JP2018513715A - 異なる大きさの薬剤溶出性微小球ビーズによる肝動脈化学塞栓術後の薬剤濃度決定 - Google Patents
異なる大きさの薬剤溶出性微小球ビーズによる肝動脈化学塞栓術後の薬剤濃度決定 Download PDFInfo
- Publication number
- JP2018513715A JP2018513715A JP2017547143A JP2017547143A JP2018513715A JP 2018513715 A JP2018513715 A JP 2018513715A JP 2017547143 A JP2017547143 A JP 2017547143A JP 2017547143 A JP2017547143 A JP 2017547143A JP 2018513715 A JP2018513715 A JP 2018513715A
- Authority
- JP
- Japan
- Prior art keywords
- drug
- region
- interest
- contrast agent
- image data
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
- A61K49/0414—Particles, beads, capsules or spheres
- A61K49/0419—Microparticles, microbeads, microcapsules, microspheres, i.e. having a size or diameter higher or equal to 1 micrometer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/03—Computed tomography [CT]
- A61B6/032—Transmission computed tomography [CT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/42—Arrangements for detecting radiation specially adapted for radiation diagnosis
- A61B6/4208—Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
- A61B6/4241—Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector using energy resolving detectors, e.g. photon counting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/48—Diagnostic techniques
- A61B6/481—Diagnostic techniques involving the use of contrast agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/48—Diagnostic techniques
- A61B6/482—Diagnostic techniques involving multiple energy imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
- A61B6/504—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for diagnosis of blood vessels, e.g. by angiography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/40—Arrangements for generating radiation specially adapted for radiation diagnosis
- A61B6/405—Source units specially adapted to modify characteristics of the beam during the data acquisition process
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
- G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H30/00—ICT specially adapted for the handling or processing of medical images
- G16H30/20—ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Surgery (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- High Energy & Nuclear Physics (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Theoretical Computer Science (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Dentistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Surgical Instruments (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562134639P | 2015-03-18 | 2015-03-18 | |
| US62/134,639 | 2015-03-18 | ||
| EP15166519.7 | 2015-05-06 | ||
| EP15166519 | 2015-05-06 | ||
| PCT/EP2015/078737 WO2016146214A1 (en) | 2015-03-18 | 2015-12-04 | Drug concentration determination after transarterial chemoembolization with different sized drug-eluting microsphere beads |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018513715A true JP2018513715A (ja) | 2018-05-31 |
| JP2018513715A5 JP2018513715A5 (cg-RX-API-DMAC7.html) | 2019-01-17 |
Family
ID=53181069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017547143A Pending JP2018513715A (ja) | 2015-03-18 | 2015-12-04 | 異なる大きさの薬剤溶出性微小球ビーズによる肝動脈化学塞栓術後の薬剤濃度決定 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11172896B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3270785B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2018513715A (cg-RX-API-DMAC7.html) |
| CN (1) | CN107666861B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016146214A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3400877A1 (de) | 2017-05-10 | 2018-11-14 | Siemens Healthcare GmbH | Verfahren zur bildgebung eines untersuchungsbereichs mit erstem kontrastmittel und zweitem kontrastmittel |
| DE102019218589A1 (de) * | 2019-11-29 | 2021-06-02 | Bayer Aktiengesellschaft | Simultane Bilddarstellung von zwei unterschiedlichen funktionellen Bereichen |
| CN113546234B (zh) * | 2020-04-24 | 2022-09-20 | 苏州医本生命科技有限公司 | 一种血管介入具有示踪功能的药物制剂及其输送系统 |
| DE102021210860A1 (de) | 2021-09-28 | 2023-03-30 | Siemens Healthcare Gmbh | Computerimplementiertes Verfahren zur Auswertung von Bilddaten eines Patienten, Eingriffsanordnung, Computerprogramm und elektronisch lesbarer Datenträger |
