JP2010127868A - Analyzer and its reaction vessel cleaning method - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an analyzer and its reaction vessel cleaning method capable of changing a cleaning level of the reaction vessel corresponding to the height of analysis sensitivity. <P>SOLUTION: The automatic analyzer 1 includes a cleaning device for cleaning the reaction vessels after analyzing a reaction liquid, after reacting a liquid sample including a specimen and a reagent in a plurality of reaction vessels 6 held on a cuvette wheel 5. The reaction vessel cleaning method thereof is also provided. The plurality of reaction vessels 6 are arranged on upper and lower two stages on the cuvette wheel 5, and the automatic analyzer 1 also includes replacing parts 17, 21 for rotating and replacing two reaction vessels on the upper and lower two stages in the vertical direction as a pair on at least two spots near the cuvette wheel. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  The present invention relates to an analyzer and a reaction container cleaning method.

  Conventionally, automatic analyzers analyze specimens consisting of biological components such as blood and urine, react the specimens and reagents in a reaction vessel, and measure the optical properties of the reaction liquid to measure specific components in the specimen The content of etc. is measured. The automatic analyzer reuses the reaction container after washing with a washing device (see, for example, Patent Document 1).

JP 2008-128662 A

  By the way, in recent years, an analysis apparatus having a function of analyzing an inspection item having a low analysis sensitivity and an inspection item having a high analysis sensitivity has been provided. An analyzer equipped with such a combined function can, for example, clean a reaction vessel used for a genetic test item having a high analytical sensitivity by performing cleaning for a conventional biochemical test item having a low analytical sensitivity. In some cases, it was insufficient to avoid the problem.

  The present invention has been made in view of the above, and an object of the present invention is to provide an analyzer capable of changing the cleaning level of a reaction vessel in accordance with the level of analysis sensitivity and a method for cleaning the reaction vessel. .

  In order to solve the above-described problems and achieve the object, the analyzer of the present invention reacts a liquid sample containing a specimen and a reagent in a plurality of reaction vessels held on a cuvette wheel, and analyzes the reaction solution. The plurality of reaction vessels are arranged in two upper and lower stages on the cuvette wheel, and the two upper and lower two stages are arranged at least at two locations near the cuvette wheel. It is characterized by comprising a replacement means for rotating one reaction vessel as a set and rotating it up and down.

  Further, the analysis apparatus of the present invention is characterized in that, in the above-mentioned invention, an attaching means for covering the upper reaction vessel with a lid and a removing means for removing the covered lid from the reaction vessel. .

  In the analyzer according to the present invention, the two reaction vessels in the upper and lower stages are arranged so that the respective openings are directed upward and downward between the two support plates rotating around the central axis. It is fixed.

  In the analyzer according to the present invention, the two reaction vessels in the upper and lower stages swing between the two support plates rotating around the central axis so that the respective openings are directed upward. It is characterized by being freely supported.

  Moreover, the analyzer according to the present invention is characterized in that, in the above invention, the cleaning devices are arranged on both upper and lower sides of the upper reaction vessel side and the lower reaction vessel side of the cuvette wheel.

  In order to solve the above-described problems and achieve the object, the method for washing a reaction container of the analyzer of the present invention is to react the specimen and a reagent in the reaction container and optically measure the reaction liquid, thereby And a reaction container cleaning method of an analyzer for cleaning the reaction container after the completion of photometry, which is different from a normal cleaning process for cleaning the reaction container and a transport path of the reaction container for analyzing a sample. And a special cleaning step of transporting along the transport path and specially cleaning the reaction vessel.

  In the analyzer of the present invention, a plurality of reaction containers are arranged in two stages on the cuvette wheel, and the two reaction containers of two stages on the upper and lower sides are rotated as a set at least at two locations in the vicinity of the cuvette wheel. The reaction container cleaning method of the analyzer of the present invention includes a normal cleaning process for cleaning the reaction container, a transport path for the reaction container for analyzing the sample, and a transport path that is different from the transport path. And a special washing step for washing, so that the washing level of the reaction vessel can be changed according to the level of analysis sensitivity.

  DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, embodiments of an analyzer according to the present invention will be described in detail with reference to the drawings. FIG. 1 is a schematic configuration diagram showing an automatic analyzer of the present invention. FIG. 2 is a cross-sectional view of the cuvette wheel of the analyzer of FIG. 1 cut along the circumferential direction at the cleaning section.

