JP2015526469A5 - - Google Patents
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- Publication number
- JP2015526469A5 JP2015526469A5 JP2015528558A JP2015528558A JP2015526469A5 JP 2015526469 A5 JP2015526469 A5 JP 2015526469A5 JP 2015528558 A JP2015528558 A JP 2015528558A JP 2015528558 A JP2015528558 A JP 2015528558A JP 2015526469 A5 JP2015526469 A5 JP 2015526469A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- use according
- placenta
- heterologous
- adjuvant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 17
- 210000002826 placenta Anatomy 0.000 claims 6
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 239000002671 adjuvant Substances 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 4
- 206010061598 Immunodeficiency Diseases 0.000 claims 3
- 208000029462 Immunodeficiency disease Diseases 0.000 claims 3
- 101710158668 Placental protein Proteins 0.000 claims 3
- 102000008217 Pregnancy Proteins Human genes 0.000 claims 3
- 210000004443 dendritic cell Anatomy 0.000 claims 3
- 230000003053 immunization Effects 0.000 claims 3
- 230000007813 immunodeficiency Effects 0.000 claims 3
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 claims 2
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims 2
- 108010065805 Interleukin-12 Proteins 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 238000002649 immunization Methods 0.000 claims 2
- 239000012528 membrane Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 238000011282 treatment Methods 0.000 claims 2
- 210000002993 trophoblast Anatomy 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 1
- 102100035875 C-C chemokine receptor type 5 Human genes 0.000 claims 1
- 101710149870 C-C chemokine receptor type 5 Proteins 0.000 claims 1
- 239000012275 CTLA-4 inhibitor Substances 0.000 claims 1
- 229940045513 CTLA4 antagonist Drugs 0.000 claims 1
- 206010008874 Chronic Fatigue Syndrome Diseases 0.000 claims 1
- 229940046168 CpG oligodeoxynucleotide Drugs 0.000 claims 1
- YVGGHNCTFXOJCH-UHFFFAOYSA-N DDT Chemical compound C1=CC(Cl)=CC=C1C(C(Cl)(Cl)Cl)C1=CC=C(Cl)C=C1 YVGGHNCTFXOJCH-UHFFFAOYSA-N 0.000 claims 1
- 108010027992 HSP70 Heat-Shock Proteins Proteins 0.000 claims 1
- 102000018932 HSP70 Heat-Shock Proteins Human genes 0.000 claims 1
- 241000725303 Human immunodeficiency virus Species 0.000 claims 1
- 206010062016 Immunosuppression Diseases 0.000 claims 1
- 102100037850 Interferon gamma Human genes 0.000 claims 1
- 102000006992 Interferon-alpha Human genes 0.000 claims 1
- 108010047761 Interferon-alpha Proteins 0.000 claims 1
- 108010074328 Interferon-gamma Proteins 0.000 claims 1
- 108010002350 Interleukin-2 Proteins 0.000 claims 1
- 108010006519 Molecular Chaperones Proteins 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 230000000735 allogeneic effect Effects 0.000 claims 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims 1
- 239000013592 cell lysate Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 210000002889 endothelial cell Anatomy 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000036039 immunity Effects 0.000 claims 1
- 230000003308 immunostimulating effect Effects 0.000 claims 1
- 230000001506 immunosuppresive effect Effects 0.000 claims 1
- 239000000411 inducer Substances 0.000 claims 1
- 239000003446 ligand Substances 0.000 claims 1
- 208000029766 myalgic encephalomeyelitis/chronic fatigue syndrome Diseases 0.000 claims 1
- OHDXDNUPVVYWOV-UHFFFAOYSA-N n-methyl-1-(2-naphthalen-1-ylsulfanylphenyl)methanamine Chemical compound CNCC1=CC=CC=C1SC1=CC=CC2=CC=CC=C12 OHDXDNUPVVYWOV-UHFFFAOYSA-N 0.000 claims 1
