JP2018200223A - Automatic analysis device - Google Patents

Abstract

To provide an automatic analysis device that can shorten an inspection time.SOLUTION: An automatic analysis device comprises: a classification unit that, when there are two or more samples having specific items set in a plurality of samples targeted for inspection, and one more samples having general inspection items set therein, classifies the plurality of samples into a first group consisting of at least a first and second sets, of two or more sets making one pair of one specific item and one sample having the inspection item set, and a second group consisting of at least a third set making one pair of one general inspection item and one sample having the inspection item set; and an analysis control unit that allocates each set of the first and second group to each reaction container. The analysis control unit is configured to: cause a reagent of the inspection item of the set of any one group of the first or the second group to dispense; and, after the dispersion of the reagent of all inspection items of the set of one group, cause a reagent of the inspection item of the set of other group to disperse.SELECTED DRAWING: Figure 7

Description

  Embodiments described herein relate generally to an automatic analyzer that dispenses a sample and a reagent collected from a subject into a reaction container and analyzes components contained in the sample.

  The automatic analyzer is intended for biochemical test items, immunological test items, etc., and samples collected from the subject and reagents used for the analysis of each test item are dispensed into reaction containers. Changes in color tone and turbidity caused by the reaction of the reagent are optically measured. The automatic analyzer can obtain analysis data represented by the concentration of each test item component contained in the sample, the activity of the enzyme, and the like based on the measurement result.

  The automatic analyzer consists of multiple reaction vessels, a sample dispensing probe that dispenses a sample into a reaction vessel stopped at the sample dispensing position, and a reagent dispensing that dispenses a reagent into the reaction vessel stopped at the reagent dispensing position. In the inspection, based on the order set in advance for each sample, the dispensing of the sample for all the inspection items set in the early order sample is completed, and then the next sample in the early order The sample for the inspection item set in the sample in the order of is dispensed.

  The sample dispensing position includes the first or second sample dispensing position, and the sample dispensing probe dispenses the sample into the reaction container stopped at the first or second sample dispensing position. Each reaction vessel stops in the order of the first sample dispensing position, the reagent dispensing position, and the second sample dispensing position. In the case of sample and reagent dispensing for general inspection items in which the sample dispensing amount exceeds a preset upper limit amount, the sample dispensing probe is placed in the upper limit amount in the reaction container stopped at the first sample dispensing position. The reagent dispensing probe dispenses the reagent into the reaction container stopped at the reagent dispensing position. In addition, in the dispensing of samples and reagents for specific inspection items whose sample dispensing amount is less than or equal to the upper limit amount, the sample dispensing probe dispenses the reagent at the reagent dispensing position and moves it to the second sample dispensing position. Dispense less than the maximum amount of sample into the stopped reaction vessel.

  Therefore, in the sample dispensing probe, the next sample in which the sample for a specific inspection item set in the early sample is dispensed is the sample in the next sequence after the early sample, and the next sample is dispensed. If the sample is a sample for a general inspection item set in the sample, the first sample is dispensed until the dispensing of the sample for the specific inspection item is completed in the reaction container stopped at the second sample dispensing position. The next sample cannot be dispensed into the reaction vessel stopped at the pouring position. For this reason, an empty reaction container in which the sample and the reagent are not dispensed is generated, and there is a problem that the inspection takes time.

JP 2006-224003 A

  The problem to be solved by the present invention is to provide an automatic analyzer capable of shortening the inspection time.

  In order to achieve the above-described problem, the automatic analyzer according to the embodiment includes two or more samples in which a specific inspection item is set among a plurality of samples to be inspected, and general other than the specific inspection item If there are one or more samples set with the inspection item, at least the first of the two or more sets including one specific inspection item and one sample set with the inspection item A first group consisting of a set and a second set, and a second group consisting of at least a third set including one general inspection item and one sample in which the inspection item is set as one set The classification unit to be classified, and the reagents of all the test items of the set belonging to either one of the first group or the second group classified by the classification unit are first dispensed, and the other group Reagents for test items belonging to And a control unit for dispensed.

The block diagram which shows the structure of the automatic analyzer which concerns on embodiment. The perspective view which shows an example of a structure of the analysis part which concerns on embodiment. The figure which shows an example of each stop position which stops when the sample dispensing probe which concerns on embodiment attracts | sucks the sample in a sample container. The figure which shows an example of each stop position which stops when the sample dispensing probe which concerns on embodiment discharges a sample in the reaction container. The figure which shows an example of each stop position of each reaction container which concerns on embodiment, and the position of a measurement part and a washing nozzle. The figure which shows operation | movement of each unit of the analysis part performed at each stop position of each reaction container which concerns on embodiment. Each sample to be inspected when not classified into the first and second groups and when classified into the first and second groups according to the first specific item according to the embodiment, and set for this sample The figure which shows the order of dispensing of the reagent of each test | inspection item. The figure which shows the detail of the dispensing operation | movement of the reagent of each test | inspection sample when not classifying into the 1st and 2nd group by the 1st specific item which concerns on embodiment, and each test | inspection item set to this sample . The figure which shows the detail of the dispensing operation | movement of the reagent of each test object set to this test sample and each test item in the case of being classified into the 1st and 2nd group by the 1st specific item which concerns on embodiment . Each sample to be inspected when it is not classified into the first and second groups and when it is classified into the first and second groups according to the second specific item according to the embodiment, and set for this sample The figure which shows the order of dispensing of the reagent of each test | inspection item. The figure which shows the detail of dispensing operation | movement of the reagent of each test | inspection object set to this sample and each test | inspection item when not classified into the 1st and 2nd group by the 2nd specific item which concerns on embodiment . The figure which shows the detail of the dispensing operation | movement of the reagent of each test | inspection object set to this sample and each test | inspection item in the case of being classified into the 1st and 2nd group by the 2nd specific item which concerns on embodiment . Each sample to be inspected when it is not classified into the first and second groups and when it is classified into the first and second groups according to the third specific item according to the embodiment, and set for this sample The figure which shows the order of dispensing of the reagent of each test | inspection item. The figure which shows the detail of the dispensing operation | movement of the reagent of each test | inspection sample when not classifying into the 1st and 2nd group by the 3rd specific item which concerns on embodiment, and each test | inspection item set to this sample . The figure which shows the detail of the dispensing operation | movement of the reagent of each test item set to this sample and each test item in the case of being classified into the 1st and 2nd group by the 3rd specific item which concerns on embodiment . Each sample to be inspected when it is not classified into the first and second groups and when it is classified into the first and second groups according to the fourth specific item according to the embodiment, and set for this sample The figure which shows the order of dispensing of the reagent of each test | inspection item. The figure which shows the position of each reaction container which allocated each sample and each test | inspection item when not classified into the 1st and 2nd group by the 4th specific item which concerns on embodiment. The figure which shows the detail of the dispensing operation | movement of the reagent of each test item set to this sample and each test item when not classified into the 1st and 2nd group by the 4th specific item which concerns on embodiment . The figure which shows the position of each reaction container which allocated each sample and each test | inspection item in the case of being classified into the 1st and 2nd group by the 4th specific item which concerns on embodiment. The figure which shows the detail of the dispensing operation | movement of the reagent of each test item set to this sample and each test | inspection object in the case of being classified into the 1st and 2nd group by the 4th specific item which concerns on embodiment .

  Hereinafter, embodiments will be described with reference to the drawings.

  FIG. 1 is a block diagram illustrating a configuration of an automatic analyzer according to the embodiment. This automatic analyzer 100 dispenses a standard sample corresponding to each inspection item, a sample such as a test sample, and a reagent corresponding to each inspection item, and measures each sample and a mixed solution of each reagent to measure the standard. An analysis unit 10 that generates data and test data is provided. The automatic analyzer 100 further includes a drive unit 50 that drives a plurality of units that perform dispensing of each sample of the analyzing unit 10 and dispensing of reagents for each inspection item.

  In addition, the automatic analyzer 100 controls the driving unit 50 and the classification unit 51 that classifies a plurality of sets into two groups with each sample to be inspected and one inspection item set for the sample as one set. And an analysis control unit 52. The automatic analyzer 100 further includes a data processing unit 60 that processes the standard data and test data generated by the analysis unit 10 to generate calibration data and analysis data for each inspection item. The automatic analyzer 100 further includes a display unit 70 that displays calibration data, analysis data, and the like generated by the data processing unit 60.

  In addition, the automatic analyzer 100 inputs for setting analysis parameters such as sample and reagent dispensing amounts necessary for measurement of the inspection item for each inspection item, sample ID and inspection for each sample to be inspected. An input unit 80 is provided for performing input for setting each target inspection item, input for executing inspection, and the like. The automatic analyzer 100 further includes a system control unit 90 that controls the classification unit 51, the analysis control unit 52, the data processing unit 60, and the display unit 70 in an integrated manner.

  FIG. 2 is a perspective view illustrating an example of the configuration of the analysis unit 10. The analysis unit 10 includes a sample container 11 that stores each sample such as a standard sample and a test sample, and a sample table 12 that holds a plurality of sample containers 11 so as to be movable. In addition, the analysis unit 10 is a reagent that reacts with the components of each test item included in each sample, for example, one reagent system composed of the first reagent, two reagent systems composed of the first and second reagents, and first to third. A first reagent container 13 containing a first reagent of a three-reagent system composed of reagents, a diluent for diluting a sample, a third reagent and a cleaning liquid, and a plurality of first reagent containers 13 movably held. 1 reagent rack 14.

  In addition, the analysis unit 10 can move the second reagent container 15 containing each of the second reagent and the cleaning liquid paired with the first reagent of the two reagent system and the third reagent system, and the plurality of second reagent containers 15. And a second reagent rack 16 to be held. The analysis unit 10 includes a plurality of reaction vessels 17 arranged on the circumference, and a reaction table 18 that holds the reaction vessels 17 so as to be rotatable.

  In addition, the analysis unit 10 sucks the sample in each sample container 11 held on the sample table 12 and disposes the sample dispensing probe 19 for dispensing into the reaction container 17 and the sample dispensing probe 19. A sample dispensing arm 20 that is supported so as to be vertically movable and rotatable is provided. The analysis unit 10 also includes a sample liquid level sensor 21 that detects that the sample dispensing probe 19 has come into contact with the liquid level of the sample in each sample container 11, and a sample cleaning tank 22 that cleans the sample dispensing probe 19. And.

  The sample liquid level sensor 21 includes, for example, an oscillator, a bridge circuit, and the like. The change in the capacitance of the sample dispensing probe 19 when it comes into contact with the sample in each sample container 11 is converted into a voltage signal by the bridge circuit. The liquid level of the sample is detected.

  In addition, the analysis unit 10 aspirates the first reagent, the third reagent, and the diluted liquid in each first reagent container 13 held in the first reagent rack 14 and discharges them into the reaction container 17. A first reagent dispensing probe 23 is provided. The analysis unit 10 also includes a first reagent dispensing arm 24 that supports the first reagent dispensing probe 23 so as to be vertically movable and rotatable. The analysis unit 10 also includes a first reagent cleaning tank 25 that cleans the first reagent dispensing probe 23.

  In addition, the 1st reagent dispensing probe 23 adhered at the time of dispensing using washing water in the 1st reagent washing tank 25 for every dispensing of the 1st reagent of each 1st reagent container 13, or the 3rd reagent. Washing is performed to wash off the first reagent or the third reagent. In addition, the first reagent dispensing probe 23 performs a stronger cleaning than the cleaning using the cleaning water by sucking the cleaning liquid in the first reagent container 13 and discharging it to the first reagent cleaning tank 25, thereby After discharging the cleaning liquid in the reagent cleaning tank 25, cleaning is performed using the cleaning water to wash off the attached cleaning liquid.

  The analysis unit 10 also includes a first stirrer 26 that stirs and mixes the sample and the first reagent, the sample and the diluent, or the sample and the first to third reagents in the reaction container 17, and the first stirrer 26. And a first agitation arm 27 that movably supports the first agitation arm 27. The analysis unit 10 further includes a second stirrer 28 that stirs and mixes the sample and the first reagent in the reaction container 17 and a second stirrer arm 29 that movably supports the second stirrer 28. Yes.

  In addition, the analysis unit 10 sucks the second reagent in each second reagent container 15 held in the second reagent rack 16 and dispenses the first reagent paired with the second reagent. A second reagent dispensing probe 30 that performs dispensing to be discharged into the chamber 17 is provided. The analysis unit 10 also includes a second reagent dispensing arm 31 that supports the second reagent dispensing probe 30 so as to be movable up and down and rotatable. The analysis unit 10 also includes a second reagent cleaning tank 32 that cleans the second reagent dispensing probe 30.

  The second reagent dispensing probe 30 uses the washing water in the first reagent washing tank 25 for each dispensing of the second reagent in each second reagent container 15 to remove the second reagent attached at the time of dispensing. Washing off is performed. In addition, the second reagent dispensing probe 30 performs a stronger washing than the washing using the washing water by sucking the washing liquid of the second reagent container 15 and discharging it to the second reagent washing tank 32, so that the second reagent dispensing probe 30 After discharging the cleaning liquid in the reagent cleaning tank 32, cleaning is performed using the cleaning water to wash off the attached cleaning liquid.

  The analysis unit 10 also includes a third stirrer 33 that stirs and mixes the sample in the reaction vessel 17, the first reagent, and the second reagent, and a third stirrer arm that movably supports the third stirrer 33. 34. Further, the analysis unit 10 irradiates the reaction container 17 with light, and detects light transmitted through the mixed liquid in which the standard sample or the test sample and the reagent in the reaction container 17 are mixed, thereby standard data or test data. The measurement part 35 which produces | generates is provided. The analysis unit 10 also cleans the reaction container 17 that is dispensed by the sample dispensing probe 19 and the reaction container 17 that has been measured, and a cleaning nozzle 36 that supports the cleaning nozzle 36 so as to be movable up and down. Arm 37.

  Returning to FIG. 1, the drive unit 50 includes a motor that rotationally drives the sample table 12, and moves the sample container 11. The drive unit 50 includes motors that rotate the first and second reagent racks 14 and 16, respectively, and move the first and second reagent containers 13 and 15. The drive unit 50 has a motor that rotationally drives the reaction table 18 and moves each reaction vessel 17.

  The drive unit 50 includes a motor for driving and rotating the sample dispensing arm 20, the first reagent dispensing arm 24, and the second reagent dispensing arm 31, respectively, and a motor for vertically driving the sample dispensing arm 19, The first reagent dispensing probe 23 and the second reagent dispensing probe 30 are moved. The drive unit 50 has motors that drive the first to third stirring arms 27, 29, and 34, respectively, and moves the first to third stirring bars 26, 28, and 33. The drive unit 50 has a motor that drives the cleaning arm 37 up and down, and moves the cleaning nozzle 36.

  The classification unit 51 is set to the CPU and the information of a specific inspection item (specific item) set in advance, the sample ID for identifying each sample to be inspected input from the input unit 80, and the sample of this sample ID. A storage circuit for storing information on each inspection item is included. The classification unit 51 includes two or more samples in which specific items are set among a plurality of samples to be inspected, and samples in which general inspection items (general items) other than the specific items are set. If there are one or more, a first group consisting of at least a first group and a second group including one specific item and one sample in which this inspection item is set, one general item, and this inspection The sample is classified into at least a second group consisting of at least a third group, with one sample set as an item.

  There are four types of first to fourth specific items. In the first specific item, a threshold value and a retest condition for the diluent are set as analysis parameters, and when the analysis data when the first test is performed exceeds the threshold value, the second test is performed. It is an inspection item. In the second inspection, the sample and the diluted solution are dispensed into the reaction vessel 17, a diluted sample is prepared by diluting the sample with the diluent in the reaction vessel 17, and the diluted sample and the reagent in the reaction vessel 17 are added to the reaction vessel. 17 is dispensed into a separate reaction vessel 17.

  In addition, the first specific item is that the sample container 11 that contains a sample composed of an upper layer sample containing serum and a lower layer sample containing blood cells separated into lower layers, for example, blood separated by a centrifuge and separated into upper layers. This is an inspection item in which the lower layer sample and the diluted solution are dispensed into the reaction vessel 17 and the diluted sample and reagent prepared in the reaction vessel 17 are dispensed into the reaction vessel 17 and another reaction vessel 17 for inspection. .

  The second specific item is an inspection item that requires dispensing of a small amount of sample in which the amount of sample dispensed into the reaction container 17 is equal to or less than a predetermined amount.

