JP2018501201A5 - - Google Patents

Download PDF

Info

Publication number
JP2018501201A5
JP2018501201A5 JP2017526674A JP2017526674A JP2018501201A5 JP 2018501201 A5 JP2018501201 A5 JP 2018501201A5 JP 2017526674 A JP2017526674 A JP 2017526674A JP 2017526674 A JP2017526674 A JP 2017526674A JP 2018501201 A5 JP2018501201 A5 JP 2018501201A5
Authority
JP
Japan
Prior art keywords
seq
polypeptide
amino acid
acid sequence
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2017526674A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018501201A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from US14/943,752 external-priority patent/US10500249B2/en
Publication of JP2018501201A publication Critical patent/JP2018501201A/ja
Publication of JP2018501201A5 publication Critical patent/JP2018501201A5/ja
Pending legal-status Critical Current

Links

JP2017526674A 2014-11-17 2015-11-17 異常な線維芽細胞増殖および細胞外マトリックス沈着を特徴とする疾患、状態、またはプロセスを予防または処置するための組成物および方法 Pending JP2018501201A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462080784P 2014-11-17 2014-11-17
US62/080,784 2014-11-17
US14/943,752 2015-11-17
US14/943,752 US10500249B2 (en) 2014-11-17 2015-11-17 Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
PCT/US2015/061118 WO2016081475A1 (en) 2014-11-17 2015-11-17 Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition

Publications (2)

Publication Number Publication Date
JP2018501201A JP2018501201A (ja) 2018-01-18
JP2018501201A5 true JP2018501201A5 (enExample) 2018-12-27

Family

ID=55960752

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017526674A Pending JP2018501201A (ja) 2014-11-17 2015-11-17 異常な線維芽細胞増殖および細胞外マトリックス沈着を特徴とする疾患、状態、またはプロセスを予防または処置するための組成物および方法

Country Status (13)

Country Link
US (1) US10500249B2 (enExample)
EP (1) EP3220943A4 (enExample)
JP (1) JP2018501201A (enExample)
KR (1) KR20170083063A (enExample)
CN (1) CN107106650A (enExample)
AU (1) AU2015350151A1 (enExample)
BR (1) BR112017010238A2 (enExample)
CA (1) CA2967621A1 (enExample)
MX (1) MX2017006372A (enExample)
RU (1) RU2017121090A (enExample)
SG (1) SG11201703939XA (enExample)
WO (1) WO2016081475A1 (enExample)
ZA (1) ZA201703305B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111050786A (zh) * 2017-09-08 2020-04-21 百时美施贵宝公司 用于治疗非酒精性脂肪性肝炎(nash)的方法的修饰的成纤维细胞生长因子21(fgf-21)
EP3692073A4 (en) 2017-10-03 2021-05-26 Cedars-Sinai Medical Center METHOD OF TARGETING THE IMMUNE CHECK POINT PD1 SIGNAL PATH FOR TREATMENT OF LUNG FIBROSIS
CN108795935B (zh) * 2018-05-23 2022-06-21 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 日本血吸虫SjELAV-like 1基因的siRNA及其应用
CN110575540B (zh) * 2018-06-07 2021-11-02 中山大学附属第六医院 Pdgf抑制剂用于制备治疗肠道炎症疾病的药物方面的用途
CN113134116B (zh) * 2020-01-20 2022-09-06 山东威高宏瑞医学科技有限公司 内镜微创手术用的填充组合物及填充制剂
CN113952821A (zh) * 2021-07-22 2022-01-21 上海安居乐环保科技股份有限公司 一种罐区装卸区废气综合治理方法及系统
CN113730551B (zh) * 2021-09-02 2022-11-25 徐州医科大学 Mmi-0100短肽化合物在制备胆汁淤积性肝病治疗药物中的应用
CN118388635B (zh) * 2024-06-24 2024-10-11 山东美瑞生物技术有限公司 一种提高皮肤修复功能的重组人源化胶原蛋白的制备方法
CN118571492B (zh) * 2024-08-02 2024-10-18 天津市胸科医院 基于组织边界影响的主动脉夹层患者并发症风险预测模型

