JP2018528191A5 - - Google Patents

Download PDF

Info

Publication number
JP2018528191A5
JP2018528191A5 JP2018508678A JP2018508678A JP2018528191A5 JP 2018528191 A5 JP2018528191 A5 JP 2018528191A5 JP 2018508678 A JP2018508678 A JP 2018508678A JP 2018508678 A JP2018508678 A JP 2018508678A JP 2018528191 A5 JP2018528191 A5 JP 2018528191A5
Authority
JP
Japan
Prior art keywords
protein
mixture
mage
peptogenic
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2018508678A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018528191A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2016/047620 external-priority patent/WO2017031353A1/en
Publication of JP2018528191A publication Critical patent/JP2018528191A/ja
Publication of JP2018528191A5 publication Critical patent/JP2018528191A5/ja
Priority to JP2022099482A priority Critical patent/JP2022123088A/ja
Priority to JP2025017152A priority patent/JP2025081372A/ja
Withdrawn legal-status Critical Current

Links

JP2018508678A 2015-08-19 2016-08-18 抗体を生成する新規な方法 Withdrawn JP2018528191A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022099482A JP2022123088A (ja) 2015-08-19 2022-06-21 抗体を生成する新規な方法
JP2025017152A JP2025081372A (ja) 2015-08-19 2025-02-04 抗体を生成する新規な方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562207022P 2015-08-19 2015-08-19
US62/207,022 2015-08-19
PCT/US2016/047620 WO2017031353A1 (en) 2015-08-19 2016-08-18 Novel methods of generating antibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022099482A Division JP2022123088A (ja) 2015-08-19 2022-06-21 抗体を生成する新規な方法

Publications (2)

Publication Number Publication Date
JP2018528191A JP2018528191A (ja) 2018-09-27
JP2018528191A5 true JP2018528191A5 (enExample) 2019-09-12

Family

ID=56802717

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018508678A Withdrawn JP2018528191A (ja) 2015-08-19 2016-08-18 抗体を生成する新規な方法
JP2022099482A Pending JP2022123088A (ja) 2015-08-19 2022-06-21 抗体を生成する新規な方法
JP2025017152A Pending JP2025081372A (ja) 2015-08-19 2025-02-04 抗体を生成する新規な方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2022099482A Pending JP2022123088A (ja) 2015-08-19 2022-06-21 抗体を生成する新規な方法
JP2025017152A Pending JP2025081372A (ja) 2015-08-19 2025-02-04 抗体を生成する新規な方法

Country Status (5)

Country Link
US (2) US11384138B2 (enExample)
EP (1) EP3337822A1 (enExample)
JP (3) JP2018528191A (enExample)
CA (1) CA2995838A1 (enExample)
WO (1) WO2017031353A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7048608B2 (ja) 2016-08-15 2022-04-05 チルドレンズ メディカル センター コーポレーション Apom-fc融合タンパク質、それとスフィンゴシン1-リン酸(s1p)との複合体、および血管疾患および非血管疾患を処置するための方法
AU2017366924A1 (en) 2016-12-01 2019-07-11 The Trustees Of Columbia University In The City Of New York Serological assay for Zika virus infection
CN111836646A (zh) * 2017-08-15 2020-10-27 儿童医学中心公司 Apom-fc融合蛋白及其用途
WO2019118918A1 (en) * 2017-12-15 2019-06-20 Aleta Biotherapeutics Inc. Cd19 variants
SG11202012653XA (en) 2018-06-19 2021-01-28 Biontech Us Inc Neoantigens and uses thereof
US12415847B2 (en) 2018-10-12 2025-09-16 Children's Medical Center Corporation ApoM-Fc fusion proteins for treating lung diseases
WO2020219896A1 (en) * 2019-04-26 2020-10-29 Beijing Xuanyi Pharmasciences Co., Ltd. Cd80 variant proteins and uses thereof
TW202116797A (zh) 2019-07-30 2021-05-01 大學健康網絡 Ii類mhc分子及其使用方法
TWI881991B (zh) * 2019-07-30 2025-05-01 大學健康網絡 Ii類mhc分子及其使用方法
CN110592032B (zh) * 2019-10-14 2021-04-13 北京理工大学 泛素连接酶Smurf1突变体、编码基因及用途
CN110760597B (zh) * 2019-11-22 2022-08-23 西北农林科技大学 一种检测黄牛ncstn基因拷贝数变异的方法及其应用
EP3845554A1 (en) * 2019-12-30 2021-07-07 Technische Universität Dortmund Method for determining 5-methylcytosine configurations in dna
EP4208197A1 (en) * 2020-09-04 2023-07-12 Rutgers, The State University of New Jersey Sars-cov-2 vaccines and antibodies
WO2022076947A1 (en) * 2020-10-09 2022-04-14 The General Hospital Corporation Peptide inhibitors of glioma-associated oncogene derived from the coiled-coil dimerization domain of kif7
EP4305190A4 (en) 2021-03-11 2025-03-26 Iggenix, Inc. METHODS AND SYSTEMS FOR PREDICTING AN ALLERGIC REACTION
CN117482090A (zh) * 2023-11-07 2024-02-02 中国人民解放军空军军医大学 一种化合物在调节tgr5受体活性及其在神经保护或抑郁症治疗中的应用