| US12484865B2 (en) * | 2024-02-02 | 2025-12-02 | Varian Medical Systems, Inc. | Selective internal radiation therapy mapping via microbeads with different contrast materials |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080102029A1 (en) * | 2004-10-25 | 2008-05-01 | Celonova Biosciences, Inc. | Loadable Polymeric Particles For Enhanced Imaging In Clinical Applications And Methods Of Preparing And Using The Same |
| US20080113029A1 (en) * | 2004-10-25 | 2008-05-15 | Celonova Biosciences, Inc. | Color-Coded and Sized Loadable Polymeric Particles for Therapeutic and/or Diagnostic Applications and Methods of Preparing and Using the Same |
| JP2011528248A (ja) * | 2008-07-18 | 2011-11-17 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | スペクトルイメージング |
| JP2012506281A (ja) * | 2008-10-23 | 2012-03-15 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 分子イメージング |
| WO2013164725A1 (en) * | 2012-05-02 | 2013-11-07 | Koninklijke Philips N.V. | Spectral ct visualization of imageable drug eluting beads |
| WO2013186661A1 (en) * | 2012-06-14 | 2013-12-19 | Koninklijke Philips N.V. | Spectral imaging based decision support, treatment planning and/or intervention guidance |
| WO2014024061A1 (en) * | 2012-08-06 | 2014-02-13 | Koninklijke Philips N.V. | Dynamic contrast-enhanced imaging based permeability metric |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2360542T3 (es) * | 2004-10-25 | 2011-06-06 | Celonova Biosciences Germany Gmbh | Partículas poliméricas cargables para aplicaciones terapéuticas y/o diagnósticos y procedimientos para preparar y utilizar las mismas. |
| AU2007356895B2 (en) | 2007-07-25 | 2012-11-15 | Varian Medical Systems, Inc. | Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same |
| WO2011014562A1 (en) | 2009-07-28 | 2011-02-03 | North Carolina State University | Methods and devices for targeted injection of microspheres |
-
2015
- 2015-12-04 US US15/551,925 patent/US11172896B2/en active Active
- 2015-12-04 WO PCT/EP2015/078737 patent/WO2016146214A1/en not_active Ceased
- 2015-12-04 JP JP2017547143A patent/JP2018513715A/ja active Pending
- 2015-12-04 EP EP15805470.0A patent/EP3270785B1/en active Active
- 2015-12-04 CN CN201580077916.XA patent/CN107666861B/zh active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080102029A1 (en) * | 2004-10-25 | 2008-05-01 | Celonova Biosciences, Inc. | Loadable Polymeric Particles For Enhanced Imaging In Clinical Applications And Methods Of Preparing And Using The Same |
| US20080113029A1 (en) * | 2004-10-25 | 2008-05-15 | Celonova Biosciences, Inc. | Color-Coded and Sized Loadable Polymeric Particles for Therapeutic and/or Diagnostic Applications and Methods of Preparing and Using the Same |
| JP2011528248A (ja) * | 2008-07-18 | 2011-11-17 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | スペクトルイメージング |
| JP2012506281A (ja) * | 2008-10-23 | 2012-03-15 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 分子イメージング |
| WO2013164725A1 (en) * | 2012-05-02 | 2013-11-07 | Koninklijke Philips N.V. | Spectral ct visualization of imageable drug eluting beads |
| WO2013186661A1 (en) * | 2012-06-14 | 2013-12-19 | Koninklijke Philips N.V. | Spectral imaging based decision support, treatment planning and/or intervention guidance |
| WO2014024061A1 (en) * | 2012-08-06 | 2014-02-13 | Koninklijke Philips N.V. | Dynamic contrast-enhanced imaging based permeability metric |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3270785B1 (en) | 2020-07-08 |
| EP3270785A1 (en) | 2018-01-24 |
| CN107666861B (zh) | 2022-03-01 |
| WO2016146214A1 (en) | 2016-09-22 |
| US11172896B2 (en) | 2021-11-16 |
| US20180035960A1 (en) | 2018-02-08 |
| CN107666861A (zh) | 2018-02-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Hainfeld et al. | Micro-CT enables microlocalisation and quantification of Her2-targeted gold nanoparticles within tumour regions | |
| Seyal et al. | CT of the abdomen with reduced tube voltage in adults: a practical approach | |
| Damascelli et al. | A novel intraarterial chemotherapy using paclitaxel in albumin nanoparticles to treat advanced squamous cell carcinoma of the tongue: preliminary findings | |
| US6251059B1 (en) | Medical radiation treatment delivery apparatus | |
| CN107666861B (zh) | 在利用尺寸不同的药物洗脱微球珠粒进行经动脉化疗栓塞之后的药物浓度确定 | |
| US6162165A (en) | Medical radiation treatment device | |
| Weber et al. | Assessment of Diffusion-Weighted MRI and 18 F-Fluoro-Deoxyglucose PET/CT in Monitoring Early Response to Neoadjuvant Chemotherapy in Adenocarcinoma of the Esophagogastric Junction. | |
