JP2019505554A5 - - Google Patents
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- JP2019505554A5 JP2019505554A5 JP2018543637A JP2018543637A JP2019505554A5 JP 2019505554 A5 JP2019505554 A5 JP 2019505554A5 JP 2018543637 A JP2018543637 A JP 2018543637A JP 2018543637 A JP2018543637 A JP 2018543637A JP 2019505554 A5 JP2019505554 A5 JP 2019505554A5
- Authority
- JP
- Japan
- Prior art keywords
- vaccine
- antagonist
- infection
- dose
- doses
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022152120A JP7813209B2 (ja) | 2016-02-19 | 2022-09-26 | Il-4rアンタゴニストを投与することによるワクチンの有効性を増強する方法 |
| JP2024087570A JP2024112987A (ja) | 2016-02-19 | 2024-05-30 | Il-4rアンタゴニストを投与することによるワクチンの有効性を増強する方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662297257P | 2016-02-19 | 2016-02-19 | |
| US62/297,257 | 2016-02-19 | ||
| US201662409936P | 2016-10-19 | 2016-10-19 | |
| US62/409,936 | 2016-10-19 | ||
| PCT/US2017/018487 WO2017143270A1 (en) | 2016-02-19 | 2017-02-17 | Methods for enhancing efficacy of a vaccine by administering an il-4r antagonist |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022152120A Division JP7813209B2 (ja) | 2016-02-19 | 2022-09-26 | Il-4rアンタゴニストを投与することによるワクチンの有効性を増強する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019505554A JP2019505554A (ja) | 2019-02-28 |
| JP2019505554A5 true JP2019505554A5 (enExample) | 2020-03-26 |
| JP7597500B2 JP7597500B2 (ja) | 2024-12-10 |
Family
ID=58192407
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018543637A Active JP7597500B2 (ja) | 2016-02-19 | 2017-02-17 | Il-4rアンタゴニストを投与することによるワクチンの有効性を増強する方法 |
| JP2022152120A Active JP7813209B2 (ja) | 2016-02-19 | 2022-09-26 | Il-4rアンタゴニストを投与することによるワクチンの有効性を増強する方法 |
| JP2024087570A Abandoned JP2024112987A (ja) | 2016-02-19 | 2024-05-30 | Il-4rアンタゴニストを投与することによるワクチンの有効性を増強する方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022152120A Active JP7813209B2 (ja) | 2016-02-19 | 2022-09-26 | Il-4rアンタゴニストを投与することによるワクチンの有効性を増強する方法 |
| JP2024087570A Abandoned JP2024112987A (ja) | 2016-02-19 | 2024-05-30 | Il-4rアンタゴニストを投与することによるワクチンの有効性を増強する方法 |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US10314904B2 (enExample) |
| EP (2) | EP3416685B1 (enExample) |
| JP (3) | JP7597500B2 (enExample) |
| KR (1) | KR102868264B1 (enExample) |
| CN (1) | CN109069625A (enExample) |
| AU (2) | AU2017220184B2 (enExample) |
| CA (1) | CA3014202A1 (enExample) |
| ES (1) | ES2983475T3 (enExample) |
| HU (1) | HUE067673T2 (enExample) |
| IL (1) | IL261025A (enExample) |
| MA (1) | MA44238B1 (enExample) |
| MX (2) | MX2018009990A (enExample) |
| PL (1) | PL3416685T3 (enExample) |
| PT (1) | PT3416685T (enExample) |
| RU (1) | RU2753869C2 (enExample) |
| WO (1) | WO2017143270A1 (enExample) |
| ZA (1) | ZA201805295B (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| US9574004B2 (en) | 2012-08-21 | 2017-02-21 | Sanofi Biotechnology | Methods for treating or preventing asthma by administering an IL-4R antagonist |
| PT3889181T (pt) | 2012-09-07 | 2024-05-29 | Regeneron Pharma | Um anticorpo antagonista de il-4r para utilização no tratamento da dermatite atópica por administração |
| TWI633891B (zh) | 2013-06-04 | 2018-09-01 | 再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
| TWI682781B (zh) | 2013-07-11 | 2020-01-21 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑治療嗜酸性食道炎的方法 |