- 230000003169 placental effect Effects 0.000 claims 1
- 230000003389 potentiating effect Effects 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 239000000018 receptor agonist Substances 0.000 claims 1
- 229940044601 receptor agonist Drugs 0.000 claims 1
- 230000001629 suppression Effects 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 210000004881 tumor cell Anatomy 0.000 claims 1
- 238000002255 vaccination Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261691187P | 2012-08-20 | 2012-08-20 | |
| US61/691,187 | 2012-08-20 | ||
| PCT/US2013/055632 WO2014031553A1 (en) | 2012-08-20 | 2013-08-19 | Placental vaccination therapy for cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015526469A JP2015526469A (ja) | 2015-09-10 |
| JP2015526469A5 true JP2015526469A5 (enExample) | 2016-10-06 |
Family
ID=50150330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015528558A Pending JP2015526469A (ja) | 2012-08-20 | 2013-08-19 | 癌に対する胎盤ワクチン接種療法 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US20150216957A1 (enExample) |
| EP (1) | EP2925332A4 (enExample) |
| JP (1) | JP2015526469A (enExample) |
| WO (1) | WO2014031553A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015142855A1 (en) * | 2014-03-17 | 2015-09-24 | University Of Virginia Patent Foundation | Compositions and methods for treating retinopathy |
| WO2015168503A1 (en) * | 2014-05-02 | 2015-11-05 | Batu Biologics | Compositions and means for induction of tumor immunity |
| US11298380B2 (en) * | 2018-01-02 | 2022-04-12 | Khloris Biosciences, Inc. | IPSC-based vaccine as a prophylactic and therapeutic treatment for cancer |
| US11026980B1 (en) | 2018-02-26 | 2021-06-08 | Triad Life Sciences, Inc. | Flowable birth tissue composition and related methods |
| CN114585373B (zh) | 2019-05-06 | 2025-07-22 | 艾克塞利瑞提德生物技术公司 | 前体调节性细胞滋养层细胞及其用途 |
| JP7787510B2 (ja) * | 2021-03-12 | 2025-12-17 | ドクタープロラボジャパン株式会社 | プラセンタ抽出物の正常細胞増殖ヒト卵巣がん細胞増殖抑制用製剤の製造のための使用方法及び正常細胞増殖ヒト卵巣がん細胞増殖抑制用製剤の製造方法 |
| CN115873790B (zh) * | 2021-09-27 | 2026-01-02 | 金涌长生医学生物科技股份有限公司 | 一种蜕膜胎盘间充质干细胞及其在制备促进血管新生药物组合物中的用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9107305D0 (en) | 1991-04-08 | 1991-05-22 | Unilever Plc | Probiotic |
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US6861053B1 (en) | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
| US6090622A (en) | 1997-03-31 | 2000-07-18 | The Johns Hopkins School Of Medicine | Human embryonic pluripotent germ cells |
| ID29150A (id) | 1999-01-15 | 2001-08-02 | Entpr Ireland Cs | Penggunaan lactobacillus salivarius |
| IT1318405B1 (it) * | 2000-03-17 | 2003-08-25 | Piermario Biava | Composizione antitumorale costituita da una frazione di utero gravidoo di placenta di mammiferi. |
| TWI310686B (enExample) * | 2002-10-18 | 2009-06-11 | You Ru Qian | |
| WO2008002005A1 (en) * | 2006-06-27 | 2008-01-03 | Choongangbiotech Co., Ltd. | A method for preparing pig placental extract to use as a feed additive and use thereof |
| JP2009035527A (ja) * | 2007-08-01 | 2009-02-19 | Snowden Co Ltd | 動物胎盤抽出物よりなるアンドロゲン受容体結合阻害剤 |
| WO2012018145A2 (ja) * | 2010-08-05 | 2012-02-09 | 株式会社日本生物製剤 | Ｑｏｌ改善剤 |
-
2013
- 2013-08-19 WO PCT/US2013/055632 patent/WO2014031553A1/en not_active Ceased
- 2013-08-19 US US14/422,644 patent/US20150216957A1/en not_active Abandoned
- 2013-08-19 JP JP2015528558A patent/JP2015526469A/ja active Pending
- 2013-08-19 EP EP13831444.8A patent/EP2925332A4/en not_active Withdrawn
-
2017
- 2017-11-02 US US15/801,953 patent/US20180125955A1/en not_active Abandoned
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