  The third specific item is an inspection item that affects the inspection item that is set in advance and the inspection item that is affected by the inspection item. The classification unit 51 sets the test item to be affected and the test item to be affected by the test item, and dispenses the reagent of the test item to be affected next to the dispensing of the reagent of the test item to be affected. If there are two samples set with the test item that affects and the test item that is affected, the first group of the first and second sets and the test item that is affected are the general test items. Are classified into a second group consisting of a third group and a fourth group, each including one general item and one sample in which the inspection item is set.

  Here, the test item to be affected and the test item to be affected are, for example, the first reagent of the test item that is affected by the dispensing of the first reagent following the dispensing of the first reagent. In some cases, this refers to a test item in which the analysis data of the test item affected by the carry-over of the first reagent from the first reagent dispensing probe 23 becomes abnormal. If the test item that is affected by the input from the input unit 80 and the test item that is affected are set in advance, the analysis control unit 52 performs dispensing of the first reagent of the test item that affects the test item, for example. First, the first reagent dispensing probe 23 sucks the cleaning solution of the first reagent container 13 and causes the first reagent cleaning tank 25 to discharge the cleaning solution, and then dispenses the first reagent of the affected test item. Let it be done.

  The fourth specific item is a three-reagent system inspection item including the first to third reagents.

  The analysis control unit 52 includes a CPU and a storage circuit. The analysis parameters of each inspection item input from the input unit 80, the sample ID of each sample to be inspected, and each inspection set for the sample identified by this sample ID. Based on the input information of the items, each reaction container 17 of the analysis unit 10 is moved, each reaction container 17 is washed, each sample container 11 is moved, each first reagent container 13 is moved, and each second reagent container 15 is moved. The drive unit 50 is caused to perform analysis operations such as dispensing of each sample, dispensing of reagents for each test item, stirring of the sample and reagents for each test item set in the sample.

  The analysis control unit 52 belongs to one of the first group and the second group classified by the classification unit 51 for each reaction container 17 that is cleaned by the cleaning nozzle 36 of the analysis unit 10. A group is preferentially allocated, and then a group belonging to the other group is allocated. Then, the analysis control unit 52 causes the reaction container 17 to which the group belonging to one group is assigned to first dispense the reagents of all the test items of the group belonging to one group, and assigns the group belonging to the other group. The reaction container 17 is made to dispense the reagent of the test item belonging to the other group later.

  Moreover, the analysis control part 52 is based on the order set in advance for the plurality of samples to be inspected when the number of samples to which the specific item is set is one or less among the plurality of samples to be inspected. After the dispensing of the sample for all the inspection items set in the sample is completed, the sample for the inspection item set in the sample in the order next to the sample in the early order is dispensed.

  The analysis control unit 52 sucks the upper layer sample in the sample container 11 and dispenses the sample for one item when dispensing the sample when the first specific item is an inspection item for the second inspection. In the dispensing, the lower layer sample of the sample separated into the upper layer and the lower layer in the sample container 11 is sucked.

  In the suction of the upper layer sample, the sample dispensing probe 19 descends from above the sample container 11 for storing a sample composed of one layer such as serum or urine or the sample container 11 for storing a sample separated from the whole blood into upper and lower layers. 3A, after the lower end of the sample dispensing probe 19 comes into contact with the liquid level of the upper layer sample in the sample container 11 and stops at the position detected by the sample liquid level sensor 21, The upper layer sample in the sample container 11 is sucked.

  In the suction of the lower layer sample, the sample dispensing probe 19 descends from above the sample container 11 containing the sample separated into the upper layer and the lower layer, and as shown in FIG. 3B, the lower end of the sample dispensing probe 19 Stops at a position near the bottom surface in the sample container 11, and then a lower layer sample such as blood cells is sucked.

  In addition, as shown in FIG. 4A, the analysis control unit 52 performs dispensing of samples for inspection items other than the second specific item in which a dispensing amount exceeding a predetermined amount is set as an analysis parameter. The sample dispensing probe 19 is stopped at a position where the lower end comes into contact with the bottom surface of the reaction container 17 that has been cleaned by the cleaning nozzle 36 and is emptied, and then a sample exceeding a predetermined amount is discharged.

  In addition, in the dispensing of the sample for the second specific item in which a minute dispensing amount of a predetermined amount or less is set as the analysis parameter, the analysis control unit 52 performs cleaning as shown in FIG. After washing by the nozzle 36, the sample is dispensed at a position where the lower end is in contact with the liquid level of the first reagent in the reaction container 17 containing the dispensed first reagent and detected by the sample liquid level sensor 21. After the probe 19 is stopped, a sample of a predetermined amount or less is discharged.

  As described above, when the sample is discharged from the position where the lower end of the sample dispensing probe 19 is in contact with the first reagent, the sample discharged from the sample dispensing probe 19 is scattered or the sample dispensing probe of the discharged sample is scattered. 19 Adhesion to the outer wall of the lower end can be prevented. Thereby, a very small amount of sample can be dispensed with high accuracy.

  In addition, although there are two or more samples set with specific items and one or more samples set with general items among a plurality of samples to be inspected, the first and second samples If it is not classified into groups, the analysis control unit 52 dispenses the samples for all the inspection items set to the samples in the earlier order based on the order set in advance for the plurality of samples to be inspected. After completion, the sample for the inspection item set in the sample in the next order of the sample in the early order is dispensed.

  The data processing unit 60 includes, for example, a CPU and a storage circuit, and generates standard data generated by the measurement unit 35 of the analysis unit 10 and calibration data indicating a relationship between standard values set in advance in standard samples of the standard data. . The data processing unit 60 uses the generated calibration data to generate analysis data represented by concentration values and enzyme activity values from the test data generated by the test. The data processing unit 60 has a storage such as a hard disk drive (HDD), stores the generated calibration data for each test item, and stores the generated analysis data for each test item for each test sample.

  The display unit 70 has a monitor such as a CRT or a liquid crystal panel, for example, and displays calibration data and analysis data generated by the data processing unit 60. Further, the display unit 70 displays a screen for setting analysis parameters such as a sample dispensing amount, a first reagent dispensing amount, and a second reagent dispensing amount for each inspection item. The display unit 70 displays a screen for setting a sample ID for identifying the test sample and each inspection item to be tested for each test sample.

  The input unit 80 includes input devices such as a keyboard, a mouse, a button, and a touch panel. The input unit 80 inputs to set analysis parameters for each inspection item, inputs to set the sample ID and each inspection item of each sample to be inspected, and the first and second reagent racks 14 and 16. An input for setting the holding position of the first and second reagent containers 13 and 15 of each inspection item to be held is performed. In addition, the input unit 80 performs input for causing the analysis unit 10 to execute calibration and inspection.

  The system control unit 90 includes a CPU and a storage circuit. The command signal input from the input unit 80, the analysis parameter of each inspection item, the sample ID and the inspection item, and the holding positions of the first and second reagent containers 13 and 15 Are stored in the storage circuit, and based on the input information, the classification unit 51, the analysis control unit 52, the data processing unit 60, the display unit 70, and the like are integrated to control the entire system.

  Hereinafter, with reference to FIG. 1 thru | or 20, each of the test object of the case where it is not classified into the 1st and 2nd group by the classification | category part 51, and the case where it is classified into the 1st and 2nd group An example of the dispensing operation of the sample and the reagent of each inspection item set in the sample will be described.

  First, each stop position where each reaction vessel 17 stops, and the positions of the measurement unit 35 and the washing nozzle 36 will be described.

  FIG. 5 is a diagram illustrating an example of each stop position of each reaction vessel 17 and the positions of the measurement unit 35 and the washing nozzle 36.

  Each reaction container 17 is rotationally moved in one direction every cycle time by the rotation drive of the reaction table 18 by the drive unit 50, and is thus subjected to a cleaning position W, a sample discharge position Pa, a first reagent discharge position Pb, and a first stirring position. At each stop position including Pc, sample suction / discharge position Pd, second stirring position Pe, second reagent discharge position Pf, and third stirring position Pg, cleaning position W, sample discharge position Pa, first reagent discharge position Pb, The first stirring position Pc, the sample suction / discharge position Pd, the second stirring position Pe, the second reagent discharge position Pf, and the third stirring position Pg are stopped in this order, and n cycles after n (n is an integer of 1 or more) cycle time. Stops at each stop position adjacent to the stop position stopped before the time.

  In the following, each reaction vessel 17 draws a circular arc with a central angle θ every cycle time, rotates and moves in the direction of arrow R1, stops at each stop position, and stops at a stop position 4 cycles before 4 cycle times. And stop at the stop position adjacent to the arrow R2 direction opposite to the R1 direction. In addition, each reaction container 17 has a land time obtained by multiplying, for example, 165, which is the number of reaction containers 17 held in the reaction table 18, by one cycle time, and is stopped one round time before one round time after each round time. Stop at the stop position.

  The measurement unit 35 includes a light source and a detector arranged across the inner and outer circumferences of each reaction container 17, and irradiates each reaction container 17 that passes through the measurement position Pm with each rotation of the reaction table 18. Then, the light transmitted through the liquid mixture containing the standard sample and the test sample in each reaction vessel 17 is detected, and standard data and test data expressed by absorbance are generated.

  The cleaning nozzle 36 includes first to seventh cleaning nozzles 41 to 47 supported by the same cleaning arm 37. The cleaning position W is configured by first to seventh cleaning positions W1 to W7 where the seven adjacent reaction vessels 17 are stopped. The first cleaning nozzle 41 performs cleaning by sucking the mixed liquid in the reaction container 17 that contains the mixed liquid whose measurement has been completed among the reaction containers 17 stopped at the first cleaning position W1. In addition, the second cleaning nozzle 42 cleans the reaction container 17 that has been cleaned at the first cleaning position W1 among the reaction containers 17 stopped at the second cleaning position W2 by, for example, discharging and sucking an alkaline cleaning liquid. I do. The third cleaning nozzle 43 cleans the reaction container 17 that has been cleaned at the second cleaning position W2 among the reaction containers 17 stopped at the third cleaning position W3 by, for example, discharging and sucking an acid cleaning liquid. I do. The fourth cleaning nozzle 44 cleans the reaction container 17 that has been cleaned at the third cleaning position W3 among the reaction containers 17 stopped at the fourth cleaning position W4, for example, by discharging and sucking cleaning water. I do. The fifth cleaning nozzle 45 cleans the reaction container 17 that has been cleaned at the fourth cleaning position W3 among the reaction containers 17 stopped at the fifth cleaning position W5 by, for example, discharging and sucking cleaning water. I do. The sixth cleaning nozzle 46 performs cleaning by sucking the cleaning water in the reaction container 17 cleaned at the fifth cleaning position W5 among the reaction containers 17 stopped at the sixth cleaning position W6. The seventh cleaning nozzle 47 is emptied by further suction of the cleaning water in the reaction container 17 cleaned at the sixth cleaning position W6 among the reaction containers 17 stopped at the seventh cleaning position W7. Wash.

  FIG. 6 is a diagram illustrating the operation of each unit of the analysis unit 10 performed at each stop position of each reaction vessel 17.

  The analysis control unit 52 assigns each sample to be inspected or each inspection item set for this sample to the reaction vessel 17 that dispenses a diluted sample obtained by diluting the sample with a diluent.

  The cleaning nozzle 36 of the analysis unit 10 cleans the reaction container 17 in which the sample or the diluted sample is dispensed among the reaction containers 17 stopped at the cleaning position W, and the reaction container 17 that stores the mixed liquid that has been measured. .

  The reaction container 17 at the seventh cleaning position W7 which has been emptied after the cleaning is stopped at the sample discharge position Pa, for example, as a first cycle after a cycle of two cycle times since stopping at the seventh cleaning position W7.

  In the first cycle, the sample dispensing probe 19 moves the sample table 12 to the reaction container 17 to which inspection items other than the sample and the second specific item are assigned out of the empty reaction containers 17 stopped at the sample discharge position Pa. The sample in the sample container 11 held in is dispensed.

  In the second cycle after one cycle time has elapsed from the first cycle, the reaction container 17 stopped at the sample discharge position Pa in the first cycle stops at the first reagent discharge position Pb. The first reagent dispensing probe 23 is placed in the first reagent rack 14 in the reaction container 17 to which inspection items other than the sample and the first specific item are assigned out of the reaction containers 17 stopped at the first reagent discharge position Pb. The first reagent of the inspection item in the held first reagent container 13 is dispensed. The first reagent dispensing probe 23 is held in the first reagent rack 14 in the reaction container 17 to which the sample and the first specific item are assigned among the reaction containers 17 stopped at the first reagent discharge position Pb. The diluted solution in the first reagent container 13 or the first reagent of the first specific item is dispensed.

  In the 4th cycle, in which 2 cycle times have elapsed from the 2nd cycle, the reaction vessel 17 stopped at the first reagent discharge position Pb in the 2nd cycle stops at the first stirring position Pc. The first stirrer 26 agitates and mixes the sample and the first reagent in the reaction container 17 into which the sample and the first reagent are dispensed among the reaction containers 17 stopped at the first stirring position Pc. Moreover, the 1st stirring element 26 stirs and mixes the sample and dilution liquid in the reaction container 17 into which the sample and dilution liquid were dispensed among the reaction containers 17 stopped to the 1st stirring position Pc.

  In the fifth cycle when one cycle time has elapsed from the fourth cycle, the reaction vessel 17 stopped at the first stirring position Pc in the fourth cycle stops at the sample suction / discharge position Pd adjacent to the sample discharge position Pa in the R2 direction. . The sample dispensing probe 19 sucks the diluted sample in the reaction container 17 containing the diluted sample mixed with the sample and the diluent by the first stirrer 26 among the reaction containers 17 stopped at the sample suction / discharge position Pd. Then, dispensing is performed to the empty reaction container 17 that is assigned to the sample and the first specific item and stopped at the sample discharge position Pa. The sample dispensing probe 19 is assigned with the sample and the second specific item among the reaction vessels 17 stopped at the sample suction / discharge position Pd, and contains the first reagent of the second specific item. The sample in the sample container 11 held on the sample table 12 is dispensed.

  Thus, by arranging the sample suction / discharge position Pd next to the sample discharge position Pa, the reaction container at the sample discharge position Pa of the diluted sample in the reaction container 17 at the sample suction / discharge position Pd by the sample dispensing probe 19. 17 and the sample in the sample container 11 held on the sample table 12 can be dispensed into the reaction container 17 at the sample suction / discharge position Pd.

  In the sixth cycle after one cycle time has elapsed from the fifth cycle, the reaction vessel 17 stopped at the sample suction / discharge position Pd in the fifth cycle stops at the second stirring position Pe. The second stirrer 28 is a reaction container in which the diluent is dispensed at the first reagent discharge position Pb after the sample is dispensed at the sample discharge position Pa among the reaction containers 17 stopped at the second stirring position Pe. Stir and mix the sample and diluent in 17. In addition, the second stirring bar 28 sucks / discharges the sample after the first reagent of the second specific item is dispensed at the first reagent discharge position Pb in the reaction container 17 stopped at the second stirring position Pe. The first reagent and the sample in the reaction container 17 into which the sample has been dispensed at the position Pd are agitated and mixed.

  In the d-th cycle after a predetermined cycle time has elapsed from the sixth cycle, the reaction vessel 17 stopped at the second stirring position Pe in the sixth cycle stops at the second reagent discharge position Pf. Among the reaction containers 17 stopped at the second reagent discharge position Pf, the second reagent dispensing probe 30 is attached to the reaction container 17 in which the sample and the first reagent of the 2-reagent system or 3-reagent system test item are dispensed. The second reagent of the inspection item in the second reagent container 15 held in the second reagent rack 16 is dispensed.

  In the (d + 1) cycle when one cycle time has elapsed from the d cycle, the reaction vessel 17 stopped at the second reagent discharge position Pf in the d cycle stops at the third stirring position Pg. The third stirring bar 33 removes the sample, the first reagent, and the second reagent in the reaction container 17 into which the sample, the first reagent, and the second reagent are dispensed among the reaction containers 17 stopped at the third stirring position Pg. Stir and mix.

  The measurement unit 35 is a reaction container that passes through the measurement position Pm after the sample and the first reagent of the inspection item of the one reagent system are stirred at the first stirring position Pc in the fourth cycle until it stops at the cleaning position W. The mixed liquid in 17 is measured and test data is generated. In addition, the measurement unit 35 passes through the measurement position Pm after the sample and the first reagent of the inspection item of the one reagent system are stirred at the second stirring position Pe in the sixth cycle until it stops at the cleaning position W. Test liquid is generated by measuring the liquid mixture in the reaction vessel 17.

