JP2018509254A - 寒冷麻酔及び鎮痛剤用のアプリケーター - Google Patents
寒冷麻酔及び鎮痛剤用のアプリケーター Download PDFInfo
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Abstract
Description
本願は、2015年10月6日に出願された米国仮出願第62/237,793号及び2015年3月26日に出願された米国仮出願第62/138,444号の利益を主張する。これらの出願の開示の全体が参照によって本明細書に組み込まれる。
Claims (27)
- 皮膚膜、粘膜又は皮膚粘膜領域の組織の標的範囲を冷却する装置であって、
使用者による手持ち操作を容易にする把持部、並びに基端部及び先端部を有する長尺体と、
前記長尺体の少なくとも一部内に設置され、寒冷麻酔又は鎮痛剤を誘導するために前記標的範囲に物理的に接触して熱的に結合するように構成された熱電冷却システムとを備えており、前記熱電冷却システムが、
前記標的範囲と熱的に接触するようになっており、前記長尺体の前記先端部上に設置されている熱伝導性の低温ティップと、
前記低温ティップに熱的に結合する熱伝導性の冷却力集中器と、
前記冷却力集中器に熱的に結合し、前記冷却力集中器の冷却を誘導するように機能する少なくとも1つのペルティエユニットモジュールと、
電源と、
前記低温ティップ、前記冷却力集中器、前記ペルティエユニットモジュール、周囲環境及び標的範囲の少なくとも1つの温度又は熱流束を検出し、温度信号又は熱流束信号を出力する熱センサーと、
前記温度信号又は前記熱流束信号、及び所定の温度又は熱流束に応えて、前記ペルティエユニットモジュールに制御信号を操作可能に出力する制御部と、
前記ペルティエユニットモジュールに熱的に結合するヒートシンクとを有する、装置。 - 前記少なくとも1つのペルティエユニットモジュールが複数のペルティエユニットモジュールを備える、請求項1に記載の装置。
- 前記複数のペルティエユニットモジュールが並列配列で電気的に結合する、請求項2に記載の装置。
- 前記複数のペルティエユニットモジュールが直列配列で電気的に結合する、請求項2に記載の装置。
- 前記複数のペルティエユニットモジュールが部分的に並列且つ部分的に直列な配列で電気的に結合する、請求項2に記載の装置。
- 前記冷却力集中器が、断面が概して矩形状の長尺集中器であり、前記長尺集中器の側に前記少なくとも1つのペルティエユニットモジュールが設置されている、請求項1に記載の装置。
- 前記冷却力集中器が前記長尺体の縦軸線に沿って延在する、請求項1に記載の装置。
- 前記低温ティップが、その上に、前記標的範囲上に一時的な目印を設けるように構成されて形成された標的目印を備える、請求項1に記載の装置。
- 前記標的目印が、前記標的範囲上に一時的な圧痕を設けるための一対の突起を備える、請求項8に記載の装置。
- 前記長尺体内に設置されて前記ヒートシンクを通る空気の通過を促すことで熱伝導を促進するファン部材を有する空気循環システムを更に備える、請求項1に記載の装置。
- 前記空気循環システムが、
前記長尺体の前記先端部上の前記低温ティップに隣接して設置される吸気口と、
前記ヒートシンクから延在する複数のフィン流路と、
前記吸気口に対して前記長尺体の前記基端部に向かう位置において、前記長尺体を通って延在する排気口とを備える、請求項10に記載の装置。 - 前記空気循環システムが、
前記長尺体の前記先端部上の前記低温ティップに隣接して設置される排気口と、
前記ヒートシンクから延在する複数のフィン流路と、
前記排気口に対して前記長尺体の前記基端部に向かう位置において、前記長尺体を通って延在する吸気口とを備える、請求項10に記載の装置。 - 前記複数のフィン流路が、前記長尺体の前記把持部によって全体的に囲まれ、前記複数のフィン流路に沿った空気流が、前記長尺体の縦軸線に対して全体的に平行である、請求項11に記載の装置。
- 前記複数のフィン流路が前記ヒートシンクから径方向に延在する、請求項11に記載の装置。
- 前記冷却力集中器が圧縮性端部を備え、前記圧縮性端部が、そこから延在して前記低温ティップを前記冷却力集中器に機械的、熱的及び取り外し可能に結合できる大きさをもつ複数のフランジ部材を有する、請求項1に記載の装置。
- 前記圧縮性ティップが、前記複数のフランジ部材を螺合する圧縮リングを備え、前記複数のフランジ部材と前記低温ティップとの係合を促す、請求項15に記載の装置。
- 前記低温ティップを取り囲んで設置され、前記低温ティップと前記標的範囲との直接的な物理的接触を防止し且つ前記低温ティップと前記標的範囲との熱的な結合を許容するように前記低温ティップを覆うカバーを更に備える、請求項1に記載の装置。
- 前記カバーの表面が疎水性である、請求項17に記載の装置。
- 前記低温ティップの周辺を全体的に囲むことで、前記標的範囲の外側における隣接する細胞の熱暴露を軽減する断熱リングを更に備える、請求項1に記載の装置。
- 前記断熱リングが能動加熱素子を備える、請求項19に記載の装置。
- 前記電源が携帯可能な電源である、請求項1に記載の装置。
- 前記長尺体の前記把持部が前記長尺体の基部よりも細長く、前記基部が前記基端部に隣接する、請求項1に記載の装置。
- 廃棄可能な針と、
シリンジと、
前記針を前記標的範囲内へ前進させて前記シリンジから前記標的範囲内へ液体を注入するシリンジプランジャーと、
注入が完了すると前記針を前記装置へと引き戻す後退要素とを備えている注入機構を含む、請求項1に記載の装置。 - 注入を作動させるスイッチを含む、請求項1に記載の装置。
