JP2018519356A5 - - Google Patents
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- JP2018519356A5 JP2018519356A5 JP2018506815A JP2018506815A JP2018519356A5 JP 2018519356 A5 JP2018519356 A5 JP 2018519356A5 JP 2018506815 A JP2018506815 A JP 2018506815A JP 2018506815 A JP2018506815 A JP 2018506815A JP 2018519356 A5 JP2018519356 A5 JP 2018519356A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- domain
- car
- genetically modified
- kma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022209702A JP2023024793A (ja) | 2015-04-23 | 2022-12-27 | カッパ骨髄腫抗原キメラ抗原受容体およびその使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562151968P | 2015-04-23 | 2015-04-23 | |
| US62/151,968 | 2015-04-23 | ||
| US201562158407P | 2015-05-07 | 2015-05-07 | |
| US62/158,407 | 2015-05-07 | ||
| PCT/US2016/029203 WO2016172703A2 (en) | 2015-04-23 | 2016-04-25 | Kappa myeloma antigen chimeric antigen receptors and uses thereof |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021020594A Division JP2021073312A (ja) | 2015-04-23 | 2021-02-12 | カッパ骨髄腫抗原キメラ抗原受容体およびその使用 |
| JP2022209702A Division JP2023024793A (ja) | 2015-04-23 | 2022-12-27 | カッパ骨髄腫抗原キメラ抗原受容体およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018519356A JP2018519356A (ja) | 2018-07-19 |
| JP2018519356A5 true JP2018519356A5 (https=) | 2019-06-06 |
| JP7229768B2 JP7229768B2 (ja) | 2023-02-28 |
Family
ID=57143653
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018506815A Active JP7229768B2 (ja) | 2015-04-23 | 2016-04-25 | カッパ骨髄腫抗原キメラ抗原受容体およびその使用 |
| JP2021020594A Pending JP2021073312A (ja) | 2015-04-23 | 2021-02-12 | カッパ骨髄腫抗原キメラ抗原受容体およびその使用 |
| JP2022209702A Withdrawn JP2023024793A (ja) | 2015-04-23 | 2022-12-27 | カッパ骨髄腫抗原キメラ抗原受容体およびその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021020594A Pending JP2021073312A (ja) | 2015-04-23 | 2021-02-12 | カッパ骨髄腫抗原キメラ抗原受容体およびその使用 |
| JP2022209702A Withdrawn JP2023024793A (ja) | 2015-04-23 | 2022-12-27 | カッパ骨髄腫抗原キメラ抗原受容体およびその使用 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US11305011B2 (https=) |
| EP (2) | EP3286223B8 (https=) |
| JP (3) | JP7229768B2 (https=) |
| KR (1) | KR102623427B1 (https=) |
| CN (1) | CN107922489B (https=) |
| AU (1) | AU2016253126B2 (https=) |
| BR (1) | BR112017022838A2 (https=) |
| CA (1) | CA2978964A1 (https=) |
| DK (1) | DK3286223T5 (https=) |
| ES (1) | ES2976236T3 (https=) |
| FI (1) | FI3286223T3 (https=) |
| HK (1) | HK1252854A1 (https=) |
| HR (1) | HRP20240415T1 (https=) |
| HU (1) | HUE065799T2 (https=) |
| IL (1) | IL255207B2 (https=) |
| PT (1) | PT3286223T (https=) |
| RU (1) | RU2743188C2 (https=) |
| WO (1) | WO2016172703A2 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3286223B8 (en) | 2015-04-23 | 2024-04-03 | HaemaLogiX Ltd | Kappa myeloma antigen chimeric antigen receptors and uses thereof |
| CN107529550A (zh) * | 2017-08-28 | 2018-01-02 | 马晓冬 | 一种基于PiggyBac载体的CD‑19‑CAR‑T系统构建方法 |