  In addition, the measurement unit 35 waits for the (d + 1) cycle to stir at the washing position W after the sample and the first and second reagents of the two-reagent system or the three-reagent system test item are stirred at the third stirring position Pg. During this time, the liquid mixture in the reaction vessel 17 passing through the measurement position Pm is measured, and test data is generated by measuring the sample and the liquid mixture of the first and second reagents in the two-reagent system test item.

  The reaction vessel 17 stopped at the third stirring position Pg in the (d + 1) cycle is the g cycle, (g + 4) cycle, (g + 8) cycle, (g + 12) cycle, (g + 16) cycle, (g + 20) In each cycle of the cycle and (g + 24) cycle, it stops at each of the first to seventh cleaning positions W7.

  Each of the first to seventh cleaning nozzles 41 to 47 descends when the reaction container 17 other than the reaction container 17 to which the three-reagent inspection item is assigned stops at each of the first to seventh cleaning positions W7. The seven reaction vessels 17 at each of the first to seventh cleaning positions W7 are cleaned. Further, each of the first to seventh cleaning nozzles 41 to 47 does not descend when the reaction container 17 to which the inspection item of the three reagent system is assigned stops at each of the first to seventh cleaning positions W7. The cleaning of the seven reaction vessels 17 at the seventh cleaning position W7 is stopped.

  Hereinafter, only the reaction container 17 into which the sample and the first and second reagents of the three-reagent test items are dispensed will be described.

  At the (g + 27) cycle time when 3 cycle times have elapsed from the (g + 24) cycle, the reaction vessel 17 stopped at the seventh cleaning position W7 at the (g + 24) cycle stops at the first reagent discharge position Pb. The first reagent dispensing probe 23 is placed in the reaction container 17 containing the sample stopped at the first reagent discharge position Pb and the first and second reagents of the three-reagent system test items. Dispense the third reagent.

  In the (g + 29) cycle when two cycle times have elapsed from the (g + 27) cycle time, the reaction vessel 17 stopped at the first reagent discharge position Pb in the (g + 27) cycle stops at the first stirring position Pc. The first stirrer 26 stirs and mixes the sample in the reaction vessel 17 stopped at the first stirring position Pc and the first to third reagents.

  The measuring unit 35 measures from the time when the sample and the sample of the test item of the three reagent system and the first to third reagents are stirred at the first stirring position Pc to the stop at the cleaning position W in the (g + 29) cycle. Test liquid is generated by measuring the liquid mixture in the reaction vessel 17 passing through the position Pm.

  Each of the washing nozzles 36 was not washed when it stopped at each washing position W during the g cycle to the (g + 24) cycle. When one round time has elapsed after stopping at the cleaning position W, cleaning is performed when the cleaning position W stops.

  Next, referring to FIG. 7 to FIG. 9, there are a plurality of samples to be inspected that have two or more samples set with the first specific item and one or more samples set with the general item. The inspection items set for this sample are the objects to be inspected when they are not classified into the first and second groups by the first specific item and when they are classified into the first and second groups. An example of the dispensing operation of each sample and the reagent of each inspection item set in this sample will be described.

  FIG. 7 shows each sample to be inspected when it is not classified into the first and second groups according to the first specific item and when it is classified into the first and second groups, and is set for this sample. It is the figure which showed the order of dispensing of the reagent of each test | inspection item.

  For example, two inspection items A and B are set in each of the two samples S1 and S2 to be inspected. The inspection item A is, for example, a first specific item of a two reagent system, and the inspection item B is a general item of a two reagent system. In such a case, since the first specific item and the general item are set in the two samples S1 and S2, the classification unit 51 sets the sample S1 and the inspection item A as the first set, and the sample S2 and the inspection item. A first group consisting of two sets with A as the second set, a second set consisting of two sets with the sample S1 and the inspection item B as the third set and the sample S2 and the inspection item B as the fourth set Can be classified into groups.

  If the first to fourth groups are not classified into the first and second groups and are set to dispense in the order of the sample S1 and the sample S2, for example, the analysis control unit 52 sequentially uses the cleaning nozzle 36. The first set and the third set are assigned with priority to each reaction vessel 17 to be washed, and then the second set and the fourth set are assigned. Then, the analysis control unit 52 causes each reaction container 17 assigned with the first and third sets to dispense the sample S1 for each inspection item A, B set in the sample S1, and each inspection item A, B After the dispensing of the sample S1 is completed, the sample S2 for each of the inspection items A and B set in the sample S2 is dispensed to each reaction vessel 17 to which the second and fourth groups are assigned.

  When the first to fourth groups are classified into the first and second groups, the analysis control unit 52 sets the first group and the second group for each reaction vessel 17 that is sequentially cleaned by the cleaning nozzle 36. The second set is assigned with priority, and then the third set and the fourth set are assigned. And the analysis control part 52 dispenses the 1st reagent of the test item A set to each sample S1, S2 to each reaction container 17 which allocated the 1st and 2nd group, and each sample S1, S2 is dispensed. After the dispensing of the first reagent for the set test item A is completed, the first reagent for the test item B set for each sample S1, S2 is assigned to each reaction container 17 to which the third and fourth groups are assigned. To dispense.

  FIG. 8 shows the details of each sample to be inspected when not classified into the first and second groups by the first specific item, and the reagent dispensing operation of each inspection item set in this sample. FIG.

  The sample table 12 holds, for example, two sample containers 11. Of the two sample containers 11, one sample container 11 contains a sample S 1 and the other sample container 11 contains a sample S 2. .

  The analysis control unit 52 prepares one reaction container 17 to be cleaned at the cleaning position W, and stops at the cleaning position W four cycles after the preparation reaction container 17 stops at the cleaning position W. Then, the sample S1 and the inspection item A are assigned to the two reaction containers 17 for measuring one reaction container 17 to be cleaned. Further, the sample S1 and the inspection item B are assigned to one reaction container 17 that is stopped at the cleaning position W after one cycle time after the preparation reaction container 17 stops at the cleaning position W and is cleaned.

  Here, the reaction container 17 that stops at the cleaning position W one cycle time after the reaction container 17 to which the sample S1 and the inspection item B are allocated stops at the cleaning position W is the first unallocated one that is cleaned. The reaction vessel 17 that stops at the washing position W after one cycle time after the unassigned reaction vessel 17 stops at the washing position W is the second reaction vessel that is washed but not assigned. 17

  In addition, the analysis control unit 52 stops the cleaning reaction at the cleaning position W one cycle after the measurement reaction container 17 to which the sample S1 and the inspection item A are assigned stops at the cleaning position W, and the cleaning is performed. The reaction vessel 17 is used for preparation, and one reaction vessel 17 which is stopped and washed at the washing position W 4 cycles after the preparation reaction vessel 17 stops at the washing position W is used for measurement 2. The sample S2 and the inspection item A are assigned to each reaction container 17. Further, the sample S2 and the inspection item B are assigned to one reaction container 17 that is stopped at the cleaning position W after one cycle time after the preparation reaction container 17 stops at the cleaning position W and is cleaned.

  Here, the reaction container 17 that stops at the cleaning position W after one cycle time after the reaction container 17 to which the sample S2 and the inspection item B are allocated stops at the cleaning position W is the third unassigned though the cleaning is performed. The reaction container 17 that stops at the cleaning position W after one cycle time after the unassigned reaction container 17 stops at the cleaning position W is the fourth reaction without cleaning but assigned. It becomes a container 17.

  When the sample S1 and the inspection item A are assigned, and the preparation reaction container 17 that has been emptied after the cleaning is stopped at the sample discharge position Pa, the first cycle is defined.

  In the first cycle, the sample dispensing probe 19 dispenses the sample S1 in the sample container 11 into the reaction container 17 stopped at the sample discharge position Pa as a preparation sample S1d for preparing a diluted sample for the inspection item A. Note.

  In the second cycle, the empty reaction container 17 to which the sample S1 and the inspection item B are assigned stops at the sample discharge position Pa. The reaction container 17 into which the sample S1d has been dispensed in the first cycle stops at the first reagent discharge position Pb. The sample dispensing probe 19 dispenses the sample S1 in the sample container 11 as the sample S1B for the inspection item B into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the diluted solution Di of the first reagent container 13 held in the first reagent rack 14 to the reaction container 17 stopped at the first reagent discharge position Pb.

  In the third cycle, the unassigned first reaction container 17 stops at the sample discharge position Pa. The reaction container 17 into which the sample S1B has been dispensed in the second cycle stops at the first reagent discharge position Pb. The first reagent dispensing probe 23 dispenses the first reagent R1B of the inspection item B of the first reagent container 13 held in the first reagent rack 14 to the reaction container 17 stopped at the first reagent discharge position Pb. .

  Here, since the unassigned first reaction vessel 17 is not used until the next cleaning is performed, the description after the fourth cycle is omitted.

  In the fourth cycle, the unassigned second reaction container 17 stops at the sample discharge position Pa. The reaction container 17 into which the sample S1d and the diluent Di have been dispensed stops at the first stirring position Pc. The first stirrer 26 stirs the sample S1d and the diluent Di in the reaction vessel 17 stopped at the first stirring position Pc. By this stirring, in the reaction vessel 17 at the first stirring position Pc, the sample S1d is diluted with the diluent Di to become the diluted sample DS1.

  Here, since the unassigned second reaction vessel 17 is not used until the next cleaning is performed, the description after the fifth cycle is omitted.

  In the fifth cycle, the empty measurement reaction container 17 to which the sample S1 and the inspection item A are assigned stops at the sample discharge position Pa. The reaction container 17 into which the first reagent R1B has been dispensed in the third cycle stops at the first stirring position Pc. The reaction container 17 that stores the diluted sample DS1 stops at the sample suction / discharge position Pd. The sample dispensing probe 19 dispenses the diluted sample DS1 in the reaction container 17 stopped at the sample suction / discharge position Pd into the reaction container 17 stopped at the sample discharge position Pa. The first stirrer 26 stirs the sample S1B and the first reagent R1B in the reaction vessel 17 stopped at the first stirring position Pc.

  The dispensing of the sample S1 is completed by dispensing the diluted sample DS1 into the reaction vessel 17 stopped at the sample discharge position Pa in the fifth cycle.

  In addition, since the reaction container 17 in which the diluted sample DS1 is sucked by the sample dispensing probe 19 in the fifth cycle is used until it stops at the cleaning position W, the description after the sixth cycle is omitted.

  In the sixth cycle, the empty preparation reaction container 17 to which the sample S2 and the inspection item A are assigned stops at the sample discharge position Pa. The reaction container 17 into which the diluted sample DS1 has been dispensed in the fifth cycle stops at the first reagent discharge position Pb. The sample dispensing probe 19 dispenses the sample S2 of the sample container 11 held on the sample table 12 as the sample S2d for preparation of the inspection item A into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1A of the inspection item A of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  In the seventh cycle, the empty reaction container 17 to which the sample S2 and the inspection item B are assigned stops at the sample discharge position Pa. The reaction container 17 into which the sample S2d has been dispensed in the sixth cycle stops at the first reagent discharge position Pb. The sample dispensing probe 19 dispenses the sample S2 in the sample container 11 as the sample S2B for the inspection item B into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the diluted solution Di of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  In the eighth cycle, the unassigned third reaction container 17 stops at the sample discharge position Pa. The reaction container 17 into which the sample S2B has been dispensed in the seventh cycle stops at the first reagent discharge position Pb. The reaction container 17 into which the sample DS1 and the first reagent R1A have been dispensed stops at the first stirring position Pc. The first reagent dispensing probe 23 dispenses the second reagent R1B into the reaction container 17 stopped at the first reagent discharge position Pb. The first stirrer 26 stirs the sample DS1 and the first reagent R1A in the reaction vessel 17 stopped at the first stirring position Pc.

  Here, the third reaction vessel 17 that is not assigned is not used until it is stopped at the washing position W and washing is performed, and therefore the description after the ninth cycle is omitted.

  In the ninth cycle, the unassigned fourth reaction vessel 17 stops at the sample discharge position Pa. The reaction container 17 into which the sample S2d and the diluent Di have been dispensed stops at the first stirring position Pc. The first stirrer 26 stirs the sample S2d and the diluent Di in the reaction vessel 17 stopped at the first stirring position Pc. By this stirring, in the reaction vessel 17 at the first stirring position Pc, the sample S2d is diluted with the diluent Di to become the diluted sample DS2.

  Here, the fourth reaction vessel 17 that is not assigned is not used until it is stopped at the washing position W and washing is performed, and therefore the description after the tenth cycle is omitted.

  In the tenth cycle, the empty measurement reaction container 17 to which the sample S2 and the inspection item A are assigned stops at the sample discharge position Pa. The reaction vessel 17 into which the sample S2B and the first reagent R1B have been dispensed stops at the first stirring position Pc. The reaction container 17 that stores the diluted sample DS2 stops at the sample suction / discharge position Pd. The first stirrer 26 stirs the sample S2B and the first reagent R1B in the reaction vessel 17 stopped at the first stirring position Pc. The sample dispensing probe 19 dispenses the diluted sample DS2 in the reaction container 17 stopped at the sample suction / discharge position Pd into the reaction container 17 stopped at the sample discharge position Pa.

  With the dispensing of the diluted sample DS2 into the reaction container 17 stopped at the sample discharge position Pa in the 10th cycle, the dispensing of the sample S2 is completed, and the dispensing of all the samples S1 and S2 to be inspected is completed.

  The first reagent dispensing probe 23 dispenses the first reagent R1A to the reaction container 17 that stops at the first reagent discharge position Pb in the eleventh cycle after the diluted sample DS2 is dispensed in the tenth cycle.

  By dispensing the first reagent R1A into the reaction container 17 stopped at the first reagent discharge position Pb in the eleventh cycle, the first of all the inspection items A and B set in all the samples S1 and S2 to be inspected. The dispensing of one reagent is completed.

  The first stirrer 26 agitates the diluted sample DS2 and the first reagent R1A in the reaction vessel 17 stopped at the first agitating position Pc after the diluted sample DS2 and the first reagent R1A are dispensed.

  The second reagent dispensing probe 30 dispenses the second reagent of the test item B into the reaction container 17 that stops at the second reagent discharge position Pf after the sample S1B and the first reagent R1B are stirred in the fifth cycle. Then, after the sample DS1 and the first reagent R1A are stirred in the eighth cycle, the second reagent of the inspection item A is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  The second reagent dispensing probe 30 applies the second reagent of the inspection item B to the reaction container 17 that stops at the second reagent discharge position Pf after the sample S2B and the first reagent R1B are agitated in the tenth cycle. After the sample DS2 and the first reagent R1A are agitated, the second reagent of the inspection item A is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  The third stirrer 33 includes the sample S1B, the first reagent R1B, and the second reagent of the test item B in the reaction vessel 17 that stop at the third stirring position Pg after the second reagent of the test item B is dispensed. And the sample DS1, the first reagent R1A, and the second reagent of the test item A in the reaction container 17 that are stopped at the third stirring position Pg after the second reagent of the test item A is dispensed are stirred. .

  The third stirrer 33 also includes the sample S2B, the first reagent R1B, and the first of the inspection items B in the reaction container 17 that stop at the third stirring position Pg after the second reagent of the inspection item B is dispensed. The sample DS2, the first reagent R1A, and the second reagent of the test item A in the reaction vessel 17 that are stirred at the second reagent and stopped at the third stirring position Pg after the second reagent of the test item A is dispensed. Stir.

  The cleaning nozzle 36 cleans each reaction container 17 that has been measured and stopped at the cleaning position W, and when the cleaning of the reaction container 17 into which the first reagent R1A has been dispensed is completed in the 11th cycle, The cleaning operation is stopped after the cleaning of all the reaction vessels 17 into which the samples S1 and S2 and the reagents of the test items A and B have been dispensed is completed. When the cleaning operation is stopped, the analysis control unit 52 ends the analysis operation of the analysis unit 10.

  FIG. 9 shows the details of each sample to be inspected when classified into the first and second groups by the first specific item and the reagent dispensing operation for each inspection item set in this sample. FIG.

