribute measurement |
| EP4453944A1 (en) * | 2021-12-23 | 2024-10-30 | F. Hoffmann-La Roche AG | Method of extracting information about protein sequence modifications |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2243230A1 (en) * | 1998-07-15 | 2000-01-15 | Aled Edwards | A device and method for the determination of protein domain boundaries |
| DE602008000796D1 (de) * | 2008-01-15 | 2010-04-22 | Univ Utrecht Holding Bv | Verfahren zur Bestimmung der Aminosäurensequenz von Peptiden |
| US20120053080A1 (en) * | 2009-03-09 | 2012-03-01 | Juan Cui | Protein markers identification for gastric cancer diagnosis |
| CA2763164A1 (en) * | 2009-06-05 | 2010-12-09 | Momenta Pharmaceuticals, Inc. | Methods of modulating fucosylation of glycoproteins |
| JPWO2012111249A1 (ja) * | 2011-02-14 | 2014-07-03 | 学校法人麻布獣医学園 | 質量分析法における質量変化を検出する方法及び安定同位体標識タンパク質の絶対量の定量方法 |
| US9163276B2 (en) * | 2011-07-22 | 2015-10-20 | Tohoku University | Method for fabricating stable-isotope-labeled target peptide fragment in mass spectrometry |
| AU2012318590B2 (en) * | 2011-10-04 | 2017-05-18 | Expression Pathology, Inc. | SRM/MRM assay for the ephrin type-A receptor 2 protein |
| JP5874587B2 (ja) * | 2012-09-10 | 2016-03-02 | 株式会社島津製作所 | アミノ酸配列解析方法及び装置 |
| EP3114476A4 (en) * | 2013-10-03 | 2017-11-01 | Bioanalytix, Inc. | Mass spectrometry-based method for identifying and maintaining quality control factors during the development and manufacture of a biologic |
| CN105044222B (zh) * | 2014-12-19 | 2017-09-12 | 浙江辉肽生命健康科技有限公司 | 生物活性多肽的分析测试和鉴定方法 |
-
2017
- 2017-02-03 CN CN201780019687.5A patent/CN109073655A/zh active Pending
- 2017-02-03 JP JP2018540821A patent/JP7224914B2/ja active Active
- 2017-02-03 WO PCT/US2017/016549 patent/WO2017136753A1/en not_active Ceased
- 2017-02-03 CA CA3013340A patent/CA3013340A1/en not_active Abandoned
- 2017-02-03 MX MX2018009339A patent/MX2018009339A/es unknown
- 2017-02-03 EP EP17705543.1A patent/EP3411719A1/en not_active Ceased
- 2017-02-03 AU AU2017214586A patent/AU2017214586A1/en not_active Abandoned
- 2017-02-03 US US16/072,989 patent/US20210255194A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019507341A5 (https=) | ||
| Lin et al. | Protein–protein interactions: co-immunoprecipitation | |
| Gunawardana et al. | The human tau interactome: binding to the ribonucleoproteome, and impaired binding of the proline-to-leucine mutant at position 301 (P301L) to chaperones and the proteasome | |
| Dunham et al. | Affinity‐purification coupled to mass spectrometry: Basic principles and strategies | |
| WO2019089851A8 (en) | Methods and kits using nucleic acid encoding and/or label | |
| Carrera et al. | Fast monitoring of species-specific peptide biomarkers using high-intensity-focused-ultrasound-assisted tryptic digestion and selected MS/MS ion monitoring | |
| Singh et al. | Characterization of protein cross-links via mass spectrometry and an open-modification search strategy | |
| WO2019236749A3 (en) | Methods and applications of protein identification | |
| Edfors et al. | Immunoproteomics using polyclonal antibodies and stable isotope–labeled affinity-purified recombinant proteins | |
| Cid-Uribe et al. | The diversity of venom components of the scorpion species Paravaejovis schwenkmeyeri (Scorpiones: Vaejovidae) revealed by transcriptome and proteome analyses | |
| JP2020533612A5 (https=) | ||
| JP2009531679A5 (ja) | 複合タンパク質混合物中の被分析タンパク質および／または被分析ペプチドを検出および／または濃縮するための方法 | |
| Fortis et al. | A new approach for the detection and identification of protein impurities using combinatorial solid phase ligand libraries | |
| Schwenk et al. | Comparative protein profiling of serum and plasma using an antibody suspension bead array approach | |
| SE0302559D0 (sv) | Method | |
| Gomase et al. | Immunoproteomics: A review of techniques, applications, and advancements | |
| WO2015030585A2 (en) | Methods for detecting post-translationally modified lysines in a polypeptide | |
| Li et al. | Highly efficient purification of protein complexes from mammalian cells using a novel streptavidin‐binding peptide and hexahistidine tandem tag system: Application to Bruton's tyrosine kinase | |
| Gonczarowska-Jorge et al. | Variable digestion strategies for phosphoproteomics analysis | |
| WO2003073351A3 (en) | Screening process | |
| Shi et al. | Quantitative analysis of membrane proteins from breast cancer cell lines BT474 and MCF7 using multistep solid phase mass tagging and 2D LC/MS | |
| Zoumaro-Djayoon et al. | Targeted analysis of tyrosine phosphorylation by immuno-affinity enrichment of tyrosine phosphorylated peptides prior to mass spectrometric analysis | |
| Santucci et al. | From hundreds to thousands: Widening the normal human Urinome | |
| WO2003070768A3 (en) | Cd40 splice variants,method of detection thereof, compositions comprising said variant(s) or nucleic acid encoding the same and use thereof | |
| Bostrom et al. | Investigating the applicability of antibodies generated within the human protein atlas as capture agents in immunoenrichment coupled to mass spectrometry |