JP2018513679A5 - - Google Patents
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- JP2018513679A5 JP2018513679A5 JP2017549623A JP2017549623A JP2018513679A5 JP 2018513679 A5 JP2018513679 A5 JP 2018513679A5 JP 2017549623 A JP2017549623 A JP 2017549623A JP 2017549623 A JP2017549623 A JP 2017549623A JP 2018513679 A5 JP2018513679 A5 JP 2018513679A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- cdna
- ctcs
- droplet
- ctc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562137891P | 2015-03-25 | 2015-03-25 | |
| US62/137,891 | 2015-03-25 | ||
| US201562219339P | 2015-09-16 | 2015-09-16 | |
| US62/219,339 | 2015-09-16 | ||
| US201562253619P | 2015-11-10 | 2015-11-10 | |
| US62/253,619 | 2015-11-10 | ||
| PCT/US2016/024367 WO2016154600A1 (en) | 2015-03-25 | 2016-03-25 | Digital analysis of circulating tumor cells in blood samples |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021012116A Division JP7203128B2 (ja) | 2015-03-25 | 2021-01-28 | 血液試料中の循環腫瘍細胞のデジタル分析 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018513679A JP2018513679A (ja) | 2018-05-31 |
| JP2018513679A5 true JP2018513679A5 (enExample) | 2019-05-09 |
| JP7144934B2 JP7144934B2 (ja) | 2022-09-30 |
Family
ID=56977798
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017549623A Active JP7144934B2 (ja) | 2015-03-25 | 2016-03-25 | 血液試料中の循環腫瘍細胞のデジタル分析 |
| JP2021012116A Active JP7203128B2 (ja) | 2015-03-25 | 2021-01-28 | 血液試料中の循環腫瘍細胞のデジタル分析 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021012116A Active JP7203128B2 (ja) | 2015-03-25 | 2021-01-28 | 血液試料中の循環腫瘍細胞のデジタル分析 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20180057889A1 (enExample) |
| EP (1) | EP3274476B1 (enExample) |
| JP (2) | JP7144934B2 (enExample) |
| KR (1) | KR102502087B1 (enExample) |
| CN (1) | CN107614698A (enExample) |
| AU (2) | AU2016238253B2 (enExample) |
| ES (1) | ES2954456T3 (enExample) |
| IL (1) | IL254639B (enExample) |
| WO (1) | WO2016154600A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107326085B (zh) | 2012-02-03 | 2022-05-03 | 加州理工学院 | 多路生化测定中信号的编码和解码 |
| EP3274476B1 (en) | 2015-03-25 | 2023-06-07 | The General Hospital Corporation | Digital analysis of circulating tumor cells in blood samples |
| US11371101B2 (en) | 2016-10-27 | 2022-06-28 | The General Hospital Corporation | Digital analysis of blood samples to determine efficacy of cancer therapies for specific cancers |
| US20180252722A1 (en) * | 2017-03-05 | 2018-09-06 | Yan Wang | PCR-based Method for Counting Circulating Tumor Cells |
| US11597963B2 (en) * | 2017-11-09 | 2023-03-07 | Biomillenia Sas | Microbial selection system |
| WO2019165242A1 (en) * | 2018-02-23 | 2019-08-29 | Paraskevi Giannakakou | Assay for detection of androgen receptor variants |
| CN108535145A (zh) * | 2018-03-09 | 2018-09-14 | 深圳市瑞图生物技术有限公司 | 快速检测外周血液中网织红细胞数量的方法及装置 |
| CN112424377A (zh) | 2018-04-17 | 2021-02-26 | 克罗玛科德公司 | 用于多重分析的方法和系统 |
| CN110456034B (zh) * | 2018-05-07 | 2022-07-22 | 上海市第十人民医院 | 一种循环肿瘤细胞的检测方法 |
| WO2020006404A1 (en) | 2018-06-29 | 2020-01-02 | The General Hospital Corporation | Isolating and analyzing rare brain-derived cells and particles |
| US12203129B2 (en) * | 2018-07-03 | 2025-01-21 | ChromaCode, Inc. | Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays |
| KR20210057765A (ko) * | 2018-09-11 | 2021-05-21 | 더 제너럴 하스피탈 코포레이션 | 간 질환을 검출하는 방법 |
| KR102380529B1 (ko) * | 2020-04-29 | 2022-03-31 | 인제대학교 산학협력단 | 전이성 전립선 암의 진단 및 예후 예측을 위한 혈중종양세포 기반 바이오 마커 조성물 |
| CN112662774A (zh) * | 2021-01-12 | 2021-04-16 | 南方医科大学南方医院 | 一种肝癌循环肿瘤细胞标志物及其应用 |
| CN117241878A (zh) | 2021-03-05 | 2023-12-15 | 伊努梅里斯公司 | 用于生成微滴和执行数字分析的系统和方法 |
