|
US7393682B1
(en)
|
1993-03-19 |
2008-07-01 |
The Johns Hopkins University School Of Medicine |
Polynucleotides encoding promyostatin polypeptides
|
|
KR100227406B1
(ko)
|
1993-05-12 |
1999-12-01 |
브루스 엠. 에이센 |
Bmp-11 조성물
|
|
DK0776337T3
(da)
|
1994-07-08 |
2005-12-12 |
Univ Johns Hopkins Med |
Vækstdifferentieringsfaktor-11
|
|
US20030167492A1
(en)
*
|
1994-07-08 |
2003-09-04 |
Johns Hopkins University School Of Medicine |
Transgenic non-human animals expressing a gdf-11 dominant negative polypeptide, and methods of making and using same
|
|
US6008434A
(en)
|
1994-07-08 |
1999-12-28 |
Johns Hopkins University School Of Medicine |
Growth differentiation factor-11 transgenic mice
|
|
JP2001526788A
(ja)
|
1997-05-30 |
2001-12-18 |
クリエイティブ バイオモレキュールズ，インコーポレイテッド |
組織形態形成および活性を評価するための方法
|
|
US6656475B1
(en)
|
1997-08-01 |
2003-12-02 |
The Johns Hopkins University School Of Medicine |
Growth differentiation factor receptors, agonists and antagonists thereof, and methods of using same
|
|
US6696260B1
(en)
|
1997-08-01 |
2004-02-24 |
The Johns Hopkins University School Of Medicine |
Methods to identify growth differentiation factor (GDF) binding proteins
|
|
US6891082B2
(en)
*
|
1997-08-01 |
2005-05-10 |
The Johns Hopkins University School Of Medicine |
Transgenic non-human animals expressing a truncated activintype II receptor
|
|
US7795202B2
(en)
|
1997-08-04 |
2010-09-14 |
Neurorepair, Inc. |
Methods for treating a neurological disorder by peripheral administration of a transforming growth factor alpha (TGF-a)
|
|
US6953662B2
(en)
|
1997-08-29 |
2005-10-11 |
Human Genome Sciences, Inc. |
Follistatin-3
|
|
WO1999024057A2
(en)
|
1997-11-07 |
1999-05-20 |
Genetics Inst |
Neuronal uses of bmp-11
|
|
US20030170213A1
(en)
|
1998-01-23 |
2003-09-11 |
Marc F. Charette |
Methods and compositions for enhancing cognitive function using morphogenic proteins
|
|
DE69940022D1
(de)
|
1998-07-15 |
2009-01-15 |
Metamorphix Inc |
Promotoren für wachstums-differenzierungsfaktoren und deren verwendung
|
|
US7572440B2
(en)
|
1999-07-30 |
2009-08-11 |
Stryker Corporation |
Method for repairing a defect in an intervertebral disc
|
|
US20030224501A1
(en)
|
2000-03-17 |
2003-12-04 |
Young Paul E. |
Bone morphogenic protein polynucleotides, polypeptides, and antibodies
|
|
US20030104977A1
(en)
|
2000-03-31 |
2003-06-05 |
Ugo Ripamonti |
Methods for inducing angiogenesis using morphogenic proteins and stimulatory factors
|
|
EP1790726B1
(en)
|
2001-02-08 |
2013-07-03 |
Wyeth LLC |
Modified and stabilized GDF propeptides and uses thereof
|
|
TWI329129B
(en)
|
2001-02-08 |
2010-08-21 |
Wyeth Corp |
Modified and stabilized gdf propeptides and uses thereof
|
|
US20060078532A1
(en)
|
2004-10-12 |
2006-04-13 |
Omoigui Osemwota S |
Method of prevention and treatment of Atherosclerosis, Peripheral vascular disease, Coronary artery disease, aging and age-related disorders including osteoporosis, arthritis, type 2 diabetes, dementia and Alzheimer's disease
|
|
US20070155661A1
(en)
*
|
2003-02-14 |
2007-07-05 |
The Board Of Trustees Of The Leland Standord Junior University |
Methods and compositions for modulating the development of stem cells
|
|
NZ529860A
(en)
|
2003-11-28 |
2006-10-27 |
Ovita Ltd |
Muscle growth regulator mighty and use in promoting muscle mass and treating muscle wasting diseases
|
|
US7388027B2
(en)
|
2004-03-04 |
2008-06-17 |
Bristol-Myers Squibb Company |
Bicyclic compounds as modulators of androgen receptor function and method
|
|
ATE557042T1
(de)
|
2004-03-23 |
2012-05-15 |
Lilly Co Eli |
Anti-myostatin-antikörper
|
|
AU2005266875B2
(en)
|
2004-07-23 |
2012-07-26 |
Acceleron Pharma Inc. |
ActRII receptor polypeptides, methods and compositions
|
|
US20060216279A1
(en)
|
2005-03-22 |
2006-09-28 |
Glass David J |
Myostatin inhibiting fusion polypeptides and therapeutic methods thereof
|
|
AU2006239860B2
(en)
|
2005-04-25 |
2012-01-19 |
Amgen Fremont Inc. |
Antibodies to myostatin
|
|
US20090215671A1
(en)
|
2005-05-27 |
2009-08-27 |
The Regents Of The University Of California |
Compositions And Methods For Treatment of Neural Disorders Using Transforming Growth Factor-Beta Superfamily Proteins And Their Antagonists
|
|
MX2008002367A
(es)
|
2005-08-19 |
2008-03-18 |
Wyeth Corp |
Anticuerpos antagonistas contra el factor 8 de crecimiento y diferenciacion y usos en el tratamiento de esclerosis lateral amiotrofica y otros trastornos relacionados con el factor 8 de crecimiento y diferenciacion.