- 前記低温装置ティップが殺菌消毒剤で覆われて消毒されている、請求項1に記載の装置。
- 前記装置低温ティップが、組織を保持するための湾曲した支持部を有する、請求項1に記載の装置。
- 皮膚膜、粘膜又は皮膚粘膜領域の組織の標的範囲に寒冷麻酔又は鎮痛剤を施す方法であって、
使用者による手持ち操作を容易にする把持部、並びに基端部及び先端部を有する長尺体と、
前記長尺体の少なくとも一部内に設置され、寒冷麻酔又は鎮痛剤を誘導するために前記標的範囲に物理的に接触して熱的に結合するように構成された熱電冷却システムとを備えており、前記熱電冷却システムが、
前記標的範囲と熱的に接触するようになっており、前記長尺体の前記先端部上に設置されている熱伝導性の低温ティップと、
前記低温ティップに熱的に結合する熱伝導性の冷却力集中器と、
前記冷却力集中器に熱的に結合し、前記冷却力集中器の冷却を誘導するように機能する少なくとも1つのペルティエユニットモジュールと、
電源と、
前記低温ティップ、前記冷却力集中器、前記ペルティエユニットモジュール、周囲環境及び標的範囲の少なくとも1つの温度又は熱流束を検出し、温度信号又は熱流束信号を出力する熱センサーと、
前記温度信号又は前記熱流束信号、及び所定の温度又は熱流束に応えて、前記ペルティエユニットモジュールに制御信号を操作可能に出力する制御部と、
前記ペルティエユニットモジュールに熱的に結合するヒートシンクとを有する、装置を設けることと、
前記低温ティップを前記標的範囲の上にあてがう前又はそれと同時に前記低温ティップを所定の温度まで冷却することを実現するように前記制御部を動作させることと、
前記標的範囲を寒冷麻酔又は鎮痛するために前記標的範囲の十分な冷却を実現することとを備えている、方法。
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- 2016-03-24 CN CN202210829092.9A patent/CN115300218A/zh active Pending
- 2016-03-24 JP JP2017550209A patent/JP2018509254A/ja active Pending
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- 2016-03-24 CN CN201680024232.8A patent/CN107530185A/zh active Pending
- 2016-03-24 EP EP16769665.7A patent/EP3273921A4/en active Pending
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- 2016-03-24 KR KR1020177029464A patent/KR102589046B1/ko active IP Right Grant
- 2016-03-24 AU AU2016235124A patent/AU2016235124B2/en not_active Ceased
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2017
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2018
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2019
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AU2016235124B2 (en) | 2020-10-22 |
US10322248B2 (en) | 2019-06-18 |
JP2021058626A (ja) | 2021-04-15 |
US10238814B2 (en) | 2019-03-26 |
KR20230146668A (ko) | 2023-10-19 |
KR20170130470A (ko) | 2017-11-28 |
CN107530185A (zh) | 2018-01-02 |
CA2980936A1 (en) | 2016-09-29 |
US20190167916A1 (en) | 2019-06-06 |
SG11201707880YA (en) | 2017-10-30 |
NZ735836A (en) | 2019-07-26 |
WO2016154399A1 (en) | 2016-09-29 |
EP3273921A4 (en) | 2018-10-10 |
HK1247805A1 (zh) | 2018-10-05 |
EP3273921A1 (en) | 2018-01-31 |
US9956355B2 (en) | 2018-05-01 |
US20160279350A1 (en) | 2016-09-29 |
KR102589046B1 (ko) | 2023-10-13 |
US20170304558A1 (en) | 2017-10-26 |
US20190015602A1 (en) | 2019-01-17 |
US20220379043A1 (en) | 2022-12-01 |
BR112017020520A2 (pt) | 2018-07-10 |
CN115300218A (zh) | 2022-11-08 |
US11389600B2 (en) | 2022-07-19 |
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