JP2019203847A - Artificial body odor composition and evaluation method using the same - Google Patents
Artificial body odor composition and evaluation method using the same Download PDFInfo
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- 208000035985 Body Odor Diseases 0.000 title claims abstract description 77
- 206010040904 Skin odour abnormal Diseases 0.000 title claims abstract description 75
- 239000000203 mixture Substances 0.000 title claims abstract description 60
- 238000011156 evaluation Methods 0.000 title abstract description 15
- PWKJMPFEQOHBAC-UHFFFAOYSA-N 4-Ethyloctanoic acid Chemical compound CCCCC(CC)CCC(O)=O PWKJMPFEQOHBAC-UHFFFAOYSA-N 0.000 claims abstract description 23
- FBUKVWPVBMHYJY-UHFFFAOYSA-N nonanoic acid Chemical compound CCCCCCCCC(O)=O FBUKVWPVBMHYJY-UHFFFAOYSA-N 0.000 claims description 24
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 23
- 229930195729 fatty acid Natural products 0.000 claims description 23
- 239000000194 fatty acid Substances 0.000 claims description 23
- 150000004665 fatty acids Chemical class 0.000 claims description 23
- 125000004432 carbon atom Chemical group C* 0.000 claims description 19
- NTWSIWWJPQHFTO-AATRIKPKSA-N (2E)-3-methylhex-2-enoic acid Chemical compound CCC\C(C)=C\C(O)=O NTWSIWWJPQHFTO-AATRIKPKSA-N 0.000 claims description 16
- RSFQOQOSOMBPEJ-UHFFFAOYSA-N 3-Methyl-2-hexenoic acid Natural products CCC(C)=CC(O)=O RSFQOQOSOMBPEJ-UHFFFAOYSA-N 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 4
- 235000019645 odor Nutrition 0.000 description 65
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 9
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical compound CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 description 8
- 238000002156 mixing Methods 0.000 description 8
- 239000001069 triethyl citrate Substances 0.000 description 8
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 description 8
- 235000013769 triethyl citrate Nutrition 0.000 description 8
- 239000000126 substance Substances 0.000 description 7
- 239000002904 solvent Substances 0.000 description 6
- WWZKQHOCKIZLMA-UHFFFAOYSA-N Caprylic acid Natural products CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 4
- 230000001877 deodorizing effect Effects 0.000 description 4
- 210000004243 sweat Anatomy 0.000 description 4
- XYHKNCXZYYTLRG-UHFFFAOYSA-N 1h-imidazole-2-carbaldehyde Chemical compound O=CC1=NC=CN1 XYHKNCXZYYTLRG-UHFFFAOYSA-N 0.000 description 3
- GWYFCOCPABKNJV-UHFFFAOYSA-M 3-Methylbutanoic acid Natural products CC(C)CC([O-])=O GWYFCOCPABKNJV-UHFFFAOYSA-M 0.000 description 3
- GWYFCOCPABKNJV-UHFFFAOYSA-N beta-methyl-butyric acid Natural products CC(C)CC(O)=O GWYFCOCPABKNJV-UHFFFAOYSA-N 0.000 description 3
- 239000004744 fabric Substances 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 description 2
- 235000009161 Espostoa lanata Nutrition 0.000 description 2
- 240000001624 Espostoa lanata Species 0.000 description 2
- 208000008454 Hyperhidrosis Diseases 0.000 description 2
- GONOPSZTUGRENK-UHFFFAOYSA-N benzyl(trichloro)silane Chemical compound Cl[Si](Cl)(Cl)CC1=CC=CC=C1 GONOPSZTUGRENK-UHFFFAOYSA-N 0.000 description 2
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 2
- KQNPFQTWMSNSAP-UHFFFAOYSA-N isobutyric acid Chemical compound CC(C)C(O)=O KQNPFQTWMSNSAP-UHFFFAOYSA-N 0.000 description 2
- 230000000873 masking effect Effects 0.000 description 2
- FUZZWVXGSFPDMH-UHFFFAOYSA-N n-hexanoic acid Natural products CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 description 2
