JP2017537163A5 - - Google Patents
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- Publication number
- JP2017537163A5 JP2017537163A5 JP2017548347A JP2017548347A JP2017537163A5 JP 2017537163 A5 JP2017537163 A5 JP 2017537163A5 JP 2017548347 A JP2017548347 A JP 2017548347A JP 2017548347 A JP2017548347 A JP 2017548347A JP 2017537163 A5 JP2017537163 A5 JP 2017537163A5
- Authority
- JP
- Japan
- Prior art keywords
- tanshinone
- medicament according
- chronic wound
- dihydrotanshinone
- wound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- AIGAZQPHXLWMOJ-UHFFFAOYSA-N Tanshinone I Chemical class C1=CC2=C(C)C=CC=C2C(C(=O)C2=O)=C1C1=C2C(C)=CO1 AIGAZQPHXLWMOJ-UHFFFAOYSA-N 0.000 claims description 36
- 206010052428 Wound Diseases 0.000 claims description 18
- 208000027418 Wounds and injury Diseases 0.000 claims description 18
- 239000000419 plant extract Substances 0.000 claims description 14
- 239000003814 drug Substances 0.000 claims description 12
- 241001072909 Salvia Species 0.000 claims description 11
- 235000017276 Salvia Nutrition 0.000 claims description 11
- 230000001684 chronic effect Effects 0.000 claims description 11
- HARGZZNYNSYSGJ-UHFFFAOYSA-N 1,2 dihydrotanshinquinone Natural products C1=CC2=C(C)C=CC=C2C(C(=O)C2=O)=C1C1=C2C(C)CO1 HARGZZNYNSYSGJ-UHFFFAOYSA-N 0.000 claims description 8
- HARGZZNYNSYSGJ-JTQLQIEISA-N Dihydrotanshinone I Chemical compound C1=CC2=C(C)C=CC=C2C(C(=O)C2=O)=C1C1=C2[C@@H](C)CO1 HARGZZNYNSYSGJ-JTQLQIEISA-N 0.000 claims description 8
- 239000002537 cosmetic Substances 0.000 claims description 8
- KXNYCALHDXGJSF-UHFFFAOYSA-N dihydroisotanshinone I Natural products CC1=CC=CC2=C(C(C=3OCC(C=3C3=O)C)=O)C3=CC=C21 KXNYCALHDXGJSF-UHFFFAOYSA-N 0.000 claims description 7
- 208000014311 Cushing syndrome Diseases 0.000 claims description 5
- 102100024332 Cytochrome P450 11B1, mitochondrial Human genes 0.000 claims description 5
- 108010049356 Steroid 11-beta-Hydroxylase Proteins 0.000 claims description 5
- 201000009395 primary hyperaldosteronism Diseases 0.000 claims description 5
- GVKKJJOMQCNPGB-JTQLQIEISA-N Cryptotanshinone Chemical compound O=C1C(=O)C2=C3CCCC(C)(C)C3=CC=C2C2=C1[C@@H](C)CO2 GVKKJJOMQCNPGB-JTQLQIEISA-N 0.000 claims description 4
- GVKKJJOMQCNPGB-UHFFFAOYSA-N Cryptotanshinone Natural products O=C1C(=O)C2=C3CCCC(C)(C)C3=CC=C2C2=C1C(C)CO2 GVKKJJOMQCNPGB-UHFFFAOYSA-N 0.000 claims description 4
- 229930183118 Tanshinone Natural products 0.000 claims description 3
- 230000002401 inhibitory effect Effects 0.000 claims description 3
- HYXITZLLTYIPOF-UHFFFAOYSA-N Tanshinone II Natural products O=C1C(=O)C2=C3CCCC(C)(C)C3=CC=C2C2=C1C(C)=CO2 HYXITZLLTYIPOF-UHFFFAOYSA-N 0.000 claims description 2
- 208000025865 Ulcer Diseases 0.000 claims description 2
- 239000012876 carrier material Substances 0.000 claims description 2
- 230000006835 compression Effects 0.000 claims description 2
- 238000007906 compression Methods 0.000 claims description 2
- 206010012601 diabetes mellitus Diseases 0.000 claims description 2
- 239000000284 extract Substances 0.000 claims description 2
- 230000007774 longterm Effects 0.000 claims description 2
- 239000002324 mouth wash Substances 0.000 claims description 2
- 229940051866 mouthwash Drugs 0.000 claims description 2