  The analysis control unit 52 prepares one reaction container 17 to be cleaned at the cleaning position W, and stops at the cleaning position W four cycles after the preparation reaction container 17 stops at the cleaning position W. Then, the sample S1 and the inspection item A are assigned to the two reaction containers 17 for measuring one reaction container 17 to be cleaned. In addition, one reaction container 17 that is stopped and cleaned at the cleaning position W one cycle after the preparation reaction container 17 to which the sample S1 and the inspection item A are assigned stops at the cleaning position W is prepared. And two reaction vessels 17 for measurement are used, one reaction vessel 17 being stopped and washed at the washing position W 4 cycles after the preparation reaction vessel 17 is stopped at the washing position W. The sample S2 and the inspection item A are assigned to it.

  Here, the reaction container 17 that stops at the cleaning position W one cycle time after the reaction container 17 to which the sample S2 and the inspection item A are allocated stops at the cleaning position W is the first unallocated one that is cleaned. The reaction vessel 17 that stops at the washing position W after one cycle time after the unassigned reaction vessel 17 stops at the washing position W is the second reaction vessel that is washed but not assigned. 17

  In addition, the analysis control unit 52 stops the cleaning reaction at the cleaning position W one cycle after the measurement reaction container 17 to which the sample S2 and the inspection item A are assigned stops at the cleaning position W. The sample S1 and the inspection item B are assigned to the reaction container 17. In addition, for one reaction container 17 that is stopped and cleaned at the cleaning position W one cycle after the reaction container 17 assigned the sample S1 and the inspection item B is stopped at the cleaning position W, the sample S2 And inspection item B are assigned.

  When the sample S1 and the inspection item A are assigned, and the preparation reaction container 17 that has been emptied after the cleaning is stopped at the sample discharge position Pa, the first cycle is defined.

  In the first cycle, the sample dispensing probe 19 dispenses the sample S1 in the sample container 11 as the sample S1d for preparation of the inspection item A into the reaction container 17 stopped at the sample discharge position Pa.

  In the second cycle, the sample S2 and the inspection item A are assigned, and the preparation reaction container 17 that has been emptied after the cleaning is stopped at the sample discharge position Pa. The reaction container 17 into which the sample S1d has been dispensed in the first cycle stops at the first reagent discharge position Pb. The sample dispensing probe 19 dispenses the sample S2 in the sample container 11 as the sample S2d for preparation into the reaction container 17 stopped at the sample discharge position Pa. Further, the first reagent dispensing probe 23 dispenses the dilute solution Di of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  In the third cycle, the unassigned first reaction container 17 stops at the sample discharge position Pa. The reaction container 17 into which the sample S2d has been dispensed in the second cycle stops at the first reagent discharge position Pb. The first reagent dispensing probe 23 dispenses the diluted solution Di of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  In the fourth cycle, the unassigned second reaction container 17 stops at the sample discharge position Pa. The reaction container 17 into which the sample S1d and the diluent Di have been dispensed stops at the first stirring position Pc. The first stirrer 26 stirs the sample S1d and the diluent Di in the reaction vessel 17 stopped at the first stirring position Pc. By this stirring, in the reaction container 17, the sample S1d is diluted with the diluent Di to become a diluted sample DS1.

  In the fifth cycle, the sample S1 and the inspection item A are assigned, and the measurement reaction container 17 that has been emptied after the cleaning is stopped at the sample discharge position Pa. The reaction container 17 into which the sample S2d and the diluent Di have been dispensed stops at the first stirring position Pc. The reaction container 17 that stores the diluted sample DS1 stops at the sample suction / discharge position Pd.

  In the fifth cycle, the sample dispensing probe 19 dispenses the diluted sample DS1 in the reaction container 17 stopped at the sample suction / discharge position Pd into the reaction container 17 stopped at the sample discharge position Pa. The first stirrer 26 stirs the sample S2d and the diluent Di in the reaction vessel 17 stopped at the first stirring position Pc. By this stirring, in the reaction vessel 17, the sample S2d is diluted with the diluent Di to become a diluted sample DS2.

  In the sixth cycle, the sample S2 and the inspection item A are assigned, and the measurement reaction container 17 that has been emptied after the cleaning is stopped at the sample discharge position Pa. The reaction container 17 into which the sample DS1 has been dispensed in the fifth cycle stops at the first reagent discharge position Pb. The reaction container 17 that stores the diluted sample DS2 stops at the sample suction / discharge position Pd.

  In the sixth cycle, the sample dispensing probe 19 dispenses the diluted sample DS2 in the reaction container 17 stopped at the sample suction / discharge position Pd into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1A of the inspection item A of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  In the seventh cycle, the sample S1 and the inspection item B are assigned, and the reaction container 17 that has been emptied after the cleaning is stopped at the sample discharge position Pa. The reaction container 17 into which the sample DS2 has been dispensed in the sixth cycle stops at the first reagent discharge position Pb. The sample dispensing probe 19 dispenses the sample S1 in the sample container 11 as the sample S1B for the inspection item B into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1A of the inspection item A of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  With the first reagent R1A dispensed to the reaction container 17 stopped at the first reagent discharge position Pb in the seventh cycle, the first reagent of each test item A classified into the first group is dispensed. finish.

  In the eighth cycle, the sample S2 and the inspection item B are assigned, and the reaction container 17 that has been emptied after the cleaning is stopped at the sample discharge position Pa. The reaction container 17 into which the sample S1B has been dispensed in the seventh cycle stops at the first reagent discharge position Pb. The reaction container 17 into which the sample DS1 and the first reagent R1A have been dispensed stops at the first stirring position Pc.

  In the eighth cycle, the sample dispensing probe 19 dispenses the sample S2 in the sample container 11 as the sample S2B for the inspection item B into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1B of the inspection item B of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb. The first stirrer 26 stirs the sample DS1 and the first reagent R1A in the reaction vessel 17 stopped at the first stirring position Pc.

  By dispensing the sample S2B into the reaction container 17 stopped at the sample discharge position Pa in the eighth cycle, dispensing of all the samples S1, S2 to be inspected is completed.

  In the ninth cycle, the reaction container 17 into which the sample S2B has been dispensed in the eighth cycle stops at the first reagent discharge position Pb. The reaction container 17 into which the sample DS2 and the first reagent R1A have been dispensed stops at the first stirring position Pc. The first reagent dispensing probe 23 dispenses the first reagent R1B of the inspection item B of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb. The first stirrer 26 stirs the sample DS2 and the first reagent R1A in the reaction vessel 17 stopped at the first stirring position Pc.

  With the dispensing of the first reagent R1B into the reaction container 17 stopped at the first reagent discharge position Pb in the ninth cycle, the dispensing of the first reagent of each set of inspection items B classified into the second group is finish.

  In the tenth cycle, the reaction container 17 into which the sample S1B and the first reagent R1B have been dispensed stops at the first stirring position Pc. The first stirrer 26 stirs the sample S1B and the first reagent R1B in the reaction vessel 17 stopped at the first stirring position Pc.

  In the eleventh cycle, the reaction container 17 into which the sample S2B and the first reagent R1B have been dispensed stops at the first stirring position Pc. The first stirrer 26 stirs the sample S2B and the first reagent R1B in the reaction vessel 17 stopped at the first stirring position Pc.

  The second reagent dispensing probe 30 dispenses the second reagent of the inspection item A into the reaction container 17 that stops at the second reagent discharge position Pf after the sample DS1 and the first reagent R1A are stirred in the eighth cycle. Then, after the sample DS2 and the first reagent R1A are stirred in the ninth cycle, the second reagent of the inspection item A is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  Further, the second reagent dispensing probe 30 applies the second reagent of the inspection item B to the reaction container 17 that stops at the second reagent discharge position Pf after the sample S1B and the first reagent R1B are stirred in the tenth cycle. After the sample S2B and the first reagent R1B are stirred in the eleventh cycle, the second reagent of the inspection item B is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  The third stirrer 33 includes the sample DS1, the first reagent R1A, and the second reagent of the test item A in the reaction container 17 that stops at the third stirring position Pg after the second reagent of the test item A is dispensed. And the sample DS2, the first reagent R1A, and the second reagent of the test item A in the reaction container 17 stopped at the third stirring position Pg after the second reagent of the test item A is dispensed are stirred. .

  The third stirrer 33 also includes the sample S1B, the first reagent R1B, and the first of the inspection items B in the reaction container 17 that stop at the third stirring position Pg after the second reagent of the inspection item B is dispensed. The sample S2B, the first reagent R1B, and the second reagent of the test item B in the reaction container 17 that are stirred at the second reagent and stopped at the third stirring position Pg after the second reagent of the test item B is dispensed. Stir.

  The cleaning nozzle 36 cleans each reaction container 17 that has been measured and stopped at the cleaning position W. When the reaction container 17 into which the sample S2B has been dispensed is finished in the eighth cycle, all the reaction containers 17 are cleaned. Finish cleaning and stop the cleaning operation. When the cleaning operation is stopped, the analysis control unit 52 ends the analysis operation of the analysis unit 10.

  As described above, when the samples are not classified into the first and second groups, the dispensing of all the samples S1 and S2 to be inspected is finished in the tenth cycle, and the samples are classified into the first and second groups. Since the dispensing of all the samples S1 and S2 to be inspected is completed in the eighth cycle, the analysis operation of the analysis unit 10 can be completed earlier by two cycle times by classifying the samples into the first and second groups. it can. Thereby, inspection time can be shortened.

  Even when the inspection item B is not set to either the sample S1 or the sample S2, the analysis operation of the analysis unit 10 is completed by two cycle times earlier by classifying into the first and second groups. Can be made. Thereby, inspection time can be shortened.

  In addition, when classified into the first and second groups, the third group and the fourth group of the second group are preferentially assigned to each reaction vessel 17 that is sequentially cleaned by the cleaning nozzle 36. Then, the first and second sets of the first group may be assigned. In this case, the first reagent of the test item B set for each sample S1, S2 is dispensed to each reaction vessel 17 to which the third and fourth sets are assigned, and the test item set for each sample S1, S2 After the dispensing of the first reagent of B is completed, the first reagent of the inspection item A set for each sample S1, S2 is dispensed to each reaction container 17 to which the first and second groups are assigned. To. Thereby, inspection time can be shortened.

  Next, referring to FIG. 10 to FIG. 12, there are a plurality of samples to be inspected having two or more samples set with the second specific item and one or more samples set with the general item. The inspection items set for this sample are the objects to be inspected when they are not classified into the first and second groups by the second specific item and when they are classified into the first and second groups. An example of the dispensing operation of each sample and the reagent of each inspection item set in this sample will be described.

  FIG. 10 shows each sample to be inspected when it is not classified into the first and second groups according to the second specific item and when it is classified into the first and second groups, and this sample is set. It is the figure which showed the order of dispensing of the reagent of each test | inspection item.

  For example, two inspection items C and D are set for two samples S3 and S4 to be inspected. The inspection item C is, for example, a second specific item of the two reagent system, and the inspection item D is a general item of the two reagent system. In such a case, since the second specific item is set to the two samples S3 and S4, the classification unit 51 sets the sample S3 and the inspection item C as the first set, and sets the sample S4 and the inspection item C as the first group. A first group consisting of two sets, two sets, a second group consisting of two sets, the sample S3 and the inspection item D being the third group, and the sample S4 and the inspection item B being the fourth group; Can be classified.

  If the first to fourth groups are not classified into the first and second groups and are set to be dispensed in the order of the sample S3 and the sample S4, the analysis control unit 52 causes the cleaning nozzle 36 to The first and third sets are assigned to each reaction vessel 17 that is sequentially washed, and then the second and fourth sets are assigned. Then, the analysis control unit 52 causes each reaction container 17 to which the first and third sets are assigned to dispense the sample S3 for each inspection item C, D set in the sample S3, and each inspection item C, D After the dispensing of the sample S3 is completed, the sample S4 for each of the inspection items C and D set in the sample S4 is dispensed to each reaction vessel 17 to which the second and fourth groups are assigned.

  When the first to fourth groups are classified into the first and second groups, the analysis control unit 52 performs the first and second for each reaction container 17 that is sequentially cleaned by the cleaning nozzle 36. Are assigned, and then the third and fourth sets are assigned. And the analysis control part 52 dispenses the 1st reagent of the test item C set to each sample S3, S4 to each reaction container 17 which allocated the 1st and 2nd group, and makes each sample S3, S4 After the dispensing of the first reagent of the set inspection item C is completed, the first reagent of the inspection item D set for each sample S3, S4 is assigned to each reaction container 17 to which the third and fourth groups are assigned. To dispense.

  When classified into the first and second groups, the third group and the fourth group of the second group are preferentially assigned to each reaction vessel 17 that is sequentially cleaned by the cleaning nozzle 36. Then, the first and second sets of the first group may be assigned. In this case, the first reagent of the test item D set in each sample S3, S4 is dispensed to each reaction container 17 assigned the third and fourth groups, and the test item set in each sample S3, S4. After dispensing of the first reagent of D is completed, the first reagent of the inspection item C set in each of the samples S3 and S4 is dispensed to each reaction container 17 to which the first and second sets are assigned. To.

  FIG. 11 shows the details of each sample to be inspected when not classified into the first and second groups by the second specific item and the dispensing operation of the reagent of each inspection item set in this sample. FIG.

  The sample table 12 holds two sample containers 11. Of the two sample containers 11, one sample container 11 stores a sample S3 and the other sample container 11 stores a sample S4.

  The analysis control unit 52 assigns the sample S3 and the inspection item C to one reaction container 17 to be cleaned at the cleaning position W, and the reaction container 17 to which the sample S3 and the inspection item C are assigned stops at the cleaning position W. Then, after one cycle time, the sample S3 and the inspection item D are assigned to one reaction vessel 17 that is stopped and cleaned at the cleaning position W.

  Here, since the inspection item C is the second specific item, for the reaction container 17 to which the sample S3 and the inspection item C are assigned, the first item of the inspection item C is stopped when stopped at the first reagent discharge position Pb. It is necessary to dispense the sample S3 when one reagent is dispensed and stopped at the sample aspirating / discharging position Pd after 4 cycle times after stopping at the sample discharging position Pa. Therefore, since dispensing of sample 3 requires 4 cycle times, the reaction vessel 17 to which sample S3 and inspection item D are assigned stops at the cleaning position W, and then stops at the cleaning position W after 1 cycle time. The reaction vessel 17 to be cleaned becomes the first unassigned reaction vessel 17 to be cleaned, and the reaction vessel 17 stops at the cleaning position W one cycle time after the reaction vessel 17 stops at the cleaning position W. Becomes a second reaction vessel 17 which is to be washed but not assigned.

  In addition, the analysis control unit 52 applies the one reaction container 17 that is stopped and cleaned at the cleaning position W one cycle after the second unassigned reaction container 17 stops at the cleaning position W. The sample S4 and the inspection item C are allotted, and the reaction container 17 to which the sample S4 and the inspection item C are assigned stops at the cleaning position W, and then stops at the cleaning position W after one cycle time, and performs one reaction. The sample S4 and the inspection item D are assigned to the container 17.

  When the sample S3 and the inspection item C are assigned, and the reaction container 17 that has been emptied after being cleaned is stopped at the sample discharge position Pa, the first cycle is assumed.

  In the second cycle, the empty reaction container 17 to which the sample S3 and the inspection item D are assigned stops at the sample discharge position Pa. The empty reaction container 17 that has been assigned the sample S3 and the inspection item C and stopped at the sample discharge position Pa in the first cycle stops at the first reagent discharge position Pb. The sample dispensing probe 19 dispenses the sample S3 in the sample container 11 as the sample S3D for the inspection item D into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1C of the inspection item C of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  In the third cycle, the unassigned first reaction container 17 stops at the sample discharge position Pa. The reaction container 17 into which the sample S3D has been dispensed in the second cycle stops at the first reagent discharge position Pb. The first reagent dispensing probe 23 dispenses the first reagent R1D of the inspection item D of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  In the fourth cycle, the unassigned second reaction container 17 stops at the sample discharge position Pa.

  In the fifth cycle, the empty reaction container 17 to which the sample S4 and the inspection item C are assigned stops at the sample discharge position Pa. The reaction container 17 into which the sample S3D and the first reagent R1D have been dispensed stops at the first stirring position Pc. The reaction container 17 into which the first reagent R1C has been dispensed in the second cycle stops at the sample suction / discharge position Pd. The first stirrer 26 stirs the sample S3D and the first reagent R1D in the reaction vessel 17 stopped at the first stirring position Pc. The sample dispensing probe 19 dispenses the sample S3 in the sample container 11 as the sample S3C for the inspection item C into the reaction container 17 stopped at the sample suction / discharge position Pd.