- BSAIUMLZVGUGKX-UHFFFAOYSA-N non-2-enal Chemical compound CCCCCCC=CC=O BSAIUMLZVGUGKX-UHFFFAOYSA-N 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 208000013460 sweaty Diseases 0.000 description 2
- NQPDZGIKBAWPEJ-UHFFFAOYSA-N valeric acid Chemical compound CCCCC(O)=O NQPDZGIKBAWPEJ-UHFFFAOYSA-N 0.000 description 2
- VKWJULLMBKNPEC-GQCTYLIASA-N (e)-4-methylhex-3-enoic acid Chemical compound CC\C(C)=C\CC(O)=O VKWJULLMBKNPEC-GQCTYLIASA-N 0.000 description 1
- GYSCBCSGKXNZRH-UHFFFAOYSA-N 1-benzothiophene-2-carboxamide Chemical compound C1=CC=C2SC(C(=O)N)=CC2=C1 GYSCBCSGKXNZRH-UHFFFAOYSA-N 0.000 description 1
- POAOYUHQDCAZBD-UHFFFAOYSA-N 2-butoxyethanol Chemical compound CCCCOCCO POAOYUHQDCAZBD-UHFFFAOYSA-N 0.000 description 1
- RGRNSTGIHROKJB-UHFFFAOYSA-N 3-hydroxy-3-methylhexanoic acid Chemical compound CCCC(C)(O)CC(O)=O RGRNSTGIHROKJB-UHFFFAOYSA-N 0.000 description 1
- AWQSAIIDOMEEOD-UHFFFAOYSA-N 5,5-Dimethyl-4-(3-oxobutyl)dihydro-2(3H)-furanone Chemical compound CC(=O)CCC1CC(=O)OC1(C)C AWQSAIIDOMEEOD-UHFFFAOYSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- GHVNFZFCNZKVNT-UHFFFAOYSA-N Decanoic acid Natural products CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- OBETXYAYXDNJHR-UHFFFAOYSA-N alpha-ethylcaproic acid Natural products CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 210000000040 apocrine gland Anatomy 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000001149 cognitive effect Effects 0.000 description 1
- 229940125904 compound 1 Drugs 0.000 description 1
- 229940125782 compound 2 Drugs 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 210000002374 sebum Anatomy 0.000 description 1
- 244000005714 skin microbiome Species 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
- Fats And Perfumes (AREA)
Abstract
Description
本発明は、擬似体臭組成物及びこれを用いる評価方法に関する。 The present invention relates to a simulated body odor composition and an evaluation method using the same.
近年、スポーツする人口の増加、更に、スポーツする際に着用する衣類（例えば、化学繊維）については、汗臭や体臭が残りやすく、衣類に付着する汗臭や体臭のニオイを気にしている生活者が多くなっている。
このような体臭に対するファブリックケア製品を開発する目的で、衣類に付着・残存する体臭を再現し、スクリーニング方法を確立するための体臭モデル臭気の開発が望まれている。
In recent years, an increase in the number of people who sport, and clothes that are worn during sports (for example, chemical fibers) tend to leave sweaty odors and body odors. The number of people is increasing.
For the purpose of developing a fabric care product for such body odor, it is desired to develop a body odor model odor for reproducing the body odor adhering to and remaining on clothing and establishing a screening method.
特許文献１に記載の擬似体臭組成物は、実際の汗臭、特にアポクリン腺の分泌物に由来する特有な臭気を再現しようとするものであり、腋の刺激臭に特化したものである。腋臭は体臭の要素ではあるが、腋臭以外の体幹部分をも含めた体臭を再現するものではない。
特許文献２及び３には擬似腋臭組成物が記載されているが、擬似体臭組成物ではない。
非特許文献１には、腋の下の分泌物中の酸性物質の一例として、４‐エチルオクタン酸が記載されている。
繊維製品評価技術協議会で基準となる汗臭、体臭は、アンモニア、酢酸、イソ吉草酸、ノネナールを用いているが、実衣類でこれらの組合せのみで構成される臭気はなく、総合的な体臭を再現するものではない。
The simulated body odor composition described in Patent Document 1 is intended to reproduce the actual sweat odor, in particular, the unique odor derived from the secretions of the apocrine glands, and is specialized in the irritating odor of wrinkles. Although the bad smell is an element of body odor, it does not reproduce the body odor including the trunk other than the bad smell.
Patent Documents 2 and 3 describe a pseudo odor composition, but are not a pseudo body odor composition.
Non-Patent Document 1 describes 4-ethyloctanoic acid as an example of an acidic substance in the secretions under the armpit.
