JP2018508243A - 吸収性接着剤シーラント層を有する負圧創傷ドレッシング - Google Patents
吸収性接着剤シーラント層を有する負圧創傷ドレッシング Download PDFInfo
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- JP2018508243A JP2018508243A JP2017535053A JP2017535053A JP2018508243A JP 2018508243 A JP2018508243 A JP 2018508243A JP 2017535053 A JP2017535053 A JP 2017535053A JP 2017535053 A JP2017535053 A JP 2017535053A JP 2018508243 A JP2018508243 A JP 2018508243A
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- porous layer
- wound dressing
- adhesive gel
- layer
- absorbent
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Abstract
Description
本出願は、2014年12月30日付出願の米国仮特許出願公開第62/098,058号、及び2015年2月6日付出願の同第62/112,714号に対する優先権を主張し、これらの開示は、本明細書においてその全体を組み込まれる。
代表的な実施形態
第1主面、第2主面、支持層周辺部、及び第1開口部を有する、湿分透過性支持層であって、
第2主面は支持層周辺部付近でその上に第1接着剤を有する、湿分透過性支持層と、
支持層の第2主面の少なくとも一部に接着した吸収性接着剤ゲルであって、接着剤ゲル周辺部を備える、吸収性接着剤ゲルと、
第1面、第2面、及び多孔性層周辺部を有する多孔性層と、を備え、
多孔性層の第1面は吸収性接着剤ゲルに接着しており、
多孔性層は流体が第2開口部へと通過するのを容易にするように構成されており、
接着剤ゲル周辺部の100%が支持層と重なりあい、
多孔性層周辺部の少なくとも50%は吸収性接着剤ゲルと重なりあっている、創傷ドレッシングである。
多孔性層は多孔性層周辺部により画定される多孔性層領域を有し、
多孔性層は少なくとも1つの開放領域を含み、
開放領域の合計は、多孔性層領域の5%以上、かつ50%以下である、先行する実施形態のいずれか1つに記載の創傷ドレッシングである。
多孔性層は多孔性層周辺部により画定される多孔性層領域を有し、
多孔性層は複数の開放領域を含み、各開放領域は多孔性層領域の5%以上、かつ50%以下である、先行する実施形態のいずれか1つに記載の創傷ドレッシングである。
鋼鉄への接着試験は、光沢のあるアニール仕上げの304AISIステンレススチールプレートを使用して行われた。プレートの寸法は51mm×127mm×1.6mmであった。試験表面は、各試験の前に、イソプロパノールを満たした使い捨ての実験用拭き取り布を使用して1回、及びn−ヘプタンを満たした使い捨て実験用拭き取り布で3回清浄化した。表面は、サンプルを試験表面上に配置する前に乾燥させた。試験試料の丈は1インチ幅であった。接着力を測定する前に、同じサンプルの接着面を鋼鉄プレートに手で押し付け、サンプルの非接着面は各方向に一度ローラを転がして、接着面をプレートに対して押し付けた。ローラは、全直径が3.75インチ(95mm)、面幅が1.75インチ(44mm)であり、75〜85デュロメータの硬さのゴムが厚さ約0.25インチ(6mm)で被覆され、4.5ポンド、すなわち2043グラムの有効ローリング重量を有した。ロール速度はおよそ50mm/秒であった。サンプルは、305mm/分の速度で180°剥離を使用して、ロールした直後に試験された。試験は、25℃及び50%の相対湿度での室内にて行われた。
Claims (20)
- 第1主面、第2主面、支持層周辺部、及び第1開口部を有する湿分透過性支持層であって、
前記第2主面は前記支持層周辺部付近でその上に第1接着剤を有する、湿分透過性支持層と、
前記支持層の前記第2主面の少なくとも一部に接着した吸収性接着剤ゲルであって、接着剤ゲル周辺部を備える吸収性接着剤ゲルと、
第1面、第2面、及び多孔性層周辺部を有する多孔性層と、を備え、
前記多孔性層の前記第1面は前記吸収性接着剤ゲルに接着しており、
前記多孔性層は流体が第2開口部へと通過するのを容易にするように構成されており、
前記接着剤ゲル周辺部の100%が前記支持層と重なりあい、
前記多孔性層周辺部の少なくとも50%は前記吸収性接着剤ゲルと重なりあっている、創傷ドレッシング。 - 前記吸収性接着剤ゲルは第2開口部を更に含む、請求項1に記載の創傷ドレッシング。
- 前記吸収性接着剤ゲルが約0.2mm〜約4.0mmの厚さを有する、請求項1又は2に記載の創傷ドレッシング。
- 前記吸収性接着剤ゲルが40重量%未満の水を含む、請求項1〜3のいずれか一項に記載の創傷ドレッシング。
- 前記多孔性層は前記多孔性層周辺部により画定される多孔性層領域を有し、