  The dispensing of the sample S3 is completed by dispensing the sample S3C into the reaction vessel 17 stopped at the sample suction / discharge position Pd in the fifth cycle.

  In the sixth cycle, the empty reaction container 17 to which the sample S4 and the inspection item D are assigned stops at the sample discharge position Pa. The empty reaction container 17 that is assigned the sample S4 and the inspection item C and stops at the sample discharge position Pa in the fifth cycle stops at the first reagent discharge position Pb. The reaction container 17 into which the first reagent R1C and the sample S3C have been dispensed stops at the second stirring position Pe. The sample dispensing probe 19 dispenses the sample S4 in the sample container 11 as the sample S4D for the inspection item D into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1C of the inspection item C of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb. The second stirring bar 28 stirs the first reagent R1C and the sample S3C in the reaction vessel 17 stopped at the second stirring position Pe.

  In the seventh cycle, the reaction container 17 into which the sample S4D has been dispensed in the sixth cycle stops at the first reagent discharge position Pb. The first reagent dispensing probe 23 dispenses the first reagent R1D of the inspection item D of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  By dispensing the first reagent R1D into the reaction container 17 stopped at the first reagent discharge position Pb in the seventh cycle, the first of all the inspection items C and D set in all the samples S3 and S4 to be inspected. The dispensing of one reagent is completed.

  In the ninth cycle, the reaction container 17 into which the sample S4D and the first reagent R1D have been dispensed stops at the first stirring position Pc. The reaction container 17 into which the first reagent R1C has been dispensed in the sixth cycle stops at the sample suction / discharge position Pd. The first stirrer 26 stirs the sample S4D and the first reagent R1D in the reaction vessel 17 stopped at the first stirring position Pc. The sample dispensing probe 19 dispenses the sample S4 in the sample container 11 as the sample S4C for the inspection item C into the reaction container 17 stopped at the sample suction / discharge position Pd.

  The dispensing of the sample S4C into the reaction vessel 17 stopped at the sample suction / discharge position Pd in the ninth cycle is completed, and the dispensing of all the samples S3 and S4 to be inspected is completed. .

  In the tenth cycle, the reaction container 17 into which the first reagent R1C and the sample S4C have been dispensed stops at the second stirring position Pe. The second stirring bar 28 stirs the first reagent R1C and the sample S4C in the reaction vessel 17 stopped at the second stirring position Pe.

  The second reagent dispensing probe 30 dispenses the second reagent of the inspection item C into the reaction container 17 that stops at the second reagent discharge position Pf after the first reagent R1C and the sample S3C are stirred in the sixth cycle. Then, after the sample S3D and the first reagent R1D are stirred in the fifth cycle, the second reagent of the inspection item D is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  In addition, the second reagent dispensing probe 30 applies the second reagent of the inspection item C to the reaction container 17 that stops at the second reagent discharge position Pf after the first reagent R1C and the sample S4C are stirred in the tenth cycle. After the sample S4D and the first reagent R1D are stirred in the ninth cycle, the second reagent of the test item D is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  The third stirrer 33 includes the first reagent R1C, the sample S3C, and the second reagent of the test item C in the reaction vessel 17 that stops at the third stirring position Pg after the second reagent of the test item C is dispensed. The sample S3D, the first reagent R1D, and the second reagent of the test item D in the reaction container 17 that stops at the third stirring position Pg after the second reagent of the test item D is dispensed are stirred. .

  In addition, the third stirring bar 33 includes the first reagent R1C, the sample S4C, and the first item of the inspection item C in the reaction container 17 that stops at the third stirring position Pg after the second reagent of the inspection item C is dispensed. The sample S4D, the first reagent R1D, and the second reagent of the test item D in the reaction container 17 that are stirred at the second reagent and stopped at the third stirring position Pg after the second reagent of the test item D is dispensed. Stir.

  The cleaning nozzle 36 cleans each reaction container 17 that has been measured and stopped at the cleaning position W, and when the cleaning of the reaction container 17 into which the first reagent R1D has been dispensed is completed in the seventh cycle, The cleaning operation is stopped after the cleaning of all the reaction vessels 17 into which the reagents of the samples S3 and S4 and the inspection items C and D are dispensed is finished. When the cleaning operation is stopped, the analysis control unit 52 ends the analysis operation of the analysis unit 10.

  FIG. 12 shows the details of each sample to be inspected when classified into the first and second groups by the second specific item and the reagent dispensing operation of each inspection item set in this sample. FIG.

  The analysis control unit 52 assigns the sample S3 and the inspection item C to one reaction container 17 to be cleaned at the cleaning position W, and the reaction container 17 to which the sample S3 and the inspection item C are assigned stops at the cleaning position W. Then, after one cycle time, the sample S4 and the inspection item C are assigned to one reaction container 17 that is stopped and cleaned at the cleaning position W.

  In addition, the analysis control unit 52 stops the reaction container 17 to which the sample S4 and the inspection item C are assigned at the cleaning position W and stops at the cleaning position W one cycle after the reaction container 17 is cleaned. The sample S3 and the inspection item D are assigned to the sample, and the reaction container 17 to which the sample S3 and the inspection item D are assigned stops at the cleaning position W, and then stops at the cleaning position W after one cycle time and is cleaned. The sample S4 and the inspection item D are assigned to the reaction container 17 in FIG.

  When the sample S3 and the inspection item C are assigned, and the reaction container 17 that has been emptied after being cleaned is stopped at the sample discharge position Pa, the first cycle is assumed.

  In the second cycle, the empty reaction container 17 to which the sample S4 and the inspection item C are assigned stops at the sample discharge position Pa. The empty reaction container 17 that has been assigned the sample S3 and the inspection item C and stopped at the sample discharge position Pa in the first cycle stops at the first reagent discharge position Pb. The first reagent dispensing probe 23 dispenses the first reagent R1C of the inspection item C of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  In the third cycle, the empty reaction container 17 to which the sample S3 and the inspection item D are assigned stops at the sample discharge position Pa. The empty reaction container 17 that is assigned the sample S4 and the inspection item C and stops at the sample discharge position Pa in the second cycle stops at the first reagent discharge position Pb. The sample dispensing probe 19 dispenses the sample S3 in the sample container 11 as the sample S3D for the inspection item D into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1C of the inspection item C of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  With the dispensing of the first reagent R1C into the reaction container 17 stopped at the first reagent discharge position Pb in the third cycle, the dispensing of the first reagent of each set of inspection items C classified into the first group is finish.

  In the fourth cycle, the reaction container 17 to which the sample S4 and the inspection item D are assigned stops at the sample discharge position Pa. The reaction container 17 into which the sample S3D has been dispensed in the third cycle stops at the first reagent discharge position Pb. The sample dispensing probe 19 dispenses the sample S4 in the sample container 11 as the sample S4D for the inspection item D into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1D of the inspection item D of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  In the fifth cycle, the reaction container 17 into which the sample S4D has been dispensed in the fourth cycle stops at the first reagent discharge position Pb. The reaction container 17 into which the first reagent R1C has been dispensed in the second cycle stops at the sample suction / discharge position Pd. The first reagent dispensing probe 23 dispenses the first reagent R1D of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb. The sample dispensing probe 19 dispenses the sample S3 in the sample container 11 as the sample S3C for the inspection item C into the reaction container 17 stopped at the sample suction / discharge position Pd.

  Dispensing the first reagent of each set of inspection items D classified into the second group by dispensing the first reagent R1D into the reaction container 17 stopped at the first reagent discharge position Pb in the fifth cycle is as follows. finish.

  In the sixth cycle, the reaction container 17 into which the sample S3D and the first reagent R1D have been dispensed stops at the first stirring position Pc. The reaction container 17 into which the first reagent R1C has been dispensed in the third cycle stops at the sample suction / discharge position Pd. The reaction container 17 into which the first reagent R1C and the sample S3C have been dispensed stops at the second stirring position Pe.

  In the sixth cycle, the first stirrer 26 stirs the sample S3D and the first reagent R1D in the reaction vessel 17 stopped at the first stirring position Pc. The sample dispensing probe 19 dispenses the sample S4 in the sample container 11 as the sample S4C for the inspection item C into the reaction container 17 stopped at the sample suction / discharge position Pd. The second stirring bar 28 stirs the first reagent R1C and the sample S3C in the reaction vessel 17 stopped at the second stirring position Pe.

  By dispensing the sample S4C into the reaction vessel 17 stopped at the sample suction / discharge position Pd in the sixth cycle, dispensing of all the samples S3 and S4 to be inspected is completed.

  In the seventh cycle, the reaction container 17 into which the sample S4D and the first reagent R1D have been dispensed stops at the first stirring position Pc. The reaction container 17 into which the first reagent R1C and the sample S4C have been dispensed stops at the second stirring position Pe. The first stirrer 26 stirs the sample S4D and the first reagent R1D in the reaction vessel 17 stopped at the first stirring position Pc. The second stirring bar 28 stirs the first reagent R1C and the sample S4C in the reaction vessel 17 stopped at the second stirring position Pe.

  The second reagent dispensing probe 30 dispenses the second reagent of the inspection item C into the reaction container 17 that stops at the second reagent discharge position Pf after the first reagent R1C and the sample S3C are stirred in the sixth cycle. Then, after the first reagent R1C and the sample S4C are stirred in the seventh cycle, the second reagent of the inspection item C is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  In addition, the second reagent dispensing probe 30 applies the second reagent of the inspection item D to the reaction container 17 that stops at the second reagent discharge position Pf after the sample S3D and the first reagent R1D are stirred in the sixth cycle. After the sample S4D and the first reagent R1D are stirred in the seventh cycle, the second reagent of the inspection item D is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  The third stirrer 33 includes the first reagent R1C, the sample S3C, and the second reagent of the test item C in the reaction vessel 17 that stops at the third stirring position Pg after the second reagent of the test item C is dispensed. The first reagent R1C, the sample S4C, and the second reagent of the inspection item C in the reaction vessel 17 that stops at the third stirring position Pg after the second reagent of the inspection item C is dispensed are stirred. .

  The third stirrer 33 also includes the sample S3D, the first reagent R1D, and the first of the inspection items D in the reaction container 17 that stop at the third stirring position Pg after the second reagent of the inspection item D is dispensed. The sample S4D, the first reagent R1D, and the second reagent of the test item D in the reaction container 17 that are stirred at the second reagent and stopped at the third stirring position Pg after the second reagent of the test item D is dispensed. Stir.

  The cleaning nozzle 36 cleans each reaction container 17 that has been measured and stopped at the cleaning position W, and when the cleaning of the reaction container 17 into which the first reagent R1D has been dispensed is completed in the fifth cycle, The cleaning operation is stopped after the cleaning of all the reaction vessels 17 into which the reagents of the samples S3 and S4 and the inspection items C and D are dispensed is finished. When the cleaning operation is stopped, the analysis control unit 52 ends the analysis operation of the analysis unit 10.

  As described above, when the liquids are not classified into the first and second groups, the dispensing of the first reagents of all the inspection items C and D set in all the samples S3 and S4 to be inspected in the seventh cycle is completed. When the classification is made into the first and second groups, the dispensing of the first reagent of all the inspection items C and D set in all the samples S3 and S4 to be inspected in the fifth cycle is finished. Thus, the analysis operation of the analysis unit 10 can be completed earlier by two cycle times by classifying the data into the first and second groups. Thereby, inspection time can be shortened.

  Even if the inspection item B is not set to either the sample S3 or the sample S4, it is not classified into the first and second groups by classifying into the first and second groups. The analysis operation of the analysis unit 10 can be completed earlier than the case. Thereby, inspection time can be shortened.

  Next, referring to FIGS. 13 to 15, there are a plurality of samples to be inspected having two or more samples set with the third specific item and one or more samples set with the general item. The inspection items set for this sample are the objects to be inspected when they are not classified into the first and second groups by the third specific item and when they are classified into the first and second groups. An example of the dispensing operation of each sample and the reagent of each inspection item set in this sample will be described.

  FIG. 13 shows each sample to be inspected when it is not classified into the first and second groups according to the third specific item and when it is classified into the first and second groups, and this sample is set. It is the figure which showed the order of dispensing of the reagent of each test | inspection item.

  Two inspection items E and F are set for the two samples S5 and S6 to be inspected. The inspection item E is a third specific item of the two reagent system, and the inspection item F is a general item of the two reagent system. In such a case, since the third specific item is set to the two samples S5 and S6, the classification unit 51 sets the sample S5 and the inspection item E as the first set, and sets the sample S6 and the inspection item E to the first sample. A first group consisting of two sets, two sets, a second group consisting of two sets, the sample S5 and the inspection item F as the third group, and the sample S6 and the inspection item F as the fourth group; Can be classified.

  If the first to fourth groups are not classified into the first and second groups, the sample S5 and the sample S6 are set to be dispensed in this order. The analysis controller 52 assigns the first and third sets to the reaction containers 17 that are sequentially cleaned by the cleaning nozzle 36, and then assigns the second and fourth sets. Then, the analysis control unit 52 causes the sample S5 for each inspection item E and F set in the sample S5 to be dispensed to each reaction container 17 to which the first and third sets are assigned, and each inspection item E and F After the dispensing of the sample S5 for use is completed, the sample S6 for each of the inspection items E and F set in the sample S6 is dispensed to each reaction vessel 17 to which the second and fourth groups are assigned.

  When the first to fourth groups are classified into the first and second groups, the analysis control unit 52 performs the first and second for each reaction container 17 that is sequentially cleaned by the cleaning nozzle 36. Are assigned, and then the third and fourth sets are assigned. And the analysis control part 52 dispenses the 1st reagent of the test item E set to each sample S5, S6 to each reaction container 17 which allocated the 1st and 2nd group, and makes each sample S5, S6 After the dispensing of the first reagent of the set inspection item E is completed, the first reagent of the inspection item F set in each sample S5, S6 is assigned to each reaction container 17 to which the third and fourth groups are assigned. To dispense.

  FIG. 14 shows the details of each sample to be inspected when not classified into the first and second groups by the third specific item, and the reagent dispensing operation of each inspection item set for this sample. FIG.

  The sample table 12 holds two sample containers 11, and of the two sample containers 11, one sample container 11 contains a sample S5 and the other sample container 11 contains a sample S6.

  The analysis control unit 52 assigns the sample S5 and the inspection item E to one reaction container 17 to be cleaned at the cleaning position W, and the cleaning is performed two cycle times after the reaction container 17 stops at the cleaning position W. The sample S5 and the inspection item F are assigned to one reaction vessel 17 that stops at the position W and is cleaned.

  Here, since the inspection item E is the third specific item, the reaction container 17 to which the sample S5 and the inspection item E are assigned stops at the cleaning position W after one cycle time after stopping at the cleaning position W. When the reaction container 17 stops at the first reagent discharge position Pb, it is necessary to cause the first reagent dispensing probe 23 to suck the cleaning liquid of the first reagent container 13 and discharge it to the first reagent cleaning tank 25 for cleaning. There is. From this, one reaction container 17 that stops at the cleaning position W after one cycle time after the reaction container 17 to which the sample S5 and the inspection item E are allocated stops at the cleaning position W is assigned to the one to be cleaned. The first reaction vessel 17 is not present.

  In addition, the analysis control unit 52 stops the reaction vessel 17 to which the sample S5 and the inspection item F are assigned at the washing position W, and then stops at the washing position W one cycle after the reaction vessel 17 is cleaned. The sample S6 and the inspection item E are assigned to the sample, and the sample for one reaction vessel 17 that is stopped and cleaned at the cleaning position W two cycles after the reaction vessel 17 stops at the cleaning position W. S6 and inspection item F are assigned.

  Here, since the inspection item E is the third specific item, the reaction vessel 17 to which the sample S6 and the inspection item E are assigned stops at the cleaning position W and then stops at the cleaning position W after one cycle time. When the reaction container 17 stops at the first reagent discharge position Pb, it is necessary to cause the first reagent dispensing probe 23 to suck the cleaning liquid of the first reagent container 13 and discharge it to the first reagent cleaning tank 25 for cleaning. There is. From this, one reaction container 17 that stops at the cleaning position W after one cycle time after the reaction container 17 to which the sample S6 and the inspection item E are allocated stops at the cleaning position W is assigned to the one to be cleaned. No second reaction vessel 17 is obtained.

