JP2019201631A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019201631A5 JP2019201631A5 JP2019011767A JP2019011767A JP2019201631A5 JP 2019201631 A5 JP2019201631 A5 JP 2019201631A5 JP 2019011767 A JP2019011767 A JP 2019011767A JP 2019011767 A JP2019011767 A JP 2019011767A JP 2019201631 A5 JP2019201631 A5 JP 2019201631A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- population
- disease
- mir
- heart
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023126654A JP7837302B2 (ja) | 2018-01-26 | 2023-08-03 | 治療用途のための微小胞および幹細胞組成物 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/881,693 US20180273906A1 (en) | 2014-04-17 | 2018-01-26 | Microvesicle and stem cell compositions for therapeutic applications |
| US15/881,693 | 2018-01-26 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023126654A Division JP7837302B2 (ja) | 2018-01-26 | 2023-08-03 | 治療用途のための微小胞および幹細胞組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019201631A JP2019201631A (ja) | 2019-11-28 |
| JP2019201631A5 true JP2019201631A5 (https=) | 2022-03-08 |
Family
ID=68725220
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019011767A Pending JP2019201631A (ja) | 2018-01-26 | 2019-01-28 | 治療用微小胞と幹細胞の合成 |
| JP2023126654A Active JP7837302B2 (ja) | 2018-01-26 | 2023-08-03 | 治療用途のための微小胞および幹細胞組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023126654A Active JP7837302B2 (ja) | 2018-01-26 | 2023-08-03 | 治療用途のための微小胞および幹細胞組成物 |
Country Status (2)
| Country | Link |
|---|---|
| US (2) | US20180273906A1 (https=) |
| JP (2) | JP2019201631A (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014197421A1 (en) | 2013-06-05 | 2014-12-11 | Biotime, Inc. | Compositions and methods for induced tissue regeneration in mammalian species |
| US20180273906A1 (en) * | 2014-04-17 | 2018-09-27 | Muhammad Ashraf | Microvesicle and stem cell compositions for therapeutic applications |
| CA3202332A1 (en) | 2015-12-07 | 2017-06-15 | Agex Therapeutics, Inc. | Methods for the re-derivation of diverse pluripotent stem cell-derived brown fat cells |
| KR20180057546A (ko) * | 2016-11-21 | 2018-05-30 | 성균관대학교산학협력단 | 지방줄기세포유래 엑소좀을 유효성분으로 포함하는 간 섬유증 예방 또는 치료용 조성물 |
| CN112334190B (zh) * | 2018-04-30 | 2024-09-20 | 儿童医学中心公司 | 间充质基质细胞外排体及其用途 |
| CN109266603A (zh) * | 2018-08-29 | 2019-01-25 | 浙江大学 | 一种提高心梗疗效的外泌体及应用 |
| US12508325B2 (en) | 2018-12-20 | 2025-12-30 | Ohio State Innovation Foundation | Compositions and methods for reprogramming diseased musculoskeletal cells |
| WO2020132161A1 (en) * | 2018-12-21 | 2020-06-25 | The Regents Of The University Of California | Compositions and methods for treating hearing loss |
| CN114207110A (zh) * | 2019-03-28 | 2022-03-18 | Agex治疗公司 | 使用细胞外囊泡诱导的组织再生 |
| KR20220039647A (ko) * | 2019-04-03 | 2022-03-29 | 더 존스 홉킨스 유니버시티 | 골격근 줄기세포 생성 및 질환 치료를 위한 방법, 조성물 및 키트 |
| US20220233604A1 (en) * | 2019-05-15 | 2022-07-28 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for treating cardiomyocytes |
| CN110257333A (zh) * | 2019-05-27 | 2019-09-20 | 江苏大学 | 一种神经干细胞微囊泡及其应用 |
| CN110724665A (zh) * | 2019-11-21 | 2020-01-24 | 西安外事学院 | 一种iPS细胞培养上清液及其制备方法和应用 |
