JP2019503176A5 - - Google Patents

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Publication number
JP2019503176A5
JP2019503176A5 JP2018536437A JP2018536437A JP2019503176A5 JP 2019503176 A5 JP2019503176 A5 JP 2019503176A5 JP 2018536437 A JP2018536437 A JP 2018536437A JP 2018536437 A JP2018536437 A JP 2018536437A JP 2019503176 A5 JP2019503176 A5 JP 2019503176A5
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JP
Japan
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allele
il1b
copy
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il1a
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JP2018536437A
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English (en)
Japanese (ja)
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JP2019503176A (ja
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Priority claimed from PCT/US2017/013101 external-priority patent/WO2017123696A1/en
Publication of JP2019503176A publication Critical patent/JP2019503176A/ja
Publication of JP2019503176A5 publication Critical patent/JP2019503176A5/ja
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JP2018536437A 2016-01-12 2017-01-12 処置に対する応答を予測するための方法 Pending JP2019503176A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662277760P 2016-01-12 2016-01-12
US62/277,760 2016-01-12
PCT/US2017/013101 WO2017123696A1 (en) 2016-01-12 2017-01-12 Methods for predicting response to treatment

Publications (2)

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JP2019503176A JP2019503176A (ja) 2019-02-07
JP2019503176A5 true JP2019503176A5 (enExample) 2020-02-20

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JP2018536437A Pending JP2019503176A (ja) 2016-01-12 2017-01-12 処置に対する応答を予測するための方法

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US (2) US10894985B2 (enExample)
EP (1) EP3402900A1 (enExample)
JP (1) JP2019503176A (enExample)
AU (1) AU2017207341A1 (enExample)
CA (1) CA3011363A1 (enExample)
WO (1) WO2017123696A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019503176A (ja) 2016-01-12 2019-02-07 インターロイキン ジェネティクス， インコーポレイテッド 処置に対する応答を予測するための方法
US10337070B2 (en) 2017-01-12 2019-07-02 Cardioforecast Ltd. Methods and kits for treating cardiovascular disease
DE102018104133B4 (de) * 2018-02-23 2025-02-20 Klinikum der Universität München, Anstalt des öffentlichen Rechts Biomarker zur Feststellung einer möglichen Unverträglichkeit gegenüber Metallimplantaten
WO2020087107A1 (en) 2018-10-31 2020-05-07 The University Of Sydney Compositions and methods for treating viral infections
JP7108574B2 (ja) * 2019-04-23 2022-07-28 ジェネシスヘルスケア株式会社 アレルギー性結膜炎のリスクを判定する方法
CA3142662A1 (en) * 2019-06-06 2020-12-10 Sitokine Limited Compositions and methods for treating lung, colorectal and breast cancer
WO2021028469A1 (en) * 2019-08-12 2021-02-18 Sitokine Limited Compositions and methods for treating cytokine release syndrome and neurotoxicity
WO2021205013A1 (en) * 2020-04-09 2021-10-14 Sitokine Limited Compositions and methods for treating covid-19

