JP2018534942A - 単一分子対照 - Google Patents
単一分子対照 Download PDFInfo
- Publication number
- JP2018534942A JP2018534942A JP2018527241A JP2018527241A JP2018534942A JP 2018534942 A JP2018534942 A JP 2018534942A JP 2018527241 A JP2018527241 A JP 2018527241A JP 2018527241 A JP2018527241 A JP 2018527241A JP 2018534942 A JP2018534942 A JP 2018534942A
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- region
- acid molecule
- cassette
- solid support
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CCCC(C(C1)C1(C)C1CC1)C(CC(C)C1)=C[C@@](C2)[C@@]12C(C1)(C2)[C@@]1(C1)[C@@]2(C2CC2)C1c1ccc(CC(CC(C)C2)CC2C(CC2)C(C(C)C(*)*)C2C(C)C)cc1 Chemical compound CCCC(C(C1)C1(C)C1CC1)C(CC(C)C1)=C[C@@](C2)[C@@]12C(C1)(C2)[C@@]1(C1)[C@@]2(C2CC2)C1c1ccc(CC(CC(C)C2)CC2C(CC2)C(C(C)C(*)*)C2C(C)C)cc1 0.000 description 3
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1520883.8 | 2015-11-26 | ||
| GBGB1520883.8A GB201520883D0 (en) | 2015-11-26 | 2015-11-26 | Single molecule controls |
| GB1605055.1 | 2016-03-24 | ||
| GBGB1605055.1A GB201605055D0 (en) | 2016-03-24 | 2016-03-24 | Single molecule controls |
| PCT/GB2016/053649 WO2017089767A1 (en) | 2015-11-26 | 2016-11-23 | Single molecule controls |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018534942A true JP2018534942A (ja) | 2018-11-29 |
| JP2018534942A5 JP2018534942A5 (enExample) | 2019-10-03 |
Family
ID=57442739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018527241A Pending JP2018534942A (ja) | 2015-11-26 | 2016-11-23 | 単一分子対照 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20210285035A1 (enExample) |
| EP (1) | EP3380634A1 (enExample) |
| JP (1) | JP2018534942A (enExample) |
| CN (1) | CN108699597A (enExample) |
| WO (1) | WO2017089767A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015217208B2 (en) | 2014-02-11 | 2018-08-30 | The Regents Of The University Of Colorado, A Body Corporate | CRISPR enabled multiplexed genome engineering |
| DK3474669T3 (da) | 2016-06-24 | 2022-06-27 | Univ Colorado Regents | Fremgangsmåde til generering af stregkodede kombinatoriske biblioteker |
| US10011849B1 (en) | 2017-06-23 | 2018-07-03 | Inscripta, Inc. | Nucleic acid-guided nucleases |
| US9982279B1 (en) | 2017-06-23 | 2018-05-29 | Inscripta, Inc. | Nucleic acid-guided nucleases |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008508901A (ja) * | 2004-08-09 | 2008-03-27 | ジェネレイション バイオテック リミテッド ライアビリティ カンパニー | 核酸の単離および増幅方法 |
| WO2011014811A1 (en) * | 2009-07-31 | 2011-02-03 | Ibis Biosciences, Inc. | Capture primers and capture sequence linked solid supports for molecular diagnostic tests |
| WO2012102329A1 (ja) * | 2011-01-26 | 2012-08-02 | 株式会社日立ハイテクノロジーズ | 単分子プロ-ブ核酸付微粒子、その製造方法、それを用いた核酸分析方法、核酸分析用デバイス及び核酸分析装置 |
| JP5453132B2 (ja) * | 2009-02-25 | 2014-03-26 | エフ.ホフマン−ラ ロシュ アーゲー | ハイスループット核酸分析のためのビーズ |
| JP2014532396A (ja) * | 2011-10-28 | 2014-12-08 | アルベルト−ルートヴィヒ−ウニベルシタット フライブルク | アプタマーを同定する方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020172965A1 (en) * | 1996-12-13 | 2002-11-21 | Arcaris, Inc. | Methods for measuring relative amounts of nucleic acids in a complex mixture and retrieval of specific sequences therefrom |
| US5888740A (en) * | 1997-09-19 | 1999-03-30 | Genaco Biomedical Products, Inc. | Detection of aneuploidy and gene deletion by PCR-based gene- dose co-amplification of chromosome specific sequences with synthetic sequences with synthetic internal controls |
| KR20050010902A (ko) * | 2002-06-12 | 2005-01-28 | 카이론 코포레이션 | A형 간염 바이러스 핵산의 포획, 검출 및 정량을 위한올리고뉴클레오티드의 동정방법 |