| Riederer et al. | Liquid embolic agents in spectral X-ray photon-counting computed tomography using tantalum K-edge imaging | |
| Wang et al. | Three-dimensional evaluation of lipiodol retention in HCC after chemoembolization: a quantitative comparison between CBCT and MDCT | |
| Xiong et al. | Current techniques for lymphatic imaging: State of the art and future perspectives | |
| Kurian et al. | The role of CT angiography in the evaluation of pediatric renovascular hypertension | |
| Tacher et al. | Multimodality imaging of ethiodized oil–loaded radiopaque microspheres during transarterial embolization of rabbits with VX2 liver tumors | |
| Carling et al. | Transarterial chemoembolization of liver metastases from uveal melanoma using irinotecan-loaded beads: treatment response and complications | |
| Yao et al. | Dual-phase cone-beam CT-based navigation imaging significantly enhances tumor detectability and aids superselective transarterial chemoembolization of liver cancer | |
| Kim et al. | Yttrium-90 radioembolization of the right inferior phrenic artery in 20 patients with hepatocellular carcinoma | |
| Schmitt et al. | Imaging artifacts of liquid embolic agents on conventional CT in an experimental in vitro model | |
| Gholamrezanezhad et al. | Evaluation of 70–150-μm doxorubicin-eluting beads for transcatheter arterial chemoembolization in the rabbit liver VX2 tumour model | |
| Peynircioğlu et al. | Quantitative liver tumor blood volume measurements by a C-arm CT post-processing software before and after hepatic arterial embolization therapy: comparison with MDCT perfusion | |
| Aliberti et al. | Chemoembolization adopting polyethylene glycol drug-eluting embolics loaded with doxorubicin for the treatment of hepatocellular carcinoma | |
| Rose et al. | The beauty and bane of pressure-directed embolotherapy: hemodynamic principles and preliminary clinical evidence | |
| EP2844147B1 (en) | Spectral ct visualization of imageable drug eluting beads | |
| Kennoki et al. | Transcatheter arterial chemoembolization with spherical embolic material for locally advanced breast cancer: first report of HepaSphere™ treatment for primary breast cancer | |
| Subramaniam | Science to Practice: Molecular Targeting with SPECT/CT and MR Imaging in Oncology—Integration of Functional and Structural Imaging | |
| Oprea-Lager et al. | [18F] fluoromethylcholine as a chemotherapy response read-out in prostate cancer cells | |
| Chung et al. | Transarterial chemoembolization as an alternative to radioembolization is associated with earlier tumor recurrence than in radioembolization-eligible patients |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20181130 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20181130 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20191119 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20191205 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20200228 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20200605 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20200811 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20201211 |
|
| C60 | Trial request (containing other claim documents, opposition documents) |
Free format text: JAPANESE INTERMEDIATE CODE: C60 Effective date: 20201211 |
|
| A911 | Transfer to examiner for re-examination before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20201222 |
|
| C21 | Notice of transfer of a case for reconsideration by examiners before appeal proceedings |
Free format text: JAPANESE INTERMEDIATE CODE: C21 Effective date: 20201224 |
|
| A912 | Re-examination (zenchi) completed and case transferred to appeal board |
Free format text: JAPANESE INTERMEDIATE CODE: A912 Effective date: 20210129 |
|
| C211 | Notice of termination of reconsideration by examiners before appeal proceedings |
Free format text: JAPANESE INTERMEDIATE CODE: C211 Effective date: 20210202 |
|
| C22 | Notice of designation (change) of administrative judge |
Free format text: JAPANESE INTERMEDIATE CODE: C22 Effective date: 20210304 |
|
| C23 | Notice of termination of proceedings |
Free format text: JAPANESE INTERMEDIATE CODE: C23 Effective date: 20210803 |
|
| C03 | Trial/appeal decision taken |
Free format text: JAPANESE INTERMEDIATE CODE: C03 Effective date: 20210831 |
|
| C30A | Notification sent |
Free format text: JAPANESE INTERMEDIATE CODE: C3012 Effective date: 20210831 |