  As shown in FIG. 1, the automatic analyzer 1 includes a first reagent table 2, a second reagent table 3, a cuvette wheel 5, a first reagent dispensing device 7, a second reagent dispensing device 9, and a sample container transfer unit 11. , A stirring unit 13, a photometric unit 14, a cleaning unit 15, a cap attaching unit 16, a lower stage moving replacement unit 17, a cap removal part 20, an upper stage moving replacement unit 21, and a control unit 25. Here, the cap attaching part 16, the lower stage moving replacement part 17, the cap removal part 20 and the upper stage moving replacement part 21 are used when the reaction vessel is specially cleaned.

  Since the first reagent table 2 and the second reagent table 3 have the same structure, the first reagent table 2 will be described. For the second reagent table 3, reference numerals corresponding to corresponding components are used.

  As shown in FIG. 1, the first reagent table 2 is a reagent table that holds a plurality of reagent containers 2 a of the first reagent, and is rotated by a driving unit to convey the plurality of reagent containers 2 a in the circumferential direction. At this time, the first reagent table 2 has the first reading unit 2c arranged on the outer periphery. The first reading unit 2c reads information on an information recording medium such as a barcode label attached to the plurality of reagent containers 2a.

  As shown in FIG. 1, the cuvette wheel 5 has a plurality of reaction vessels 6 arranged in the circumferential direction, and is rotated forward or reverse by drive means different from the drive means of the reagent tables 2 and 3 to move the reaction vessel 6 Transport. The cuvette wheel 5 rotates, for example, clockwise (1 turn-1 reaction vessel) / 4 in one cycle and counterclockwise (1 turn-1 reaction vessel) in four cycles. At this time, as shown in FIG. 2, the cuvette wheel 5 has a plurality of reaction vessels 6 arranged in two upper and lower stages.

  The reaction vessel 6 is a cuvette with a small volume of a square tube shape of several nL to several tens of μL, and a transparent material that transmits 80% or more of the analysis light emitted from the photometry unit 14, for example, glass containing heat-resistant glass, Synthetic resins such as cyclic olefins and polystyrene are used. The reaction container 6 is supplied from the reagent containers 2a and 3a of the first reagent table 2 and the second reagent table 3 by the first reagent dispensing device 7 and the second reagent dispensing device 9 provided in the vicinity of the cuvette wheel 5. And the second reagent is dispensed. As shown in FIG. 3, the reaction vessel 6 is fixed between two support plates P having a central axis A with the respective openings 6a facing upward and downward, and is attached to the cuvette wheel 5 via the central axis A. It is attached. At this time, the two reaction vessels 6 fixed between the support plates P are driven by the upper stage movement replacement unit 21 or the lower stage movement replacement unit 17 to rotate around the central axis A, and the upper side or lower side of the cuvette wheel 5. To be replaced.

  On the other hand, since the first reagent dispensing device 7 and the second reagent dispensing device 9 have the same structure, the first reagent dispensing device 7 will be described, and the second reagent dispensing device 9 will correspond. The code | symbol corresponding to a component is used.

  The first reagent dispensing device 7 is a dedicated dispensing device for dispensing the first reagent. As shown in FIG. 1, the first reagent dispensing device 7 is rotated in the direction of the arrow in the horizontal plane and is moved up and down in the vertical direction. 7a and a probe 7b that is supported by the arm 7a and dispenses a reagent, and a washing tank 8 for washing the probe 7b is disposed on the movement locus of the probe 7b. The cleaning tank 8 discards the cleaning water discharged from the probe 7b and cleaned the inside of the probe 7b, and cleans the outside of the probe 7b with the cleaning water jetted into the tank.

  As shown in FIG. 1, the sample container transfer unit 11 is a transfer unit that transfers a plurality of racks 11 a along the direction of the arrow, and transfers the racks 11 a while stepping. The rack 11a holds a plurality of sample containers 11b containing samples. Here, in the sample container 11b, the sample is dispensed into each reaction container 6 by the sample dispensing device 12.

  The sample dispensing device 12 is a device dedicated to sample dispensing that dispenses a sample to the reaction container 6 every time the step of the rack 11a transferred by the sample container transfer unit 11 stops, and rotates in the horizontal direction. In addition, it has a drive arm 12a that moves up and down in the vertical direction and a probe 12b supported by the drive arm 12a. For this reason, the specimen dispensing apparatus 12 has a cleaning tank that cleans the probe 12b with cleaning water.

