JP2019501882A5 - - Google Patents
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- Publication number
- JP2019501882A5 JP2019501882A5 JP2018528340A JP2018528340A JP2019501882A5 JP 2019501882 A5 JP2019501882 A5 JP 2019501882A5 JP 2018528340 A JP2018528340 A JP 2018528340A JP 2018528340 A JP2018528340 A JP 2018528340A JP 2019501882 A5 JP2019501882 A5 JP 2019501882A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- seq
- derived
- beclin
- moiety
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 50
- 108010051109 Cell-Penetrating Peptides Proteins 0.000 claims 15
- 102000020313 Cell-Penetrating Peptides Human genes 0.000 claims 15
- 241000713666 Lentivirus Species 0.000 claims 12
- 238000000034 method Methods 0.000 claims 12
- 239000013603 viral vector Substances 0.000 claims 11
- 241000700605 Viruses Species 0.000 claims 8
- 210000004027 cell Anatomy 0.000 claims 6
- 102000004072 Beclin-1 Human genes 0.000 claims 5
- 108090000524 Beclin-1 Proteins 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- 241000702421 Dependoparvovirus Species 0.000 claims 4
- 241000125945 Protoparvovirus Species 0.000 claims 4
- 239000003623 enhancer Substances 0.000 claims 4
- 241001430294 unidentified retrovirus Species 0.000 claims 4
- 230000026683 transduction Effects 0.000 claims 3
- 238000010361 transduction Methods 0.000 claims 3
- 102000010310 Beclin-2 Human genes 0.000 claims 2
- 108050001838 Beclin-2 Proteins 0.000 claims 2
- 108010016626 Dipeptides Proteins 0.000 claims 2
- 101710121417 Envelope glycoprotein Proteins 0.000 claims 2
- 101001027128 Homo sapiens Fibronectin Proteins 0.000 claims 2
- 241000725303 Human immunodeficiency virus Species 0.000 claims 2
- 241000713772 Human immunodeficiency virus 1 Species 0.000 claims 2
- 102100021696 Syncytin-1 Human genes 0.000 claims 2
- 208000036142 Viral infection Diseases 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 210000000582 semen Anatomy 0.000 claims 2
- 230000009385 viral infection Effects 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 101710150451 Protein Bel-1 Proteins 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 238000000423 cell based assay Methods 0.000 claims 1
- 239000006143 cell culture medium Substances 0.000 claims 1
- 238000001415 gene therapy Methods 0.000 claims 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 claims 1
- 102000040430 polynucleotide Human genes 0.000 claims 1
- 108091033319 polynucleotide Proteins 0.000 claims 1
- 239000002157 polynucleotide Substances 0.000 claims 1
- 230000035945 sensitivity Effects 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 108700026220 vif Genes Proteins 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021162777A JP2022002530A (ja) | 2015-12-03 | 2021-10-01 | ウイルスベクター効率を改善するための組成物及び方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15306924.0 | 2015-12-03 | ||
| EP15306924 | 2015-12-03 | ||
| EP16194180 | 2016-10-17 | ||
| EP16194180.2 | 2016-10-17 | ||
| PCT/EP2016/079304 WO2017093330A1 (en) | 2015-12-03 | 2016-11-30 | Compositions and methods for improving viral vector efficiency |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021162777A Division JP2022002530A (ja) | 2015-12-03 | 2021-10-01 | ウイルスベクター効率を改善するための組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019501882A JP2019501882A (ja) | 2019-01-24 |
| JP2019501882A5 true JP2019501882A5 (cg-RX-API-DMAC7.html) | 2019-10-24 |