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4714681A (en) 1981-07-01 1987-12-22 The Board Of Reagents, The University Of Texas System Cancer Center Quadroma cells and trioma cells and methods for the production of same
US4474893A (en) 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
JPS6147500A (ja) 1984-08-15 1986-03-07 Res Dev Corp Of Japan キメラモノクロ−ナル抗体及びその製造法
EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
GB2183662B (en) 1985-04-01 1989-01-25 Celltech Ltd Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
DE3689123T2 (de) 1985-11-01 1994-03-03 Xoma Corp Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung.
GB8601597D0 (en) 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
US4925648A (en) 1988-07-29 1990-05-15 Immunomedics, Inc. Detection and treatment of infectious and inflammatory lesions
US5601819A (en) 1988-08-11 1997-02-11 The General Hospital Corporation Bispecific antibodies for selective immune regulation and for selective immune cell binding
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
EP0394827A1 (en) 1989-04-26 1990-10-31 F. Hoffmann-La Roche Ag Chimaeric CD4-immunoglobulin polypeptides
US5766883A (en) 1989-04-29 1998-06-16 Delta Biotechnology Limited Polypeptides
EP0739904A1 (en) 1989-06-29 1996-10-30 Medarex, Inc. Bispecific reagents for aids therapy
US5413923A (en) 1989-07-25 1995-05-09 Cell Genesys, Inc. Homologous recombination for universal donor cells and chimeric mammalian hosts
FR2650598B1 (fr) 1989-08-03 1994-06-03 Rhone Poulenc Sante Derives de l'albumine a fonction therapeutique
US5676954A (en) 1989-11-03 1997-10-14 Vanderbilt University Method of in vivo delivery of functioning foreign genes
EP1690935A3 (en) 1990-01-12 2008-07-30 Abgenix, Inc. Generation of xenogeneic antibodies
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5814318A (en) 1990-08-29 1998-09-29 Genpharm International Inc. Transgenic non-human animals for producing heterologous antibodies
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
ES2246502T3 (es) 1990-08-29 2006-02-16 Genpharm International, Inc. Animales no humanos transgenicos capaces de producir anticuerpos heterologos.
DK0553244T4 (da) 1990-10-05 2005-08-01 Celldex Therapeutics Inc Målrettet immunostimulering med bispecifikke reagenser
AU8727291A (en) 1990-10-29 1992-06-11 Cetus Oncology Corporation Bispecific antibodies, method of production, and uses thereof
EP0582595A1 (en) 1991-04-26 1994-02-16 Surface Active Limited Novel antibodies, and methods for their use
US5661133B1 (en) 1991-11-12 1999-06-01 Univ Michigan Collateral blood vessel formation in cardiac muscle by injecting a dna sequence encoding an angiogenic protein
PT1024191E (pt) 1991-12-02 2008-12-22 Medical Res Council Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
EP1306095A3 (en) 1992-03-05 2003-06-25 Board Of Regents, The University Of Texas System Methods and compositions for targeting the vasculature of solid tumors
ATE182651T1 (de) 1992-06-09 1999-08-15 Hoppe Ag Riegel und türschloss
US6030613A (en) 1995-01-17 2000-02-29 The Brigham And Women's Hospital, Inc. Receptor specific transepithelial transport of therapeutics
EP1658772A3 (en) 1995-01-17 2007-01-17 The Brigham And Women's Hospital, Inc. Receptor specific transepithelial transport of immunogens
CA2219361C (en) 1995-04-27 2012-02-28 Abgenix, Inc. Human antibodies derived from immunized xenomice
WO1996034096A1 (en) 1995-04-28 1996-10-31 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5916771A (en) 1996-10-11 1999-06-29 Abgenix, Inc. Production of a multimeric protein by cell fusion method
EP1972194A1 (en) 1996-12-03 2008-09-24 Amgen Fremont Inc. Transgenic mammals having human ig loci including plural vh and vk regions and antibodies produced therefrom
US7118874B2 (en) 1998-10-09 2006-10-10 Variation Biotechnologies Inc. Immunogenic formulation and process for preparation thereof
US6511832B1 (en) 1999-10-06 2003-01-28 Texas A&M University System In vitro synthesis of capped and polyadenylated mRNAs using baculovirus RNA polymerase
EP1278551A2 (en) 2000-04-21 2003-01-29 Vical Incorporated Compositions and methods for (in vivo) delivery of polynucleotide-based therapeutics
FR2868318B1 (fr) 2004-04-01 2012-11-16 Commissariat Energie Atomique Antigene tat stabilise et ses applications pour la vaccination anti-vih
US20080038280A1 (en) * 2004-10-14 2008-02-14 Government Of The United States Of America A32 Monoclonal Antibody Fusion Proteins For Use As Hiv Inhibitors And Vaccines
WO2008064488A1 (en) 2006-11-30 2008-06-05 Variation Biotechnologies Inc. Influenza vaccine formulation
US20110195089A1 (en) 2008-10-08 2011-08-11 The Adminstrators Of The Tulane Educational Fund Compositions, methods, and kits for enhancing the immunogenicity of pathogenic antigens
CN102060929A (zh) * 2010-06-07 2011-05-18 夏书奇 T细胞免疫平衡肽