Family Cites Families (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
NO870613L (no) 1986-03-05 1987-09-07 Molecular Diagnostics Inc Deteksjon av mikroorganismer i en prŸve inneholdende nukleinsyre.
US4988617A (en) 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
ATE173508T1 (de) 1988-05-20 1998-12-15 Hoffmann La Roche Befestigung von sequenzspezifischen proben
US4988167A (en) 1988-08-10 1991-01-29 Fergason James L Light blocking and vision restoration apparatus with glint control
US5118801A (en) 1988-09-30 1992-06-02 The Public Health Research Institute Nucleic acid process containing improved molecular switch
CA2020958C (en) 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
US5494810A (en) 1990-05-03 1996-02-27 Cornell Research Foundation, Inc. Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5539082A (en) 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
US5714331A (en) 1991-05-24 1998-02-03 Buchardt, Deceased; Ole Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
US5270184A (en) 1991-11-19 1993-12-14 Becton, Dickinson And Company Nucleic acid target generation
JP2001507921A (ja) 1992-04-27 2001-06-19 トラスティーズ オブ ダートマス カレッジ 生物学的液体中の遺伝子配列の検出
CA2153387A1 (en) 1993-01-07 1994-07-21 Hubert Koester Dna sequencing by mass spectrometry
US5422252A (en) 1993-06-04 1995-06-06 Becton, Dickinson And Company Simultaneous amplification of multiple targets
US6027923A (en) 1993-07-23 2000-02-22 Bio-Rad Laboratories, Inc. Linked linear amplification of nucleic acids
US5527675A (en) 1993-08-20 1996-06-18 Millipore Corporation Method for degradation and sequencing of polymers which sequentially eliminate terminal residues
US5498531A (en) 1993-09-10 1996-03-12 President And Fellows Of Harvard College Intron-mediated recombinant techniques and reagents
DE4331012A1 (de) 1993-09-13 1995-03-16 Bayer Ag Nukleinsäuren-bindende Oligomere mit N-Verzweigung für Therapie und Diagnostik
US5538848A (en) 1994-11-16 1996-07-23 Applied Biosystems Division, Perkin-Elmer Corp. Method for detecting nucleic acid amplification using self-quenching fluorescence probe
US5657255C1 (en) 1995-04-14 2002-06-11 Interleukin Genetics Inc Hierarchic biological modelling system and method
US5686246A (en) 1995-08-03 1997-11-11 Kornman; Kenneth S. Detecting genetic predisposition to periodontal disease
EP2332957B1 (en) 1996-02-09 2015-04-08 Cornell Research Foundation, Inc. Detection of nucleic and acid sequence differences using the ligase detection reaction with addressable arrays
US5698399A (en) 1996-04-05 1997-12-16 Duff; Gordon W. Detecting genetic predisposition for osteoporosis
US6108635A (en) 1996-05-22 2000-08-22 Interleukin Genetics, Inc. Integrated disease information system
CA2255774C (en) 1996-05-29 2008-03-18 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
US5866336A (en) 1996-07-16 1999-02-02 Oncor, Inc. Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6117635A (en) 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
GB9618960D0 (en) 1996-09-11 1996-10-23 Medical Science Sys Inc Proteases
GB9621129D0 (en) 1996-10-10 1996-11-27 Duff Gordon W Detecting genetic predisposition to sight-threatening diabetic retinopathy
US6210877B1 (en) 1997-03-10 2001-04-03 Interleukin Genetics, Inc. Prediction of coronary artery disease
US6524795B1 (en) 1997-03-10 2003-02-25 Interleukin Genetics, Inc. Diagnostics for cardiovascular disorders
US6720141B1 (en) 1999-11-01 2004-04-13 Interleukin Genetics, Inc. Diagnostics and therapeutics for restenosis
US7820383B2 (en) 1997-03-10 2010-10-26 Interleukin Genetics, Inc. Method for diagnosing myocardial infarction
GB9711040D0 (en) 1997-05-29 1997-07-23 Duff Gordon W Prediction of inflammatory disease
US20050282198A1 (en) 1997-05-29 2005-12-22 Interleukin Genetics, Inc. Diagnostics and therapeutics for diseases associated with an IL-1 inflammatory haplotype
GB9723553D0 (en) 1997-11-07 1998-01-07 Duff Gordon W Prediction of the risk of chronic obstructive airway disease
US6437216B1 (en) 1997-11-13 2002-08-20 Interleukin Genetics Inc. Transgenic models of inflammatory disease
US6746839B1 (en) 1998-01-12 2004-06-08 Interleukin Genetics, Inc. Diagnostics and therapeutics for an obstructive airway disease
US20050032077A1 (en) 1998-03-10 2005-02-10 Duff Gordon W. Detecting genetic predisposition to sight-threatening diabetic retinopathy
US6733967B1 (en) 1998-04-21 2004-05-11 Interleukin Genetics, Inc. Fetal testing for prediction of low birth weight
