JP2018522037A5 - - Google Patents
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- Publication number
- JP2018522037A5 JP2018522037A5 JP2018505431A JP2018505431A JP2018522037A5 JP 2018522037 A5 JP2018522037 A5 JP 2018522037A5 JP 2018505431 A JP2018505431 A JP 2018505431A JP 2018505431 A JP2018505431 A JP 2018505431A JP 2018522037 A5 JP2018522037 A5 JP 2018522037A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- phenyl
- trione
- pyrimidine
- pyrazino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *C(CC(N1c(c(F)c2)c(*)cc2C#Cc2ccccc2)=O)(C(N(CC2)I*)=O)N2C1=O Chemical compound *C(CC(N1c(c(F)c2)c(*)cc2C#Cc2ccccc2)=O)(C(N(CC2)I*)=O)N2C1=O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15179550.7 | 2015-08-03 | ||
| EP15179550 | 2015-08-03 | ||
| PCT/EP2016/068359 WO2017021384A1 (en) | 2015-08-03 | 2016-08-02 | Ethynyl derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018522037A JP2018522037A (ja) | 2018-08-09 |
| JP2018522037A5 true JP2018522037A5 (https=) | 2019-09-05 |
| JP6975511B2 JP6975511B2 (ja) | 2021-12-01 |
Family
ID=53776452
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018505431A Expired - Fee Related JP6975511B2 (ja) | 2015-08-03 | 2016-08-02 | エチニル誘導体 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US10011607B2 (https=) |
| EP (1) | EP3331882B1 (https=) |
| JP (1) | JP6975511B2 (https=) |
| KR (1) | KR20180030857A (https=) |
| CN (1) | CN107667107B (https=) |
| AR (1) | AR105556A1 (https=) |
| AU (1) | AU2016302696B2 (https=) |
| BR (1) | BR112017023951A2 (https=) |
| CA (1) | CA2983908A1 (https=) |
| CL (1) | CL2018000278A1 (https=) |
| CO (1) | CO2017011010A2 (https=) |
| IL (1) | IL255103B (https=) |
| MX (1) | MX2018001486A (https=) |
| PE (1) | PE20180357A1 (https=) |
| PH (1) | PH12018500247A1 (https=) |
| RU (1) | RU2722014C9 (https=) |
| TW (1) | TWI621619B (https=) |
| UA (1) | UA120888C2 (https=) |
| WO (1) | WO2017021384A1 (https=) |
| ZA (1) | ZA201707015B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102229608B1 (ko) | 2015-08-03 | 2021-03-19 | 아이크노스 사이언스 에스. 아. | Ror 감마 조절제로서의 신규한 화합물 |
| EA033686B1 (ru) | 2015-08-03 | 2019-11-15 | Bristol Myers Squibb Co | Гетероциклические соединения, применимые в качестве модуляторов tnf-альфа |
| GB201513742D0 (en) | 2015-08-03 | 2015-09-16 | Heptares Therapeutics Ltd | Muscarinic agonists |
| AR117469A1 (es) | 2018-12-21 | 2021-08-11 | Merck Patent Gmbh | Derivados de alquino disustituidos |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20120115252A (ko) * | 2009-11-06 | 2012-10-17 | 벤더르빌트 유니버시티 | Ｍｇｌｕｒ4 알로스테릭 강화제로서 아릴 및 헤테로아릴 설폰, 조성물 및 신경 기능이상을 치료하는 방법 |
| US8420661B2 (en) * | 2010-04-13 | 2013-04-16 | Hoffmann-La Roche Inc. | Arylethynyl derivatives |
| EP2702050B1 (en) * | 2011-04-26 | 2016-05-18 | F.Hoffmann-La Roche Ag | Pyrazolidin-3-one derivatives |
| EA029352B1 (ru) * | 2013-09-25 | 2018-03-30 | Ф. Хоффманн-Ля Рош Аг | Производные этинила |
| TWI649310B (zh) * | 2014-01-10 | 2019-02-01 | 赫孚孟拉羅股份公司 | 乙炔基衍生物 |
| HUE041392T2 (hu) * | 2014-02-25 | 2019-05-28 | Hoffmann La Roche | Etinil származékok |
-
2016
- 2016-08-01 AR ARP160102335A patent/AR105556A1/es unknown
- 2016-08-02 AU AU2016302696A patent/AU2016302696B2/en not_active Ceased
- 2016-08-02 PE PE2017002405A patent/PE20180357A1/es unknown
- 2016-08-02 MX MX2018001486A patent/MX2018001486A/es active IP Right Grant
- 2016-08-02 WO PCT/EP2016/068359 patent/WO2017021384A1/en not_active Ceased
- 2016-08-02 EP EP16745473.5A patent/EP3331882B1/en active Active
- 2016-08-02 CA CA2983908A patent/CA2983908A1/en not_active Abandoned
- 2016-08-02 UA UAA201801410A patent/UA120888C2/uk unknown
- 2016-08-02 CN CN201680029481.6A patent/CN107667107B/zh not_active Expired - Fee Related
- 2016-08-02 TW TW105124484A patent/TWI621619B/zh not_active IP Right Cessation
- 2016-08-02 RU RU2018105872A patent/RU2722014C9/ru active
- 2016-08-02 KR KR1020187003005A patent/KR20180030857A/ko not_active Ceased
- 2016-08-02 JP JP2018505431A patent/JP6975511B2/ja not_active Expired - Fee Related
- 2016-08-02 BR BR112017023951-5A patent/BR112017023951A2/pt not_active Application Discontinuation
-
2017
- 2017-10-17 ZA ZA2017/07015A patent/ZA201707015B/en unknown
- 2017-10-18 IL IL255103A patent/IL255103B/en active IP Right Grant
- 2017-10-27 CO CONC2017/0011010A patent/CO2017011010A2/es unknown
-
2018
- 2018-01-10 US US15/867,097 patent/US10011607B2/en active Active
- 2018-01-31 CL CL2018000278A patent/CL2018000278A1/es unknown
- 2018-02-01 PH PH12018500247A patent/PH12018500247A1/en unknown
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