| WO2021114164A1 (zh) * | 2019-12-12 | 2021-06-17 | 中国科学院深圳先进技术研究院 | 一种外泌体及其制备方法及应用 |
| CN115175986B (zh) | 2020-02-10 | 2024-11-08 | 公立大学法人名古屋市立大学 | 用于诱导多能干细胞向脑毛细血管内皮样细胞分化的涂布剂及其利用 |
| CN111961645A (zh) * | 2020-09-01 | 2020-11-20 | 杭州优渡生物科技有限公司 | 一种高效扩增人表皮成纤维细胞的培养基 |
| CN116806257A (zh) * | 2020-10-14 | 2023-09-26 | 达芬奇环球有限公司 | 心肌干细胞/心肌前体细胞的制备方法及心肌纤维化抑制方法 |
| EP4247938A4 (en) * | 2020-11-18 | 2024-05-15 | FUJIFILM Corporation | Generation of secretome-containing compositions, and methods of using and analyzing the same |
| CN112608972B (zh) * | 2020-12-21 | 2021-09-10 | 广东源心再生医学有限公司 | Myog基因作为靶点在制备治疗心肌细胞凋亡相关的心血管疾病的药物中的应用 |
| CN114645021A (zh) * | 2020-12-21 | 2022-06-21 | 未来智人再生医学研究院(广州)有限公司 | 一种表达靶向cd47抑制因子的多能干细胞及其衍生物与应用 |
| CN114657130A (zh) * | 2020-12-22 | 2022-06-24 | 未来智人再生医学研究院(广州)有限公司 | 一种表达vegf-a靶向抑制因子的多能干细胞及其衍生物与应用 |
| CN113209135B (zh) * | 2021-04-23 | 2023-06-13 | 奥启(深圳)生物科技有限公司 | 一种用于延缓皮肤衰老的间充质干细胞外泌体制剂 |
| CN113322226A (zh) * | 2021-06-28 | 2021-08-31 | 华南理工大学 | 三维培养胚胎干细胞来源的外泌体及在制备治疗肝纤维化药物的应用 |
| JPWO2023079655A1 (https=) * | 2021-11-04 | 2023-05-11 | ||
| WO2023136313A1 (ja) * | 2022-01-14 | 2023-07-20 | 国立大学法人大阪大学 | 肝機能障害を処置するための組成物 |
| WO2023154466A1 (en) * | 2022-02-11 | 2023-08-17 | The University Of North Carolina At Chapel Hill | Arylbenzoisoxazole compounds as ip6k and ipmk inhibitors and methods of use thereof |
| KR102816689B1 (ko) * | 2022-03-29 | 2025-06-02 | 박동선 | Tsg101 단백질을 암호화하는 폴리뉴클레오티드가 도입된 줄기세포 및 이의 용도 |
| PL443827A1 (pl) * | 2023-02-18 | 2024-08-19 | Uniwersytet Jagielloński | Sposób otrzymywania pęcherzyków zewnątrzkomórkowych (EVs) pochodzących z indukowanych pluripotencjalnych komórek macierzystych (iPSC) oraz ich zastosowanie |
| WO2025117472A1 (en) * | 2023-11-30 | 2025-06-05 | Immorta Bio, Inc. | Treatment of heart failure using pluripotent stem cell derived cardiomyocytes and derivatives thereof |
| WO2025160404A1 (en) * | 2024-01-26 | 2025-07-31 | FUJIFILM Cellular Dynamics, Inc. | Generation of secretome-containing compositions, and methods of using and analyzing the same |
| WO2025247999A1 (en) * | 2024-05-30 | 2025-12-04 | Conveyxo | Method for the production of extracellular vesicles loaded with a molecule of interest and composition comprising such extracellular vesicles |
| EP4656187A1 (en) * | 2024-05-30 | 2025-12-03 | ConvEyXo | Method for the production of extracellular vesicles loaded with a molecule of interest and composition comprising such extracellular vesicles |
| CN120131648B (zh) * | 2025-03-06 | 2025-11-25 | 上海市重大传染病和生物安全研究院 | 一种hiv-1潜伏感染激活剂、药物及用途 |
| CN120437124A (zh) * | 2025-06-10 | 2025-08-08 | 南方医科大学 | 小分子isx-9在促进间充质干细胞成骨分化和骨损伤再生修复中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10443044B2 (en) | 2014-04-17 | 2019-10-15 | Ips Heart | Generating cardiac progenitor cells from pluripotent stem cells using isoxazole or isoxazole like compounds |
| US20150297638A1 (en) * | 2014-04-17 | 2015-10-22 | Muhammad Ashraf | Chemically induced pluripotent stem cells for safe therapeutic applications |
| US20180273906A1 (en) | 2014-04-17 | 2018-09-27 | Muhammad Ashraf | Microvesicle and stem cell compositions for therapeutic applications |
