JP2018532408A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018532408A5 JP2018532408A5 JP2018520385A JP2018520385A JP2018532408A5 JP 2018532408 A5 JP2018532408 A5 JP 2018532408A5 JP 2018520385 A JP2018520385 A JP 2018520385A JP 2018520385 A JP2018520385 A JP 2018520385A JP 2018532408 A5 JP2018532408 A5 JP 2018532408A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- host cell
- poly
- gene editing
- editing system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562187942P | 2015-07-02 | 2015-07-02 | |
| US62/187,942 | 2015-07-02 | ||
| US201662322346P | 2016-04-14 | 2016-04-14 | |
| US62/322,346 | 2016-04-14 | ||
| US15/199,021 US20170000743A1 (en) | 2015-07-02 | 2016-06-30 | Compositions and Methods for Delivery of Gene Editing Tools Using Polymeric Vesicles |
| US15/199,021 | 2016-06-30 | ||
| PCT/US2016/040673 WO2017004509A1 (en) | 2015-07-02 | 2016-07-01 | Compositions and methods for delivery of gene editing tools using polymeric vesicles |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019105213A Division JP2019165745A (ja) | 2015-07-02 | 2019-06-05 | ポリマーベシクルを使用する遺伝子編集ツールを送達するための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018532408A JP2018532408A (ja) | 2018-11-08 |
| JP2018532408A5 true JP2018532408A5 (https=) | 2019-07-11 |
| JP6993966B2 JP6993966B2 (ja) | 2022-02-04 |
Family
ID=57609243
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018520385A Active JP6993966B2 (ja) | 2015-07-02 | 2016-07-01 | ポリマーベシクルを使用する遺伝子編集ツールを送達するための組成物および方法 |
| JP2019105213A Pending JP2019165745A (ja) | 2015-07-02 | 2019-06-05 | ポリマーベシクルを使用する遺伝子編集ツールを送達するための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019105213A Pending JP2019165745A (ja) | 2015-07-02 | 2019-06-05 | ポリマーベシクルを使用する遺伝子編集ツールを送達するための組成物および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20170000743A1 (https=) |
| EP (1) | EP3317414A4 (https=) |
| JP (2) | JP6993966B2 (https=) |
| CN (1) | CN108699563A (https=) |
| AU (1) | AU2016288237B2 (https=) |
| CA (1) | CA2991109A1 (https=) |
| HK (1) | HK1255209A1 (https=) |
| WO (1) | WO2017004509A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10456452B2 (en) | 2015-07-02 | 2019-10-29 | Poseida Therapeutics, Inc. | Compositions and methods for improved encapsulation of functional proteins in polymeric vesicles |
| US11213594B2 (en) | 2016-04-29 | 2022-01-04 | Poseida Therapeutics, Inc. | Poly(histidine)-based micelles for complexation and delivery of proteins and nucleic acids |
| CA3036926C (en) | 2016-09-30 | 2022-05-31 | Poseida Therapeutics, Inc. | Modified stem cell memory t cells, methods of making and methods of using same |
| US20190119636A1 (en) | 2017-10-23 | 2019-04-25 | Poseida Therapeutics, Inc. | Modified stem cell memory t cells, methods of making and methods of using same |
| ES3051391T3 (en) | 2016-10-06 | 2025-12-29 | Poseida Therapeutics Inc | Inducible caspases and methods for use |
| JP2020523383A (ja) | 2017-06-14 | 2020-08-06 | ダナ−ファーバー キャンサー インスティテュート，インコーポレイテッド | Ｂ細胞成熟抗原（ｂｃｍａ）指向性ナノ粒子 |
| WO2018232356A1 (en) | 2017-06-15 | 2018-12-20 | The Regents Of The University Of California | Targeted non-viral dna insertions |
| US10329543B2 (en) | 2017-10-23 | 2019-06-25 | Poseida Therapeutics, Inc. | Modified stem cell memory T cells, methods of making and methods of using same |
| JP7101419B2 (ja) | 2017-10-27 | 2022-07-15 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 内因性ｔ細胞受容体の標的置換 |
| CA3124103A1 (en) | 2018-12-20 | 2020-06-25 | Poseida Therapeutics, Inc. | Nanotransposon compositions and methods of use |