| JP7350485B2 JP7350485B2 (ja) | 2023-09-26 |
Family
ID=57485463
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018528340A Active JP7350485B2 (ja) | 2015-12-03 | 2016-11-30 | ウイルスベクター効率を改善するための組成物及び方法 |
| JP2021162777A Pending JP2022002530A (ja) | 2015-12-03 | 2021-10-01 | ウイルスベクター効率を改善するための組成物及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021162777A Pending JP2022002530A (ja) | 2015-12-03 | 2021-10-01 | ウイルスベクター効率を改善するための組成物及び方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11371061B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3383896A1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP7350485B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN108699135B (cg-RX-API-DMAC7.html) |
| CA (1) | CA3004971A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017093330A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2726497B1 (en) * | 2011-06-30 | 2017-06-21 | Genethon | Peptides with viral infection enhancing properties and their use |
| WO2015191508A1 (en) | 2014-06-09 | 2015-12-17 | Voyager Therapeutics, Inc. | Chimeric capsids |
| SG11201703148TA (en) | 2014-11-05 | 2017-05-30 | Voyager Therapeutics Inc | Aadc polynucleotides for the treatment of parkinson's disease |
| CA3193811A1 (en) | 2014-11-14 | 2016-05-19 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (als) |
| DK3218386T3 (da) | 2014-11-14 | 2021-06-07 | Voyager Therapeutics Inc | Modulatorisk polynukleotid |
| US11697825B2 (en) | 2014-12-12 | 2023-07-11 | Voyager Therapeutics, Inc. | Compositions and methods for the production of scAAV |
| WO2017189964A2 (en) | 2016-04-29 | 2017-11-02 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| EP3448874A4 (en) | 2016-04-29 | 2020-04-22 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
| US11951121B2 (en) | 2016-05-18 | 2024-04-09 | Voyager Therapeutics, Inc. | Compositions and methods for treating Huntington's disease |
| AU2017267665C1 (en) | 2016-05-18 | 2023-10-05 | Voyager Therapeutics, Inc. | Modulatory polynucleotides |
| CN110650673B (zh) | 2016-08-30 | 2024-04-09 | 加利福尼亚大学董事会 | 用于生物医学靶向和递送的方法以及用于实践该方法的装置和系统 |
| EP3618839A4 (en) | 2017-05-05 | 2021-06-09 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (als) |
| CN119491003A (zh) | 2017-05-05 | 2025-02-21 | 沃雅戈治疗公司 | 治疗亨廷顿病的组合物和方法 |
| JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
| WO2019018342A1 (en) | 2017-07-17 | 2019-01-24 | Voyager Therapeutics, Inc. | NETWORK EQUIPMENT TRACK GUIDE SYSTEM |
| TWI722310B (zh) | 2017-08-03 | 2021-03-21 | 美商航海家醫療公司 | 用於aav之遞送之組合物及方法 |
| CN111194351A (zh) * | 2017-08-10 | 2020-05-22 | 阿迪根有限公司 | 用于细胞内递送病毒的肽和纳米颗粒 |
| CN107686523B (zh) * | 2017-09-15 | 2021-05-14 | 山西大学 | 一种肿瘤酸度响应自噬诱导多肽及其制备方法和应用 |
| US20200263199A1 (en) | 2017-09-29 | 2020-08-20 | Voyager Therapeutics, Inc. | Rescue of central and peripheral neurological phenotype of friedreich's ataxia by intravenous delivery |
| AU2018352236B2 (en) | 2017-10-16 | 2025-04-10 | The Curators Of The University Of Missouri | Treatment of amyotrophic lateral sclerosis (ALS) |
| WO2019079242A1 (en) | 2017-10-16 | 2019-04-25 | Voyager Therapeutics, Inc. | TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS) |
| US12319929B2 (en) | 2018-05-15 | 2025-06-03 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of Parkinson's disease |