| WO2016108288A1 (ja) | 2014-12-29 | 2016-07-07 | 国立大学法人京都大学 | 骨格筋前駆細胞の製造方法 |
| WO2017196175A1 (en) | 2016-05-12 | 2017-11-16 | Erasmus University Medical Center Rotterdam | A method for culturing myogenic cells, cultures obtained therefrom, screening methods, and cell culture medium. |
-
2018
- 2018-01-26 US US15/881,693 patent/US20180273906A1/en active Pending
-
2019
- 2019-01-28 JP JP2019011767A patent/JP2019201631A/ja active Pending
-
2020
- 2020-02-19 US US16/795,217 patent/US20210054344A1/en not_active Abandoned
-
2023
- 2023-08-03 JP JP2023126654A patent/JP7837302B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019201631A5 (https=) | ||
| JP7837302B2 (ja) | 治療用途のための微小胞および幹細胞組成物 | |
| Burridge et al. | Genetic and epigenetic regulation of human cardiac reprogramming and differentiation in regenerative medicine | |
| Sadahiro et al. | Direct cardiac reprogramming: progress and challenges in basic biology and clinical applications | |
| Salani et al. | Generation of skeletal muscle cells from embryonic and induced pluripotent stem cells as an in vitro model and for therapy of muscular dystrophies | |
| Jiang et al. | CRISPR activation of endogenous genes reprograms fibroblasts into cardiovascular progenitor cells for myocardial infarction therapy | |
| AU2017326535B2 (en) | Cell-specific expression of modrna | |
| US10144915B2 (en) | Reprogramming fibroblasts into cardiomyocytes | |
| TWI484033B (zh) | 培養幹細胞之方法及套組 | |
| WO2003080801A2 (en) | Adipose stromal stem cells for tissue and vascular modification | |
| Hassan et al. | Concise review: skeletal muscle stem cells and cardiac lineage: potential for heart repair | |
| Li et al. | Mending a faltering heart | |
| US10443044B2 (en) | Generating cardiac progenitor cells from pluripotent stem cells using isoxazole or isoxazole like compounds | |
| Gao et al. | Differentiation and application of human pluripotent stem cells derived cardiovascular cells for treatment of heart diseases: Promises and challenges | |
| JP7723606B2 (ja) | 幹細胞由来心筋細胞への抗不整脈剤の適用およびその使用 | |
| Ye et al. | Cardiac stem cell therapy: review of the native cardiac progenitor cells and future direction | |
| KR20240125943A (ko) | 신경능 세포의 배양 방법 및 제조 방법 | |
| Jin et al. | Enhanced differentiation of human pluripotent stem cells into cardiomyocytes by bacteria-mediated transcription factors delivery | |
| Schoenhard et al. | Stem cell therapy: pieces of the puzzle | |
| Maas et al. | Harnessing developmental cues for cardiomyocyte production | |
| Eom et al. | Effective myotube formation in human adipose tissue-derived stem cells expressing dystrophin and myosin heavy chain by cellular fusion with mouse C2C12 myoblasts | |
| US9155765B2 (en) | Establishment of patient- or person-specific cardiac myocyte cell lines from human induced pluripotent stem cells (iPSCs) | |
| CN110241136A (zh) | 促进基因编辑的小分子化合物及其应用 | |
| JP2023058639A (ja) | 分化細胞の品質改善方法 | |
| Bonavida et al. | Novel Approaches to Program Cells to Differentiate into Cardiomyocytes in Myocardial Regeneration |