JP2018504418A - 癌を治療するためのirs/stat3二重修飾因子と抗癌剤の組み合わせ - Google Patents

癌を治療するためのirs/stat3二重修飾因子と抗癌剤の組み合わせ Download PDF

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JP2018504418A
JP2018504418A JP2017539669A JP2017539669A JP2018504418A JP 2018504418 A JP2018504418 A JP 2018504418A JP 2017539669 A JP2017539669 A JP 2017539669A JP 2017539669 A JP2017539669 A JP 2017539669A JP 2018504418 A JP2018504418 A JP 2018504418A
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compound
combination
formula
tumor
cancer
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JP2018504418A5 (enExample
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リューベニ,ハダス
ハビブ,イズハック
クーパーシュミドト,ラナ
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ティルノーヴォ リミテッド
ティルノーヴォ リミテッド
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    • A61K31/4164—1,3-Diazoles
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    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
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JP2017539669A 2015-02-05 2016-02-04 癌を治療するためのirs/stat3二重修飾因子と抗癌剤の組み合わせ Pending JP2018504418A (ja)

Priority Applications (1)

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JP2021011512A JP7624700B2 (ja) 2015-02-05 2021-01-27 癌を治療するためのirs/stat3二重修飾因子と抗癌剤の組み合わせ

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US201562112257P 2015-02-05 2015-02-05
US62/112,257 2015-02-05
US201562136530P 2015-03-22 2015-03-22
US62/136,530 2015-03-22
PCT/IL2016/050134 WO2016125169A1 (en) 2015-02-05 2016-02-04 Combinations of irs/stat3 dual modulators and anti-cancer agents for treating cancer

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JP2021011512A Division JP7624700B2 (ja) 2015-02-05 2021-01-27 癌を治療するためのirs/stat3二重修飾因子と抗癌剤の組み合わせ

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JP2018504418A true JP2018504418A (ja) 2018-02-15
JP2018504418A5 JP2018504418A5 (enExample) 2019-03-14

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JP2017539669A Pending JP2018504418A (ja) 2015-02-05 2016-02-04 癌を治療するためのirs/stat3二重修飾因子と抗癌剤の組み合わせ
JP2021011512A Active JP7624700B2 (ja) 2015-02-05 2021-01-27 癌を治療するためのirs/stat3二重修飾因子と抗癌剤の組み合わせ
JP2023027482A Pending JP2023062187A (ja) 2015-02-05 2023-02-24 癌を治療するためのirs/stat3二重修飾因子と抗癌剤の組み合わせ

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JP2021011512A Active JP7624700B2 (ja) 2015-02-05 2021-01-27 癌を治療するためのirs/stat3二重修飾因子と抗癌剤の組み合わせ
JP2023027482A Pending JP2023062187A (ja) 2015-02-05 2023-02-24 癌を治療するためのirs/stat3二重修飾因子と抗癌剤の組み合わせ

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US (3) US10912745B2 (enExample)
EP (2) EP3253733B1 (enExample)
JP (3) JP2018504418A (enExample)
KR (1) KR20170109589A (enExample)
CN (3) CN107250108B (enExample)
AU (2) AU2016213972B2 (enExample)
ES (2) ES3064856T3 (enExample)
IL (2) IL253797B (enExample)
WO (1) WO2016125169A1 (enExample)

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TWI852912B (zh) 2017-09-07 2024-08-21 美商銳新醫藥公司 Shp2抑制劑組合物以及治療癌症的方法
BR112020007058A2 (pt) 2017-10-12 2020-10-06 Revolution Medicines, Inc. compostos de piridina, pirazina, e triazina como inibidores de shp2 alostéricos
US20200369607A1 (en) * 2017-11-16 2020-11-26 Tyrnovo Ltd. Combinations of irs/stat3 dual modulators and anti pd-1/pd-l1 antibodies for treating cancer
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JP7386174B2 (ja) * 2018-03-27 2023-11-24 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム Her2エクソン19変異を有するがん細胞に対する抗腫瘍活性を有する化合物
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KR102980990B1 (ko) 2019-04-05 2026-06-25 카이메라 쎄라퓨틱스 인코포레이티드 Stat 분해제 및 이의 용도
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