  When the sample S5 and the inspection item E are assigned and the reaction container 17 that has been emptied after being cleaned is stopped at the sample discharge position Pa, the first cycle is defined.

  In the first cycle, the sample dispensing probe 19 dispenses the sample S5 in the sample container 11 as the sample S5E for the inspection item E into the reaction container 17 stopped at the sample discharge position Pa.

  In the second cycle, the unassigned first reaction vessel 17 stops at the sample discharge position Pa. The reaction container 17 into which the sample S5E has been dispensed in the first cycle stops at the first reagent discharge position Pb. The first reagent dispensing probe 23 dispenses the first reagent R1E of the inspection item E of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  In the third cycle, the reaction container 17 to which the sample S5 and the inspection item F are assigned stops at the sample discharge position Pa. The first reaction container 17 that is not assigned stops at the first reagent discharge position Pb. The sample dispensing probe 19 dispenses the sample S5 in the sample container 11 as the sample S5F for the inspection item F into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 performs cleaning by sucking the cleaning liquid of the first reagent container 13 held in the first reagent rack 14 and discharging the cleaning liquid to the first reagent cleaning tank 25.

  The dispensing of the sample S5 is completed by dispensing the sample S5F into the reaction vessel 17 stopped at the sample discharge position Pa in the third cycle.

  In the fourth cycle, the reaction container 17 to which the sample S6 and the inspection item E are assigned stops at the sample discharge position Pa. The reaction container 17 into which the sample S5F has been dispensed in the third cycle stops at the first reagent discharge position Pb. The reaction container 17 into which the sample S5E and the first reagent R1E have been dispensed stops at the first stirring position Pc. The sample dispensing probe 19 dispenses the sample S6 in the sample container 11 as the sample S6E for the inspection item E into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1F of the inspection item F of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb. The first stirrer 26 stirs the sample S5E and the first reagent R1E in the reaction vessel 17 stopped at the first stirring position Pc.

  In the fifth cycle, the unassigned second reaction container 17 stops at the sample discharge position Pa. The reaction container 17 into which the sample S6E has been dispensed in the fourth cycle stops at the first reagent discharge position Pb. The first reagent dispensing probe 23 dispenses the first reagent R1E of the inspection item E of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  In the sixth cycle, the reaction container 17 to which the sample S6 and the inspection item F are assigned stops at the sample discharge position Pa. The unassigned second reaction container 17 stops at the first reagent discharge position Pb. The reaction container 17 into which the sample S5F and the first reagent R1F have been dispensed stops at the first stirring position Pc.

  In the sixth cycle, the sample dispensing probe 19 dispenses the sample S6 of the sample container 11 as the sample S6F for the inspection item F into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 performs cleaning by sucking the cleaning liquid in the first reagent container 13 and discharging the cleaning liquid into the first reagent cleaning tank 25. The first stirrer 26 stirs the sample S5F and the first reagent R1F in the reaction vessel 17 stopped at the first stirring position Pc.

  By dispensing the sample S6F into the reaction container 17 stopped at the sample discharge position Pa in the sixth cycle, the dispensing of the sample S6 is completed, and the dispensing of all the samples S5 and S6 to be inspected is completed.

  In the seventh cycle, the reaction container 17 into which the sample S6F has been dispensed in the sixth cycle stops at the first reagent discharge position Pb. The reaction container 17 into which the sample S6E and the first reagent R1E are dispensed stops at the first stirring position Pc. The first reagent dispensing probe 23 dispenses the first reagent R1F of the inspection item F of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb. The first stirrer 26 agitates the sample S6E and the first reagent R1E in the reaction vessel 17 stopped at the first agitation position Pc.

  By dispensing the first reagent R1F into the reaction container 17 stopped at the first reagent discharge position Pb in the seventh cycle, the first of all the inspection items E and F set in all the samples S5 and S6 to be inspected. The dispensing of one reagent is completed.

  In the ninth cycle, the reaction vessel 17 into which the sample S6F and the first reagent R1F have been dispensed stops at the first stirring position Pc. The first stirrer 26 agitates the sample S6F and the first reagent R1F in the reaction vessel 17 stopped at the first agitation position Pc.

  The second reagent dispensing probe 30 dispenses the second reagent of the inspection item E into the reaction container 17 that stops at the second reagent discharge position Pf after the sample S5E and the first reagent R1E are stirred in the fourth cycle. Then, after the sample S5F and the first reagent R1F are agitated in the sixth cycle, the second reagent of the inspection item F is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  Further, the second reagent dispensing probe 30 applies the second reagent of the inspection item E to the reaction container 17 that stops at the second reagent discharge position Pf after the sample S6E and the first reagent R1E are stirred in the seventh cycle. After the sample S6F and the first reagent R1F are stirred in the ninth cycle, the second reagent of the inspection item F is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  The third stirring bar 33 stirs the sample S5E, the first reagent R1E, and the second reagent of the inspection item E in the reaction container 17 stopped at the third stirring position Pg, and the reaction container 17 stopped at the third stirring position Pg. The sample S5F, the first reagent R1F, and the second reagent of the inspection item F are stirred. The third stirrer 33 stirs the sample S6E, the first reagent R1E, and the second reagent of the inspection item E in the reaction vessel 17 that stops at the third stirring position Pg, and stops at the third stirring position Pg. The sample S6F, the first reagent R1F, and the second reagent of the inspection item F in the container 17 are agitated.

  The cleaning nozzle 36 cleans each reaction container 17 that has been measured and stopped at the cleaning position W, and when the cleaning of the reaction container 17 into which the first reagent R1F has been dispensed is completed in the seventh cycle, The cleaning operation is stopped after the cleaning of all the reaction vessels 17 into which the reagents of the samples S5 and S6 and the inspection items E and F have been dispensed is completed. When the cleaning operation is stopped, the analysis control unit 52 ends the analysis operation of the analysis unit 10.

  FIG. 15 shows the details of each sample to be inspected when classified into the first and second groups by the third specific item and the reagent dispensing operation of each inspection item set in this sample. FIG.

  The analysis control unit 52 assigns the sample S5 and the inspection item E to one reaction container 17 to be cleaned at the cleaning position W, and the cleaning is performed one cycle time after the reaction container 17 stops at the cleaning position W. The sample S6 and the inspection item E are assigned to one reaction vessel 17 that stops at the position W and is cleaned.

  Here, since the inspection item E is the third specific item, and the next allocation of the sample S6 and the inspection item E is the sample S5 and the inspection item F, the allocation of the sample S6 and the inspection item E and the sample S5 and It is necessary to cause the first reagent dispensing probe 23 to suck the cleaning liquid of the first reagent container 13 between the inspection item F and discharge it to the first reagent cleaning tank 25 for cleaning. From this, one reaction container 17 that stops at the cleaning position W after one cycle time after the reaction container 17 to which the sample S6 and the inspection item E are allocated stops at the cleaning position W is assigned to the one to be cleaned. The first reaction vessel 17 is not present.

  In addition, the analysis control unit 52 performs the cleaning on the one reaction container 17 that is stopped at the cleaning position W one cycle after the first unassigned reaction container 17 stops at the cleaning position W and is cleaned. The sample S5 and the inspection item F are assigned, and after one cycle time after the reaction vessel 17 stops at the cleaning position W, the sample S6 and the sample S6 and The inspection item F is assigned.

  When the sample S5 and the inspection item E are assigned and the reaction container 17 that has been emptied after being cleaned is stopped at the sample discharge position Pa, the first cycle is defined.

  In the first cycle, the sample dispensing probe 19 dispenses the sample S5 in the sample container 11 as the sample S5E for the inspection item E into the reaction container 17 stopped at the sample discharge position Pa.

  In the second cycle, the empty reaction container 17 to which the sample S6 and the inspection item E are assigned stops at the sample discharge position Pa. The reaction container 17 into which the sample S5E has been dispensed in the first cycle stops at the first reagent discharge position Pb. The sample dispensing probe 19 dispenses the sample S6 in the sample container 11 as the sample S6E for the inspection item E into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1E of the inspection item E of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  In the third cycle, the unassigned first reaction container 17 stops at the sample discharge position Pa. The reaction container 17 into which the sample S6E has been dispensed in the second cycle stops at the first reagent discharge position Pb. The first reagent dispensing probe 23 dispenses the first reagent R1E of the inspection item E of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  With the first reagent R1E being dispensed into the reaction container 17 stopped at the first reagent discharge position Pb in the third cycle, the dispensing of the first reagent of each set of inspection items E classified into the first group is finish.

  In the fourth cycle, the reaction container 17 to which the sample S5 and the inspection item F are assigned stops at the sample discharge position Pa. The first reaction container 17 that is not assigned stops at the first reagent discharge position Pb. The reaction container 17 into which the sample S5E and the first reagent R1E have been dispensed stops at the first stirring position Pc.

  In the fourth cycle, the sample dispensing probe 19 dispenses the sample S5 in the sample container 11 as the sample S5F for the inspection item F into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 performs cleaning by sucking the cleaning liquid in the first reagent container 13 and discharging the cleaning liquid into the first reagent cleaning tank 25. The first stirrer 26 stirs the sample S5E and the first reagent R1E in the reaction vessel 17 stopped at the first stirring position Pc.

  In the fifth cycle, the reaction container 17 to which the sample S6 and the inspection item F are assigned stops at the sample discharge position Pa. The reaction container 17 into which the sample S5F has been dispensed in the fourth cycle stops at the first reagent discharge position Pb. The reaction container 17 into which the sample S6E and the first reagent R1E are dispensed stops at the first stirring position Pc.

  In the fifth cycle, the sample dispensing probe 19 dispenses the sample S6 of the sample container 11 as the sample S6F for the inspection item F into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1F of the inspection item F of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb. The first stirrer 26 agitates the sample S6E and the first reagent R1E in the reaction vessel 17 stopped at the first agitation position Pc.

  By dispensing the sample S6F into the reaction container 17 stopped at the sample discharge position Pa in the fifth cycle, dispensing of all the samples S5 and S6 to be inspected is completed.

  In the sixth cycle, the reaction container 17 into which the sample S6F has been dispensed in the fifth cycle stops at the first reagent discharge position Pb. The first reagent dispensing probe 23 dispenses the first reagent R1F of the inspection item F of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  With the first reagent R1F being dispensed into the reaction vessel 17 stopped at the first reagent discharge position Pb in the sixth cycle, the first reagent in each group of the inspection items F classified into the first group is dispensed. finish.

  In the seventh cycle, the reaction container 17 into which the sample S5F and the first reagent R1F have been dispensed stops at the first stirring position Pc. The first stirrer 26 stirs the sample S5F and the first reagent R1F in the reaction vessel 17 stopped at the first stirring position Pc.

  In the eighth cycle, the reaction container 17 into which the sample S6F and the first reagent R1F have been dispensed stops at the first stirring position Pc. The first stirrer 26 agitates the sample S6F and the first reagent R1F in the reaction vessel 17 stopped at the first agitation position Pc.

  The second reagent dispensing probe 30 dispenses the second reagent of the inspection item E into the reaction container 17 that stops at the second reagent discharge position Pf after the sample S5E and the first reagent R1E are stirred in the fourth cycle. Then, after the sample S6E and the first reagent R1E are stirred in the fifth cycle, the second reagent of the inspection item E is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  In addition, the second reagent dispensing probe 30 applies the second reagent of the inspection item F to the reaction container 17 that stops at the second reagent discharge position Pf after the sample S5F and the first reagent R1F are stirred in the seventh cycle. After the sample S6F and the first reagent R1F are stirred in the eighth cycle, the second reagent of the inspection item F is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  The third stirring bar 33 stirs the sample S5E, the first reagent R1E, and the second reagent of the inspection item E in the reaction container 17 stopped at the third stirring position Pg, and the reaction container 17 stopped at the third stirring position Pg. The sample S6E, the first reagent R1E, and the second reagent of the inspection item E are stirred. Further, the third stirring bar 33 stirs the sample S5F, the first reagent R1F, and the second reagent of the inspection item F in the reaction vessel 17 that stops at the third stirring position Pg, and stops at the third stirring position Pg. The sample S6F, the first reagent R1F, and the second reagent of the inspection item F in the container 17 are agitated.

  The cleaning nozzle 36 cleans each reaction container 17 that has been measured and stopped at the cleaning position W, and when cleaning of the reaction container 17 into which the first reagent R1F has been dispensed is completed in the sixth cycle, The cleaning operation is stopped after the cleaning of all the reaction vessels 17 into which the reagents of the samples S5 and S6 and the inspection items E and F have been dispensed is completed. When the cleaning operation is stopped, the analysis control unit 52 ends the analysis operation of the analysis unit 10.

  As described above, when the liquids are not classified into the first and second groups, the dispensing of the first reagents of all the inspection items E and F set in all the samples S5 and S6 to be inspected in the seventh cycle is completed. When the classification is made into the first and second groups, the dispensing of the first reagent of all the inspection items E and F set in all the samples S5 and S6 to be inspected in the sixth cycle is finished. Thus, the analysis operation of the analysis unit 10 can be completed earlier by one cycle time by classifying the data into the first and second groups. Thereby, inspection time can be shortened.

  In addition, when it is classified into the first and second groups, the first and third groups are preferentially assigned to the reaction containers 17 that are sequentially cleaned by the cleaning nozzle 36, and then the first And the second set may be assigned. In this case, the first reagent of the test item F set in each sample S5, S6 is dispensed to each reaction container 17 to which the third and fourth sets are assigned, and the test item set in each sample S5, S6. After the dispensing of the first reagent of F is completed, the first reagent of the inspection item E set in each of the samples S5 and S6 is dispensed to each reaction container 17 to which the first and second sets are assigned. To. Thereby, after the dispensing of the reagent of the affected test item, the reagent of the affecting test item is dispensed, and it is not necessary to clean the first reagent dispensing probe 23 with the cleaning liquid. , Inspection time can be shortened.

  Next, referring to FIG. 16 to FIG. 20, there are a plurality of samples to be inspected having two or more samples set with the fourth specific item and one or more samples set with the general item. Each sample to be inspected when the inspection item set for this sample is not classified into the first and second groups by the fourth specific item and when it is classified into the first and second groups An example of the dispensing operation of the reagent for each test item set in the sample will be described.

  FIG. 16 shows each sample to be inspected when it is not classified into the first and second groups and when it is classified into the first and second groups according to the fourth specific item, and set for this sample. It is the figure which showed the order of dispensing of the reagent of each test | inspection item.

  Two inspection items G and H are set for the two samples S7 and S8 to be inspected. The inspection item G is a fourth specific item, and the inspection item H is a two-reagent system general item. In such a case, since the fourth specific item is set to the samples S7 and S8, the classification unit 51 sets the sample S7 and the inspection item G as the first set, and sets the sample S8 and the inspection item G as the second group. Classification into a first group consisting of two sets as a set, and a second group consisting of two sets where the sample S7 and the inspection item H are the third set and the sample S8 and the inspection item H are the fourth set can do.

  If the first to fourth groups are not classified into the first and second groups and are set to be dispensed in the order of the sample S7 and the sample S8, the analysis control unit 52 causes the cleaning nozzle 36 to The first and third sets are assigned to each reaction vessel 17 that is sequentially washed, and then the second and fourth sets are assigned. Then, the analysis control unit 52 causes each of the test items G and H set in the sample S7 to be dispensed to each reaction container 17 to which the first and third sets are assigned, and each of the test items G and H is dispensed. After the dispensing of the sample S7 for use is completed, the sample S8 for each of the inspection items G and H set in the sample S8 is dispensed to each reaction vessel 17 to which the second and fourth groups are assigned.

  When the first to fourth groups are classified into the first and second groups, the analysis control unit 52 performs the first and second for each reaction container 17 that is sequentially cleaned by the cleaning nozzle 36. Are assigned, and then the third and fourth sets are assigned. And the analysis control part 52 dispenses the 1st reagent of the test item G set to each sample S7, S8 to each reaction container 17 which allocated the 1st and 2nd group, and makes each sample S7, S8 After the dispensing of the first reagent of the set test item G is completed, each of the reaction containers 17 assigned with the third and fourth groups is not the fourth specific item set for each sample S7, S8. The first reagent of the inspection item H is dispensed.