| US20080108515A1 (en) * | 2004-02-10 | 2008-05-08 | Gormley Niall A | Arrayed polynucleotides |
| CN101067156A (zh) * | 2007-05-18 | 2007-11-07 | 中国人民解放军第三军医大学第一附属医院 | 一种基于选择性探针的多重pcr方法及其应用 |
| CN101821619B (zh) * | 2007-09-07 | 2015-02-11 | 弗卢丁公司 | 拷贝数变化确定、方法和系统 |
-
2016
- 2016-11-23 WO PCT/GB2016/053649 patent/WO2017089767A1/en not_active Ceased
- 2016-11-23 US US15/779,274 patent/US20210285035A1/en not_active Abandoned
- 2016-11-23 EP EP16804851.0A patent/EP3380634A1/en not_active Withdrawn
- 2016-11-23 CN CN201680080249.5A patent/CN108699597A/zh active Pending
- 2016-11-23 JP JP2018527241A patent/JP2018534942A/ja active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008508901A (ja) * | 2004-08-09 | 2008-03-27 | ジェネレイション バイオテック リミテッド ライアビリティ カンパニー | 核酸の単離および増幅方法 |
| JP5453132B2 (ja) * | 2009-02-25 | 2014-03-26 | エフ.ホフマン−ラ ロシュ アーゲー | ハイスループット核酸分析のためのビーズ |
| WO2011014811A1 (en) * | 2009-07-31 | 2011-02-03 | Ibis Biosciences, Inc. | Capture primers and capture sequence linked solid supports for molecular diagnostic tests |
| WO2012102329A1 (ja) * | 2011-01-26 | 2012-08-02 | 株式会社日立ハイテクノロジーズ | 単分子プロ-ブ核酸付微粒子、その製造方法、それを用いた核酸分析方法、核酸分析用デバイス及び核酸分析装置 |
| JP2014532396A (ja) * | 2011-10-28 | 2014-12-08 | アルベルト−ルートヴィヒ−ウニベルシタット フライブルク | アプタマーを同定する方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20210285035A1 (en) | 2021-09-16 |
| CN108699597A (zh) | 2018-10-23 |
| EP3380634A1 (en) | 2018-10-03 |
| WO2017089767A1 (en) | 2017-06-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Daher et al. | Recombinase polymerase amplification for diagnostic applications | |
| US11479816B2 (en) | Nucleotide sequence generation by barcode bead-colocalization in partitions | |
| CN104854246B (zh) | 无限制酶的靶标富集 | |
| US7914986B2 (en) | Detection of amplicon contamination during PCR exhibiting two different annealing temperatures | |
| EP3784798A1 (en) | Enrichment of dna comprising target sequence of interest | |
| CN111936635B (zh) | 用于单分子测序的单链环状dna模板的产生 | |
| EP3174997B1 (en) | Method for selecting a target nucleic acid sequence | |
| JP6906504B2 (ja) | 短いホモポリマー反復の改良された検出 | |
| JP2018534942A (ja) | 単一分子対照 | |
| JP2016520326A (ja) | マルチプレックス配列決定のための分子バーコード化 | |
| Song et al. | Self-priming hairpin-utilized isothermal amplification enabling ultrasensitive nucleic acid detection | |
| JP2022145606A (ja) | 核酸の正確な並行定量のための高感度な方法 | |
| JP2022110152A (ja) | 診断方法及び組成物 | |
| JP3789317B2 (ja) | 特定の核酸を検出定量するための等長プライマー伸長法およびキット | |
| KR20140071968A (ko) | Pcr에 의한 미생물 dna 검출 방법, 이를 위한 시스템 및 조성물 | |
| US20180073063A1 (en) | Reusable microarray compositions and methods | |
| TWI816299B (zh) | 一種數位化分析樣品中核酸之方法 | |
| JP2024523655A (ja) | 核酸分析のための方法および組成物 | |
| CA3217131A1 (en) | Amplification techniques for nucleic acid characterization | |
| JP6202455B2 (ja) | 標的核酸の検出方法 | |
| JP7762690B2 (ja) | 変異核酸の正確な並行定量するための高感度方法 | |
| WO2025078657A1 (en) | Amplification-free target enrichment workflow for direct detection of nucleic acid modifications | |
| TW202526036A (zh) | 準確地平行定量核酸的高靈敏度方法 | |
| Hyman | Integrating DNA Logic Circuits and Isothermal Amplification Methods: Novel Tools for Single-Cell Transcriptional Profiling and Diagnostics | |
| US20160122810A1 (en) | Systems and methods for nucleic acid capture |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20190820 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20190820 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20200527 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20200929 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20210506 |