The sweat odor and body odor, which are the standards in the Textile Product Evaluation Technology Council, are ammonia, acetic acid, isovaleric acid, and nonenal. Is not reproduced.
本発明は、衣類に付着・蓄積残存する体臭を忠実に再現することができる擬似体臭組成物及びこれを用いる評価方法を提供することを目的とする。 An object of this invention is to provide the pseudo body odor composition which can faithfully reproduce the body odor which adheres and accumulate | stores in clothing, and an evaluation method using the same.
本発明者らは、上記課題を解決するために鋭意検討した結果、４‐エチルオクタン酸により、衣類に付着・蓄積残存する体臭を再現し得ることを見出した。本発明は、このような新規な知見に基づいて完成されたものである。
従って、本発明の一実施態様において、４‐エチルオクタン酸を含む擬似体臭組成物が提供される。
本発明の一実施態様によれば、擬似体臭組成物は、４‐エチルオクタン酸以外の炭素数３〜１０の低級脂肪酸１種以上を更に含む。
本発明の一実施態様によれば、４‐エチルオクタン酸以外の炭素数３〜１０の低級脂肪酸は、３‐メチル‐２‐ヘキセン酸及び／又はノナン酸である。
また、本発明の一実施態様において、
（Ａ）４‐エチルオクタン酸、
（Ｂ）３‐メチル‐２‐ヘキセン酸、
（Ｃ）４‐エチルオクタン酸、３‐メチル‐２‐ヘキセン酸及びノナン酸以外の、炭素数３〜１０の低級脂肪酸１種以上、及び
（Ｄ）ノナン酸
を含み、（Ａ）、（Ｂ）、（Ｃ）及び（Ｄ）の質量比が、（Ａ）：（Ｂ）：（Ｃ）：（Ｄ）＝１〜１０：１０〜３０：１〜５：１〜１０である、擬似体臭組成物が提供される。
更に、本発明の一実施態様において、擬似体臭組成物を使用して擬似体臭臭気を評価する方法が提供される。
As a result of intensive studies to solve the above problems, the present inventors have found that 4-ethyloctanoic acid can reproduce body odor that adheres to and accumulates on clothing. The present invention has been completed based on such novel findings.
Accordingly, in one embodiment of the present invention, a simulated odor composition comprising 4-ethyloctanoic acid is provided.
According to one embodiment of the present invention, the simulated odor composition further comprises one or more lower fatty acids having 3 to 10 carbon atoms other than 4-ethyloctanoic acid.
According to one embodiment of the present invention, the lower fatty acid having 3 to 10 carbon atoms other than 4-ethyloctanoic acid is 3-methyl-2-hexenoic acid and / or nonanoic acid.
In one embodiment of the present invention,
(A) 4-ethyloctanoic acid,
(B) 3-methyl-2-hexenoic acid,
(C) one or more lower fatty acids having 3 to 10 carbon atoms other than 4-ethyloctanoic acid, 3-methyl-2-hexenoic acid and nonanoic acid, and (D) containing nonanoic acid, (A), (B ), (C) and (D) mass ratio of (A) :( B) :( C) :( D) = 1-10: 10-30: 1-5: 1-10 A composition is provided.
Furthermore, in one embodiment of the present invention, a method for evaluating a simulated body odor odor using a simulated body odor composition is provided.
本発明の擬似体臭組成物により、衣類に付着・蓄積残存する体臭を再現し得る。 With the simulated body odor composition of the present invention, the body odor adhered to and accumulated on clothing can be reproduced.
本発明は、衣類、特には、普段着用している肌着、Ｔシャツなど肌に直接触れる衣類に付着・蓄積残存する体臭を再現する擬似体臭組成物、及びこれを用いた臭気評価方法に関するものである。
本明細書において、「体臭」とは、肌着等の衣類の胸部や首、背面部に主に感じる比較的脂っぽい臭気のことである。また、本明細書において、「擬似体臭」とは、肌着等の衣類の胸部や首、背面部に主に感じる比較的脂っぽい臭気を擬似的に再現したものである。
なお、衣類に付着・蓄積残存する不快な臭気としては、腋臭や、汗や菌由来の非常に酸っぱい臭気もあるが、これらは本明細書に示す体臭とは異なる。
The present invention relates to a simulated body odor composition that reproduces body odor that adheres to and accumulates on clothing, in particular, underwear that is usually worn, clothing that directly touches the skin, such as T-shirts, and an odor evaluation method using the same. is there.