| US20220372105A1 (en) | 2019-09-05 | 2022-11-24 | Poseida Therapeutics, Inc. | Allogeneic cell compositions and methods of use |
| AU2020407235A1 (en) | 2019-12-20 | 2022-07-07 | Poseida Therapeutics, Inc. | Anti-MUC1 compositions and methods of use |
| WO2021183795A1 (en) | 2020-03-11 | 2021-09-16 | Poseida Therapeutics, Inc. | Chimeric stimulatory receptors and methods of use in t cell activation and differentiation |
| GB202004254D0 (en) | 2020-03-24 | 2020-05-06 | Puridify Ltd | Characterization of gene therapy vectors |
| EP4298205A1 (en) | 2021-02-23 | 2024-01-03 | Poseida Therapeutics, Inc. | Genetically modified induced pluripotent stem cells and methods of use thereof |
| CN117355607A (zh) * | 2021-04-13 | 2024-01-05 | 阿森纳生物科学公司 | 非病毒同源性介导的末端连接 |
| EP4413141A1 (en) | 2021-10-04 | 2024-08-14 | Poseida Therapeutics, Inc. | Transposon compositions and methods of use thereof |
| JP2024537991A (ja) | 2021-10-14 | 2024-10-18 | アーセナル バイオサイエンシズ インコーポレイテッド | 共発現されるｓｈＲＮＡと論理ゲートシステムとを有する免疫細胞 |
| EP4482967A1 (en) | 2022-02-23 | 2025-01-01 | Poseida Therapeutics, Inc. | Genetically modified cells and methods of use thereof |
| WO2023193665A1 (zh) * | 2022-04-07 | 2023-10-12 | 威海纽兰生物科技有限公司 | 基于细胞外囊泡酯酶响应药物递送载体及其制备方法和用途 |
| EP4646189A1 (en) * | 2023-01-06 | 2025-11-12 | Vianautis Bio Limited | Polymersomes for delivery of nucleic acid cargoes |
| EP4669746A1 (en) | 2023-02-21 | 2025-12-31 | Poseida Therapeutics, Inc. | COMPOSITIONS AND GENOMIC EDITING PROCESSES |
| KR20250166122A (ko) | 2023-02-21 | 2025-11-27 | 포세이다 테라퓨틱스, 인크. | 게놈 편집을 위한 조성물 및 방법 |
| CN121335979A (zh) | 2023-05-17 | 2026-01-13 | 波西达治疗公司 | 靶向hbg1和hbg2的组合物及其使用方法 |
| WO2025096980A1 (en) | 2023-11-02 | 2025-05-08 | Poseida Therapeutics, Inc. | Compositions targeting klkb1 and methods of use thereof |
| WO2025221789A1 (en) | 2024-04-16 | 2025-10-23 | Poseida Therapeutics, Inc. | Compositions and methods for use in car/tcr cell therapies |
| WO2026080393A1 (en) | 2024-10-07 | 2026-04-16 | Poseida Therapeutics, Inc. | Compositions and methods for use in car cell therapies |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001089579A2 (en) * | 2000-05-19 | 2001-11-29 | Regents Of The University Of Minnesota | Composition for delivery of compounds to cells |
| US20040265835A1 (en) * | 2003-06-30 | 2004-12-30 | Lemaster David M. | Method of sorting vesicle-entrapped, coupled nucleic acid-protein displays |
| CA2756670A1 (en) * | 2009-03-26 | 2010-09-30 | The Regents Of The University Of California | Mesenchymal stem cells producing inhibitory rna for disease modification |
| TWI576432B (zh) * | 2009-04-07 | 2017-04-01 | 陶氏農業科學公司 | 序列特異性核酸酶之奈米粒子媒介式遞送技術 |
| WO2011106376A2 (en) * | 2010-02-23 | 2011-09-01 | The General Hospital Corporation | Use of microvesicles in the treatment of medical conditions |
| CA2792035A1 (en) * | 2010-03-02 | 2011-09-09 | Vindico Nanobio Technology, Inc. | Compositions and methods for treating or preventing immuno-inflammatory disease |
| US20140363496A1 (en) | 2011-01-07 | 2014-12-11 | Vindico NanoBio Technology Inc. | Compositions and Methods for Inducing Nanoparticle-mediated Microvascular Embolization of Tumors |
| AU2012249390B2 (en) * | 2011-04-27 | 2017-03-30 | Amyris, Inc. | Methods for genomic modification |
| EP3031921B1 (en) | 2012-12-12 | 2025-03-12 | The Broad Institute, Inc. | Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications |
