JP2018500390A5 - - Google Patents
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- JP2018500390A5 JP2018500390A5 JP2017549860A JP2017549860A JP2018500390A5 JP 2018500390 A5 JP2018500390 A5 JP 2018500390A5 JP 2017549860 A JP2017549860 A JP 2017549860A JP 2017549860 A JP2017549860 A JP 2017549860A JP 2018500390 A5 JP2018500390 A5 JP 2018500390A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- wnt5a
- tumor
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462090029P | 2014-12-10 | 2014-12-10 | |
| US62/090,029 | 2014-12-10 | ||
| PCT/IB2015/002577 WO2016092378A1 (en) | 2014-12-10 | 2015-12-09 | Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brian tumors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018500390A JP2018500390A (ja) | 2018-01-11 |
| JP2018500390A5 true JP2018500390A5 (enExample) | 2019-01-24 |
| JP6921755B2 JP6921755B2 (ja) | 2021-08-18 |
Family
ID=55353245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017549860A Active JP6921755B2 (ja) | 2014-12-10 | 2015-12-09 | 脳腫瘍幹細胞の成長、遊走および浸潤性を低下させ脳腫瘍患者の生存率を改善する方法および組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10688167B2 (enExample) |
| EP (1) | EP3229831B1 (enExample) |
| JP (1) | JP6921755B2 (enExample) |
| KR (1) | KR102674191B1 (enExample) |
| AU (1) | AU2015359043C1 (enExample) |
| CA (1) | CA2970140A1 (enExample) |
| DK (1) | DK3229831T3 (enExample) |
| ES (1) | ES2796973T3 (enExample) |
| WO (1) | WO2016092378A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10852069B2 (en) | 2010-05-04 | 2020-12-01 | Fractal Heatsink Technologies, LLC | System and method for maintaining efficiency of a fractal heat sink |
| ES2796973T3 (es) * | 2014-12-10 | 2020-11-30 | Hyperstem Sa | Métodos y composiciones para reducir el crecimiento, la migración y la invasividad de células madre de cáncer cerebral y mejorar la supervivencia de pacientes con tumores cerebrales |
| EP3700546B1 (en) * | 2017-10-25 | 2023-08-16 | Wntresearch AB | Wnt5a peptides in reduction of cancer stem cells |
| KR101921836B1 (ko) | 2017-11-23 | 2018-11-26 | 서울대학교병원 | 피부성체 줄기세포의 분화 조절 방법, 및 피부성체 줄기세포의 분화 조절용 조성물 및 키트 |
| US20210041443A1 (en) * | 2018-04-24 | 2021-02-11 | Universidade Do Minho | Wnt6 as glioblastoma oncogenic biomarker, and uses of inhibitors thereof |
| EP3613757A1 (en) * | 2018-08-20 | 2020-02-26 | Wntresearch AB | Solution phase routes for wnt hexapeptides |
| EP3666789A1 (en) * | 2018-12-14 | 2020-06-17 | Wntresearch AB | Linear solution phase routes for wnt hexapeptides |
| US12678067B1 (en) | 2019-03-20 | 2026-07-14 | Biological Art Group, Inc. | Telemetry implants |
| EP3955950A1 (en) * | 2019-04-16 | 2022-02-23 | Wntresearch AB | Peptides in combination with immune checkpoint inhibitors for use in treatment of cancer |
| WO2021034784A1 (en) | 2019-08-16 | 2021-02-25 | Poltorak Technologies, LLC | Device and method for medical diagnostics |
| CN114081954B (zh) * | 2021-10-30 | 2023-02-28 | 中国人民解放军陆军军医大学第一附属医院 | 用于胶质母细胞瘤治疗的药物组合物以及预后的诊断试剂 |
| CN116173048B (zh) * | 2023-01-19 | 2026-06-16 | 温州医科大学附属第一医院 | 棉子糖及其衍生物在胶质母细胞瘤治疗中的应用 |
| WO2025088835A1 (ja) * | 2023-10-25 | 2025-05-01 | 国立大学法人大阪大学 | ヒト化抗ｃｋａｐ４抗体又はその抗原結合性断片 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1521000A (en) | 1975-06-13 | 1978-08-09 | Syntex Puerto Rico Inc | Inhalation device |
| US4192309A (en) | 1978-09-05 | 1980-03-11 | Syntex Puerto Rico, Inc. | Inhalation device with capsule opener |
| US4227522A (en) | 1978-09-05 | 1980-10-14 | Syntex Puerto Rico, Inc. | Inhalation device |
| US4778054A (en) | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
| DK172541B1 (da) | 1982-10-08 | 1998-12-07 | Glaxo Group Ltd | Apparat til administrering af medikamenter til patienter og en medikamentpakning til brug i apparatet |
| AU591152B2 (en) | 1985-07-30 | 1989-11-30 | Glaxo Group Limited | Devices for administering medicaments to patients |
| JPH05963A (ja) | 1990-04-13 | 1993-01-08 | Toray Ind Inc | ポリペプチド類組成物 |
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| EP1226172A1 (en) | 1999-11-05 | 2002-07-31 | Forskarpatent i Syd AB | Compounds, antibodies and methods for treating, preventing or diagnosing tumour metastasis |
| DK2384763T3 (en) | 2005-05-30 | 2015-07-20 | Wntres Ab | Peptide ligand for disrupting cancer cell migration |
| RU2517190C2 (ru) * | 2008-08-13 | 2014-05-27 | Внтрисерч Аб | Применение производных пептида wnt5-a для лечения меланомы и рака желудка |
| EP2523974A4 (en) * | 2010-01-12 | 2013-11-06 | Oncomed Pharm Inc | WNT BINDER AND APPLICATIONS THEREOF |
| EP2446895A1 (en) | 2010-10-01 | 2012-05-02 | Stemgen S.P.A. | EPH receptor expression in tumor stem cells |
| EP2726880B1 (en) * | 2011-07-01 | 2019-04-17 | Wntresearch AB | Treatment of prostate cancer and a method for determining the prognosis for prostate cancer patients |
| US20140171356A1 (en) * | 2012-12-12 | 2014-06-19 | The Board Of Trustees Of The Leland Stanford Junior University | Chemically immobilized wnt protein and methods of use |
| ES2796973T3 (es) * | 2014-12-10 | 2020-11-30 | Hyperstem Sa | Métodos y composiciones para reducir el crecimiento, la migración y la invasividad de células madre de cáncer cerebral y mejorar la supervivencia de pacientes con tumores cerebrales |
-
2015
- 2015-12-09 ES ES15834638T patent/ES2796973T3/es active Active
- 2015-12-09 AU AU2015359043A patent/AU2015359043C1/en active Active
- 2015-12-09 CA CA2970140A patent/CA2970140A1/en active Pending
- 2015-12-09 US US15/533,842 patent/US10688167B2/en active Active
- 2015-12-09 KR KR1020177018938A patent/KR102674191B1/ko active Active
- 2015-12-09 JP JP2017549860A patent/JP6921755B2/ja active Active
- 2015-12-09 WO PCT/IB2015/002577 patent/WO2016092378A1/en not_active Ceased
- 2015-12-09 DK DK15834638.7T patent/DK3229831T3/da active
- 2015-12-09 EP EP15834638.7A patent/EP3229831B1/en active Active
-
2020
- 2020-05-13 US US15/931,081 patent/US11357840B2/en active Active
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