JP2018525703A5 - - Google Patents
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- JP2018525703A5 JP2018525703A5 JP2017561708A JP2017561708A JP2018525703A5 JP 2018525703 A5 JP2018525703 A5 JP 2018525703A5 JP 2017561708 A JP2017561708 A JP 2017561708A JP 2017561708 A JP2017561708 A JP 2017561708A JP 2018525703 A5 JP2018525703 A5 JP 2018525703A5
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- JP
- Japan
- Prior art keywords
- biomarker
- value
- values
- determining
- control
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000090 biomarker Substances 0.000 claims 59
- 238000000034 method Methods 0.000 claims 36
- 230000014509 gene expression Effects 0.000 claims 9
- 238000012545 processing Methods 0.000 claims 7
- 239000000523 sample Substances 0.000 claims 7
- 230000003321 amplification Effects 0.000 claims 4
- 238000003199 nucleic acid amplification method Methods 0.000 claims 4
- 238000012360 testing method Methods 0.000 claims 4
- 238000003556 assay Methods 0.000 claims 3
- 238000000684 flow cytometry Methods 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 238000011002 quantification Methods 0.000 claims 3
- 238000004422 calculation algorithm Methods 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- 238000003752 polymerase chain reaction Methods 0.000 claims 2
- 238000003127 radioimmunoassay Methods 0.000 claims 2
- 238000000123 temperature gradient gel electrophoresis Methods 0.000 claims 2
- 108700028369 Alleles Proteins 0.000 claims 1
- 102100025472 Carcinoembryonic antigen-related cell adhesion molecule 4 Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 102100022898 Galactoside-binding soluble lectin 13 Human genes 0.000 claims 1
- 108091027305 Heteroduplex Proteins 0.000 claims 1
- 101000914325 Homo sapiens Carcinoembryonic antigen-related cell adhesion molecule 4 Proteins 0.000 claims 1
- 101000620927 Homo sapiens Galactoside-binding soluble lectin 13 Proteins 0.000 claims 1
- 101000691480 Homo sapiens Placenta-specific gene 8 protein Proteins 0.000 claims 1
- 101001097889 Homo sapiens Platelet-activating factor acetylhydrolase Proteins 0.000 claims 1
- 108010009254 Lysosomal-Associated Membrane Protein 1 Proteins 0.000 claims 1
- 102100035133 Lysosome-associated membrane glycoprotein 1 Human genes 0.000 claims 1
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- 102100037518 Platelet-activating factor acetylhydrolase Human genes 0.000 claims 1
- 102000016611 Proteoglycans Human genes 0.000 claims 1
- 108010067787 Proteoglycans Proteins 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 238000004458 analytical method Methods 0.000 claims 1
- 238000000137 annealing Methods 0.000 claims 1
- 238000003491 array Methods 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 235000014633 carbohydrates Nutrition 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 238000003776 cleavage reaction Methods 0.000 claims 1
- 238000003935 denaturing gradient gel electrophoresis Methods 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 230000002255 enzymatic effect Effects 0.000 claims 1
- 230000001747 exhibiting effect Effects 0.000 claims 1
- 238000010195 expression analysis Methods 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 238000004817 gas chromatography Methods 0.000 claims 1
- 230000002068 genetic effect Effects 0.000 claims 1
- 238000003317 immunochromatography Methods 0.000 claims 1
- 238000003364 immunohistochemistry Methods 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 238000004811 liquid chromatography Methods 0.000 claims 1
- 238000004949 mass spectrometry Methods 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 239000002207 metabolite Substances 0.000 claims 1