| CN109468278A (zh) * | 2017-09-08 | 2019-03-15 | 科济生物医药（上海）有限公司 | 基因工程化的t细胞及应用 |
| WO2019108932A1 (en) * | 2017-11-30 | 2019-06-06 | Haemalogix Pty. Ltd. | Methods for expanding kappa myeloma antigen chimeric antigen receptors expressing cells |
| SG11202009626QA (en) * | 2018-04-20 | 2020-10-29 | Medizinische Hochschule Hannover | Chimeric antigen receptor and car-t cells that bind a herpes virus antigen |
| WO2020004337A1 (ja) * | 2018-06-27 | 2020-01-02 | 国立大学法人名古屋大学 | Ｃｄ３７特異的キメラ抗原レセプター |
| US20220177573A1 (en) | 2018-07-09 | 2022-06-09 | Oslo Universitetssykehus Hf | Two chimeric antigen receptors specifically binding cd19 and igkappa |
| CN110832071A (zh) * | 2018-09-14 | 2020-02-21 | 上海原能细胞医学技术有限公司 | 表面包含免疫调节剂的细胞及其用途 |
| KR20210142088A (ko) * | 2018-12-03 | 2021-11-24 | 해마로직스 피티와이. 리미티드 | 치료방법 |
| WO2020181221A1 (en) * | 2019-03-07 | 2020-09-10 | Children's Medical Center Corporation | Targeted delivery of immune-modulating vhh and vhh-fusion protein |
| EP3976658A4 (en) * | 2019-05-24 | 2023-06-07 | Forty Seven, Inc. | Regimes for co-administration of immunotherapeutic agents against c-kit and cd47 |
| CN110305906B (zh) * | 2019-07-18 | 2021-11-12 | 山东大学第二医院 | 一种靶向pdl1的car嵌合受体的慢病毒载体及pdl1-car-t细胞 |
| CA3160759A1 (en) * | 2019-12-05 | 2021-06-10 | Vycellix, Inc. | Modulators of the immune escape mechanism for universal cell therapy |
| EP4126900A4 (en) * | 2020-03-27 | 2024-05-29 | Haemalogix Ltd | Composition and method |
| CN115698268A (zh) | 2020-05-04 | 2023-02-03 | 萨利欧基因治疗公司 | 基于转座的疗法 |
| WO2021232200A1 (en) * | 2020-05-18 | 2021-11-25 | Guangdong Tcrcure Biopharma Technology Co., Ltd. | Il-12 armored immune cell therapy and uses thereof |
| AR124414A1 (es) | 2020-12-18 | 2023-03-22 | Century Therapeutics Inc | Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable |
| WO2022268196A1 (zh) * | 2021-06-25 | 2022-12-29 | 天辰生物医药(苏州)有限公司 | 靶向gpc3的抗原结合蛋白 |
| WO2023010118A1 (en) * | 2021-07-29 | 2023-02-02 | Vor Biopharma Inc. | Nfat-responsive reporter systems for assessing chimeric antigen receptor activation and methods of making and using the same |
| KR102789265B1 (ko) * | 2022-04-14 | 2025-04-02 | 주식회사 셀랩메드 | 키메릭 항원 수용체 및 hgf 결합 억제 물질의 조합 요법 |
| KR20260013442A (ko) * | 2023-03-17 | 2026-01-28 | 카티전 테라퓨틱스, 인코포레이티드 | 키메라 항원 수용체의 장기 발현을 위해 조정된 세포내 신호전달 및 공동자극 도메인 |
| WO2025136986A2 (en) | 2023-12-18 | 2025-06-26 | Genzyme Corporation | Il-12 loss of potency muteins |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPR617901A0 (en) * | 2001-07-06 | 2001-08-02 | Pacmab Pty Ltd | Method for treating multiple myeloma |
| WO2004050836A2 (en) * | 2002-11-27 | 2004-06-17 | Biogen Idec Ma Inc. | Humanized antibodies against monocyte chemotactic proteins |
| JP2009503116A (ja) * | 2005-08-04 | 2009-01-29 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ベータ細胞疾患の治療および検出方法 |
