JP2018135352A5 - - Google Patents

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JP2018135352A5
JP2018135352A5 JP2018073109A JP2018073109A JP2018135352A5 JP 2018135352 A5 JP2018135352 A5 JP 2018135352A5 JP 2018073109 A JP2018073109 A JP 2018073109A JP 2018073109 A JP2018073109 A JP 2018073109A JP 2018135352 A5 JP2018135352 A5 JP 2018135352A5
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Japan
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JP2018073109A
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Japanese (ja)
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JP2018135352A (ja
JP6810717B2 (ja
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JP2018073109A 2012-08-01 2018-04-05 プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置 Active JP6810717B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261678208P 2012-08-01 2012-08-01
US61/678,208 2012-08-01
US201361750458P 2013-01-09 2013-01-09
US61/750,458 2013-01-09

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2015525509A Division JP6746313B2 (ja) 2012-08-01 2013-07-30 プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置

Publications (3)

Publication Number Publication Date
JP2018135352A JP2018135352A (ja) 2018-08-30
JP2018135352A5 true JP2018135352A5 (https=) 2018-10-11
JP6810717B2 JP6810717B2 (ja) 2021-01-06

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ID=50028652

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JP2015525509A Active JP6746313B2 (ja) 2012-08-01 2013-07-30 プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置
JP2018073109A Active JP6810717B2 (ja) 2012-08-01 2018-04-05 プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2015525509A Active JP6746313B2 (ja) 2012-08-01 2013-07-30 プロスタサイクリン処理された内皮前駆細胞による肺動脈性高血圧症の処置

Country Status (9)

Country Link
US (4) US10016463B2 (https=)
EP (2) EP2879684B1 (https=)
JP (2) JP6746313B2 (https=)
KR (1) KR102143961B1 (https=)
CN (1) CN104936603A (https=)
CA (1) CA2880811C (https=)
ES (2) ES2869701T3 (https=)
IN (1) IN2015DN00976A (https=)
WO (1) WO2014022376A2 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2880808C (en) 2012-08-01 2023-01-24 United Therapeutics Corporation Treatment of pulmonary arterial hypertension with mesenchymal stem cells
ES2869701T3 (es) * 2012-08-01 2021-10-25 United Therapeutics Corp Tratamiento de hipertensión arterial pulmonar con células progenitoras endoteliales tratadas con prostaciclina
JP6431850B2 (ja) 2013-01-09 2018-11-28 ユナイテッド セラピューティクス コーポレイション プロスタサイクリンおよび間葉系幹細胞による脈管障害の処置
LT3060041T (lt) 2013-10-25 2021-03-25 Insmed Incorporated Prostaciklino junginiai
US20170049822A1 (en) * 2014-04-23 2017-02-23 Texas Heart Institute Methods of enhancing stem cell engraftment
JP6866043B2 (ja) 2014-11-18 2021-04-28 インスメッド インコーポレイテッド トレプロスチニルプロドラッグおよびトレプロスチニル誘導体プロドラッグの製造方法
US10344023B2 (en) 2014-12-23 2019-07-09 Proteostasis Therapeutics, Inc. Derivatives of 3-heteroarylisoxazol-5-carboxylic amide useful for the treatment of inter alia cystic fibrosis
MA43775A (fr) 2016-04-07 2021-05-05 Proteostasis Therapeutics Inc Analogues du ivacaftor conentant des atomes de silicium
ES2927406T3 (es) * 2016-10-24 2022-11-04 United Therapeutics Corp Potenciación de las propiedades inmunomoduladoras de las MSC mediante treprostinil
US20190290597A1 (en) * 2016-12-05 2019-09-26 Corsair Pharma, Inc. Dermal and transdermal administration of treprostinil and salts thereof
US10883084B2 (en) 2018-10-05 2021-01-05 Xenotherapeutics, Inc. Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same
KR20210089659A (ko) 2018-10-05 2021-07-16 제노세라퓨틱스, 인코포레이티드 이종이식 생성물 및 방법
JP7455144B2 (ja) 2019-04-29 2024-03-25 インスメッド インコーポレイテッド トレプロスチニルプロドラッグの乾燥粉末組成物およびその使用方法
CA3147263A1 (en) * 2019-07-15 2021-01-21 Yale University Methods and compositions for treating pulmonary arterial hypertension
KR20220054359A (ko) * 2019-08-28 2022-05-02 아스텔라스 인스티튜트 포 리제너러티브 메디슨 혈관 질병을 치료하는 방법