- 238000010208 microarray analysis Methods 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 238000003062 neural network model Methods 0.000 claims 1
- 230000001575 pathological effect Effects 0.000 claims 1
- 102000054765 polymorphisms of proteins Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 238000007637 random forest analysis Methods 0.000 claims 1
- 235000002020 sage Nutrition 0.000 claims 1
- 230000007017 scission Effects 0.000 claims 1
- 238000012163 sequencing technique Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 238000012706 support-vector machine Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2015901982A AU2015901982A0 (en) | 2015-05-28 | Validating biomarker measurement | |
| AU2015901982 | 2015-05-28 | ||
| PCT/AU2016/050388 WO2016187655A1 (en) | 2015-05-28 | 2016-05-20 | Validating biomarker measurement |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018525703A JP2018525703A (ja) | 2018-09-06 |
| JP2018525703A5 true JP2018525703A5 (enExample) | 2019-06-27 |
Family
ID=57392259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017561708A Pending JP2018525703A (ja) | 2015-05-28 | 2016-05-20 | バイオマーカー測定の妥当性確認 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10719579B2 (enExample) |
| EP (1) | EP3304093B1 (enExample) |
| JP (1) | JP2018525703A (enExample) |
| CN (1) | CN108323184A (enExample) |
| AU (1) | AU2016267392B2 (enExample) |
| CA (1) | CA2986787A1 (enExample) |
| DK (1) | DK3304093T3 (enExample) |
| HK (1) | HK1249182A1 (enExample) |
| WO (1) | WO2016187655A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016267392B2 (en) * | 2015-05-28 | 2021-12-09 | Immunexpress Pty Ltd | Validating biomarker measurement |
| US20180357361A1 (en) * | 2017-06-13 | 2018-12-13 | Feliks Frenkel | Systems and methods for identifying responders and non-responders to immune checkpoint blockade therapy |
| ES2923478T3 (es) | 2017-08-04 | 2022-09-27 | Billiontoone Inc | Determinación y análisis de resultados de una secuenciación con moléculas asociadas a una diana en una cuantificación asociada con dianas biológicas |
| WO2019046814A1 (en) | 2017-09-01 | 2019-03-07 | Venn Biosciences Corporation | IDENTIFICATION AND USE OF GLYCOPEPTIDES AS BIOMARKERS FOR THE DIAGNOSIS AND MONITORING OF TREATMENT |
| WO2019183052A1 (en) * | 2018-03-19 | 2019-09-26 | Sri International | Methods and systems for biomarker analysis |
| CN109055535A (zh) * | 2018-09-14 | 2018-12-21 | 北京泱深生物信息技术有限公司 | 血液中的分子作为诊断脓毒症的标志物 |
| CN109374904A (zh) * | 2018-10-29 | 2019-02-22 | 浙江医院 | 一种蛋白质类脓毒症标志物及其在严重脓毒症早期预警的应用及其筛选方法 |
| CN114829882B (zh) * | 2019-11-05 | 2023-02-28 | 阿比尔技术公司 | 植物产品中感染的预测 |
| US11049590B1 (en) | 2020-02-12 | 2021-06-29 | Peptilogics, Inc. | Artificial intelligence engine architecture for generating candidate drugs |
| WO2021202620A1 (en) * | 2020-03-31 | 2021-10-07 | The Board Of Trustees Of The Leland Stanford Junior University | Metabolomics approach combined with machine learning to recognize a medical condition |
| CN113488107B (zh) * | 2021-07-07 | 2022-07-19 | 广州华银康医疗集团股份有限公司 | 筛选免疫组库测序生物标志物的方法、设备和存储介质 |
| EP4195212A1 (en) * | 2021-12-08 | 2023-06-14 | A3P Biomedical AB (publ) | Certainty-based medical conclusion model adaptation |
| CN114628024A (zh) * | 2022-02-24 | 2022-06-14 | 重庆市急救医疗中心(重庆市第四人民医院、重庆市急救医学研究所) | 一种生物标志物组在制备用于辅助筛查脓毒症的产品中的用途和辅助筛查方法及其系统 |
| WO2025094604A1 (ja) * | 2023-10-31 | 2025-05-08 | アークレイ株式会社 | 検知方法、検知装置、検知システム、検知プログラム、及び記録媒体 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030148339A1 (en) | 2001-05-07 | 2003-08-07 | Hrissi Samartzidou | Artificial genes for use as controls in gene expression analysis systems |
| US7622260B2 (en) * | 2001-09-05 | 2009-11-24 | The Brigham And Women's Hospital, Inc. | Diagnostic and prognostic tests |