  As shown in FIG. 1, the agitating unit 13 is disposed in the vicinity of the second reagent dispensing device 9 on the outer periphery of the cuvette wheel 5 and agitates a liquid sample containing the specimen and the reagent dispensed in the reaction container 6. As the stirring unit 13, for example, a stirring device that stirs a liquid sample in a non-contact manner using a surface acoustic wave element or a stirring device that stirs a liquid sample using a stirring rod is used.

  As shown in FIG. 1, the photometric unit 14 is disposed between the stirring unit 13 and the cleaning unit 15 on the outer periphery of the cuvette wheel 5, and analyzes the reaction solution in the reaction vessel 6 in which the reagent and the sample have reacted. The analysis light is emitted. The photometry unit 14 outputs an optical signal related to the amount of analysis light that has passed through the reaction liquid in the reaction vessel 6 to the control unit 25.

  As shown in FIG. 1, the cleaning unit 15 is disposed in the vicinity of the sample dispensing device 12 on the upper side of the cuvette wheel 5, and cleans the reaction container 6 in which photometry has been completed by dispensing diluted detergent. As shown in FIG. 2, the cleaning unit 15 includes two pairs of detergent nozzles 15A and 15B, three pairs of cleaning nozzles 15C to 15E, a suction nozzle 15F, and an air nozzle 15G, which are integrated with the holding member 15H. And move up and down as indicated by the arrows.

  As shown in FIG. 2, the detergent nozzle pair 15A, 15B is inserted to the bottom of the discharge nozzle 15a for discharging the diluted detergent into the reaction container 6 and longer than the discharge nozzle 15a, and sucks the liquid in the reaction container 6. And the inside of the reaction vessel 6 is washed with a diluted detergent. The cleaning nozzle pairs 15C to 15E have the same configuration. For example, the cleaning nozzle pair 15C includes a discharge nozzle 15a that discharges cleaning water to the reaction container 6, and a suction nozzle 15b that sucks cleaning water in the reaction container 6. The reaction vessel 6 is rinsed and washed with washing water. The suction nozzle 15F has a suction nozzle 15b that sucks the washing water in the reaction vessel 6, and sucks the washing water in the reaction vessel 6 after the rinsing washing. The air nozzle 15G discharges dry air and dries the reaction container 6 after the rinse cleaning.

  As shown in FIGS. 1 and 2, the cap adherent portion 16 is disposed on one side of the cleaning portion 15 in the vicinity of the cuvette wheel 5, and the sealing cap C (see FIG. 5)). As shown in FIG. 3, the cap attaching part 16 includes a chuck device 16a having a chuck claw for sandwiching the sealing cap C, an arm member 16b that expands and contracts while supporting the chuck device 16a, and moves the arm member 16b up and down. And a lifting device 16c.

  The lower stage moving replacement unit 17 is a replacement unit that replaces the two upper and lower two reaction vessels 6 by rotating them vertically as a set, and is adjacent to the cap attaching unit 16 as shown in FIGS. The actuator 18 and the lifting device 19 are provided.

  The actuator 18 is disposed inside the cuvette wheel 5, and the lower part of the lower reaction container 6 at the opposite position of the two reaction containers 6 fixed between the support plates P is disposed radially outward of the cuvette wheel 5. The two reaction vessels 6 are rotated together with the support plate P around the central axis A in the vertical direction in cooperation with the lifting device 19. As such an actuator 18, for example, a cylinder using air pressure or hydraulic pressure can be used.

  The elevating device 19 has an extendable arm 19b that is supported on the column 19a so as to be movable up and down. The lifting device 19 moves the two reaction vessels 6 together with the support plate P while raising the telescopic arm 19b while supporting the side surface of the lower reaction vessel 6 pushed outward in the radial direction of the cuvette wheel 5 by the telescopic arm 19b. As shown in Fig. 8, the telescopic arm 19b is extended in the vertical direction and finally the side surface of the reaction vessel 6 is pressed inward in the radial direction of the cuvette wheel 5. As a result, the lower stage movement replacement unit 17 moves the upper reaction container 6 with the cap attaching part 16 covered with the sealing cap C to the lower stage and replaces it with the lower reaction container 6.