In this specification, “body odor” refers to a relatively greasy odor that is mainly felt on the chest, neck, and back of clothing such as underwear. In the present specification, the “pseudo body odor” is a pseudo reproduction of a relatively greasy odor mainly felt on the chest, neck, and back of clothing such as underwear.
The unpleasant odor that remains attached to and accumulates on clothing includes a habit odor and a very sour odor derived from sweat and bacteria, but these are different from the body odor shown in this specification.
［４‐エチルオクタン酸：（Ａ）成分］
４‐エチルオクタン酸は、不快なニオイ成分として知られている成分であり、臭気成分としてはアニマリックな臭気をもたらすものである。本発明の擬似体臭組成物において、この成分が含まれることにより、着用後の衣類に付着・蓄積残存する体臭、特には、着用後の衣類に付着・残存する皮脂に由来する体臭の再現性が高まる。これは、４‐エチルオクタン酸が発するアニマリックな臭気が、単にその他低級脂肪酸によりもたらされる臭気にはない、衣類の布のニオイ（古着的な古めかしいニオイ）を再現するためである。
本発明の擬似体臭組成物中、４‐エチルオクタン酸の配合量は特に限定されないが、擬似体臭組成物の総質量に対して、０．０１〜０．２質量％が好ましく、０．０１〜０．１質量％がより好ましい。４‐エチルオクタン酸の配合量が０．０１〜０．２質量％の範囲内であると、その臭気が強すぎず、より衣類に付着・残留する体臭を再現するのに適している。
[4-ethyloctanoic acid: component (A)]
4-Ethyloctanoic acid is a component known as an unpleasant odor component, and as an odor component, it produces an animal odor. By including this component in the simulated body odor composition of the present invention, body odor that adheres to and accumulates on clothing after wearing, in particular, reproducibility of body odor derived from sebum that adheres to and remains on clothing after wearing. Rise. This is due to the reproduction of the odor of clothing cloth (the old-fashioned and old-fashioned odor) that the odor produced by 4-ethyloctanoic acid is not simply the odor caused by other lower fatty acids.
In the simulated body odor composition of the present invention, the amount of 4-ethyloctanoic acid is not particularly limited, but is preferably 0.01 to 0.2% by mass with respect to the total mass of the simulated body odor composition, 0.01 to 0.1 mass% is more preferable. When the blending amount of 4-ethyloctanoic acid is in the range of 0.01 to 0.2% by mass, the odor is not too strong, and it is more suitable for reproducing the body odor adhering to and remaining on clothing.
［３‐メチル‐２‐ヘキセン酸：（Ｂ）成分］
３‐メチル‐２‐ヘキセン酸は、腋臭症の原因物質の研究において、古い雑巾のような脂肪酸臭をもたらす成分として知られている。３‐メチル‐２‐ヘキセン酸とグルタミンが結合した分泌物が、皮膚の細菌により分解されて臭気が発生するといわれている。このニオイは、腋臭の臭気の一部となる。
着用した衣類に付着・蓄積残存する臭気としては、炭素数３〜１０の低級脂肪酸によるものが挙げられる。例えば、酢酸は汗の酸っぱいニオイであったり、イソ吉草酸も汗様の脂肪酸臭に独特のツンとした臭気が加わったもの、同様にヘキサン酸も汗っぽい脂肪酸として捉えられるようなものとして存在するが、３‐メチル‐２‐ヘキセン酸の臭気は、腋臭の臭気に似ている。本発明の擬似体臭組成物において、この成分を加えると、衣類の腋部に付着する成分の臭気の再現性を高めることになり、腋臭の要素も含む擬似体臭組成物の再現性が高まる。
本発明の擬似体臭組成物中、３‐メチル‐２‐ヘキセン酸の配合量は特に限定されないが、擬似体臭組成物の総質量に対して、０．０１〜０．３質量％が好ましく、０．１〜０．２質量％がより好ましい。３‐メチル‐２‐ヘキセン酸の配合量が０．０１〜０．３質量％の範囲内であると、腋臭の特徴が出過ぎず、臭気のバランスよく体臭を再現し、所謂、衣類に付着・蓄積残存する脂っぽいニオイや衣類っぽさの臭気を再現する４‐エチルオクタン酸による臭気を十分に残すことができる。
[3-Methyl-2-hexenoic acid: component (B)]
3-Methyl-2-hexenoic acid is known as a component that causes fatty acid odor like old rags in the study of causative substances of odor. It is said that a secreted product of 3-methyl-2-hexenoic acid and glutamine is decomposed by skin bacteria to generate an odor. This odor becomes part of the odor of odor.