Similar Documents

Publication Publication Date Title
JP2022123088A (ja) 抗体を生成する新規な方法
US20230330210A1 (en) Stabilized influenza hemagglutinin stem region trimers and uses thereof
JP2010533649A5 (enExample)
Ellebedy et al. Re-engaging cross-reactive memory B cells: the influenza puzzle
Rajendran et al. Analysis of anti-influenza virus neuraminidase antibodies in children, adults, and the elderly by ELISA and enzyme inhibition: evidence for original antigenic sin
JP7269166B2 (ja) 免疫抑制抵抗性が増したt細胞
Zhao et al. Advances in the study of HLA-restricted epitope vaccines
Fernandez-Tejada et al. Designing synthetic vaccines for HIV
JP2012500652A5 (enExample)
US12612461B2 (en) Single domain antibodies against CLL-1
Gupta et al. Receptor-ligand based molecular interaction to discover adjuvant for immune cell TLRs to develop next-generation vaccine
Sastry et al. Targeting hepatitis B virus-infected cells with a T-cell receptor-like antibody
US10906943B2 (en) Virus-like particles with high-density coating for inducing the expression of antibodies
Lin et al. Recombinant trimeric HA protein immunogenicity of H5N1 avian influenza viruses and their combined use with inactivated or adenovirus vaccines
JP2024029012A (ja) ペプチド交換蛋白質
US20170216425A1 (en) Avoiding narcolepsy risk in influenza vaccines
Shah et al. Challenges and considerations in multi-epitope vaccine design surrounding toll-like receptors
JP2016523237A (ja) タンパク質−細胞コンジュゲート、その調製法および使用
KR20210097833A (ko) 신규한 포유동물 발현 인간 면역결핍 바이러스 외피 단백질 항원
Simerska et al. Ovalbumin lipid core peptide vaccines and their CD4+ and CD8+ T cell responses
Adler-Moore et al. Monomeric M2e antigen in VesiVax® liposomes stimulates protection against type a strains of influenza comparable to liposomes with multimeric forms of M2e
Brouwer et al. Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses
JP7329529B2 (ja) ヘマグルチニンを含む広範に防御的なワクチン組成物を生成する方法
Mollica et al. Strategies for developing tuberculosis vaccines: emerging approaches
Goll et al. The antibody landscapes against Group 1 and 2 influenza virus hemagglutinin following AS03 and MF59 adjuvanted H5N1 vaccination