JP2018518179A - 直鎖状ポリα−１，３−グルカンを生成するためのグルコシルトランスフェラーゼアミノ酸配列モチーフ - Google Patents

直鎖状ポリα−１，３−グルカンを生成するためのグルコシルトランスフェラーゼアミノ酸配列モチーフ Download PDF

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JP2018518179A
JP2018518179A JP2017565150A JP2017565150A JP2018518179A JP 2018518179 A JP2018518179 A JP 2018518179A JP 2017565150 A JP2017565150 A JP 2017565150A JP 2017565150 A JP2017565150 A JP 2017565150A JP 2018518179 A JP2018518179 A JP 2018518179A
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seq
motif
amino acid
glucan
acid sequence
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JP2018518179A5 (OSRAM
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マーク・エス・ペイン
エフィム・ブラン
リチャード・アール・ボット
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EIDP Inc
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EI Du Pont de Nemours and Co
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/01—Hexosyltransferases (2.4.1)
    • C12Y204/01027—DNA beta-glucosyltransferase (2.4.1.27)

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  • Organic Chemistry (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2017565150A 2015-06-17 2016-06-15 直鎖状ポリα−１，３−グルカンを生成するためのグルコシルトランスフェラーゼアミノ酸配列モチーフ Pending JP2018518179A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562180788P 2015-06-17 2015-06-17
US201562180779P 2015-06-17 2015-06-17
US62/180,779 2015-06-17
US62/180,788 2015-06-17
PCT/US2016/037673 WO2016205401A1 (en) 2015-06-17 2016-06-15 Glucosyltransferase amino acid sequence motifs for producing linear poly alpha-1,3-glucan

Publications (2)

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JP2018518179A true JP2018518179A (ja) 2018-07-12
JP2018518179A5 JP2018518179A5 (OSRAM) 2019-07-11

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US (4) US9988610B2 (OSRAM)
EP (2) EP3310923A1 (OSRAM)
JP (1) JP2018518179A (OSRAM)
CN (1) CN107922958A (OSRAM)
AU (1) AU2016280700B2 (OSRAM)
CA (1) CA2989337A1 (OSRAM)
WO (2) WO2016205401A1 (OSRAM)