US6251598B1 (en) 1998-10-30 2001-06-26 Interleukin Genetics, Inc. Methods for diagnosing sepsis
JP2003500005A (ja) 1999-02-10 2003-01-07 インターリューキン ジェネティックス インコーポレイテッド ＩＬ−１β遺伝子の突然変異に基づく治療および診断
US6506594B1 (en) 1999-03-19 2003-01-14 Cornell Res Foundation Inc Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
IL147182A0 (en) 1999-06-30 2002-08-14 Interleukin Genetics Inc Diagnostics and therapeutics for diseases associated with an il-1 inflammatory haplorype
MXPA02002251A (es) 1999-08-30 2003-08-20 Interleukin Genetics Inc Diagnosticos y terapeuticos para osteoporosis.
US20100255475A1 (en) 1999-08-30 2010-10-07 Kornman Kenneth S Diagnostics and therapeutics for osteoporosis
US20090023147A1 (en) 1999-08-30 2009-01-22 Kenneth Kornman Diagnostics and therapeutics for osteoporosis
US20030124524A1 (en) 2000-06-23 2003-07-03 Kenneth Kornman Screening assays for identifying modulators of the inflammatory or immune response
US20060183161A1 (en) 2000-07-17 2006-08-17 Martin Nicklin IL-ILI gene and polypeptide products
EP1373504A2 (en) 2001-01-08 2004-01-02 Interleukin Genetics, Inc. Mammalian tribbles signaling pathways and methods and reagents related thereto
EP1407005A4 (en) 2001-06-11 2006-05-31 Interleukin Genetics Inc INTEGRATIVE TESTING TECHNIQUES FOR CONTROLLING MOLECULAR ASSEMBLY EVENTS
EP1409737A4 (en) 2001-06-15 2005-10-12 Interleukin Genetics Inc METHODS OF DETECTING AND TREATING EARLY APPEARANCE OF CONDITIONS RELATED TO AGING
CN1753903B (zh) 2001-11-19 2010-05-12 白介素遗传公司 影响转录和对炎性和传染性疾病的敏感性的白细胞介素-1基因座的功能多态性
US20080311581A1 (en) 2001-11-19 2008-12-18 David Wyllie Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases
US20070264645A1 (en) 2002-01-25 2007-11-15 Kenneth Kornman IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes
JP2007501627A (ja) 2003-08-08 2007-02-01 インタールーキン ジェネティックス インク 骨粗鬆症のための診断法および治療法
US20080118920A1 (en) 2004-05-03 2008-05-22 Duff Gordon W Diagnostics And Therapeutics For Diseases Associated With An Il-1 Inflammatory Haplotype
US20060252050A1 (en) 2005-05-06 2006-11-09 Ordovas Jose M Genetic marker for weight regulation
US8105775B2 (en) 2005-10-25 2012-01-31 Interleukin Genetics, Inc. IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes
AU2007249801A1 (en) 2006-05-12 2007-11-22 Interleukin Genetics, Inc. Food compositions and methods of treating periodontal disease
ES2431671T3 (es) * 2006-11-15 2013-11-27 Interleukin Genetics, Inc. El complejo génico de IL-1 y resistencia a la insulina: polimorfismos asociados, haplotipos y métodos para usarlos
JP2011502510A (ja) 2007-11-08 2011-01-27 インタールーキン ジェネティクス， インコーポレイテッド 老化に関係がある皮膚疾患の診断
EP2283156B1 (en) 2008-05-02 2015-11-11 Interleukin Genetics, Inc. Detecting genetic predisposition to osteoarthritis associated conditions
WO2009135219A2 (en) 2008-05-02 2009-11-05 Interleukin Genetics, Inc. Detecting genetic predisposition to osteoarthritis associated conditions
US20100136561A1 (en) 2008-05-16 2010-06-03 Interleukin Genetics, Inc. Genetic Markers for Weight Management and Methods of Use Thereof
NZ589863A (en) 2008-05-16 2012-11-30 Interleukin Genetics Inc Genetic markers for weight management and methods of use thereof
CA2731028A1 (en) 2008-07-18 2010-01-21 Interleukin Genetics, Inc. Methods and compositions for pharmacogenetic analysis of anti-inflammatory drugs in the treatment of rheumatoid arthritis and other inflammatory diseases
US20100112570A1 (en) 2008-10-22 2010-05-06 Interleukin Genetics, Inc. Genetic Markers for Weight Management and Methods of Use Thereof
WO2011006070A2 (en) 2009-07-09 2011-01-13 Interleukin Genetics, Inc. Genetic association of polymorphisms in perilipin (plin) gene with resistance to weight loss
US20120208187A1 (en) 2010-12-09 2012-08-16 Kenneth Kornman Method and Kit for Determining Severity and Progression of Periodontal Disease
WO2013049278A1 (en) 2011-09-30 2013-04-04 Novartis Ag USE OF IL-1 ß BINDING ANTIBODIES
WO2013173789A2 (en) 2012-05-17 2013-11-21 Isis Pharmaceuticals, Inc. Antisense oligonucleotide compositions
CA2921162A1 (en) 2013-05-01 2014-11-06 Ionis Pharmaceuticals, Inc. Conjugated antisense compounds and their use
JP2019503176A (ja) 2016-01-12 2019-02-07 インターロイキン ジェネティクス， インコーポレイテッド 処置に対する応答を予測するための方法
US10337070B2 (en) 2017-01-12 2019-07-02 Cardioforecast Ltd. Methods and kits for treating cardiovascular disease

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