| US20040180365A1 (en) * | 2002-12-13 | 2004-09-16 | Affymetrix, Inc. | Methods and computer software products for gene expression data quality analysis |
| EP1789786A4 (en) * | 2004-08-18 | 2008-02-13 | Abbott Molecular Inc | DETERMINING DATA QUALITY AND / OR SEGMENTAL ANEUMS USING A COMPUTER SYSTEM |
| BRPI0609302A2 (pt) * | 2005-04-15 | 2011-10-11 | Becton Dickinson Co | métodos para prever o desenvolvimento de sepse e para diagnosticar sepse em um indivìduo a ser testado, microarranjo, kit para prever o desenvolvimento de sepse em um indivìduo a ser testado, produto de programa de computador, computador, sistema de computador para determinar se um indivìduo é susceptìvel de desenvolver sepse, sinal digital embutido em uma onda portadora, e, interface gráfica de usuário para determinar se um indivìduo é susceptìvel de desenvolver sepse |
| DE102005050933A1 (de) * | 2005-10-21 | 2007-04-26 | Justus-Liebig-Universität Giessen | Erfindung betreffend Expressionsprofile zur Vorhersage von septischen Zuständen |
| US20070255113A1 (en) * | 2006-05-01 | 2007-11-01 | Grimes F R | Methods and apparatus for identifying disease status using biomarkers |
| US20080213768A1 (en) * | 2006-08-17 | 2008-09-04 | Zhauhui Cai | Identification and use of biomarkers for non-invasive and early detection of liver injury |
| DE102007010252B4 (de) | 2007-03-02 | 2013-07-04 | Sirs-Lab Gmbh | Kontrollgene zur Normalisierung von Genexpressionsanalysedaten |
| CA2604317C (en) * | 2007-08-06 | 2017-02-28 | Historx, Inc. | Methods and system for validating sample images for quantitative immunoassays |
| JP4666237B2 (ja) * | 2008-07-09 | 2011-04-06 | ソニー株式会社 | 遺伝子検定方法、遺伝子検定プログラム及び遺伝子検定装置 |
| JP2013509588A (ja) * | 2009-10-29 | 2013-03-14 | テシス バイオサイエンス， インコーポレイテッド | ２型糖尿病の予防に対して一貫した改善をもたらすタンパク質バイオマーカーおよび脂質代謝物バイオマーカー |
| US20120035860A1 (en) * | 2010-04-29 | 2012-02-09 | Akmaev Viatcheslav R | GC Wave Correction for Array-Based Comparative Genomic Hybridization |
| EP2643483A4 (en) * | 2010-11-26 | 2014-04-30 | Immunexpress Pty Ltd | DIAGNOSTIC AND / OR SCREENING APPROPRIATIONS AND USES THEREFOR |
| CA2827894A1 (en) * | 2011-02-22 | 2012-08-30 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Circulating biomarkers |
| JP6211511B2 (ja) * | 2011-04-18 | 2017-10-11 | ディアミール, エルエルシーDiamir, Llc | ｍｉＲＮＡに基づくユニバーサルスクリーニングテスト（ＵＳＴ） |
| WO2013152989A2 (en) * | 2012-04-10 | 2013-10-17 | Eth Zurich | Biomarker assay and uses thereof for diagnosis, therapy selection, and prognosis of cancer |
| EP2836844B1 (en) * | 2012-04-13 | 2017-08-16 | Oasis Diagnostics Corporation | Specific salivary biomarkers for risk detection, early diagnosis, prognosis and monitoring of alzheimer's and parkinson's diseases |
| WO2014201516A2 (en) | 2013-06-20 | 2014-12-24 | Immunexpress Pty Ltd | Biomarker identification |
| EP3103046B1 (en) | 2014-02-06 | 2020-03-25 | Immunexpress Pty Ltd | Biomarker signature method, and apparatus and kits therefor |
| AU2016267392B2 (en) * | 2015-05-28 | 2021-12-09 | Immunexpress Pty Ltd | Validating biomarker measurement |
-
2016
- 2016-05-20 AU AU2016267392A patent/AU2016267392B2/en active Active
- 2016-05-20 DK DK16798945.8T patent/DK3304093T3/da active
- 2016-05-20 US US15/160,749 patent/US10719579B2/en active Active
- 2016-05-20 JP JP2017561708A patent/JP2018525703A/ja active Pending
- 2016-05-20 EP EP16798945.8A patent/EP3304093B1/en active Active
- 2016-05-20 US US15/577,733 patent/US20180107783A1/en active Pending
- 2016-05-20 WO PCT/AU2016/050388 patent/WO2016187655A1/en not_active Ceased
- 2016-05-20 CA CA2986787A patent/CA2986787A1/en not_active Abandoned
- 2016-05-20 HK HK18108825.4A patent/HK1249182A1/zh unknown
- 2016-05-20 CN CN201680043261.9A patent/CN108323184A/zh active Pending
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