| WO2015130975A1 (en) | 2014-02-28 | 2015-09-03 | Regeneron Pharmaceuticals, Inc. | Methods for treating skin infection by administering an il-4r antagonist |
| AU2015346150B2 (en) | 2014-11-14 | 2021-08-19 | Regeneron Pharmaceuticals, Inc. | Methods for treating chronic sinusitis with nasal polyps by administering an IL-4R antagonist |
| WO2017196943A1 (en) * | 2016-05-10 | 2017-11-16 | Minneapolis Medical Research Foundation | Cytokine signaling immunomodulators and methods |
| HUE067888T2 (hu) * | 2016-09-01 | 2024-11-28 | Regeneron Pharma | Módszerek az allergia megelõzésére vagy kezelésére egy IL-4R antagonista adagolásával |
| WO2018057776A1 (en) | 2016-09-22 | 2018-03-29 | Regeneron Pharmaceuticals, Inc. | Methods for treating severe atopic dermatitis by administering an il-4r inhibitor |
| US11053309B2 (en) | 2017-08-04 | 2021-07-06 | Regeneron Pharmaceuticals, Inc. | Methods for treating active eosinophilic esophagitis |
| CA3079946A1 (en) | 2017-10-30 | 2019-05-09 | Sanofi Biotechnology | Methods for treating or preventing asthma by administering an il-4r antagonist |
| US11292847B2 (en) | 2018-05-13 | 2022-04-05 | Regeneron Pharmaceuticals, Inc. | Methods for treating atopic dermatitis by administering an IL-4R inhibitor |
| WO2020092015A1 (en) | 2018-11-02 | 2020-05-07 | University Of Rochester | Therapeutic mitigation of epithelial infection |
| MX2021010560A (es) * | 2019-03-06 | 2021-11-12 | Regeneron Pharma | Inhibidores de la via il-4/il-13 para una eficacia aumentada en el tratamiento de cancer. |
| CA3132587A1 (en) | 2019-03-21 | 2020-09-24 | Regeneron Pharmaceuticals, Inc. | Combination of il-4/il-13 pathway inhibitors and plasma cell ablation for treating allergy |
| BR112022000740A2 (pt) | 2019-07-16 | 2022-07-05 | Sanofi Biotechnology | Métodos para tratamento ou prevenção de asma por administração de um antagonista de il-4r |
| US11504426B2 (en) | 2019-08-05 | 2022-11-22 | Regeneron Pharmaceuticals, Inc. | Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an IL-4R antagonist |
| WO2021026205A1 (en) | 2019-08-05 | 2021-02-11 | Regeneron Pharmaceuticals, Inc. | Methods for treating atopic dermatitis by administering an il-4r antagonist |
| IL293487A (en) | 2019-12-09 | 2022-08-01 | Sanofi Biotechnology | Methods for the treatment of digitally identified il-4/il-13-related disorders |
| EP3992974A1 (en) | 2020-11-02 | 2022-05-04 | Sanofi Biotechnology | Methods for treating digitally-identified il-4/il-13 related disorders |
| MX2022011730A (es) * | 2020-03-27 | 2022-10-13 | Regeneron Pharma | Metodos para el tratamiento de dermatitis atopica mediante la administracion de un antagonista de il-4r. |
| US20240336688A1 (en) * | 2021-07-22 | 2024-10-10 | Icahn School Of Medicine At Mount Sinai | Dual-blockade of il-4 signaling and immune checkpoint proteins for treating cancer |
| IL310962A (en) * | 2021-08-23 | 2024-04-01 | Regeneron Pharma | Methods for treating atopic dermatitis by administering an IL-4R antagonist |
| CN118717989A (zh) * | 2024-05-27 | 2024-10-01 | 中国人民解放军军事科学院军事医学研究院 | Il-4r拮抗剂在制备预防和/或治疗流感病毒感染的药物中的应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2990420T3 (en) | 2000-05-26 | 2017-04-03 | Immunex Corp | USE OF INTERLEUKIN-4 RECEPTOR ANTIBODIES AND COMPOSITIONS THEREOF |
| US20030139364A1 (en) * | 2001-10-12 | 2003-07-24 | University Of Iowa Research Foundation | Methods and products for enhancing immune responses using imidazoquinoline compounds |
