JP2018529760A5 - - Google Patents
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- Publication number
- JP2018529760A5 JP2018529760A5 JP2018527836A JP2018527836A JP2018529760A5 JP 2018529760 A5 JP2018529760 A5 JP 2018529760A5 JP 2018527836 A JP2018527836 A JP 2018527836A JP 2018527836 A JP2018527836 A JP 2018527836A JP 2018529760 A5 JP2018529760 A5 JP 2018529760A5
- Authority
- JP
- Japan
- Prior art keywords
- fviii
- coagulation factor
- modified
- protein
- hours
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562203973P | 2015-08-12 | 2015-08-12 | |
| US62/203,973 | 2015-08-12 | ||
| PCT/US2016/046264 WO2017027545A1 (en) | 2015-08-12 | 2016-08-10 | Methods and compositions related to long half-life coagulation complexes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018529760A JP2018529760A (ja) | 2018-10-11 |
| JP2018529760A5 true JP2018529760A5 (https=) | 2020-12-03 |
Family
ID=57983769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018527836A Revoked JP2018529760A (ja) | 2015-08-12 | 2016-08-10 | 長半減期凝固複合体と関連する方法及び組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10596232B2 (https=) |
| EP (1) | EP3334452A4 (https=) |
| JP (1) | JP2018529760A (https=) |
| KR (1) | KR20180031775A (https=) |
| CN (1) | CN107921103A (https=) |
| AU (1) | AU2016304842A1 (https=) |
| BR (1) | BR112018002838A2 (https=) |
| CA (1) | CA2994971A1 (https=) |
| IL (1) | IL257406A (https=) |
| WO (1) | WO2017027545A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020061281A1 (en) * | 2018-09-19 | 2020-03-26 | Cell Machines, Inc. | Methods and compositions related to improved factor viii long half-life coagulation complexes |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4002531A (en) | 1976-01-22 | 1977-01-11 | Pierce Chemical Company | Modifying enzymes with polyethylene glycol and product produced thereby |
| US5349052A (en) | 1988-10-20 | 1994-09-20 | Royal Free Hospital School Of Medicine | Process for fractionating polyethylene glycol (PEG)-protein adducts and an adduct for PEG and granulocyte-macrophage colony stimulating factor |
| EP0401384B1 (en) | 1988-12-22 | 1996-03-13 | Kirin-Amgen, Inc. | Chemically modified granulocyte colony stimulating factor |
| US5324844A (en) | 1989-04-19 | 1994-06-28 | Enzon, Inc. | Active carbonates of polyalkylene oxides for modification of polypeptides |
| GB9317618D0 (en) | 1993-08-24 | 1993-10-06 | Royal Free Hosp School Med | Polymer modifications |
| US5643575A (en) | 1993-10-27 | 1997-07-01 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
| DE69800640T2 (de) | 1997-01-29 | 2001-07-05 | Polymasc Pharmaceuticals Plc, London | Pegylationsverfahren |
| KR100512483B1 (ko) | 2003-05-07 | 2005-09-05 | 선바이오(주) | 신규한 폴리에틸렌글리콜-말레이미드 유도체의 합성방법 |
| US20110040073A1 (en) * | 2006-04-07 | 2011-02-17 | Novo Nordisk Healthcare A/G | Covalent Factor VII-Tissue Factor Complex |
| AU2007338298B2 (en) | 2006-12-22 | 2013-02-07 | Csl Behring Gmbh | Modified coagulation factors with prolonged in vivo half-life |
| KR20120061898A (ko) | 2009-08-20 | 2012-06-13 | 체에스엘 베링 게엠베하 | 출혈성 장애의 치료요법 및 예방 치료에 있어서의 비정맥내 투여를 위한 알부민 융합 응고 인자 |
| JP5826772B2 (ja) * | 2010-02-16 | 2015-12-02 | ノヴォ ノルディスク アー／エス | コンジュゲートタンパク質 |
| CN105153313A (zh) | 2010-02-16 | 2015-12-16 | 诺沃—诺迪斯克有限公司 | 因子viii融合蛋白 |
| HUE049352T2 (hu) * | 2010-12-22 | 2020-09-28 | Baxalta GmbH | Anyagok és módszerek egy vízoldható zsírsavszármazéknak egy fehérjéhez való konjugálására |
| DK2804623T3 (da) | 2012-01-12 | 2019-11-11 | Bioverativ Therapeutics Inc | Kimære faktor viii-polypeptider og anvendelser deraf |
| WO2013120939A1 (en) | 2012-02-15 | 2013-08-22 | Csl Behring Gmbh | Von willebrand factor variants having improved factor viii binding affinity |
| HRP20200007T1 (hr) | 2012-07-11 | 2020-03-20 | Bioverativ Therapeutics Inc. | Kompleks proteina faktora viii s xten i von willebrandovim faktorom, te njegova uporaba |
| EP2796145B1 (en) * | 2013-04-22 | 2017-11-01 | CSL Ltd. | A covalent complex of von willebrand factor and faktor viii linked by a disulphide bridge |
| FR3007860A1 (fr) * | 2013-06-27 | 2015-01-02 | France Telecom | Procede d'interaction entre un objet numerique, representatif d'au moins un objet reel ou virtuel localise dans un perimetre geographique distant, et un dispositif de pointage local |
| WO2014210547A1 (en) * | 2013-06-28 | 2014-12-31 | Biogen Idec Ma Inc. | Thrombin cleavable linker |
-
2016
- 2016-08-10 CN CN201680050833.6A patent/CN107921103A/zh active Pending
- 2016-08-10 BR BR112018002838A patent/BR112018002838A2/pt not_active Application Discontinuation
- 2016-08-10 AU AU2016304842A patent/AU2016304842A1/en not_active Abandoned
- 2016-08-10 EP EP16835805.9A patent/EP3334452A4/en not_active Withdrawn
- 2016-08-10 KR KR1020187005903A patent/KR20180031775A/ko not_active Withdrawn
- 2016-08-10 US US15/751,239 patent/US10596232B2/en not_active Expired - Fee Related
- 2016-08-10 CA CA2994971A patent/CA2994971A1/en not_active Abandoned
- 2016-08-10 JP JP2018527836A patent/JP2018529760A/ja not_active Revoked
- 2016-08-10 WO PCT/US2016/046264 patent/WO2017027545A1/en not_active Ceased
-
2018
- 2018-02-07 IL IL257406A patent/IL257406A/en unknown
-
2020
- 2020-02-26 US US16/801,480 patent/US20200289624A1/en not_active Abandoned
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