  As shown in FIG. 1, the cap removal part 20 is arranged on the opposite side of the cap attaching part 16 with the cleaning part 15 in the vicinity of the cuvette wheel 5 interposed therebetween, and is sealed from the reaction vessel 6 positioned on the upper stage of the cuvette wheel 5. It is a removing means for removing the cap C (see FIG. 5). Since the cap removing part 20 has the same configuration as the cap attaching part 16, reference numerals corresponding to corresponding parts are given.

  The upper stage moving replacement unit 21 is an upper stage moving replacement unit that replaces the reaction vessel 6 positioned at the lower stage of the cuvette wheel 5 with the upper reaction container 6, and sandwiches the cleaning unit 15 in the vicinity of the cuvette wheel 5 as shown in FIG. Is arranged on the opposite side of the lower stage moving replacement unit 17. The upper stage movement replacement unit 21 includes an actuator 22 and a lifting device 23 having the same configuration as the lower stage movement replacement unit 17.

  The control unit 25 is, for example, a microcomputer and is connected to the automatic analyzer 1 as shown in FIG. 1, controls the operation of each component of the automatic analyzer 1, and outputs the light output from the photometric unit 14. Analyze the component concentration of the sample from the absorbance of the reaction solution based on the signal. In addition, the control unit 25 executes the analysis operation while controlling the operation of each component of the automatic analyzer 1 based on the analysis command input from the input unit 26 such as a keyboard, as well as analysis results and warning information. Various information based on the display command input from the input unit 26 is displayed on the display unit 27 such as a display panel. At this time, the control unit 25 determines whether the reaction vessel 6 is to be normally cleaned or specially cleaned based on the analysis information input from the host computer or the analysis command input from the input unit 26, and the cuvette at the time of cleaning is determined. The conveyance direction of the reaction vessel 6 is determined as to whether the upper stage side of the wheel 5 is conveyed or the lower stage side is conveyed.

  The automatic analyzer 1 configured as described above operates under the control of the control unit 25, and is applied to the plurality of reaction vessels 6 arranged in the upper stage conveyed along the circumferential direction by the rotating cuvette wheel 5. After the first reagent is dispensed by the first reagent dispensing device 7, the sample is sequentially dispensed from the plurality of sample containers 11 b by the sample dispensing device 12. The reaction container 6 into which the specimens are sequentially dispensed is agitated by the agitation unit 13, and then the second reagent is dispensed by the second reagent dispensing device 9.

  In this way, the reaction container 6 into which the reagent and the sample are dispensed is sequentially stirred by the stirring unit 13 each time the cuvette wheel 5 is stopped, and the reagent and the sample are reacted, and the cuvette wheel 5 is rotated again. Passes through the photometric unit 14. At this time, the reaction liquid in which the reagent in the reaction container 6 has reacted with the sample is measured by the photometry unit 14 and the component concentration and the like are analyzed by the control unit 25. Then, after the photometry of the reaction liquid is completed, the reaction container 6 is transferred to the washing unit 15 and washed, and then used again for analyzing the specimen.

  At this time, the reaction vessel 6 for analyzing genetic test items with high analytical sensitivity needs to be specially cleaned to a much cleaner state than the reaction vessel 6 for analyzing biochemical test items. In this case, the automatic analyzer 1 operates under the control of the control unit 25, and the reaction vessel 6A to be specially cleaned becomes the detergent nozzle pair 15A of the cleaning unit 15 by stopping the rotation of the cuvette wheel 5 as shown in FIG. When the detergent nozzle pair 15A sucks the reaction liquid from the reaction vessel 6A, the diluted detergent Dt is dispensed into the reaction vessel 6A to be specially cleaned.

  Here, as described above, the cuvette wheel 5 rotates, for example, clockwise (1 turn-1 reaction vessel) / 4 in one cycle and counterclockwise (1 turn-1 reaction vessel) in four cycles. To do. For this reason, the positions of the reaction vessel 6A to be specially cleaned and the cleaning unit 15, the cap attaching unit 16 and the cap removing portion 20 with the rotation of the cuvette wheel 5 are complicated in time. In addition, FIGS. 5 to 9 described below are illustrated in a simplified manner ignoring these positional relationships for easy understanding of the special cleaning process.