| GB0217920D0 (en) * | 2002-04-23 | 2002-09-11 | Aventis Pharm Prod Inc | Interleukin-4 Gene Expression inhibitors |
| BRPI0416603A (pt) | 2003-11-07 | 2007-01-30 | Immunex Corp | anticorpo que se liga ao receptor interleucina-4 (il-4) humano |
| MY149079A (en) | 2006-10-02 | 2013-07-15 | Regeneron Pharma | High affinity human antibodies to human il-4 receptor |
| US7608693B2 (en) * | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| KR101759457B1 (ko) | 2007-12-21 | 2017-07-31 | 메디뮨 리미티드 | 인터루킨-4 수용체 알파(IL-4Rα)에 대한 결합 구성원-173 |
| US8092804B2 (en) | 2007-12-21 | 2012-01-10 | Medimmune Limited | Binding members for interleukin-4 receptor alpha (IL-4Rα)-173 |
| US20120088814A1 (en) * | 2009-03-31 | 2012-04-12 | Isis Pharmaceuticals, Inc. | Methods of modulating an immune response to a viral infection |
| NZ609557A (en) | 2010-10-06 | 2014-12-24 | Regeneron Pharma | Stabilized formulations containing anti-interleukin-4 receptor (il-4r) antibodies |
| EP3530283A1 (en) * | 2012-06-05 | 2019-08-28 | The Australian National University | Vaccination with interleukin-4 antagonists |
| PT3889181T (pt) * | 2012-09-07 | 2024-05-29 | Regeneron Pharma | Um anticorpo antagonista de il-4r para utilização no tratamento da dermatite atópica por administração |
| TWI633891B (zh) | 2013-06-04 | 2018-09-01 | 再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
| CN111437387B (zh) | 2013-06-21 | 2024-10-01 | 赛诺菲生物技术公司 | 通过施用il-4r拮抗剂治疗鼻息肉症的方法 |
| KR20190062142A (ko) * | 2017-11-28 | 2019-06-05 | (주)비티엔 | 면역 증강 활성을 가지는 아미노산 미네랄 복합체 및 이를 포함하는 식품, 약학 또는 사료용 조성물 |
| US20210361700A1 (en) * | 2020-05-22 | 2021-11-25 | Trustees Of Tufts College | Nutritional supplement to combat covid-19 and aid vaccination |
-
2017
- 2017-02-17 AU AU2017220184A patent/AU2017220184B2/en active Active
- 2017-02-17 RU RU2018133011A patent/RU2753869C2/ru active
- 2017-02-17 CA CA3014202A patent/CA3014202A1/en active Pending
- 2017-02-17 KR KR1020187026017A patent/KR102868264B1/ko active Active
- 2017-02-17 CN CN201780014809.1A patent/CN109069625A/zh active Pending
- 2017-02-17 EP EP17708398.7A patent/EP3416685B1/en not_active Revoked
- 2017-02-17 MX MX2018009990A patent/MX2018009990A/es unknown
- 2017-02-17 JP JP2018543637A patent/JP7597500B2/ja active Active
- 2017-02-17 MA MA44238A patent/MA44238B1/fr unknown
- 2017-02-17 PL PL17708398.7T patent/PL3416685T3/pl unknown
- 2017-02-17 EP EP24174931.6A patent/EP4420733A3/en not_active Withdrawn
- 2017-02-17 US US15/436,032 patent/US10314904B2/en active Active
- 2017-02-17 WO PCT/US2017/018487 patent/WO2017143270A1/en not_active Ceased
- 2017-02-17 HU HUE17708398A patent/HUE067673T2/hu unknown
- 2017-02-17 ES ES17708398T patent/ES2983475T3/es active Active
- 2017-02-17 PT PT177083987T patent/PT3416685T/pt unknown
-
2018
- 2018-08-07 IL IL261025A patent/IL261025A/en unknown
- 2018-08-10 ZA ZA2018/05295A patent/ZA201805295B/en unknown
- 2018-08-17 MX MX2024010676A patent/MX2024010676A/es unknown
-
2019
- 2019-04-29 US US16/398,143 patent/US20190321457A1/en not_active Abandoned
-
2022
- 2022-09-26 JP JP2022152120A patent/JP7813209B2/ja active Active
-
2023
- 2023-07-05 US US18/218,459 patent/US20240082380A1/en not_active Abandoned
-
2024
- 2024-05-30 JP JP2024087570A patent/JP2024112987A/ja not_active Abandoned
- 2024-07-18 AU AU2024204962A patent/AU2024204962A1/en active Pending
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