JP2018511555A5 - - Google Patents
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- Publication number
- JP2018511555A5 JP2018511555A5 JP2017538667A JP2017538667A JP2018511555A5 JP 2018511555 A5 JP2018511555 A5 JP 2018511555A5 JP 2017538667 A JP2017538667 A JP 2017538667A JP 2017538667 A JP2017538667 A JP 2017538667A JP 2018511555 A5 JP2018511555 A5 JP 2018511555A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- modified oligonucleotide
- wing segment
- composition according
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 C*OC1C2(CO*)OC(*)C1***21CC1 Chemical compound C*OC1C2(CO*)OC(*)C1***21CC1 0.000 description 5
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562126439P | 2015-02-27 | 2015-02-27 | |
| US62/126,439 | 2015-02-27 | ||
| PCT/US2016/019728 WO2016138355A1 (en) | 2015-02-27 | 2016-02-26 | Modulation of apolipoprotein c-iii (apociii) expression in lipodystrophy populations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018511555A JP2018511555A (ja) | 2018-04-26 |
| JP2018511555A5 true JP2018511555A5 (https=) | 2020-06-18 |
Family
ID=56789093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017538667A Pending JP2018511555A (ja) | 2015-02-27 | 2016-02-26 | リポジストロフィー集団におけるアポリポタンパク質Ｃ−ＩＩＩ（ＡｐｏＣＩＩＩ）発現の調節 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20180245076A1 (https=) |
| EP (1) | EP3270931A4 (https=) |
| JP (1) | JP2018511555A (https=) |
| KR (1) | KR20170122769A (https=) |
| CN (1) | CN107405358A (https=) |
| AU (1) | AU2016222548A1 (https=) |
| BR (1) | BR112017015307A2 (https=) |
| CA (1) | CA2977971A1 (https=) |
| HK (1) | HK1248522A1 (https=) |
| IL (1) | IL253346A0 (https=) |
| MX (1) | MX2017011009A (https=) |
| RU (1) | RU2737719C2 (https=) |
| WO (1) | WO2016138355A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3036551A1 (en) | 2016-09-12 | 2018-03-15 | Aegerion Pharmaceuticals, Inc. | Methods of detecting anti-leptin neutralizing antibodies |
| EP4035659A1 (en) | 2016-11-29 | 2022-08-03 | PureTech LYT, Inc. | Exosomes for delivery of therapeutic agents |
| IL300882A (en) * | 2020-10-02 | 2023-04-01 | Ionis Pharmaceuticals Inc | Methods for reducing APOCIII expression |
| CN117580953B (zh) * | 2021-07-16 | 2025-07-18 | 苏州瑞博生物技术股份有限公司 | 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7598227B2 (en) * | 2003-04-16 | 2009-10-06 | Isis Pharmaceuticals Inc. | Modulation of apolipoprotein C-III expression |
| EP3009136A1 (en) * | 2011-01-31 | 2016-04-20 | Cadila Healthcare Limited | Treatment for lipodystrophy |
| CN107854478A (zh) * | 2011-04-27 | 2018-03-30 | Ionis制药公司 | 载脂蛋白ciii（apociii）表达的调节 |
| AU2014216137B2 (en) * | 2013-02-14 | 2018-05-10 | Ionis Pharmaceuticals, Inc. | Modulation of Apolipoprotein C-III (ApoCIII) expression in lipoprotein lipase deficient (LPLD) populations |
| WO2014205449A2 (en) * | 2013-06-21 | 2014-12-24 | Isis Pharmaceuticals, Inc. | Compounds and methods for modulating apolipoprotein c-iii expression for improving a diabetic profile |
| US20150045431A1 (en) * | 2013-08-06 | 2015-02-12 | Amarin Pharmaceuticals Ireland Limited | Methods of treating a cardiovascular disorder in a subject on apo-c3 modulating therapy |
-
2016
- 2016-02-26 JP JP2017538667A patent/JP2018511555A/ja active Pending
- 2016-02-26 RU RU2017133142A patent/RU2737719C2/ru active
- 2016-02-26 BR BR112017015307A patent/BR112017015307A2/pt not_active Application Discontinuation
- 2016-02-26 AU AU2016222548A patent/AU2016222548A1/en not_active Abandoned
- 2016-02-26 CN CN201680009110.1A patent/CN107405358A/zh active Pending
- 2016-02-26 HK HK18107740.8A patent/HK1248522A1/zh unknown
- 2016-02-26 US US15/553,946 patent/US20180245076A1/en not_active Abandoned
- 2016-02-26 KR KR1020177025758A patent/KR20170122769A/ko not_active Ceased
- 2016-02-26 EP EP16756424.4A patent/EP3270931A4/en not_active Withdrawn
- 2016-02-26 MX MX2017011009A patent/MX2017011009A/es unknown
- 2016-02-26 CA CA2977971A patent/CA2977971A1/en not_active Abandoned
- 2016-02-26 WO PCT/US2016/019728 patent/WO2016138355A1/en not_active Ceased
-
2017
- 2017-07-06 IL IL253346A patent/IL253346A0/en unknown
-
2019
- 2019-07-31 US US16/528,387 patent/US20200095581A1/en not_active Abandoned
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