Examples of the odor adhering to and accumulating on the worn clothing include those derived from lower fatty acids having 3 to 10 carbon atoms. For example, acetic acid is a sour odor of sweat, isovaleric acid is a sweat-like fatty acid odor with a unique odor, and hexanoic acid is also perceived as a sweaty fatty acid. However, the odor of 3-methyl-2-hexenoic acid is similar to the odor of odor. In the simulated body odor composition of the present invention, when this component is added, the reproducibility of the odor of the component adhering to the heel of clothing is increased, and the reproducibility of the simulated body odor composition including the element of the odor is increased.
In the simulated body odor composition of the present invention, the amount of 3-methyl-2-hexenoic acid is not particularly limited, but is preferably 0.01 to 0.3% by mass with respect to the total mass of the simulated body odor composition. .1 to 0.2% by mass is more preferable. When the blending amount of 3-methyl-2-hexenoic acid is within the range of 0.01 to 0.3% by mass, the characteristics of the odor are not excessive, and the body odor is reproduced with a well-balanced odor. The odor due to 4-ethyloctanoic acid that reproduces the accumulated fat-like odor and clothing-like odor can be retained.
［炭素数３〜１０の低級脂肪酸：（Ｃ）成分］
炭素数３〜１０の低級脂肪酸は、着用回収した肌着類より検出される臭気成分である。なお、本発明の擬似体臭組成物において、４‐エチルオクタン酸、３‐メチル‐２‐ヘキセン酸及びノナン酸も炭素数３〜１０の低級脂肪酸であることから、これらの具体的成分が含まれる擬似体臭組成物中においては、炭素数３〜１０の低級脂肪酸は、当該具体的成分以外のものを指す。例えば、ある態様では、炭素数３〜１０の低級脂肪酸は、４‐エチルオクタン酸以外の炭素数３〜１０の低級脂肪酸であり得るし、またある態様では、炭素数３〜１０の低級脂肪酸は、４‐エチルオクタン酸、３‐メチル‐２‐ヘキセン酸及びノナン酸以外の炭素数３〜１０の低級脂肪酸であり得る。
本発明の擬似体臭組成物において、炭素数３〜１０の低級脂肪酸を１種以上配合することができる。
本発明の擬似体臭組成物に含まれ得る炭素数３〜１０の低級脂肪酸の具体例としては、３‐メチル‐２‐ヘキセン酸、ノナン酸、酢酸、酪酸、イソ酪酸、イソ吉草酸、ヘキサン酸、ヘプタン酸、オクタン酸、４‐メチル‐３‐ヘキセン酸、３‐ヒドロキシ‐３‐メチルヘキサン酸、デカン酸、ペンタン酸等が挙げられるが、これらに限定されるものではない。
本発明の擬似体臭組成物中、炭素数３〜１０の低級脂肪酸の配合量は特に限定されないが、擬似体臭組成物の総質量に対して、０．１質量％以下が好ましく、０．０５質量％以下がより好ましい。
[Lower fatty acid having 3 to 10 carbon atoms: component (C)]
The lower fatty acid having 3 to 10 carbon atoms is an odor component detected from the underwear collected and worn. In the simulated odor composition of the present invention, 4-ethyloctanoic acid, 3-methyl-2-hexenoic acid and nonanoic acid are also lower fatty acids having 3 to 10 carbon atoms, and therefore these specific components are included. In the simulated body odor composition, the lower fatty acid having 3 to 10 carbon atoms refers to a substance other than the specific component. For example, in one embodiment, the lower fatty acid having 3 to 10 carbon atoms can be a lower fatty acid having 3 to 10 carbon atoms other than 4-ethyloctanoic acid, and in one embodiment, the lower fatty acid having 3 to 10 carbon atoms is It may be a lower fatty acid having 3 to 10 carbon atoms other than 4-ethyloctanoic acid, 3-methyl-2-hexenoic acid and nonanoic acid.
In the simulated body odor composition of the present invention, one or more lower fatty acids having 3 to 10 carbon atoms can be blended.