  Next, when the reaction container 6A into which the diluted detergent Dt has been dispensed stops at the position of the cap adherent 16 due to the rotation of the cuvette wheel 5 being stopped, the automatic analyzer 1 can remove the cap adherent as shown in FIG. 16 puts the sealing cap C on the reaction vessel 6A. Thereby, in the reaction vessel 6A, the diluted detergent Dt is sealed by the sealing cap C.

  Next, in the automatic analyzer 1, the lower stage moving replacement unit 17 rotates the reaction container 6 as a set together with the support plate P in the vertical direction, and a special cleaning object covered with a sealing cap C as shown in FIG. 6. The reaction vessel 6A is replaced with the lower reaction vessel 6. As a result, the reaction container 6A to be specially cleaned is moved from the upper stage side to the lower stage side, and is transported on a transport path for special cleaning that is different from the transport path of the reaction container 6 to be subjected to normal cleaning. At this time, the reaction vessel 6A is turned upside down by moving to the lower stage, but since it is sealed by the sealing cap C, the diluted detergent Dt does not leak out.

  Then, the reaction vessel 6 </ b> A stops at the position of the upper stage moving replacement unit 21 as shown in FIG. 7 by the rotation of the cuvette wheel 5. Then, in the automatic analyzer 1, as shown in FIG. 8, the upper stage moving replacement unit 21 replaces the reaction container 6 </ b> A with the upper reaction container 6. Thereby, the reaction vessel 6A to be specially cleaned is moved from the lower stage to the upper stage and returned to the transport path of the reaction container 6 to be normally cleaned.

  Next, when the reaction vessel 6A to be specially cleaned is stopped at the position of the cap removal portion 20, the cap removal portion 20 removes the sealing cap C from the reaction vessel 6A as shown in FIG. As a result, the reaction vessel 6A is released from the sealing of the diluted detergent Dt by the sealing cap C, and is subsequently normally washed with washing water in the washing unit 15. The reaction vessel 6A that has been normally cleaned in this way is used again for measurement.

  Accordingly, the reaction container 6A into which the diluted detergent Dt has been dispensed is specially washed with the diluted detergent Dt while being transported on the lower side of the cuvette wheel 5, so that genetic analysis items with high analytical sensitivity are used for analysis. There are no analytical problems. The reaction vessel 6A is transported to the lower side of the cuvette wheel 5 during special cleaning. For this reason, the automatic analyzer 1 has the advantage that the upper stage side of the cuvette wheel 5 can be used for analysis of biochemical test items with low analytical sensitivity even during the special cleaning of the reaction vessel 6A. Have.

  As described above, the automatic analyzer 1 includes a plurality of reaction vessels 6 arranged on the cuvette wheel 5 in two upper and lower stages, a cap attaching part 16 for special cleaning of the reaction container 6, a lower stage moving replacement part 17, a cap removal unit. An external 20 and an upper stage moving replacement unit 21 are provided. Accordingly, the automatic analyzer 1 performs the analysis process on the upper side of the cuvette wheel 5 and cleans the reaction vessel 6 used for the inspection item having a lower analysis sensitivity, while changing the inspection item having a higher analysis sensitivity on the lower side of the cuvette wheel 5. The special cleaning of the reaction vessel 6 to be used can be performed in parallel. For this reason, the automatic analyzer 1 can analyze the sample without reducing the throughput while avoiding contamination.

  As shown in FIG. 10, the reaction vessel 6 is supported between two support plates P having a central axis A so that the respective openings 6a are directed upward and the upper part is pivotable. It may be configured to be attached to the cuvette wheel 5 via A. If comprised in this way, even if it rotates the support plate P in order to replace the two reaction containers 6 to the upper side or the lower side of the cuvette wheel 5, the opening 6a always faces upward. For this reason, the automatic analyzer 1 does not require the cap attaching part 16 and the cap removing part 20.

  Further, as shown in FIG. 11, the automatic analyzer 1 arranges the cleaning unit 15 on the upper side and the lower side of the cuvette wheel 5, and the upper cleaning unit 15 performs normal cleaning that discharges and sucks cleaning liquid or cleaning water. At the same time, the lower cleaning section 15 may perform cleaning by spraying a cleaning liquid or cleaning water onto the reaction vessel 6. In this case, the discharge nozzle 15a and the suction nozzle 15b of the upper cleaning unit 15 are used for cleaning the reaction vessel 6 used for the inspection item having a low analysis sensitivity, and the discharge nozzle 15a of the lower cleaning unit 15 is used for the analysis sensitivity. Used for cleaning the reaction vessel 6 used for high inspection items. If it does in this way, automatic analyzer 1 can separate washing part 15 of reaction container 6 according to the level of analysis sensitivity, and is preferred when avoiding contamination.