前記多孔性層は少なくとも1つの開放領域を含み、
前記少なくとも1つの開放領域は前記多孔性層領域の5%以上、かつ50%以下である、請求項1〜4のいずれか一項に記載の創傷ドレッシング。 - 前記多孔性層は前記多孔性層周辺部により画定される多孔性層領域を有し、
前記多孔性層は複数の開放領域を含み、各開放領域は前記多孔性層領域の5%以上、かつ50%以下である、請求項1〜5のいずれか一項に記載の創傷ドレッシング。 - 前記開放領域の少なくとも1つが前記多孔性層領域の5%以上、かつ20%以下である、請求項5又は6に記載の創傷ドレッシング。
- 前記ドレッシングは、前記多孔性層の前記第2面に接着された穿孔層を更に備える、請求項1〜7のいずれか一項に記載の創傷ドレッシング。
- 前記穿孔層は、前記多孔性層の前記第2面に面する第1主面と、前記第1主面と反対側の第2主面とを有し、前記第2主面はシリコーン接着剤を含む、請求項8に記載の創傷ドレッシング。
- 前記支持層に接着した前記吸収性接着剤ゲルの鋼鉄に対する接着が、前記多孔性層に接着された前記シリコーン接着剤の鋼鉄に対する接着よりも強い、請求項9に記載の創傷ドレッシング。
- 前記支持層に接着した前記吸収性接着剤ゲルの鋼鉄に対する接着が、前記支持層に接着された前記第1接着剤の鋼鉄に対する接着よりも強い、請求項9又は10に記載の創傷ドレッシング。
- 前記支持層がポリマー弾性フィルム、弾性不織布、又はその組み合わせを含む、請求項1〜11のいずれか一項に記載の創傷ドレッシング。
- 前記支持層が、EN−13726−1:2002セクション3.3によって測定したときに10g/10cm2/24時間以上の水蒸気透過速度を有する、請求項1〜12のいずれか一項に記載の創傷ドレッシング。
- 前記吸収性接着剤ゲルが接着された前記支持層が、EN−13726−1:2002セクション3.3によって測定したときに1g/10cm2/24時間以上の水蒸気透過速度を有する、請求項1〜13のいずれか一項に記載の創傷ドレッシング。
- 前記吸収性接着剤ゲルは、24℃、1rad/秒の剪断において、約5,000パスカル〜約50,000パスカルの剪断弾性率を有する、請求項1〜14のいずれか一項に記載の創傷ドレッシング。
- 前記吸収性接着剤ゲルは、24℃、1rad/秒の剪断において、約2,000パスカル〜約20,000パスカルの損失剪断弾性率を有する、請求項1〜15のいずれか一項に記載の創傷ドレッシング。
- 前記吸収性接着剤ゲルが抗菌剤を更に含む、請求項1〜16のいずれか一項に記載の創傷ドレッシング。
- 前記多孔性吸収性層は、連続気泡発泡体、織布、不織布、多孔性フィルム、又はこれらの組み合わせを含む、請求項1〜17のいずれか一項に記載の創傷ドレッシング。
- 前記吸収性接着剤ゲルが37℃で24時間にわたり、等張性生理食塩水と接触させられた際にその乾燥重量の1.5倍以上を吸収することができる、請求項1〜18のいずれか一項に記載の創傷ドレッシング。
- 真空ポートを更に備える、請求項1〜19のいずれか一項に記載の創傷ドレッシング。
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US62/112,714 | 2015-02-06 | ||
PCT/US2015/067661 WO2016109420A1 (en) | 2014-12-30 | 2015-12-28 | Negative pressure wound dressing with absorbent adhesive sealant layer |
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CN107106723A (zh) | 2017-08-29 |
US10537478B2 (en) | 2020-01-21 |
JP2018500137A (ja) | 2018-01-11 |
EP3240581B1 (en) | 2020-04-15 |
CN107106334A (zh) | 2017-08-29 |
US20200107967A1 (en) | 2020-04-09 |
EP3240580A1 (en) | 2017-11-08 |
WO2016109420A1 (en) | 2016-07-07 |
CN107106723B (zh) | 2020-10-23 |
EP3240580B1 (en) | 2020-04-15 |
US20170367895A1 (en) | 2017-12-28 |
CN107106334B (zh) | 2021-02-09 |
WO2016109418A1 (en) | 2016-07-07 |
US20170367896A1 (en) | 2017-12-28 |
US11007086B2 (en) | 2021-05-18 |
JP6838812B2 (ja) | 2021-03-03 |
EP3240581A1 (en) | 2017-11-08 |
JP6744315B2 (ja) | 2020-08-19 |
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