Specific examples of the lower fatty acid having 3 to 10 carbon atoms that can be included in the simulated odor composition of the present invention include 3-methyl-2-hexenoic acid, nonanoic acid, acetic acid, butyric acid, isobutyric acid, isovaleric acid, and hexanoic acid. , Heptanoic acid, octanoic acid, 4-methyl-3-hexenoic acid, 3-hydroxy-3-methylhexanoic acid, decanoic acid, pentanoic acid and the like, but are not limited thereto.
In the simulated body odor composition of the present invention, the blending amount of the lower fatty acid having 3 to 10 carbon atoms is not particularly limited, but is preferably 0.1% by mass or less, and 0.05 mass with respect to the total mass of the simulated body odor composition. % Or less is more preferable.
［ノナン酸：（Ｄ）成分］
ノナン酸は、炭素数３〜１０の低級脂肪酸の中で、着用回収した肌着類から検出される最も特徴的な成分である。
本発明の擬似体臭組成物中、ノナン酸の配合量は特に限定されないが、擬似体臭組成物の総質量に対して、0.01〜0.1質量％が好ましく、０．０１〜０．０５質量％がより好ましい。
[Nonanoic acid: component (D)]
Nonanoic acid is the most characteristic component detected from underwear collected and recovered among lower fatty acids having 3 to 10 carbon atoms.
In the simulated body odor composition of the present invention, the amount of nonanoic acid is not particularly limited, but is preferably 0.01 to 0.1% by weight, more preferably 0.01 to 0.05% by weight, based on the total weight of the simulated body odor composition. preferable.
本発明の擬似体臭組成物において、上記（Ａ）、（Ｂ）、（Ｃ）及び（Ｄ）成分の配合割合は、特に限定されないが、（Ａ）、（Ｂ）、（Ｃ）及び（Ｄ）の質量比が、（Ａ）：（Ｂ）：（Ｃ）：（Ｄ）＝１〜１０：１０〜３０：１〜５：１〜１０であることが好ましい。このような配合割合の範囲内であると、より忠実に衣類に付着・蓄積残存する体臭を再現し得る。 In the simulated body odor composition of the present invention, the mixing ratio of the components (A), (B), (C) and (D) is not particularly limited, but (A), (B), (C) and (D ) Mass ratio is preferably (A) :( B) :( C) :( D) = 1 to 10:10 to 30: 1 to 5: 1 to 10. Within such a blending ratio range, the body odor that adheres to and accumulates on clothing can be reproduced more faithfully.
［溶剤］
本発明の擬似体臭組成物において、溶剤を配合し得る。溶剤としては、本発明の擬似体臭組成物の擬似体臭に影響を与えないものであれば特に限定されないが、例えば、トリエチルシトレイト（TEC）、ジプロピレングリコール（ＤＰＧ）、エチレングリコールモノブチルエーテル（ＢＥＧ）等が挙げられる。
本発明の擬似体臭組成物中、溶剤の配合量は特に限定されないが、擬似体臭組成物の総質量に対して、９０.０〜９９.９質量％が好ましく、９９．０〜９９．９質量％がより好ましい。
[solvent]
In the simulated body odor composition of the present invention, a solvent may be blended. The solvent is not particularly limited as long as it does not affect the pseudo odor of the pseudo odor composition of the present invention. For example, triethyl citrate (TEC), dipropylene glycol (DPG), ethylene glycol monobutyl ether (BEG) ) And the like.
In the simulated body odor composition of the present invention, the blending amount of the solvent is not particularly limited, but is preferably 99.0 to 99.9% by weight, and 99.0 to 99.9% by weight based on the total weight of the simulated body odor composition. % Is more preferable.
