JP2018512160A - 肺がんのタイピングのための方法 - Google Patents

肺がんのタイピングのための方法 Download PDF

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Publication number
JP2018512160A
JP2018512160A JP2017553970A JP2017553970A JP2018512160A JP 2018512160 A JP2018512160 A JP 2018512160A JP 2017553970 A JP2017553970 A JP 2017553970A JP 2017553970 A JP2017553970 A JP 2017553970A JP 2018512160 A JP2018512160 A JP 2018512160A
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Prior art keywords
biomarkers
classifier
classifier biomarkers
sample
hybridization
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JP2017553970A
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Japanese (ja)
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JP2018512160A5 (enExample
Inventor
ハワジン ファルキ，
ハワジン ファルキ，
マイラ ライ−ゴールドマン，
マイラ ライ−ゴールドマン，
グレッグ メイヒュー，
グレッグ メイヒュー，
チャールズ ペロウ，
チャールズ ペロウ，
デイビッド ニール ヘイズ，
デイビッド ニール ヘイズ，
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University of North Carolina at Chapel Hill
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University of North Carolina at Chapel Hill
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Application filed by University of North Carolina at Chapel Hill filed Critical University of North Carolina at Chapel Hill
Publication of JP2018512160A publication Critical patent/JP2018512160A/ja
Publication of JP2018512160A5 publication Critical patent/JP2018512160A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
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  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
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  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2017553970A 2015-04-14 2016-04-14 肺がんのタイピングのための方法 Pending JP2018512160A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562147547P 2015-04-14 2015-04-14
US62/147,547 2015-04-14
PCT/US2016/027503 WO2016168446A1 (en) 2015-04-14 2016-04-14 Methods for typing of lung cancer

Publications (2)

Publication Number Publication Date
JP2018512160A true JP2018512160A (ja) 2018-05-17
JP2018512160A5 JP2018512160A5 (enExample) 2019-05-23

Family

ID=57126370

Family Applications (1)

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JP2017553970A Pending JP2018512160A (ja) 2015-04-14 2016-04-14 肺がんのタイピングのための方法

Country Status (6)

Country Link
US (4) US20190203296A1 (enExample)
EP (1) EP3283654A4 (enExample)
JP (1) JP2018512160A (enExample)
CN (1) CN107849613A (enExample)
CA (1) CA2982775A1 (enExample)
WO (1) WO2016168446A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019516407A (ja) * 2016-05-17 2019-06-20 ジーンセントリック セラピューティクス， インコーポレイテッド 肺腺癌のサブタイピングのための方法
US12139765B2 (en) 2016-05-17 2024-11-12 Genecentric Therapeutics, Inc. Methods for subtyping of lung squamous cell carcinoma

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3149209B1 (en) * 2014-05-30 2021-02-17 Genecentric Therapeutics, Inc. Methods for typing of lung cancer
US11514289B1 (en) * 2016-03-09 2022-11-29 Freenome Holdings, Inc. Generating machine learning models using genetic data
CN109182526A (zh) * 2018-10-10 2019-01-11 杭州翱锐生物科技有限公司 用于早期肝癌辅助诊断的试剂盒及其检测方法
US20240336972A1 (en) * 2021-07-30 2024-10-10 Oregon Health & Science University Methods for selecting melanoma patients for therapy and methods of reducing or preventing melanoma metastasis
CN116403648B (zh) * 2023-06-06 2023-08-01 中国医学科学院肿瘤医院 一种基于多维分析建立的小细胞肺癌免疫新分型方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040009489A1 (en) * 2001-09-28 2004-01-15 Golub Todd R. Classification of lung carcinomas using gene expression analysis
WO2008151110A2 (en) * 2007-06-01 2008-12-11 The University Of North Carolina At Chapel Hill Molecular diagnosis and typing of lung cancer variants

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200413725A (en) * 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
US20060024692A1 (en) * 2002-09-30 2006-02-02 Oncotherapy Science, Inc. Method for diagnosing non-small cell lung cancers
CN101509035A (zh) * 2008-09-05 2009-08-19 中国人民解放军总医院 肺癌分型的基因序列及其应用
EP3149209B1 (en) * 2014-05-30 2021-02-17 Genecentric Therapeutics, Inc. Methods for typing of lung cancer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040009489A1 (en) * 2001-09-28 2004-01-15 Golub Todd R. Classification of lung carcinomas using gene expression analysis
WO2008151110A2 (en) * 2007-06-01 2008-12-11 The University Of North Carolina At Chapel Hill Molecular diagnosis and typing of lung cancer variants

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CLINICAL CANCER RESEARCH, vol. 14, no. 22, JPN6020004029, 2008, pages 7397 - 7404, ISSN: 0004364489 *
NATURE MEDICINE, vol. 14, no. 8, JPN6020004027, 2008, pages 1 - 14, ISSN: 0004364488 *
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 98, no. 24, JPN6020004026, 2001, pages 13790 - 13795, ISSN: 0004364487 *
THE JOURNAL OF MOLECULAR DIAGNOSTICS, vol. 15, no. 4, JPN6020004030, 2013, pages 485 - 497, ISSN: 0004206736 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019516407A (ja) * 2016-05-17 2019-06-20 ジーンセントリック セラピューティクス， インコーポレイテッド 肺腺癌のサブタイピングのための方法
JP7241353B2 (ja) 2016-05-17 2023-03-17 ジーンセントリック セラピューティクス， インコーポレイテッド 肺腺癌のサブタイピングのための方法
US12139765B2 (en) 2016-05-17 2024-11-12 Genecentric Therapeutics, Inc. Methods for subtyping of lung squamous cell carcinoma
US12139763B2 (en) 2016-05-17 2024-11-12 Genecentric Therapeutics, Inc. Methods for subtyping of lung adenocarcinoma

Also Published As

Publication number Publication date
US20220002820A1 (en) 2022-01-06
US20190203296A1 (en) 2019-07-04
EP3283654A4 (en) 2018-12-12
CA2982775A1 (en) 2016-10-20
WO2016168446A1 (en) 2016-10-20
US20220243283A1 (en) 2022-08-04
CN107849613A (zh) 2018-03-27
US20210147948A1 (en) 2021-05-20
EP3283654A1 (en) 2018-02-21

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