  In addition, when it is classified into the first and second groups, the first and third groups are preferentially assigned to the reaction containers 17 that are sequentially cleaned by the cleaning nozzle 36, and then the first And the second set may be assigned. In this case, the first reagent of the test item H set in each sample S7, S8 is dispensed to each reaction container 17 assigned the third and fourth groups, and the test item set in each sample S7, S8. After the dispensing of the first reagent of H is finished, the first reagent of the inspection item G set in each sample S7, S8 is dispensed to each reaction container 17 to which the first and second sets are assigned. To.

  FIG. 17 is a diagram showing the positions of the reaction vessels 17 assigned to the samples S7 and S8 and the inspection items G and H when they are not classified into the first and second groups by the fourth specific item. is there.

  The analysis control unit 52 assigns the sample S7 and the inspection item G to one reaction container 17 to be cleaned at the cleaning position W, and the cleaning is performed one cycle time after the reaction container 17 stops at the cleaning position W. The sample S7 and the inspection item H are assigned to one reaction vessel 17 that stops at the position W and is cleaned.

  In addition, the analysis control unit 52 stops the reaction vessel 17 to which the sample S7 and the inspection item H are assigned at the washing position W, and then stops at the washing position W one cycle after the reaction vessel 17 is cleaned. The sample S8 and the inspection item G are assigned to the sample, and the sample for one reaction vessel 17 in which the reaction vessel 17 stops at the washing position W after one cycle time after the reaction vessel 17 stops at the washing position W and is cleaned. S8 and inspection item H are assigned.

  When the reaction container 17 to which the sample S7 and the inspection item G are assigned stops at the sample discharge position Pa, the reaction container 17 to which the sample S7 and the inspection item H are assigned is the position of the reaction container 17 to which the sample S7 and the inspection item G are assigned. Is stopped at the other end position where the center angle θ is one end position of the circular arc of the central angle θ, the reaction vessel 17 assigned the sample S8 and the inspection item H stops at the seventh washing position W7, and the sample S8 and the inspection item H are assigned. The reaction vessel 17 stops at the other end position where the seventh washing position W7 is the one end position of the arc having the central angle θ.

  Then, the analysis control unit 52 separates the first reagent of the test item G at the first reagent discharge position Pb with respect to the reaction container 17 to which the sample S7 and the test item G and the sample S8 and the test item G are assigned. Since the third reagent of the inspection item G is dispensed at the first reagent discharge position Pb after one round time after the injection, the cleaning position W is moved to the cleaning position W after one round time after the cleaning is performed at the cleaning position W. Stop cleaning when stopped. For this reason, when the reaction containers 17 to which the first and second sets are assigned stop at the cleaning position W, the six reaction containers 17 other than the reaction container 17 at the cleaning position W are cleaned. Therefore, avoid assigning inspection items for 1-reagent system and 2-reagent system.

  Accordingly, the analysis control unit 52 applies to the six reaction vessels 17 adjacent in the R1 direction and the six reaction vessels 17 adjacent in the R2 direction with respect to the reaction vessel 17 to which the sample S7 and the inspection item G are assigned. General items of 1-reagent system and 2-reagent system and samples in which this inspection item is set are not assigned. Further, one reagent system and two for six reaction containers 17 adjacent in the R1 direction and six reaction containers 17 adjacent in the R2 direction with respect to the reaction container 17 to which the sample S8 and the inspection item G are assigned. The general item of the reagent system and the sample set with this inspection item are not assigned.

  FIG. 18 shows the details of each sample to be inspected when not classified into the first and second groups by the fourth specific item and the reagent dispensing operation of each inspection item set in this sample. FIG.

  The sample table 12 holds two sample containers 11. One sample container 11 of the two sample containers 11 stores the sample S 7, and the other sample container 11 stores the sample S 8.

  After the sample S7 and the inspection item G are allotted and the six reaction containers 17 that have been emptied after the cleaning are stopped at the sample discharge position Pa, the sample S7 and the inspection item G are allotted and cleaned. When the reaction container 17 that has been emptied and stopped at the sample discharge position Pa is defined as the first cycle.

  In the first cycle, the sample dispensing probe 19 dispenses the sample S7 in the sample container 11 as the sample S7G for the inspection item G into the reaction container 17 stopped at the sample discharge position Pa.

  In the second cycle, the sample S7 and the inspection item H are allocated, and the reaction container 17 that has been emptied after being cleaned stops at the sample discharge position Pa. The reaction container 17 into which the sample S7G has been dispensed in the first cycle stops at the first reagent discharge position Pb. The sample dispensing probe 19 dispenses the sample S7 in the sample container 11 as the sample S7H for the inspection item H into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1G of the inspection item G of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  The dispensing of the sample S7 is completed by dispensing the sample S7H into the reaction vessel 17 that stops at the sample discharge position Pa in the second cycle.

  In the third cycle, the sample S8 and the inspection item G are assigned, and the reaction container 17 that has been emptied after being cleaned stops at the sample discharge position Pa. The reaction container 17 into which the sample S7H has been dispensed in the second cycle stops at the first reagent discharge position Pb. The sample dispensing probe 19 dispenses the sample SG in the sample container 11 as the sample S8G for the inspection item G into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1H of the inspection item H of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  In the fourth cycle, the sample S8 and the inspection item H are assigned, and the reaction container 17 that has been emptied after being cleaned stops at the sample discharge position Pa. The reaction container 17 into which the sample S8G has been dispensed in the third cycle stops at the first reagent discharge position Pb. The reaction container 17 into which the sample S7G and the first reagent R1G have been dispensed stops at the first stirring position Pc.

  In the fourth cycle, the sample dispensing probe 19 dispenses the sample S8 in the sample container 11 as the sample S8G for the inspection item G into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1G of the inspection item G of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb. The first stirrer 26 stirs the sample S7G and the first reagent R1G in the reaction vessel 17 stopped at the first stirring position Pc.

  With the dispensing of the sample S8H into the reaction vessel 17 stopped at the sample discharge position Pa in the fourth cycle, the dispensing of the sample S8 is completed, and the dispensing of all the samples S7 and S8 to be inspected is completed.

  In the fifth cycle, the reaction container 17 into which the sample S8H has been dispensed in the fourth cycle stops at the first reagent discharge position Pb. The reaction container 17 into which the sample S7H and the first reagent R1H have been dispensed stops at the first stirring position Pc. The first reagent dispensing probe 23 dispenses the first reagent R1H of the inspection item H of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb. The first stirrer 26 stirs the sample S7H and the first reagent R1H in the reaction vessel 17 stopped at the first stirring position Pc.

  By dispensing the first reagent R1H into the reaction container 17 stopped at the first reagent discharge position Pb in the fifth cycle, the first of all the inspection items G, H set in all the samples S7, S8 to be inspected. The dispensing of one reagent is completed.

  In the sixth cycle, the reaction vessel 17 into which the sample S8G and the first reagent R1G have been dispensed stops at the first stirring position Pc. The first stirrer 26 stirs the sample S8G and the first reagent R1G in the reaction vessel 17 stopped at the first stirring position Pc.

  In the seventh cycle, the reaction container 17 into which the sample S8H and the first reagent R1H have been dispensed stops at the first stirring position Pc. The first stirrer 26 stirs the sample S8H and the first reagent R1H in the reaction vessel 17 stopped at the first stirring position Pc.

  The second reagent dispensing probe 30 dispenses the second reagent of the inspection item G to the reaction container 17 that stops at the second reagent discharge position Pf after the sample S7G and the first reagent R1G are stirred in the fourth cycle. Then, after the sample S7H and the first reagent R1H are stirred in the fifth cycle, the second reagent of the inspection item H is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  Further, the second reagent dispensing probe 30 applies the second reagent of the inspection item G to the reaction container 17 that stops at the second reagent discharge position Pf after the sample S8G and the first reagent R1G are stirred in the sixth cycle. After the sample S8H and the first reagent R1H are stirred in the seventh cycle, the second reagent of the inspection item H is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  The third stirrer 33 stirs the sample S7G, the first reagent R1G, and the second reagent of the test item G in the reaction container 17 that stops at the third stirring position Pg, and stops at the third stirring position Pg. The sample S7H, the first reagent R1H, and the second reagent of the inspection item H are stirred. The third stirrer 33 stirs the sample S8G, the first reagent R1G, and the second reagent of the inspection item G in the reaction vessel 17 that stops at the third stirring position Pg, and stops at the third stirring position Pg. The sample S8H, the first reagent R1H, and the second reagent of the inspection item H in the container 17 are agitated.

  The cleaning nozzle 36 stops cleaning when the reaction container 17 containing the sample S7G, the first reagent R1G, and the second reagent of the inspection item G stops at the cleaning position W, and the sample S7H, the first reagent R1H, and the inspection item Washing is performed when the reaction container 17 containing the second reagent of H stops at the washing position W.

  The cleaning nozzle 36 stops cleaning when the reaction container 17 containing the sample S8G, the first reagent R1G, and the second reagent of the test item G stops at the cleaning position W, and the sample S8H, the first reagent R1H, Cleaning is performed when the reaction container 17 containing the second reagent of the inspection item H stops at the cleaning position W.

  Of the reaction containers 17 stopped at the first reagent discharge position Pb, the first reagent dispensing probe 23 is placed in the first reagent container in the reaction container 17 containing the sample S7G, the first reagent R1G, and the second reagent of the test item G. The third reagent of the 13 inspection items G is dispensed, and the third reagent of the inspection item G of the first reagent container 13 is placed in the reaction container 17 containing the sample S8G, the first reagent R1G, and the second reagent of the inspection item G. Dispense.

  The first stirrer 26 stirs the sample S7G, the first reagent R1G, the second reagent and the third reagent of the inspection item G in the reaction vessel 17 stopped at the first stirring position Pc, and stops at the first stirring position Pc. The sample S8G, the first reagent R1G, the second reagent and the third reagent of the inspection item G in the reaction container 17 are stirred.

  The cleaning nozzle 36 performs cleaning when the reaction container 17 containing the mixed liquid of the sample S7G, the first reagent R1G, the second reagent of the inspection item G, and the third reagent that have been measured stops at the cleaning position W. In addition, the cleaning nozzle 36 performs cleaning when the reaction container 17 containing the mixed liquid of the sample S8G, the first reagent R1G, the second reagent of the inspection item G, and the third reagent that have been measured stops at the cleaning position W. .

  In the fourth cycle, the analysis control unit 52 dispenses the first reagent R1G, and cleans the reaction container 17 that contains the mixed solution of the sample S8G, the first reagent R1G, the second reagent of the inspection item G, and the third reagent. When the process ends, the analysis operation of the analysis unit 10 is terminated.

  FIG. 19 is a diagram showing the positions of the reaction vessels 17 to which the samples S7 and S8 and the inspection items G and H are assigned when classified into the first and second groups by the fourth specific item. is there.

  The analysis control unit 52 assigns the sample S7 and the inspection item G to one reaction container 17 to be cleaned at the cleaning position W, and the cleaning is performed one cycle time after the reaction container 17 stops at the cleaning position W. The sample S8 and the inspection item G are assigned to one reaction vessel 17 that stops at the position W and is cleaned.

  In addition, the analysis control unit 52 stops the reaction vessel 17 to which the sample S8 and the inspection item G are assigned at the washing position W and stops at the washing position W one cycle after the reaction vessel 17 is cleaned. The sample S7 and the inspection item H are assigned to the sample, and the sample for one reaction vessel 17 in which the reaction vessel 17 stops at the washing position W and is washed after one cycle time after the reaction vessel 17 stops at the washing position W. S8 and inspection item H are assigned.

  When the reaction container 17 to which the sample S7 and the inspection item G are assigned stops at the sample discharge position Pa, the reaction container 17 to which the sample S8 and the inspection item G are assigned is the position of the reaction container 17 to which the sample S7 and the inspection item G are assigned. Is stopped at the other end position where the center angle θ is one end position of the arc, and the reaction vessel 17 to which the sample S7 and the inspection item H are assigned stops at the seventh washing position W7, and the sample S8 and the inspection item H are assigned to it. The reaction vessel 17 stops at the other end position where the seventh washing position W7 is the one end position of the arc having the central angle θ.

  Then, the analysis control unit 52 dispenses the first reagent of the inspection item G at the first reagent discharge position Pb to the reaction container 17 to which the sample S7 and the inspection item G and the sample S8 and the inspection item G are assigned. Since the third reagent of the test item G is dispensed at the first reagent discharge position Pb after one round time, the cleaning is stopped at the cleaning position W after one round time after the cleaning is performed at the cleaning position W. Stop cleaning. Therefore, when the sample S7 and the inspection item G and the sample S8 and the inspection item G are stopped at the cleaning position W, the six reaction containers 17 other than the reaction container 17 at the cleaning position W are cleaned. Avoid assigning general items for 1-reagent and 2-reagent systems because they cannot be performed.

  Accordingly, the analysis control unit 52 applies to the six reaction vessels 17 adjacent in the R1 direction and the six reaction vessels 17 adjacent in the R2 direction with respect to the reaction vessel 17 to which the sample S7 and the inspection item G are assigned. General items of 1-reagent system and 2-reagent system and samples in which this inspection item is set are not assigned. Further, one reagent system and two for six reaction containers 17 adjacent in the R1 direction and six reaction containers 17 adjacent in the R2 direction with respect to the reaction container 17 to which the sample S8 and the inspection item G are assigned. The general item of the reagent system and the sample set with this inspection item are not assigned.

  FIG. 20 shows the details of each sample to be inspected when classified into the first and second groups by the fourth specific item, and the dispensing operation of the reagent for each inspection item set in this sample. FIG.

  Six unreacted reaction containers 17 that have been emptied after being stopped are respectively stopped at the sample discharge position Pa, then the sample S7 and the inspection item G are allocated, and the reaction containers that have been emptied after being cleaned. The time when 17 stops at the sample discharge position Pa is defined as the first cycle.

  In the first cycle, the sample dispensing probe 19 dispenses the sample S7 in the sample container 11 as the sample S7G for the inspection item G into the reaction container 17 stopped at the sample discharge position Pa.

  In the second cycle, the sample S8 and the inspection item G are assigned, and the reaction container 17 that has been emptied after being cleaned stops at the sample discharge position Pa. The reaction container 17 into which the sample S7G has been dispensed in the first cycle stops at the first reagent discharge position Pb. The sample dispensing probe 19 dispenses the sample S8 in the sample container 11 as the sample S8G for the inspection item G into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1G of the inspection item G of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  In the third cycle, the sample S7 and the inspection item H are assigned, and the reaction container 17 that has been emptied after being cleaned stops at the sample discharge position Pa. The reaction container 17 into which the sample S8G has been dispensed in the second cycle stops at the first reagent discharge position Pb. The sample dispensing probe 19 dispenses the sample S7 in the sample container 11 as the sample S7H for the inspection item H into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1G of the inspection item G of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb.

  With the first reagent R1G being dispensed into the reaction vessel 17 stopped at the first reagent discharge position Pb in the third cycle, the dispensing of the first reagent of each set of inspection items G classified into the first group is finish.

  In the fourth cycle, the sample S8 and the inspection item H are assigned, and the reaction container 17 that has been emptied after being cleaned stops at the sample discharge position Pa. The reaction container 17 into which the sample S7H has been dispensed in the third cycle stops at the first reagent discharge position Pb. The reaction container 17 into which the sample S7G and the first reagent R1G have been dispensed stops at the first stirring position Pc.

  In the fourth cycle, the sample dispensing probe 19 dispenses the sample S8 in the sample container 11 as the sample S8H for the inspection item H into the reaction container 17 stopped at the sample discharge position Pa. The first reagent dispensing probe 23 dispenses the first reagent R1H of the inspection item H of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb. The first stirrer 26 stirs the sample S7G and the first reagent R1G in the reaction vessel 17 stopped at the first stirring position Pc.

  The dispensing of all the samples S7 and S8 to be inspected is completed by dispensing the sample S8H to the reaction container 17 that stops at the sample discharge position Pa in the fourth cycle.

  In the fifth cycle, the reaction container 17 into which the sample S8H has been dispensed in the fourth cycle stops at the first reagent discharge position Pb. The reaction container 17 into which the sample S8G and the first reagent R1G have been dispensed stops at the first stirring position Pc. The first reagent dispensing probe 23 dispenses the first reagent R1H of the inspection item H of the first reagent container 13 into the reaction container 17 stopped at the first reagent discharge position Pb. The first stirrer 26 stirs the sample S8G and the first reagent R1G in the reaction vessel 17 stopped at the first stirring position Pc.

