JP2018538280A5 - - Google Patents
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- Publication number
- JP2018538280A5 JP2018538280A5 JP2018526676A JP2018526676A JP2018538280A5 JP 2018538280 A5 JP2018538280 A5 JP 2018538280A5 JP 2018526676 A JP2018526676 A JP 2018526676A JP 2018526676 A JP2018526676 A JP 2018526676A JP 2018538280 A5 JP2018538280 A5 JP 2018538280A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- tfr
- agent
- subject
- cytokine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 210000004027 cell Anatomy 0.000 claims 22
- 239000003795 chemical substances by application Substances 0.000 claims 15
- 108090000695 Cytokines Proteins 0.000 claims 13
- 102000004127 Cytokines Human genes 0.000 claims 13
- 239000000203 mixture Substances 0.000 claims 11
- 239000002671 adjuvant Substances 0.000 claims 6
- 108090001005 Interleukin-6 Proteins 0.000 claims 5
- 230000005875 antibody response Effects 0.000 claims 5
- 230000005965 immune activity Effects 0.000 claims 5
- 230000001681 protective effect Effects 0.000 claims 5
- 230000016784 immunoglobulin production Effects 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 210000005259 peripheral blood Anatomy 0.000 claims 4
- 239000011886 peripheral blood Substances 0.000 claims 4
- 229960005486 vaccine Drugs 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 230000001629 suppression Effects 0.000 claims 3
- 208000035143 Bacterial infection Diseases 0.000 claims 2
- 206010017533 Fungal infection Diseases 0.000 claims 2
- 208000031888 Mycoses Diseases 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 208000036142 Viral infection Diseases 0.000 claims 2
- 208000022362 bacterial infectious disease Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 108010046926 intraovarian peptides Proteins 0.000 claims 2
- 230000001404 mediated effect Effects 0.000 claims 2
- 230000001717 pathogenic effect Effects 0.000 claims 2
- 210000000130 stem cell Anatomy 0.000 claims 2
- 230000009385 viral infection Effects 0.000 claims 2
- 230000033228 biological regulation Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 230000001900 immune effect Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 230000008506 pathogenesis Effects 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 230000003827 upregulation Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562258876P | 2015-11-23 | 2015-11-23 | |
| US62/258,876 | 2015-11-23 | ||
| US201662300339P | 2016-02-26 | 2016-02-26 | |
| US62/300,339 | 2016-02-26 | ||
| PCT/US2016/063604 WO2017091729A1 (en) | 2015-11-23 | 2016-11-23 | Compositions and methods for modulating an immune response |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018538280A JP2018538280A (ja) | 2018-12-27 |
| JP2018538280A5 true JP2018538280A5 (enExample) | 2020-01-09 |
Family
ID=58763732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018526676A Abandoned JP2018538280A (ja) | 2015-11-23 | 2016-11-23 | 免疫応答を調節するための組成物及び方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11028364B2 (enExample) |
| EP (1) | EP3380197A4 (enExample) |
| JP (1) | JP2018538280A (enExample) |
| AU (1) | AU2016361569A1 (enExample) |
| CA (1) | CA3005899A1 (enExample) |
| WO (1) | WO2017091729A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2531216B1 (en) * | 2010-02-04 | 2019-03-27 | The Trustees Of The University Of Pennsylvania | Icos critically regulates the expansion and function of inflammatory human th17 cells |
| CN117425668A (zh) * | 2021-03-16 | 2024-01-19 | 国立大学法人大阪大学 | SARS-CoV-2病毒特异性滤泡辅助性T细胞Tfh |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010003002A2 (en) * | 2008-07-02 | 2010-01-07 | Board Of Regents, The University Of Texas System | Modulation of follicular helper t cells |
| WO2014074852A1 (en) * | 2012-11-09 | 2014-05-15 | President And Fellows Of Harvard College | Compositions and methods for modulating an immune response |
-
2016
- 2016-11-23 EP EP16869273.9A patent/EP3380197A4/en not_active Withdrawn
- 2016-11-23 AU AU2016361569A patent/AU2016361569A1/en not_active Abandoned
- 2016-11-23 US US15/778,524 patent/US11028364B2/en active Active
- 2016-11-23 JP JP2018526676A patent/JP2018538280A/ja not_active Abandoned
- 2016-11-23 CA CA3005899A patent/CA3005899A1/en not_active Abandoned
- 2016-11-23 WO PCT/US2016/063604 patent/WO2017091729A1/en not_active Ceased
-
2021
- 2021-05-07 US US17/314,438 patent/US20220010275A1/en not_active Abandoned
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