［評価方法］
本発明の擬似体臭組成物の体臭類似性については、混合した成分について、その臭気を３〜１０名の専門パネルを用い、その再現性、類似性を判定することにより行われ得る。
具体的には、調整した擬似体臭組成物をにおい紙につけ、直後ににおい紙のにおいを嗅ぎ評価を行う。調整された本発明の擬似体臭組成物は、実際に存在する衣類に付着・蓄積残存する様々な体臭をより正確に再現することができる。従って、本発明の擬似体臭組成物を使用して衣類に付着・蓄積残存する擬似体臭臭気を評価することができる。更に、本発明の擬似体臭組成物を使用して、衣類に付着・蓄積残存する体臭のマスキング又は消臭効果を的確に且つ簡易に評価できる。つまり、本発明の擬似体臭組成物を使用して、衣類に付着・蓄積残存する体臭に対してその臭いのマスキング作用又は消臭作用を有する物質を効率よくスクリーニングすることができる。
本発明の擬似体臭組成物を使用した衣類に付着・蓄積残存する体臭を消臭する評価、即ち、体臭の強度の評価方法は、例えば、容量既知の密栓できるバイアル瓶を用意し、そこに、綿球を入れて、そこに規定量の擬似体臭組成物を添加し、その臭気を嗅ぎ、次いで被検体（消臭作用する物質）を加えた際に、臭気がどうなるかを比較することにより行うことができる。また、実際に綿衣類や化繊衣類を擬似体臭組成物の塗布対象布にして、被検体による体臭の消臭効果を評価しても良い。
[Evaluation methods]
About the body odor similarity of the pseudo body odor composition of this invention, about the mixed component, it can be performed by determining the reproducibility and similarity about the odor using a special panel of 3-10 persons.
Specifically, the prepared pseudo body odor composition is applied to odor paper, and immediately after the odor paper is smelled, evaluation is performed. The adjusted simulated body odor composition of the present invention can more accurately reproduce various body odors that adhere to and accumulate on clothes that actually exist. Therefore, the pseudo body odor odor adhering to and accumulating on clothes can be evaluated using the pseudo body odor composition of the present invention. Furthermore, by using the simulated body odor composition of the present invention, it is possible to accurately and easily evaluate the masking or deodorizing effect of body odor adhered to and accumulated on clothing. That is, by using the simulated body odor composition of the present invention, it is possible to efficiently screen a substance having a masking action or a deodorizing action on the body odor adhering to and accumulating on clothes.
Evaluation for deodorizing body odor adhering to and accumulating remaining in clothing using the simulated body odor composition of the present invention, that is, a method for evaluating the strength of body odor, for example, prepare a vial with a known capacities, Put a cotton ball, add a specified amount of pseudo body odor composition, sniff the odor, and then compare what happens to the odor when the subject (substance that deodorizes) is added be able to. Moreover, you may evaluate the deodorizing effect of the body odor by a test object by actually making cotton clothing and chemical clothing into the cloth for application of the pseudo body odor composition.
以下、実施例により本発明を更に詳細に説明するが、本発明はこれに限定されるものではない。尚、実施例において、成分配合量は、下記表４の「組成物濃度v/v%」を除きすべて質量％（指定のある場合を除き、純分換算）を示す。 EXAMPLES Hereinafter, although an Example demonstrates this invention further in detail, this invention is not limited to this. In the examples, the component blending amounts are all mass% (in terms of pure amount unless otherwise specified) except for “composition concentration v / v%” in Table 4 below.
［擬似体臭組成物の調製］
・Ａ−１：４‐エチルオクタン酸
・Ｂ−１：３‐メチル‐２‐ヘキセン酸
・Ｃ−１及びＣ−２：下記表１記載の混合物
・比較化合物１：４‐メチル‐３‐ヘキセン酸
・比較化合物２：３‐ヒドロキシ‐３‐メチルヘキサン酸
・溶剤：トリエチルシトレイト（TEC）
上記の成分を、下記表３に記載の濃度になるよう、５０ｍＬのガラス容器内にて順に溶剤に溶解して、組成物とした。
[Preparation of simulated body odor composition]
A-1: 4-ethyloctanoic acid B-1: 3-methyl-2-hexenoic acid C-1 and C-2: mixtures described in Table 1 below
The above components were dissolved in a solvent in order in a 50 mL glass container so that the concentrations shown in Table 3 below were obtained, thereby preparing a composition.
［擬似体臭組成物の臭気評価方法］
調製した各例の擬似体臭組成物について、体臭との類似性及び臭気強度を以下のように評価した。
＜体臭との類似性の評価＞
各擬似体臭組成物をにおい紙につけ、直接、専門パネラー６名でにおい紙のにおいを嗅ぎ評価し、以下の表２に示される評価基準にて総合的に判断して点数を付け、平均点を算出した。
６名の評価平均点：
１．０点〜１．５点未満 → １点
１．５点以上〜２．５点未満 → ２点
２．５点以上〜３．５点未満 → ３点
３．５点以上〜４．５点未満 → ４点
４．５点以上〜５．０点 → ５点
結果を下記表３に示す。
[Odor evaluation method of simulated body odor composition]
About the simulated body odor composition of each prepared example, the similarity with body odor and odor intensity | strength were evaluated as follows.