|
|
US8067562B2
(en)
|
2005-11-01 |
2011-11-29 |
Amgen Inc. |
Isolated nucleic acid molecule comprising the amino acid sequence of SEQ ID NO:1
|
|
WO2007109686A2
(en)
|
2006-03-20 |
2007-09-27 |
University Of Pittsburgh |
Immunomodulation of inflammatory conditions utilizing follistatin-like protein-1 and agents that bind thereto
|
|
US20080044387A1
(en)
|
2006-03-24 |
2008-02-21 |
The Regents Of The University Of California |
Artificial niches for enhancement of regenerative capacity of stem cells in aged and pathological environments
|
|
US20090298761A1
(en)
|
2006-05-17 |
2009-12-03 |
Donald Engelman |
Methods of treating cartilage defects using a soluble morphogenic protein complex
|
|
WO2008021196A2
(en)
|
2006-08-09 |
2008-02-21 |
The Mclean Hospital Corporation |
Methods and compositions for the treatment of medical disorders
|
|
TWI573802B
(zh)
|
2007-03-06 |
2017-03-11 |
安美基公司 |
變異之活動素受體多肽及其用途
|
|
US8404656B2
(en)
*
|
2007-08-09 |
2013-03-26 |
Children's Hospital Medical Center |
Methods of treatment and prevention of diet-induced obesity and sequelae thereof
|
|
JP5586576B2
(ja)
|
2008-03-20 |
2014-09-10 |
トランスモレキュラー， インコーポレイテッド |
血管新生の阻害
|
|
US8216997B2
(en)
|
2008-08-14 |
2012-07-10 |
Acceleron Pharma, Inc. |
Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
|
|
US8969081B2
(en)
|
2008-12-10 |
2015-03-03 |
The Trustees Of Columbia University In The City Of New York |
Caudal motor neuron derived from embryonic stem cells under conditions essentially free of any retinoid
|
|
WO2010099219A2
(en)
|
2009-02-24 |
2010-09-02 |
The Salk Institute For Biological Studies |
Designer ligands of tgf-beta superfamily
|
|
US20130108645A1
(en)
|
2010-04-13 |
2013-05-02 |
The Johns Hopkins University |
Methods for enhancing axonal regeneration
|
|
US20140127329A1
(en)
|
2011-03-31 |
2014-05-08 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Use of nitrites for the treatment of cerebral amyloid angiopathy, age associated dementia, and cognitive decline
|
|
US8765385B2
(en)
*
|
2011-10-27 |
2014-07-01 |
Ravindra Kumar |
Method of detection of neutralizing anti-actriib antibodies
|
|
ES2779698T3
(es)
|
2012-03-19 |
2020-08-18 |
Brigham & Womens Hospital Inc |
Factor 11 de diferenciación del crecimiento (GDF) para el tratamiento de afecciones cardiovasculares relacionadas con la edad
|
|
WO2014168973A2
(en)
|
2013-04-08 |
2014-10-16 |
President And Fellows Of Harvard College |
Methods and compositions for rejuvenating skeletal muscle stem cells
|
|
US20160220640A1
(en)
|
2013-06-11 |
2016-08-04 |
The Brigham And Women's Hospital, Inc. |
Methods and compositions for increasing neurogenesis and angiogenesis
|
|
CN120796168A
(zh)
|
2013-06-11 |
2025-10-17 |
哈佛学院校长同事会 |
SC-β细胞以及用于产生其的组合物和方法
|
|
US9884090B2
(en)
|
2013-09-03 |
2018-02-06 |
Mayo Foundation For Medical Education And Research |
Using nucleic acids encoding NAP-2 and TGF-alpha polypeptides to improve cardiac function
|
|
WO2015070076A2
(en)
|
2013-11-08 |
2015-05-14 |
President And Fellows Of Harvard College |
Methods and compositions for rejuvenating neuromuscular junctions
|
|
WO2015073396A1
(en)
*
|
2013-11-12 |
2015-05-21 |
The Brigham And Women's Hospital, Inc. |
Growth differentiation factor (gdf) for treatment of diastolic heart failure
|
|
EP3139957A4
(en)
|
2014-05-06 |
2018-04-25 |
Scholar Rock, Inc. |
Compositions and methods for growth factor modulation
|
|
US20170298128A1
(en)
|
2014-09-23 |
2017-10-19 |
President And Fellows Of Harvard College |
Methods and compositions for treating age-related disorders
|
|
EP3949979A1
(en)
|
2016-01-06 |
2022-02-09 |
President and Fellows of Harvard College |
Treatment with gdf11 prevents weight gain, improves glucose tolerance and reduces hepatosteatosis
|
|
JP2019537621A
(ja)
|
2016-10-04 |
2019-12-26 |
フェアバンクス ファーマシューティカルズ，インコーポレイテッド |
抗ｆｓｔｌ３抗体およびその使用
|
|
WO2019144053A1
(en)
|
2018-01-19 |
2019-07-25 |
President And Fellows Of Harward College |
Gdf11 variants and uses thereof
|