JP2018504409A - 疾患および障害の治療方法および組成物 - Google Patents
疾患および障害の治療方法および組成物 Download PDFInfo
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Abstract
Description
である。
以下の定義は、本発明の理解を促すために提供される。
Claims (17)
- それを必要とする患者の炎症性腸疾患を治療、阻害、および/または予防する方法であって、前記患者に少なくとも1つの抗Bin1抗体またはそのフラグメントを投与する工程を有する、方法。
- 請求項1記載の方法であって、少なくとも1つの抗Bin1抗体またはそのフラグメントと、少なくとも1つの薬学的に許容される担体とを有する組成物を投与する工程を有する、方法。
- 請求項1記載の方法において、前記抗Bin1抗体は、Bin1のMyc結合ドメインに免疫学的に特異的である、方法。
- 請求項1記載の方法において、前記抗Bin1抗体は、配列ID番号:2に免疫学的に特異的である、方法。
- 請求項1記載の方法において、前記炎症性腸疾患は、潰瘍性大腸炎またはクローン病である、方法。
- 請求項1記載の方法であって、さらに、少なくとも1つの抗炎症薬の投与を有する、方法。
- それを必要とする患者の大腸癌を治療、阻害、および/または予防する方法であって、前記患者に少なくとも1つの抗Bin1抗体またはそのフラグメントを投与する工程を有する、方法。
- 請求項7記載の方法であって、少なくとも1つの抗Bin1抗体またはそのフラグメントと、少なくとも1つの薬学的に許容される担体とを有する組成物を投与する工程を有する、方法。
- 請求項7記載の方法において、前記抗Bin1抗体は、Bin1のMyc結合ドメインに免疫学的に特異的である、方法。
- 請求項7記載の方法において、前記抗Bin1抗体は、配列ID番号:2に免疫学的に特異的である、方法。
- 請求項7記載の方法であって、さらに、少なくとも1つの化学療法剤の投与を有する、方法。
- それを必要とする患者の神経変性疾患を治療する方法であって、前記患者に少なくとも1つの抗Bin1抗体またはそのフラグメントを投与する工程を有する、方法。
- 請求項12記載の方法であって、少なくとも1つの抗Bin1抗体またはそのフラグメントと、少なくとも1つの薬学的に許容される担体とを有する組成物を投与する工程を有する、方法。
- 請求項12記載の方法において、前記抗Bin1抗体は、Bin1のMyc結合ドメインに免疫学的に特異的である、方法。
- 請求項12記載の方法において、前記抗Bin1抗体は、配列ID番号:2に免疫学的に特異的である、方法。
- 請求項12記載の方法において、前記神経変性疾患はタウノパチーである、方法。
- 請求項12記載の方法において、前記神経変性疾患はアルツハイマー病である、方法。
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