| CA3114621A1 (en) | 2018-09-28 | 2020-04-02 | Voyager Therapeutics, Inc. | Frataxin expression constructs having engineered promoters and methods of use thereof |
| JP7394493B2 (ja) * | 2019-07-31 | 2023-12-13 | レモネックス インコーポレイテッド | 抗癌剤および多孔性シリカ粒子の製造方法 |
| WO2022046800A2 (en) * | 2020-08-24 | 2022-03-03 | University Of Southern California | Beclin 2 and uses thereof for treating cancer and neurodegenerative diseases |
| JP2024506681A (ja) * | 2021-02-15 | 2024-02-14 | バイオマリン ファーマシューティカル インコーポレイテッド | ｒＡＡＶ及びｒＢＶ産生のためのトランスフェクション試薬としてのヒスチジンリッチペプチドの使用 |
| CN113713082B (zh) * | 2021-08-27 | 2023-07-18 | 福建医科大学 | 一种用于阿尔茨海默症的纳米自噬诱导剂及其制备方法与应用 |
| CN114316065B (zh) * | 2021-10-29 | 2023-09-22 | 新乡医学院 | 小分子肽及其应用、细胞培养基、核酸分子 |
| WO2024243639A1 (en) * | 2023-05-31 | 2024-12-05 | The Florey Institute Of Neuroscience And Mental Health | Autophagy-inducing peptides |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7083979B1 (en) | 1994-03-25 | 2006-08-01 | Indiana University Foundation | Methods for enhanced retroviral-mediated gene transfer |
| WO2011106684A2 (en) * | 2010-02-25 | 2011-09-01 | San Diego State University Foundation | Compositions and methods for modulating autophagy |
| EP2726497B1 (en) * | 2011-06-30 | 2017-06-21 | Genethon | Peptides with viral infection enhancing properties and their use |
| CA2864145C (en) * | 2012-02-11 | 2017-02-14 | Board Of Regents Of The University Of Texas System | Autophagy-inducing peptide |
| US20150352228A1 (en) * | 2013-01-11 | 2015-12-10 | Bruce TORBET | Methods and compositions for enhancing transduction efficiency of retroviral vectors |
| US20140271584A1 (en) | 2013-03-15 | 2014-09-18 | The Research Foundation For The State University Of New York | Methods and Compositions for Direct Reprogramming of Somatic Cells to Stem Cells, and Uses of these Cells |
| CA2924969A1 (en) * | 2013-09-18 | 2015-03-26 | Ndsu Research Foundation | Compositions and methods for treating conditions associated with y-herpesviruses |
| WO2016119856A1 (en) * | 2015-01-29 | 2016-08-04 | Universite De Strasbourg | Autophagy-inducing molecules for increasing insulin release |
| EP3141680B1 (en) * | 2015-09-09 | 2018-01-31 | U-Shin Italia S.p.A. | Electronic handle for a vehicle door |
| CN108431033A (zh) * | 2015-09-28 | 2018-08-21 | 泰莱托恩基金会 | 骨生长病症的治疗 |
| WO2017161274A1 (en) * | 2016-03-18 | 2017-09-21 | Trustees Of Tufts College | Cyclic peptide epitopes and small-molecule mimics for inducing autophagy |
| US10774328B2 (en) * | 2016-07-11 | 2020-09-15 | University Of North Texas Health Science Center At Fort Worth | Treatment for glaucoma and other eye diseases |
| WO2018222723A1 (en) * | 2017-05-30 | 2018-12-06 | Vertex Pharmaceuticals Incorporated | C3 fusion protein and methods of making and using thereof |
-
2016
- 2016-11-30 CN CN201680070996.0A patent/CN108699135B/zh not_active Expired - Fee Related
- 2016-11-30 JP JP2018528340A patent/JP7350485B2/ja active Active
- 2016-11-30 US US15/772,902 patent/US11371061B2/en active Active
- 2016-11-30 CA CA3004971A patent/CA3004971A1/en active Pending
- 2016-11-30 WO PCT/EP2016/079304 patent/WO2017093330A1/en not_active Ceased
- 2016-11-30 EP EP16806032.5A patent/EP3383896A1/en not_active Withdrawn
-
2021
- 2021-10-01 JP JP2021162777A patent/JP2022002530A/ja active Pending
-
2022
- 2022-05-23 US US17/750,705 patent/US20230117384A1/en not_active Abandoned
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