  Further, during the special cleaning, the reaction vessel 6 is cleaned with the diluted detergent Dt, but may be immersed and cleaned with cleaning water.

It is a schematic block diagram which shows the automatic analyzer of this invention. It is sectional drawing which cut | disconnected the cuvette wheel of the analyzer of FIG. 1 along the circumferential direction in the part of the washing | cleaning part. It is a perspective view which shows schematic structure of a cap adherence part and a lower stage movement replacement part. It is sectional drawing explaining the reaction container washing | cleaning method of the analyzer of this invention which dispensed dilution detergent to the reaction container used as the object of special washing | cleaning. It is sectional drawing explaining the reaction container washing | cleaning method of the analyzer of this invention which covered the sealing cap on the reaction container shown in FIG. It is sectional drawing explaining the reaction container washing | cleaning method of the analyzer of this invention which replaced the reaction container shown in FIG. 5 with the lower reaction container. It is sectional drawing explaining the reaction container washing | cleaning method of the analyzer of this invention which the reaction container shown in FIG. 6 stopped in the position of the upper stage movement exchange part. It is sectional drawing explaining the reaction container washing | cleaning method of the analyzer of this invention which replaced the reaction container shown in FIG. 7 with the upper reaction container. It is sectional drawing explaining the reaction container washing | cleaning method of the analyzer of this invention which removed the sealing cap from the reaction container shown in FIG. It is a perspective view which shows the other support aspect of the reaction container arrange | positioned at 2 steps | paragraphs on the cuvette wheel. It is sectional drawing corresponding to FIG. 2 which shows the modification which arrange | positions a washing | cleaning part on the upper side and lower side of a cuvette wheel.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Automatic analyzer 2 1st reagent table 3 2nd reagent table 5 cuvette wheel 6 Reaction container 7 1st reagent dispensing apparatus 8 Washing tank 9 2nd reagent dispensing apparatus 10 Washing tank 11 Sample container transfer part 12 Sample dispensing apparatus DESCRIPTION OF SYMBOLS 13 Stirring part 14 Photometry part 15 Washing part 16 Cap adherence part 16a Chuck apparatus 16b Arm member 16c Lifting apparatus 17 Lower stage movement replacement part 18 Actuator 19 Lifting apparatus 19a Post 19b Telescopic arm 20 Cap take-off part 20a Chuck apparatus 20b Arm member 20c Lifting Device 21 Upper stage moving replacement unit 22 Actuator 23 Lifting device 25 Control unit 26 Input unit 27 Display unit A Center axis C Sealing cap Dt Diluted detergent P Support plate

Claims (6)

An analyzer comprising a cleaning device for reacting a liquid sample containing a specimen and a reagent in a plurality of reaction vessels held on a cuvette wheel and washing the reaction vessel after analyzing the reaction solution,
The plurality of reaction vessels are arranged in two upper and lower stages on the cuvette wheel,
An analyzer comprising: replacement means for rotating the upper and lower two-stage reaction vessels as a set and replacing them in a vertical direction at least at two locations near the cuvette wheel. Deposition means for covering the upper reaction vessel with a lid;
Removing means for removing the covered lid from the reaction vessel;
The analyzer according to claim 1, further comprising:   3. The two upper and lower two-stage reaction vessels are fixed between two support plates rotating around a central axis with their respective openings facing upward and downward. The analyzer described in 1.   The two upper and lower two-stage reaction vessels are supported between two support plates rotating around a central axis so that the respective openings can swing upward. Or the analyzer of 2.   The analyzer according to any one of claims 1 to 3, wherein the cleaning devices are arranged on both upper and lower sides of the upper reaction vessel side and the lower reaction vessel side of the cuvette wheel. A reaction vessel cleaning method of an analyzer for reacting a sample and a reagent in a reaction vessel, analyzing the components of the sample by optically measuring a reaction solution, and washing the reaction vessel after completion of photometry,
A normal washing step of washing the reaction vessel;
A special cleaning step of transporting along a transport path different from the transport path of the reaction container for analyzing the sample, and specially cleaning the reaction container;
A method for washing a reaction vessel of an analyzer, comprising:

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