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AU2018221352B2 (en) 2017-02-16 2022-02-17 Nutrition & Biosciences USA 4, Inc. Crosslinked dextran and crosslinked dextran-poly alpha-1,3-glucan graft copolymers
AU2018272823B2 (en) 2017-05-23 2024-05-09 Nutrition & Biosciences USA 4, Inc. Enzymatic production of alpha-1,3-glucan
JP7384787B2 (ja) * 2017-09-13 2023-11-21 ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー，インコーポレイテッド 遺伝子操作されたグルコシルトランスフェラーゼ
EP3668970A1 (en) 2017-09-13 2020-06-24 DuPont Industrial Biosciences USA, LLC Engineered glucosyltransferases
JP7343490B2 (ja) 2017-10-13 2023-09-12 ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー，インコーポレイテッド 流動性バルク粒状多糖
WO2019094357A2 (en) 2017-11-10 2019-05-16 E. I. Du Pont De Nemours And Company Unique morphological polysaccharide
JP2021507955A (ja) 2017-12-14 2021-02-25 デュポン・インダストリアル・バイオサイエンシーズ・ユーエスエイ・エルエルシー α−１，３−グルカングラフトコポリマー
AU2019230061B2 (en) * 2018-03-09 2025-05-15 Nutrition & Biosciences USA 4, Inc. Engineered glucosyltransferases
US11859022B2 (en) 2018-10-25 2024-01-02 Nutrition & Biosciences USA 4, Inc. Alpha-1,3-glucan graft copolymers
US20220033531A1 (en) 2018-12-17 2022-02-03 Dupont Industrial Biosciences Usa,Llc Polysaccharide Derivatives and Compositions Comprising Same
CN115003805A (zh) * 2019-07-09 2022-09-02 营养与生物科学美国第四公司 工程化的α-1,3分支酶
CN115052489B (zh) 2019-08-16 2024-09-13 营养与生物科学美国第四公司 包含不溶性α-1,3-葡聚糖的基于面粉和粗粉的食品产品
US11608388B2 (en) 2019-11-06 2023-03-21 Nutrition & Biosciences USA 4, Inc. Highly crystalline alpha-1,3-glucan
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WO2021247810A1 (en) 2020-06-04 2021-12-09 Nutrition & Biosciences USA 4, Inc. Dextran-alpha-glucan graft copolymers and derivatives thereof
US12486338B2 (en) 2020-06-10 2025-12-02 Nutrition & Biosciences USA 4, Inc. Poly alpha-1,6-glucan derivatives and compositions comprising same
US20240150497A1 (en) 2021-02-19 2024-05-09 Nutrition & Biosciences USA 4, Inc. Polysaccharide derivatives for detergent compositions
CN117337308A (zh) 2021-05-04 2024-01-02 营养与生物科学美国4公司 包含氧化的不溶性α-葡聚糖的组合物
US20240294737A1 (en) 2021-05-04 2024-09-05 Nutrition & Biosciences USA 4, Inc. Compositions comprising insoluble alpha-glucan
CN117616054A (zh) 2021-07-13 2024-02-27 营养与生物科学美国4公司 阳离子葡聚糖酯衍生物
MX2024004006A (es) * 2021-09-30 2024-04-22 Int N&H Denmark Aps Metodo para reducir azucar en productos alimenticios.
US20250002695A1 (en) 2021-11-05 2025-01-02 Nutrition & Biosciences USA 4, Inc. Compositions comprising cationic alpha-1,6-glucan derivative and alpha-1,3-glucan
US20250032390A1 (en) 2021-12-16 2025-01-30 Nutrition & Biosciences USA 4, Inc. Compositions comprising cationic alpha-glucan ethers in aqueous polar organic solvents
EP4463519A1 (en) 2022-01-12 2024-11-20 Nutrition & Biosciences USA 4, Inc. Coating compositions comprising rubber and insoluble alpha-glucan
US20250188647A1 (en) 2022-03-21 2025-06-12 Nutrition & Biosciences USA 4, Inc. Compositions comprising insoluble alpha-glucan
JP2025523007A (ja) 2022-07-11 2025-07-17 ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー，インコーポレイテッド 両親媒性グルカンエステル誘導体
EP4601606A1 (en) 2022-10-14 2025-08-20 Nutrition & Biosciences USA 4, Inc. Compositions comprising water, cationic alpha-1,6-glucan ether and organic solvent
CN120076720A (zh) 2022-10-17 2025-05-30 国际N&H丹麦有限公司 用于改善基于植物的食料风味的方法
US20250339361A1 (en) 2022-11-02 2025-11-06 Nutrition & Biosciences USA 4, Inc. Compositions comprising xanthan gum and crystalline alpha-1,3-glucan
EP4622465A1 (en) 2022-11-23 2025-10-01 Nutrition & Biosciences USA 4, Inc. Hygienic treatment of surfaces with compositions comprising hydrophobically modified alpha-glucan derivative
EP4634242A1 (en) 2022-12-16 2025-10-22 Nutrition & Biosciences USA 4, Inc. Esterification of alpha-glucan comprising alpha-1,6 glycosidic linkages
AU2024242918A1 (en) 2023-03-29 2025-09-18 Danisco Us Inc. Methods for modifying texture in foodstuff via preferably in situ produced alpha-glucan
WO2024228945A1 (en) 2023-05-03 2024-11-07 Nutrition & Biosciences USA 4, Inc. Controlling bacterial cell adhesion with alpha-glucan comprising alpha-1,6 glycosidic linkages
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WO2014052386A2 (en) * 2012-09-25 2014-04-03 E. I. Du Pont De Nemours And Company Glucosyltransferase enzymes for production of glucan polymers
WO2015001034A1 (en) * 2013-07-05 2015-01-08 F. Hoffmann-La Roche Ag N-terminally truncated glycosyltransferases
JP2017510274A (ja) * 2014-03-25 2017-04-13 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ 代替のスクロース原料からのグルカンポリマーの生成

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JP2011501968A (ja) * 2007-10-31 2011-01-20 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー グリコロニトリルをグリコール酸に変換する場合のニトリラーゼ比活性を安定させるためのホルムアルデヒドの封鎖
WO2014052386A2 (en) * 2012-09-25 2014-04-03 E. I. Du Pont De Nemours And Company Glucosyltransferase enzymes for production of glucan polymers
WO2015001034A1 (en) * 2013-07-05 2015-01-08 F. Hoffmann-La Roche Ag N-terminally truncated glycosyltransferases
JP2017510274A (ja) * 2014-03-25 2017-04-13 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ 代替のスクロース原料からのグルカンポリマーの生成

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EP3310906A1 (en) 2018-04-25
US10508268B2 (en) 2019-12-17
EP3310923A1 (en) 2018-04-25
AU2016280700B2 (en) 2020-12-24
EP3310906B1 (en) 2020-05-06
WO2016205391A1 (en) 2016-12-22
US20170002335A1 (en) 2017-01-05
US20180305672A1 (en) 2018-10-25
CA2989337A1 (en) 2016-12-22
WO2016205401A1 (en) 2016-12-22
US20190112585A1 (en) 2019-04-18
AU2016280700A1 (en) 2018-01-04
US20170002336A1 (en) 2017-01-05
US9988610B2 (en) 2018-06-05
CN107922958A (zh) 2018-04-17
US10633638B2 (en) 2020-04-28

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