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1521000A (en) 1975-06-13 1978-08-09 Syntex Puerto Rico Inc Inhalation device
US4192309A (en) 1978-09-05 1980-03-11 Syntex Puerto Rico, Inc. Inhalation device with capsule opener
US4227522A (en) 1978-09-05 1980-10-14 Syntex Puerto Rico, Inc. Inhalation device
US4778054A (en) 1982-10-08 1988-10-18 Glaxo Group Limited Pack for administering medicaments to patients
DK172541B1 (da) 1982-10-08 1998-12-07 Glaxo Group Ltd Apparat til administrering af medikamenter til patienter og en medikamentpakning til brug i apparatet
AU591152B2 (en) 1985-07-30 1989-11-30 Glaxo Group Limited Devices for administering medicaments to patients
JPH05963A (ja) 1990-04-13 1993-01-08 Toray Ind Inc ポリペプチド類組成物
US6331318B1 (en) 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
US5352461A (en) 1992-03-11 1994-10-04 Pharmaceutical Discovery Corporation Self assembling diketopiperazine drug delivery system
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
DK0733059T3 (da) 1993-12-09 2000-10-16 Univ Jefferson Forbindelser og fremgangsmåder til site-rettede mutationer i eukaryote celler
US6428771B1 (en) 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
DK1165050T3 (da) 1999-04-05 2006-05-01 Mannkind Corp Fremgangsmåde til dannelse af fint pulver
ES2395096T3 (es) 1999-06-29 2013-02-08 Mannkind Corporation Purificación y estabilización de agentes farmacéuticos a base de péptidos y proteínas
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
HUE025151T2 (en) 2004-08-23 2016-01-28 Mannkind Corp Diceto-piperazine salts for drug delivery
BRPI0514410A (pt) 2004-08-23 2008-06-10 Mannkind Corp fornecimento pulmonar de inibidores de fosfodiesterase do tipo 5
MX373000B (es) 2005-09-14 2020-05-21 Mannkind Corp Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas.
CN104383546B (zh) 2006-02-22 2021-03-02 曼金德公司 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法
ES2594281T3 (es) * 2007-01-10 2016-12-19 Purdue Research Foundation Inhibidores polipeptídicos de HSP27 quinasa y usos de los mismos
NL1033850C2 (nl) 2007-05-15 2008-11-18 3Force B V Brandersysteem met voorgemengde branders en vlam-overdrachtsmiddelen.
DK2185698T3 (en) 2007-08-07 2015-07-27 Purdue Research Foundation Kinase Inhibitors and Uses thereof
CN102256613B (zh) * 2008-10-20 2014-09-10 莫伊莱麦屈克斯公司 用于治疗或者预防粘连的多肽
US9327008B2 (en) * 2008-12-10 2016-05-03 Purdue Research Foundation Cell-permeant peptide-based inhibitor of kinases
EP2575855A4 (en) * 2010-05-24 2014-03-12 Moerae Matrix Inc METHOD FOR TREATING OR PREVENTING VASCULAR GRAFT BREAKAGE
CN108014340A (zh) * 2011-04-12 2018-05-11 莫伊莱麦屈克斯公司 用于预防或治疗以成纤维细胞异常增殖及细胞外基质沉积为特征的疾病的组合物和方法
WO2013134636A1 (en) * 2012-03-09 2013-09-12 Purdue Research Foundation Compositions and methods for delivery of kinase inhibiting peptides
US9750718B2 (en) * 2012-12-12 2017-09-05 The Charlotte-Mecklenburg Hospital Authority Methods of treating hepatic fibrosis and associated diseases by regulating Rev-ERB activity

Similar Documents

Publication Publication Date Title
RU2017121090A (ru) Композиции и способы для профилактики или лечения заболеваний, состояний или процессов, характеризующихся аберрантной пролиферацией фибробластов и накоплением внеклеточного матрикса
JP2014533235A5 (enExample)
Harrigan Angiogenic factors in the central nervous system
JP2020121984A (ja) 抗vegf抗体での治療
EP2170366B1 (en) Use of tlr-2 antagonists for treatment of reperfusion injury and tissue damage
CN108136025A (zh) 一种使用免疫调节治疗癌症的新颖方法
O'Brien et al. Evaluation of merocyanine 540-sensitized photoirradiation as a means to inactivate enveloped viruses in blood products
US20090263389A1 (en) Use of TGF-Beta Antagonists to Treat or to Prevent Chronic Transplant Rejection
RU2013150249A (ru) Композиции и способы профилактики или лечения заболеваний, состояний или процессов, характеризуемых аберрантной пролиферацией фибробластов и отложением внеклеточного матрикса
KR101780575B1 (ko) 신규한 인터루킨-33 수용체와 결합 단백질 조성물 및 그 용도
WO2020086580A1 (en) Therapeutic combinations of tdfrps and additional agents and methods of use
KR20170029576A (ko) 골형성단백질의 치료적 용도
US20240287153A1 (en) Treating Inflammatory Lung Disease
US20040266687A1 (en) Compositions and methods comprising protein activated receptor antagonists
KR20220015375A (ko) Sephb4-hsa 융합 단백질을 이용한 암의 치료
KR20160093076A (ko) 암의 치료용 조합 제조물
JPWO2012118042A1 (ja) 悪性腫瘍転移抑制用医薬
Zhao et al. Inhibition of tumor angiogenesis and tumor growth by the DSL domain of human Delta-like 1 targeted to vascular endothelial cells
JP2017509633A5 (enExample)
Ellmers et al. (Pro) renin receptor blockade ameliorates cardiac injury and remodeling and improves function after myocardial infarction
US11571455B2 (en) Methods and compositions for treating alcoholic liver disease
KR20110017362A (ko) 중피종 치료용 접합체
JP7182793B2 (ja) 病理学的腎組織損傷を予防及び治療するための方法
JP6782932B2 (ja) Npr−aアゴニストの新規用途
US20220143130A1 (en) Peptides Having Immunomodulatory Properties