<Evaluation of similarity to body odor>
Apply each simulated body odor composition to scented paper, and directly evaluate the smell of scented paper with 6 expert panelists, and comprehensively judge and score according to the evaluation criteria shown in Table 2 below. Calculated.
Evaluation average score of 6 people:
1.0 point to less than 1.5 point → 1 point 1.5 point to less than 2.5 point → 2 point 2.5 point to less than 3.5 point → 3 point 3.5 point to 4.5 point Less than points → 4 points 4.5 points or more to 5.0 points → 5 points The results are shown in Table 3 below.
＜臭気強度の評価＞
表３に記載の実施例１の擬似体臭組成物を10倍濃縮したものを準備した。
30mLのバイアル瓶に、綿球（No.14）を一つ入れ、更に、当該擬似体臭組成物の10倍濃縮組成物を、下記表４に記載のとおりトリエチルシトレイト（TEC：トリエチルシトレイト試薬）にて希釈したものを100μL滴下し、密栓して、室温にて1時間放置した。その後、ヘッドスペースの臭気を、専門パネラー３名が以下に示す基準に従って、評価し、協議の上点数を決定した。３点が好ましい。
下記表４に記載の実施例６〜実施例９は、表３に記載の実施例１の擬似体臭組成物の10倍濃縮組成物について、記載の各混合比でＴＥＣで希釈し、その際のバイアル瓶口の臭気強度について試験したものである。結果を下記表４に示す。
（６段階臭気強度の評価基準）
５点：強烈なにおい
４点：強いにおい
３点：楽に感知できるにおい
２点：何のにおいかがわかる弱いにおい（認知閾値濃度）
１点：やっと感知できるにおい（検知閾値濃度）
０点：無臭
<Evaluation of odor intensity>
A 10-fold concentrated product of the simulated body odor composition of Example 1 shown in Table 3 was prepared.
Put one cotton ball (No. 14) into a 30 mL vial, and further add the 10-fold concentrated composition of the simulated body odor composition to triethyl citrate (TEC: triethyl citrate reagent as shown in Table 4 below) 100 μL was added dropwise, and sealed, and left at room temperature for 1 hour. After that, three expert panelists evaluated the odor of the headspace according to the criteria shown below, and decided the score after discussion. Three points are preferred.
Example 6 to Example 9 described in Table 4 below were diluted with TEC at each mixing ratio described above for a 10-fold concentrated composition of the simulated body odor composition of Example 1 described in Table 3, and at that time The odor intensity of the vial mouth was tested. The results are shown in Table 4 below.
(Evaluation criteria for 6-step odor intensity)
5 points: Intense odor 4 points: Strong odor 3 points: Easily perceived odor 2 points: Weak scent to understand what smell (cognitive threshold concentration)
1 point: The smell that can be finally detected (detection threshold concentration)
0 points: odorless
Claims (5)
（Ｂ）３‐メチル‐２‐ヘキセン酸、
（Ｃ）４‐エチルオクタン酸、３‐メチル‐２‐ヘキセン酸及びノナン酸以外の、炭素数３〜１０の低級脂肪酸１種以上、及び
（Ｄ）ノナン酸
を含み、（Ａ）、（Ｂ）、（Ｃ）及び（Ｄ）の質量比が、（Ａ）：（Ｂ）：（Ｃ）：（Ｄ）＝１〜１０：１０〜３０：１〜５：１〜１０である、擬似体臭組成物。 (A) 4-ethyloctanoic acid,
(B) 3-methyl-2-hexenoic acid,
(C) one or more lower fatty acids having 3 to 10 carbon atoms other than 4-ethyloctanoic acid, 3-methyl-2-hexenoic acid and nonanoic acid, and (D) containing nonanoic acid, (A), (B ), (C) and (D) mass ratio of (A) :( B) :( C) :( D) = 1-10: 10-30: 1-5: 1-10 Composition.
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| US8993526B2 (en) * | 2011-02-09 | 2015-03-31 | Chemcom S.A. | Method for counteracting the perception of sweat malodour by decreasing the function of carboxylic acid-binding olfactory receptors |
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