| CN114395622A (zh) * | 2021-12-13 | 2022-04-26 | 深圳先进技术研究院 | 一种利用数字pcr检测循环肿瘤细胞egfr基因突变的方法及其应用 |
| DE102022211089A1 (de) * | 2022-10-19 | 2024-04-25 | Robert Bosch Gesellschaft mit beschränkter Haftung | Kombinierte Zellspezifische Markierung und Anreicherung von Biomarkern |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US889A (en) | 1838-08-20 | Mode of constructing metal bench-vises | ||
| US8535A (en) | 1851-11-18 | Stove-geate | ||
| DE29623597U1 (de) | 1996-11-08 | 1999-01-07 | Eppendorf - Netheler - Hinz Gmbh, 22339 Hamburg | Temperierblock mit Temperiereinrichtungen |
| US20080050393A1 (en) | 1998-12-03 | 2008-02-28 | Tang Y Tom | Novel nucleic acids and polypeptides |
| CA2311201A1 (en) * | 1999-08-05 | 2001-02-05 | Genset S.A. | Ests and encoded human proteins |
| WO2002012328A2 (en) * | 2000-08-03 | 2002-02-14 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| JP2004537261A (ja) | 2000-12-08 | 2004-12-16 | イプソゲン | 候補遺伝子のアレイを用いた原発性乳がんの遺伝子発現プロファイリング |
| JP2005512510A (ja) | 2001-05-16 | 2005-05-12 | ノバルティス アクチエンゲゼルシャフト | 予後および治療標的として乳癌で発現される遺伝子 |
| US20030073623A1 (en) | 2001-07-30 | 2003-04-17 | Drmanac Radoje T. | Novel nucleic acid sequences obtained from various cDNA libraries |
| US20040142325A1 (en) | 2001-09-14 | 2004-07-22 | Liat Mintz | Methods and systems for annotating biomolecular sequences |
| US20060275794A1 (en) | 2005-03-07 | 2006-12-07 | Invitrogen Corporation | Collections of matched biological reagents and methods for identifying matched reagents |
| US20070026417A1 (en) * | 2005-07-29 | 2007-02-01 | Martin Fuchs | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| WO2006121991A2 (en) | 2005-05-06 | 2006-11-16 | Diadexus, Inc. | Compositions and methods for detection, prognosis and treatment of breast cancer |
| EP2079838A1 (en) * | 2006-05-16 | 2009-07-22 | NuGEN Technologies, Inc. | Nucleic acid separation and purification method based on reversible charge interactions |
| EP2589668A1 (en) * | 2006-06-14 | 2013-05-08 | Verinata Health, Inc | Rare cell analysis using sample splitting and DNA tags |
| WO2009051734A1 (en) * | 2007-10-17 | 2009-04-23 | The General Hospital Corporation | Microchip-based devices for capturing circulating tumor cells and methods of their use |
| US9068181B2 (en) | 2008-05-23 | 2015-06-30 | The General Hospital Corporation | Microfluidic droplet encapsulation |
| US20120252015A1 (en) * | 2011-02-18 | 2012-10-04 | Bio-Rad Laboratories | Methods and compositions for detecting genetic material |
| US9625454B2 (en) * | 2009-09-04 | 2017-04-18 | The Research Foundation For The State University Of New York | Rapid and continuous analyte processing in droplet microfluidic devices |
| US20110166030A1 (en) * | 2009-09-30 | 2011-07-07 | Yixin Wang | Prediction of response to docetaxel therapy based on the presence of TMPRSSG2:ERG fusion in circulating tumor cells |
| JP5934657B2 (ja) | 2010-02-12 | 2016-06-15 | レインダンス テクノロジーズ， インコーポレイテッド | デジタル検体分析 |
| US20120329061A1 (en) * | 2010-03-11 | 2012-12-27 | Board Of Regents, The University Of Texas System | Quantitative rt-pcr detection for genes involved in epithelial mesenchymal transition in peripheral blood of cancer patients |
| AU2015268617A1 (en) | 2010-03-31 | 2016-01-07 | Sividon Diagnostics Gmbh | Method for breast cancer recurrence prediction under endocrine treatment |
| WO2011120984A1 (en) | 2010-03-31 | 2011-10-06 | Sividon Diagnostics Gmbh | Method for breast cancer recurrence prediction under endocrine treatment |
| US9650629B2 (en) * | 2010-07-07 | 2017-05-16 | Roche Molecular Systems, Inc. | Clonal pre-amplification in emulsion |