| CN113355357B (zh) | 2012-12-12 | 2024-12-03 | 布罗德研究所有限公司 | 对用于序列操纵的改进的系统、方法和酶组合物进行的工程化和优化 |
| RU2662932C2 (ru) * | 2013-03-14 | 2018-07-31 | Карибо Биосайенсиз, Инк. | Композиции и способы с участием нуклеиновых кислот, нацеленных на нуклеиновые кислоты |
| WO2014194190A1 (en) * | 2013-05-30 | 2014-12-04 | The Penn State Research Foundation | Gene targeting and genetic modification of plants via rna-guided genome editing |
| EP3155116A4 (en) | 2014-06-10 | 2017-12-27 | Massachusetts Institute Of Technology | Method for gene editing |
-
2016
- 2016-06-30 US US15/199,021 patent/US20170000743A1/en not_active Abandoned
- 2016-07-01 EP EP16818879.5A patent/EP3317414A4/en not_active Withdrawn
- 2016-07-01 CA CA2991109A patent/CA2991109A1/en active Pending
- 2016-07-01 AU AU2016288237A patent/AU2016288237B2/en not_active Ceased
- 2016-07-01 WO PCT/US2016/040673 patent/WO2017004509A1/en not_active Ceased
- 2016-07-01 JP JP2018520385A patent/JP6993966B2/ja active Active
- 2016-07-01 HK HK18114337.3A patent/HK1255209A1/zh unknown
- 2016-07-01 CN CN201680050998.3A patent/CN108699563A/zh active Pending
-
2019
- 2019-06-05 JP JP2019105213A patent/JP2019165745A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018532408A5 (https=) | ||
| Huang et al. | The landscape of mRNA nanomedicine | |
| AU2016288237B2 (en) | Compositions and methods for delivery of gene editing tools using polymeric vesicles | |
| EP3449004B1 (en) | Poly(histidine)-based micelles for complexation and delivery of proteins and nucleic acids | |
| Kaczmarek et al. | Advances in the delivery of RNA therapeutics: from concept to clinical reality | |
| Kauffman et al. | Materials for non-viral intracellular delivery of messenger RNA therapeutics | |
| Zhou et al. | Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors | |
| CN113710799B (zh) | 用于在LNP中使用的编码CAS9的优化mRNA | |
| Lin et al. | Targeting materials and strategies for RNA delivery | |
| Yin et al. | Non-viral vectors for gene-based therapy | |
| Rhym et al. | Nanoscale delivery platforms for RNA therapeutics: Challenges and the current state of the art | |
| JP2025529925A (ja) | 安定な脂質またはリピドイドナノ粒子懸濁液 | |
| Ma et al. | Bioinspired spatiotemporal management toward RNA therapies | |
| JP2026506360A (ja) | 核酸カーゴのデリバリーのためのナノ粒子 | |
| Porte et al. | A molecular view of lipid nanoparticles: insights into their morphology and structural plasticity | |
| Man et al. | Unlocking the potential of RNA-based therapeutics in the lung: current status and future directions | |
| Kola et al. | RNA-based vaccines and therapeutics against intracellular pathogens | |
| EP3238727B1 (en) | Non-aggregating immunostimulatory oligonucleotides | |
| US20250146021A1 (en) | Folding mrna into a nanoscale delivery vehicle | |
| Aldosari et al. | Lipid Nanoparticles as Delivery Systems for RNA-Based Vaccines. Pharmaceutics 2021, 13, 206 | |
| Gaul | Development of an integrated device-RNAi particle platform for the treatment of cystic fibrosis via inhalation | |
| EP4442257A1 (en) | Nanoparticle compositions comprising one or more variants of poly(d,l-lactic-co-glycolic acid) | |
| WO2025045767A1 (en) | Stabilized lipid and lipidoid nanoparticle formulations with specific surfactant properties for enhanced pharmaceutical applications | |
| WO2025213270A1 (en) | Method of delivering nucleic acid to t cells and compositions for use thereof | |
| Wu et al. | Unlocking the potential of RNA-based therapeutics in the lung: current status and future |