  Dispensing the first reagent of each set of inspection items H classified into the second group by dispensing the first reagent R1H into the reaction container 17 stopped at the first reagent discharge position Pb in the fifth cycle is as follows. finish.

  In the sixth cycle, the reaction container 17 into which the sample S7H and the first reagent R1H have been dispensed stops at the first stirring position Pc. The first stirrer 26 stirs the sample S7H and the first reagent R1H in the reaction vessel 17 stopped at the first stirring position Pc.

  In the seventh cycle, the reaction container 17 into which the sample S8H and the first reagent R1H have been dispensed stops at the first stirring position Pc. The first stirrer 26 stirs the sample S8H and the first reagent R1H in the reaction vessel 17 stopped at the first stirring position Pc.

  The second reagent dispensing probe 30 dispenses the second reagent of the inspection item G to the reaction container 17 that stops at the second reagent discharge position Pf after the sample S7G and the first reagent R1G are stirred in the fourth cycle. Then, after the sample S8G and the first reagent R1G are agitated in the fifth cycle, the second reagent of the inspection item G is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  Further, the second reagent dispensing probe 30 applies the second reagent of the inspection item H to the reaction container 17 that stops at the second reagent discharge position Pf after the sample S7H and the first reagent R1H are stirred in the sixth cycle. After the sample S8H and the first reagent R1H are stirred in the seventh cycle, the second reagent of the inspection item H is dispensed into the reaction container 17 that stops at the second reagent discharge position Pf.

  The third stirring bar 33 stirs the sample S7G, the first reagent R1G, and the second reagent of the inspection item G in the reaction container 17 stopped at the third stirring position Pg, and the reaction container 17 stopped at the third stirring position Pg. The sample S8G, the first reagent R1G, and the second reagent of the inspection item G are stirred. The third stirrer 33 stirs the sample S7H, the first reagent R1H, and the second reagent of the inspection item H in the reaction vessel 17 stopped at the third stirring position Pg, and stops the reaction at the third stirring position Pg. The sample S8H, the first reagent R1H, and the second reagent of the inspection item H in the container 17 are agitated.

  The cleaning nozzle 36 stops the cleaning when the reaction container 17 containing the sample S7G, the first reagent R1G, and the second reagent of the inspection item G stops at the cleaning position W, and the sample S8G, the first reagent R1G, and the inspection item When the reaction container 17 containing the second reagent G stops at the cleaning position W, the cleaning is stopped.

  The cleaning nozzle 36 performs cleaning when the reaction container 17 containing the sample S7H, the first reagent R1H, and the second reagent of the inspection item H stops at the cleaning position W, and performs the sample S8H, the first reagent R1H, and the inspection. Washing is performed when the reaction container 17 containing the second reagent of item H stops at the washing position W.

  Of the reaction containers 17 stopped at the first reagent discharge position Pb, the first reagent dispensing probe 23 is placed in the first reagent container in the reaction container 17 containing the sample S7G, the first reagent R1G, and the second reagent of the test item G. The third reagent of the 13 inspection items G is dispensed, and the third reagent of the inspection item G of the first reagent container 13 is placed in the reaction container 17 containing the sample S8G, the first reagent R1G, and the second reagent of the inspection item G. Dispense.

  The first stirrer 26 stirs the sample S7G, the first reagent R1G, the second reagent and the third reagent of the inspection item G in the reaction vessel 17 stopped at the first stirring position Pc, and stops at the first stirring position Pc. The sample S8G, the first reagent R1G, the second reagent and the third reagent of the inspection item G in the reaction container 17 are stirred.

  The cleaning nozzle 36 performs cleaning when the reaction container 17 containing the sample S7G, the first reagent R1G, the second reagent of the test item G, and the mixed solution of the third reagent stopped at the cleaning position W. In addition, the cleaning nozzle 36 performs cleaning when the reaction container 17 containing the mixed solution of the sample S8G, the first reagent R1G, the second reagent of the inspection item G, and the third reagent that have been measured stops at the cleaning position W. Do.

  The analysis control unit 52 dispenses the first reagent R1G in the third cycle, and cleans the reaction container 17 that contains the mixed solution of the sample S8G, the first reagent R1G, the second reagent of the inspection item G, and the third reagent. When the process ends, the analysis operation of the analysis unit 10 is terminated.

  In this way, the first reagent R1G is dispensed in the fourth cycle to the reaction vessel 17 that is finally cleaned unless it is classified into the first and second groups, and is classified into the first and second groups. Since the first reagent R1G is dispensed in the third cycle with respect to the reaction vessel 17 that is finally washed, the analysis unit is earlier by one cycle time by classifying it into the first and second groups. Ten analysis operations can be terminated. Thereby, inspection time can be shortened.

  According to the embodiment described above, if there are two or more samples in which a specific item is set among a plurality of samples to be inspected and one or more samples in which general items are set, A first group consisting of at least a first and a second set each set of a sample and a specific item set for this sample, each sample to be inspected, and a general item set for this sample are set to 1 The first group or the second group is preferentially assigned to each reaction vessel 17 that is classified into at least a third group that is a set, and is cleaned by the cleaning nozzle 36. After that, each set of the other group is assigned, and each reaction vessel 17 assigned with priority is made to dispense the reagent of each set of test items of one group, and the reagent of each set of test items of one group is dispensed. After the note ends, each pair of the other group Ri reagent of the set of test items in each reaction vessel 17 was applied can be dispensed minute. Thereby, inspection time can be shortened.

  Although several embodiments of the present invention have been described, these embodiments are presented by way of example and are not intended to limit the scope of the invention. These novel embodiments can be implemented in various other forms, and various omissions, replacements, and changes can be made without departing from the scope of the invention. These embodiments and modifications thereof are included in the scope and gist of the invention, and are included in the invention described in the claims and the equivalents thereof.

DESCRIPTION OF SYMBOLS 10 Analysis part 17 Reaction container 19 Sample dispensing probe 23 1st reagent dispensing probe 36 Washing nozzle 50 Drive part 51 Classification | category part 52 Analysis control part

Claims (6)

If there are two or more samples in which a specific inspection item is set among a plurality of samples to be inspected and one or more samples in which general inspection items other than the specific inspection item are set, 1 Of the two or more sets, each including one specific test item and one sample in which the test item is set, at least a first group including the first set and the second set, and one A classification unit that classifies the general inspection item and a second group including at least a third set of one sample in which the inspection item is set;
The reagent of all the test items of the set belonging to either one of the first group or the second group classified by the classification unit is first dispensed, and the test item of the set belonging to the other group And an automatic analyzer comprising a controller for dispensing later reagents.   In the case where there is one or no sample in which the specific inspection item is set among the plurality of samples to be inspected, the control unit, in the order set in advance for the plurality of samples to be inspected. The automatic analyzer according to claim 1, wherein the sample is dispensed based on the sample. The reaction container in which the sample and the reagent are dispensed is moved in one direction every cycle time, and the cleaning position is at each stop position including a cleaning position, a sample discharge position, a reagent discharge position, and a sample suction / discharge position. A drive unit that stops the sample discharge position, the reagent discharge position, and the sample suction / discharge position in this order,
The cleaning nozzle cleans the reaction vessel stopped at the cleaning position,
The controller is
One reaction vessel that stops at the washing position and is washed is used for preparation, and the reaction vessel stops at the washing position after two cycle times after the reaction vessel stops at the washing position. Assigning the first set to two reaction vessels for measuring one reaction vessel;
One reaction vessel that is stopped at the washing position after one cycle time after the reaction vessel for preparation assigned to the first set is stopped at the washing position and is washed is used for preparation. Two reaction vessels for measurement, one reaction vessel that stops at the washing position after one cycle time and is washed after the measurement reaction vessel assigned to the set is stopped at the washing position Assign the second set to
A reaction vessel that stops at the washing position and performs washing one cycle time before the reaction vessel for preparation to which the first set is assigned stops at the washing position, or for measurement to which the second set is assigned Assigning the third set to a reaction vessel in which the reaction vessel is stopped at the washing position one cycle after the reaction vessel is stopped at the washing position and cleaned.
The sample dispensing probe dispenses the first set of samples into the reaction container for preparation to which the first set is allocated among the reaction containers stopped at the sample discharge position, and the second set. Dispensing the second set of samples into a preparative reaction vessel assigned to, and dispensing the third set of samples into a reaction vessel assigned to the third set;
The reagent dispensing probe dispenses a diluent into the reaction container for preparation containing the first set of samples dispensed at the sample ejection position among the reaction containers stopped at the reagent ejection position. , The dilution liquid is dispensed into the reaction vessel for preparation containing the second set of samples dispensed at the sample discharge position, and the third set of liquid dispensed at the sample discharge position Dispensing the reagent of the third set of general test items into a reaction container containing the sample,
The sample dispensing probe includes the sample diluted with the diluted sample in the reaction vessel that contains the diluted sample obtained by diluting the first set of samples with the diluent, among the reaction vessels stopped at the sample suction / discharge position. The diluted sample in the reaction container that contains the diluted sample in which the first set of samples stopped at the discharge position is dispensed to the measurement reaction vessel assigned and the second set of samples is diluted with the diluent. To the reaction vessel for measurement assigned to the second set stopped at the sample discharge position,
The reagent dispensing probe has a specific test item of the first set in a reaction container for measurement to which the first set for storing the diluted sample is allocated among the reaction containers stopped at the reagent discharge position. The reagent of the said 2nd set of specific test | inspection items is dispensed to the reaction container for a measurement to which the said 2nd set which accommodates the said diluted sample is dispensed. 2. The automatic analyzer according to 2. The reaction container into which the sample and the reagent are dispensed is moved in one direction, and the cleaning position, the sample discharge position, at each stop position including the cleaning position, the sample discharge position, the reagent discharge position, and the sample suction / discharge position. A drive unit that stops the reagent discharge position and the sample suction / discharge position in this order,
The cleaning nozzle cleans the reaction vessel stopped at the cleaning position,
The controller is
Assigning the first set to one reaction vessel that stops at the washing position and is washed;
Assigning the second set to one reaction vessel in which the reaction vessel assigned with the first set stops at the washing position and then stops at the washing position and is washed;
The reaction vessel assigned to the first set stops before the washing position and stops at the washing position, and the reaction vessel assigned with the second set stops at the washing position. And assigning the third set to a reaction vessel that is stopped at the washing position and washed.
The sample dispensing probe dispenses the third set of samples into a reaction vessel assigned with the third set among the reaction vessels stopped at the sample discharge position,
The reagent dispensing probe dispenses the reagent of the specific test item of the first group into an empty reaction container to which the first group is allocated among the reaction containers stopped at the reagent discharge position, A reaction in which the reagent of the specific test item of the second set is dispensed into an empty reaction container to which the second set is assigned, and the third set of samples dispensed at the sample discharge position is accommodated. Dispensing the reagent of the third set of general test items into a container;
The sample dispensing probe accommodates the first container in the reaction container containing the reagent of the first test item dispensed at the reagent discharge position among the reaction containers stopped at the sample suction / discharge position. A sample of one set is dispensed, and the second set of samples is dispensed into a reaction container that accommodates the reagent of the second set of specific test items dispensed at the reagent discharge position. The automatic analyzer according to claim 1 or 2. The reaction container into which the sample and the reagent are dispensed is moved in one direction, and at each stop position including the cleaning position, the sample discharge position, and the reagent discharge position, the cleaning position, the sample discharge position, and the reagent discharge position are A drive unit that stops in order,
The specific test item is a test item that affects the preset test item and the test item that is affected by the test item.
In the classification unit, the test item that affects the test item and the test item that is affected are set, and the next dispensing of the reagent of the test item that affects the test item is the reagent item of the test item that is affected. When there are two samples set to be dispensed, the first group consisting of the first set and the second set, and the affected inspection item as the general inspection item Classify into the second group consisting of a third set and a fourth set;
The cleaning nozzle cleans the reaction vessel stopped at the cleaning position,
When the control unit causes the reagent of the general test item of each set of the second group to be dispensed after the dispensing of the reagent of the specific test item of the set of the first group is completed, The first set is assigned to one reaction container to be cleaned by the cleaning nozzle, and one reaction in which the reaction container stops at the cleaning position and then stops at the cleaning position to perform cleaning. Assigning the second set to a container, and for each reaction container that stops at the cleaning position and is cleaned after the reaction container stops at the cleaning position, Assigning the third set to one reaction vessel in which the reaction vessel is stopped at the washing position and then washed at the washing position after the reaction vessel is stopped at the washing position; The reaction vessel is stopped at the washing position. Allocating the fourth set for one reaction vessel cleaning is performed by stopping the cleaning position the later,
The sample dispensing probe dispenses the first set of samples to the reaction container to which the first set is assigned among the reaction containers stopped at the sample discharge position, and the second set is assigned to the sample dispensing probe. The second set of samples is dispensed into the reaction vessel, the third set of samples is dispensed into the reaction vessel assigned with the third set, and the fourth set is assigned to the reaction vessel. Dispensing the fourth set of samples into a container;
Reagent dispensing probe
Among the reaction containers stopped at the reagent discharge position, the reagent of the specific test item of the first set is dispensed into the reaction container that stores the first set of samples dispensed at the sample discharge position. , The reagent of the second set of specific test items is dispensed into a reaction container containing the second set of samples dispensed at the sample ejection position, and the dispensed at the sample ejection position A reaction container containing the fourth set of samples dispensed at the sample discharge position by dispensing the reagent of the third set of general inspection items into a reaction container containing the third set of samples. Dispensing reagents for the fourth set of general test items to
The apparatus according to claim 1 or 2, wherein when the unassigned empty reaction container stops at the reagent discharge position, the cleaning liquid stored in the predetermined container is sucked and discharged at a place other than the predetermined container. The automatic analyzer according to claim 2. Each of the reaction containers to which the sample and the reagent are dispensed is moved in one direction every cycle time and includes at least a cleaning position including a first cleaning position and a second cleaning position, a sample discharge position, and a reagent discharge position. At the stop position, the first cleaning position, the second cleaning position, the sample discharge position, and the reagent discharge position are stopped in this order, and one round time before the one round time has elapsed before the first cycle time. A drive unit for stopping at the stopped position,
A measurement unit for measuring a mixed solution of the sample and the reagent in the reaction container;
A reagent dispensing probe for dispensing the reagent into the reaction container stopped at the reagent discharge position;
The reagent of the specific test item consists of first and second reagents dispensed into the reaction container stopped at the reagent discharge position by the reagent dispensing probe,
The washing nozzle is used to wash the reaction vessel in which the sample is dispensed among the reaction vessels stopped at the washing position or the reaction vessel containing the mixed solution that has been measured by the measurement unit,
The controller is
The first set is assigned to one reaction container to be cleaned by the cleaning nozzle, and one reaction in which the reaction container stops at the cleaning position and then stops at the cleaning position to perform cleaning. Assigning said second set to a container;
A reaction vessel in which the reaction vessel assigned with the first set stops at one of the first or second washing positions and is washed at the other washing position; and the second When the reaction vessel to which the set is assigned stops at one of the first or second cleaning positions, the third set is set against the reaction vessel that stops at the other cleaning position and performs cleaning. Unassigned and unassigned reaction vessels,
The third set is assigned to the reaction containers in which the first and second sets of reaction vessels and the unassigned reaction vessels are stopped at the washing position and then washed at the washing position. ,
The sample dispensing probe dispenses the first set of samples to the reaction container to which the first set is assigned among the reaction containers stopped at the sample discharge position, and the second set is assigned to the sample dispensing probe. Dispensing the second set of samples into the reaction vessel, dispensing the third set of samples into the reaction vessel to which the third set is assigned,
The reagent dispensing probe dispenses the first reagent into a reaction container containing the first set of samples dispensed at the sample ejection position among the opposite containers stopped at the reagent ejection position. Then, the first reagent is dispensed into a reaction container that accommodates the second set of samples dispensed at the sample discharge position, and the third set of samples dispensed at the sample discharge position. Dispensing the reagents of the third set of general test items into a reaction container containing
The washing nozzle is configured to stop the reaction container containing the first set of samples and the first reagent or the reaction container containing the second set of samples and the first reagent at the washing position. And when the reaction container containing the third set of samples and reagents stops at the washing position, washing is performed,
The reagent dispensing probe dispenses the second reagent into a reaction container containing the first set of samples and the first reagent among the reaction containers stopped at the reagent discharge position, The automatic analyzer according to claim 1 or 2, wherein the second reagent is dispensed into a reaction container containing two sets of samples and the first reagent.