| WO2012024543A1 (en) | 2010-08-18 | 2012-02-23 | Caris Life Sciences Luxembourg Holdings | Circulating biomarkers for disease |
| WO2012115885A1 (en) | 2011-02-22 | 2012-08-30 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Circulating biomarkers |
| WO2012135397A2 (en) | 2011-03-29 | 2012-10-04 | Lisanti Michael P | Lactate-and ketones-induced gene signatures and use the same for diagnosing disease and predicting clinical outcome |
| US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
| GB2510539B (en) * | 2011-10-24 | 2016-04-20 | Gen Hospital Corp | Biomarkers of cancer |
| US9766244B2 (en) | 2012-07-02 | 2017-09-19 | The General Hospital Corporation | Diagnosis and monitoring treatment of prostate cancer |
| GB2539836B (en) * | 2012-08-13 | 2017-03-29 | Univ California | Methods for detecting target nucleic acids in sample lysate droplets |
| WO2014043628A1 (en) | 2012-09-14 | 2014-03-20 | Memorial Sloan-Kettering Cancer Center | Genes associated with dasatinib sensitivity |
| WO2014047285A1 (en) | 2012-09-19 | 2014-03-27 | Paraskevi Giannakakou | Identifying taxane sensitivity in prostate cancer patients |
| WO2014075067A1 (en) | 2012-11-12 | 2014-05-15 | Nanostring Technologies, Inc. | Methods to predict breast cancer outcome |
| WO2014165762A1 (en) | 2013-04-05 | 2014-10-09 | Raindance Technologies, Inc. | Rare cell analysis after negative selection |
| EP3033088A4 (en) | 2013-08-12 | 2017-03-08 | Tokai Pharmaceuticals, Inc. | Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies |
| US10202577B2 (en) | 2013-10-18 | 2019-02-12 | The General Hospital Corporation | Microfluidic sorting using high gradient magnetic fields |
| US9855270B2 (en) | 2014-03-13 | 2018-01-02 | Genentech, Inc. | Methods and compositions for modulating estrogen receptor mutants |
| RU2016148441A (ru) | 2014-05-21 | 2018-06-22 | Ф. Хоффманн-Ля Рош Аг | Способ лечения pr-положительного люминального а-типа рака молочной железы ингибитором pi3k пиктилисибом |
| JP6782698B2 (ja) | 2014-12-12 | 2020-11-11 | セルキュイティー インコーポレイテッド | がん患者を診断および処置するためのｅｒｂｂシグナル伝達経路活性の測定方法 |
| WO2016131924A1 (en) | 2015-02-20 | 2016-08-25 | Comelz S.P.A. | Method for cutting natural hides and the like |
| KR20170136525A (ko) | 2015-03-12 | 2017-12-11 | 얀센 파마슈티카 엔.브이. | 전립선암을 예측하기 위한 전혈 기반 mRNA 마커 및 그의 검출 방법 |
| EP3274476B1 (en) | 2015-03-25 | 2023-06-07 | The General Hospital Corporation | Digital analysis of circulating tumor cells in blood samples |
| US11371101B2 (en) | 2016-10-27 | 2022-06-28 | The General Hospital Corporation | Digital analysis of blood samples to determine efficacy of cancer therapies for specific cancers |
-
2016
- 2016-03-25 EP EP16769818.2A patent/EP3274476B1/en active Active
- 2016-03-25 WO PCT/US2016/024367 patent/WO2016154600A1/en not_active Ceased
- 2016-03-25 CN CN201680029396.XA patent/CN107614698A/zh active Pending
- 2016-03-25 JP JP2017549623A patent/JP7144934B2/ja active Active
- 2016-03-25 KR KR1020177030104A patent/KR102502087B1/ko active Active
- 2016-03-25 ES ES16769818T patent/ES2954456T3/es active Active
- 2016-03-25 AU AU2016238253A patent/AU2016238253B2/en active Active
- 2016-03-25 US US15/560,324 patent/US20180057889A1/en not_active Abandoned
-
2017
- 2017-09-24 IL IL254639A patent/IL254639B/en unknown
-
2020
- 2020-10-08 US US17/065,889 patent/US11898209B2/en active Active
-
2021
- 2021-01-28 JP JP2021012116A patent/JP7203128B2/ja active Active
-
2022
- 2022-09-15 AU AU2022231734A patent/AU2022231734A1/en not_active Abandoned
-
2023
- 2023-12-26 US US18/396,156 patent/US20240132969A1/en active Pending
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