JP2018500341A - 組み換えタンパク質の生産における収量改善法 - Google Patents
組み換えタンパク質の生産における収量改善法 Download PDFInfo
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- JP2018500341A JP2018500341A JP2017533632A JP2017533632A JP2018500341A JP 2018500341 A JP2018500341 A JP 2018500341A JP 2017533632 A JP2017533632 A JP 2017533632A JP 2017533632 A JP2017533632 A JP 2017533632A JP 2018500341 A JP2018500341 A JP 2018500341A
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- OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 description 1
- CILBMBUYJCWATM-PYGJLNRPSA-N vinorelbine ditartrate Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O.OC(=O)[C@H](O)[C@@H](O)C(O)=O.C1N(CC=2C3=CC=CC=C3NC=22)CC(CC)=C[C@H]1C[C@]2(C(=O)OC)C1=CC([C@]23[C@H]([C@@]([C@H](OC(C)=O)[C@]4(CC)C=CCN([C@H]34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC CILBMBUYJCWATM-PYGJLNRPSA-N 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
- PNAMDJVUJCJOIX-XVZWKFLSSA-N vytorin Chemical compound C([C@H]1[C@@H](C)C=CC2=C[C@H](C)C[C@@H]([C@H]12)OC(=O)C(C)(C)CC)C[C@@H]1C[C@@H](O)CC(=O)O1.N1([C@@H]([C@H](C1=O)CC[C@@H](O)C=1C=CC(F)=CC=1)C=1C=CC(O)=CC=1)C1=CC=C(F)C=C1 PNAMDJVUJCJOIX-XVZWKFLSSA-N 0.000 description 1
- 229940009349 vytorin Drugs 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- 229910052727 yttrium Inorganic materials 0.000 description 1
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5428—IL-10
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462096359P | 2014-12-23 | 2014-12-23 | |
| US62/096,359 | 2014-12-23 | ||
| PCT/US2015/067135 WO2016106229A1 (en) | 2014-12-23 | 2015-12-21 | Methods of improving yield in recombinant protein production |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018500341A true JP2018500341A (ja) | 2018-01-11 |
| JP2018500341A5 JP2018500341A5 (https=) | 2019-02-07 |
Family
ID=56151492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017533632A Withdrawn JP2018500341A (ja) | 2014-12-23 | 2015-12-21 | 組み換えタンパク質の生産における収量改善法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20170362291A1 (https=) |
| EP (1) | EP3237441A4 (https=) |
| JP (1) | JP2018500341A (https=) |
| CN (1) | CN107108712A (https=) |
| AU (1) | AU2015369808A1 (https=) |
| CA (1) | CA2969574A1 (https=) |
| HK (1) | HK1245297A1 (https=) |
| WO (1) | WO2016106229A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015336101A1 (en) | 2014-10-22 | 2017-04-20 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
| US10618970B2 (en) | 2015-02-03 | 2020-04-14 | Armo Biosciences, Inc. | Method of treating cancer with IL-10 and antibodies that induce ADCC |
| CA2986755A1 (en) | 2015-05-28 | 2016-12-01 | Armo Biosciences, Inc. | Pegylated interleukin-10 for use in treating cancer |
| US10398761B2 (en) | 2015-08-25 | 2019-09-03 | Armo Biosciences, Inc. | Methods of using combinations of PEG-IL-10 and IL-15 for treating cancers |
| KR20210110294A (ko) * | 2018-11-07 | 2021-09-07 | 어플라이드 몰레큘라 트랜스포트 인크. | 통과세포외배출용 전달 구조체 및 관련 방법 |
| EP3996787B1 (en) | 2019-07-09 | 2024-04-03 | O2Matic Aps | Device for regulating oxygen for automated oxygen therapy |
| CN114599665A (zh) | 2019-08-16 | 2022-06-07 | 应用分子转运公司 | 组合物、制剂及白细胞介素产生和纯化 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998020033A2 (en) * | 1996-11-06 | 1998-05-14 | Schering Corporation | RENATURATION AND PURIFICATION OF VIRAL INTERLEUKIN-10 (vIL-10) |
| CN1306030C (zh) * | 2001-09-28 | 2007-03-21 | 中山大学 | 一种人白细胞介素－10基因序列及含该基因序列的大肠杆菌 |
| WO2005033307A1 (ja) * | 2003-09-30 | 2005-04-14 | Kyowa Hakko Kogyo Co., Ltd. | 新規のリフォールディング方法およびその方法によって得られたタンパク質 |
| WO2007041713A1 (en) * | 2005-10-04 | 2007-04-12 | Zymogenetics, Inc. | Production and purification of il-29 |
| US20080125580A1 (en) * | 2006-07-14 | 2008-05-29 | Genentech, Inc. | Refolding of Recombinant Proteins |
| US8759617B2 (en) * | 2010-09-21 | 2014-06-24 | National Institute Of Agrobiological Sciences | Method for extraction and purification of recombinant proteins from transgenic plants |
-
2015
- 2015-12-21 CA CA2969574A patent/CA2969574A1/en not_active Abandoned
- 2015-12-21 HK HK18104785.1A patent/HK1245297A1/zh unknown
- 2015-12-21 AU AU2015369808A patent/AU2015369808A1/en not_active Abandoned
- 2015-12-21 US US15/532,254 patent/US20170362291A1/en not_active Abandoned
- 2015-12-21 JP JP2017533632A patent/JP2018500341A/ja not_active Withdrawn
- 2015-12-21 EP EP15874258.5A patent/EP3237441A4/en not_active Withdrawn
- 2015-12-21 CN CN201580073185.1A patent/CN107108712A/zh active Pending
- 2015-12-21 WO PCT/US2015/067135 patent/WO2016106229A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| HK1245297A1 (zh) | 2018-08-24 |
| AU2015369808A2 (en) | 2017-11-23 |
| WO2016106229A1 (en) | 2016-06-30 |
| EP3237441A1 (en) | 2017-11-01 |
| CA2969574A1 (en) | 2016-06-30 |
| EP3237441A4 (en) | 2018-06-06 |
| CN107108712A (zh) | 2017-08-29 |
| AU2015369808A1 (en) | 2017-06-29 |
| US20170362291A1 (en) | 2017-12-21 |
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