| WO2010115238A1 (en) * | 2009-04-07 | 2010-10-14 | Immune System Therapeutics Ltd | Method for treating immune disorders |
| US20100330046A1 (en) * | 2009-05-21 | 2010-12-30 | Stratatech Corporation | Human skin substitutes expressing il-12 |
| ES2754394T3 (es) * | 2010-09-08 | 2020-04-17 | Chemotherapeutisches Forschungsinstitut Georg Speyer Haus | Receptores de antígenos quiméricos con una región bisagra optimizada |
| WO2013070468A1 (en) * | 2011-11-08 | 2013-05-16 | The Trustees Of The University Of Pennsylvania | Glypican-3-specific antibody and uses thereof |
| CA2896076C (en) * | 2012-12-21 | 2022-12-06 | Aveo Pharmaceuticals, Inc. | Anti-gdf15 antibodies |
| AU2014268364A1 (en) | 2013-05-24 | 2015-12-10 | Board Of Regents, The University Of Texas System | Chimeric antigen receptor-targeting monoclonal antibodies |
| CN104177499B (zh) * | 2013-05-27 | 2019-01-08 | 上海雅科生物科技有限公司 | 一种嵌合抗原受体、编码基因、表达载体及其应用 |
| US10208125B2 (en) * | 2013-07-15 | 2019-02-19 | University of Pittsburgh—of the Commonwealth System of Higher Education | Anti-mucin 1 binding agents and uses thereof |
| US20170049819A1 (en) | 2014-04-25 | 2017-02-23 | Bluebird Bio, Inc. | Kappa/lambda chimeric antigen receptors |
| EP3286223B8 (en) | 2015-04-23 | 2024-04-03 | HaemaLogiX Ltd | Kappa myeloma antigen chimeric antigen receptors and uses thereof |
-
2016
- 2016-04-25 EP EP16784085.9A patent/EP3286223B8/en active Active
- 2016-04-25 HK HK18112185.0A patent/HK1252854A1/zh unknown
- 2016-04-25 WO PCT/US2016/029203 patent/WO2016172703A2/en not_active Ceased
- 2016-04-25 IL IL255207A patent/IL255207B2/en unknown
- 2016-04-25 AU AU2016253126A patent/AU2016253126B2/en active Active
- 2016-04-25 RU RU2017138528A patent/RU2743188C2/ru active
- 2016-04-25 EP EP24151551.9A patent/EP4368641A3/en active Pending
- 2016-04-25 ES ES16784085T patent/ES2976236T3/es active Active
- 2016-04-25 HR HRP20240415TT patent/HRP20240415T1/hr unknown
- 2016-04-25 DK DK16784085.9T patent/DK3286223T5/da active
- 2016-04-25 US US15/568,271 patent/US11305011B2/en active Active
- 2016-04-25 KR KR1020177032005A patent/KR102623427B1/ko active Active
- 2016-04-25 CA CA2978964A patent/CA2978964A1/en active Pending
- 2016-04-25 JP JP2018506815A patent/JP7229768B2/ja active Active
- 2016-04-25 PT PT167840859T patent/PT3286223T/pt unknown
- 2016-04-25 FI FIEP16784085.9T patent/FI3286223T3/fi active
- 2016-04-25 CN CN201680031653.3A patent/CN107922489B/zh active Active
- 2016-04-25 HU HUE16784085A patent/HUE065799T2/hu unknown
- 2016-04-25 BR BR112017022838-6A patent/BR112017022838A2/en active IP Right Grant
-
2021
- 2021-02-12 JP JP2021020594A patent/JP2021073312A/ja active Pending
-
2022
- 2022-02-28 US US17/682,276 patent/US20220193232A1/en active Pending
- 2022-12-27 JP JP2022209702A patent/JP2023024793A/ja not_active Withdrawn
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