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3089815A (en) 1951-10-11 1963-05-14 Lieb Hans Injectable pharmaceutical preparation, and a method of making same
US4352883A (en) 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4353888A (en) 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US5130144B1 (en) 1984-02-06 1995-08-15 Univ Johns Hopkins Human stem cells and monoclonal antibodies
US4965204A (en) 1984-02-06 1990-10-23 The Johns Hopkins University Human stem cells and monoclonal antibodies
US4714680B1 (en) 1984-02-06 1995-06-27 Univ Johns Hopkins Human stem cells
US5026365A (en) 1987-04-29 1991-06-25 The University Of Massachusetts Method and apparatus for therapeutically treating immunological disorders and disease states
US4983393A (en) 1987-07-21 1991-01-08 Maximed Corporation Intra-vaginal device and method for sustained drug release
ATE81724T1 (de) 1987-11-09 1992-11-15 Becton Dickinson Co Verfahren zur analyse haematopoietischer zellen in einer probe.
US5283187A (en) 1987-11-17 1994-02-01 Brown University Research Foundation Cell culture-containing tubular capsule produced by co-extrusion
US5158881A (en) 1987-11-17 1992-10-27 Brown University Research Foundation Method and system for encapsulating cells in a tubular extrudate in separate cell compartments
US5071741A (en) 1988-04-18 1991-12-10 Cryolife, Inc. Cryoprotective agent and its use in cryopreservation of cellular matter
DE3829766A1 (de) 1988-09-01 1990-03-22 Akzo Gmbh Verfahren zur herstellung von membranen
DE3829752A1 (de) 1988-09-01 1990-03-22 Akzo Gmbh Integrale asymmetrische polyaethersulfonmembran, verfahren zur herstellung und verwendung zur ultrafiltration und mikrofiltration
US5084350A (en) 1990-02-16 1992-01-28 The Royal Institution For The Advance Of Learning (Mcgill University) Method for encapsulating biologically active material including cells
US5061620A (en) 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US5283058A (en) 1990-08-30 1994-02-01 The General Hospital Corporation Methods for inhibiting rejection of transplanted tissue
US5173414A (en) 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
US5811094A (en) 1990-11-16 1998-09-22 Osiris Therapeutics, Inc. Connective tissue regeneration using human mesenchymal stem cell preparations
CA2109085C (en) 1991-04-25 2003-03-11 Keith E. Dionne Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products
AU672775B2 (en) 1992-01-21 1996-10-17 Cobe Laboratories Inc. Method of freezing cells and cell-like materials
US5834256A (en) 1993-06-11 1998-11-10 Cell Genesys, Inc. Method for production of high titer virus and high efficiency retroviral mediated transduction of mammalian cells
ATE218893T1 (de) 1993-08-12 2002-06-15 Neurotech Sa Biokompatible immunoisolatorische kapseln, die genetisch veränderte zellen enthalten
US5518878A (en) 1993-09-15 1996-05-21 Organogenesis Inc. Cryopreservation of cultured skin or cornea equivalents with agitation
US5693531A (en) 1993-11-24 1997-12-02 The United States Of America As Represented By The Department Of Health And Human Services Vector systems for the generation of adeno-associated virus particles
DE69530914T2 (de) 1994-02-17 2004-03-11 New York Blood Center, Inc. Biologische bioadhäsive präparate, die fibrinkleber und liposomen enthalten, verfahren für ihre herstellung und verwendung
US7252989B1 (en) 1994-04-04 2007-08-07 Board Of Regents, The University Of Texas System Adenovirus supervector system
US5580714A (en) 1995-03-08 1996-12-03 Celox Laboratories, Inc. Cryopreservation solution
US5629145A (en) 1995-03-24 1997-05-13 Organ, Inc. Cryopreservation of cell suspensions
US5643192A (en) 1995-04-06 1997-07-01 Hamilton Civic Hospitals Research Development, Inc. Autologous fibrin glue and methods for its preparation and use
US5910434A (en) 1995-12-15 1999-06-08 Systemix, Inc. Method for obtaining retroviral packaging cell lines producing high transducing efficiency retroviral supernatant
WO1997021824A2 (en) 1995-12-15 1997-06-19 Systemix, Inc. Method for obtaining retroviral vector supernatant having high transduction efficiency
AU4659697A (en) 1996-10-03 1998-04-24 Regents Of The University Of California, The Cryopreservation of human adult and fetal pancreatic cells and human platelets
CA2296704C (en) 1997-07-14 2010-10-19 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
US9585916B2 (en) 1999-03-26 2017-03-07 Northern Therapeutics Inc. Cell based therapy for the pulmonary system
US20030118567A1 (en) 1999-03-26 2003-06-26 Stewart Duncan John Cell-based therapy for the pulmonary system
US6197294B1 (en) 1998-10-26 2001-03-06 Neurotech S.A. Cell surface molecule-induced macrophage activation
AU2003901668A0 (en) 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
AUPQ147799A0 (en) 1999-07-07 1999-07-29 Medvet Science Pty. Ltd. Mesenchymal precursor cell
US9320829B2 (en) 2000-03-15 2016-04-26 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
JP2004513676A (ja) 2000-06-22 2004-05-13 オースティン,サム,エル 生体接着剤組成物及びその製造と使用
WO2004050180A2 (en) 2002-11-30 2004-06-17 Cardiac Pacemakers, Inc. Method and apparatus for cell and electrical therapy of living tissue
CN1917866B (zh) 2003-12-16 2010-12-15 联合治疗公司 曲前列环素或它的衍生物,或其药学上可接受的盐在制备治疗和预防缺血性损害的药物中的用途
CA2866468C (en) 2004-09-24 2019-09-03 Mesoblast, Inc. Generating multipotential expanded mesenchymal precursor cell progeny (memp) from mesenchymal progenitor cells (mpc) and stimulation factor
EP1940445B1 (en) 2005-08-19 2011-02-02 Duke University Stem cell derived paracrine factor h12 for use in reducing cell death or enhancing tissue repair
US20070065414A1 (en) 2005-09-16 2007-03-22 Boston Scientific Scimed, Inc. Enhanced delivery of cells
US8652201B2 (en) * 2006-04-26 2014-02-18 The Cleveland Clinic Foundation Apparatus and method for treating cardiovascular diseases
WO2007124594A1 (en) 2006-04-27 2007-11-08 Cell Therapy Technologies, Inc. Et Al. Stem cells for treating lung diseases
US20100040584A1 (en) 2006-12-19 2010-02-18 Children's Medical Center Corporation Methods for promoting neovascularization
NZ612888A (en) 2007-02-12 2015-02-27 Anthrogenesis Corp Treatment of inflammatory diseases using placental stem cells
JP2011015609A (ja) * 2007-10-30 2011-01-27 Asahikawa Medical College 内皮前駆細胞(epc)の増殖・分化誘導方法
CN102014934B (zh) 2008-02-22 2014-08-20 新加坡科技研究局 间充质干细胞颗粒
EP2608797B1 (en) 2010-08-27 2015-09-23 University of Miami Bone marrow derived cd271 precursor cells for cardiac repair
PT2760994T (pt) 2011-09-30 2017-08-24 Bluebird Bio Inc Compostos para melhor transdução viral
ES2869701T3 (es) * 2012-08-01 2021-10-25 United Therapeutics Corp Tratamiento de hipertensión arterial pulmonar con células progenitoras endoteliales tratadas con prostaciclina
CA2880808C (en) 2012-08-01 2023-01-24 United Therapeutics Corporation Treatment of pulmonary arterial hypertension with mesenchymal stem cells
JP6431850B2 (ja) * 2013-01-09 2018-11-28 ユナイテッド セラピューティクス コーポレイション プロスタサイクリンおよび間葉系幹細胞による脈管障害の処置
US9924630B2 (en) 2014-11-14 2018-03-27 Luitauras Kairys Device for connecting two rakes
ES2927406T3 (es) 2016-10-24 2022-11-04 United Therapeutics Corp Potenciación de las propiedades inmunomoduladoras de las MSC mediante treprostinil

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