- 230000003239 periodontal effect Effects 0.000 claims description 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 2
- 230000005855 radiation Effects 0.000 claims description 2
- AZEZEAABTDXEHR-UHFFFAOYSA-M sodium;1,6,6-trimethyl-10,11-dioxo-8,9-dihydro-7h-naphtho[1,2-g][1]benzofuran-2-sulfonate Chemical compound [Na+].C12=CC=C(C(CCC3)(C)C)C3=C2C(=O)C(=O)C2=C1OC(S([O-])(=O)=O)=C2C AZEZEAABTDXEHR-UHFFFAOYSA-M 0.000 claims description 2
- -1 tanshinone compound Chemical class 0.000 claims description 2
- 239000000606 toothpaste Substances 0.000 claims description 2
- 229940034610 toothpaste Drugs 0.000 claims description 2
- 231100000397 ulcer Toxicity 0.000 claims description 2
- 210000002615 epidermis Anatomy 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1421479.5A GB201421479D0 (en) | 2014-12-03 | 2014-12-03 | A plant extract and compounds for use in wound healing |
| GB1421479.5 | 2014-12-03 | ||
| PCT/GB2015/000312 WO2016087810A1 (en) | 2014-12-03 | 2015-11-30 | A plant extract and compounds for use in wound healing |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017537163A JP2017537163A (ja) | 2017-12-14 |
| JP2017537163A5 true JP2017537163A5 (enExample) | 2019-01-17 |
| JP6829691B2 JP6829691B2 (ja) | 2021-02-10 |
Family
ID=52349874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017548347A Expired - Fee Related JP6829691B2 (ja) | 2014-12-03 | 2015-11-30 | 創傷治癒に使用するための植物抽出物及び化合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20180228858A1 (enExample) |
| EP (1) | EP3226879A1 (enExample) |
| JP (1) | JP6829691B2 (enExample) |
| CN (1) | CN107135645A (enExample) |
| GB (2) | GB201421479D0 (enExample) |
| WO (1) | WO2016087810A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102687221B1 (ko) * | 2016-12-05 | 2024-07-22 | 주식회사 엘지생활건강 | 디하이드로탄시논 ⅰ을 포함하는 구강질환 예방 또는 치료용 조성물 |
| CN110251716B (zh) * | 2019-04-22 | 2020-12-18 | 张贤慧 | 一种伤口护理用凝胶敷料及其制备方法 |
| US20210393585A1 (en) * | 2020-06-19 | 2021-12-23 | Tzu Chi University | Method for preventing and/or treating a stress-induced disease |
| TWI750705B (zh) * | 2020-06-19 | 2021-12-21 | 慈濟學校財團法人慈濟大學 | 預防及/或治療壓力誘發疾病之方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59163319A (ja) * | 1983-03-07 | 1984-09-14 | Sawai Seiyaku Kk | 抗真菌剤 |
| JPH0830077B2 (ja) * | 1987-04-24 | 1996-03-27 | 晟 八木 | 虚血性疾患治療剤 |
| DE4303823C2 (de) * | 1993-02-10 | 1997-08-07 | Isernhagen Heilmittelbetr Gmbh | Verwendung eines Extraktes aus Blüten von Salvia officinalis bei der Bekämpfung von Durchblutungsstörungen |
| KR100861186B1 (ko) * | 2001-03-26 | 2008-09-30 | 주식회사 엘지생활건강 | 크립토탄시논을 함유하는 여드름 예방 및 치료용 화장료 |
| AU2004308874B2 (en) * | 2003-12-30 | 2011-01-27 | Kt & G Co., Ltd | Obesity and metabolic syndrome treatment with tanshinone derivatives which increase metabolic activity |
| CA2595564C (en) * | 2005-02-16 | 2015-03-31 | Md Bioalpha Co., Ltd. | Use of .beta.-lapachone and related naphthoquinones in the treatment of amp-activated protein kinase (ampk) mediated disorders |
| KR100725839B1 (ko) * | 2005-10-06 | 2007-12-11 | 일성신약주식회사 | 단삼으로부터 분리된 탄시논류의 화합물을 함유하는인지기능 장애의 예방 및 치료용 조성물 |
| GB2453807A (en) * | 2007-10-15 | 2009-04-22 | Botan Century | Purified tanshinone extracts from Salvia spp and their antibacterial effects |
| JP2010106001A (ja) * | 2008-10-31 | 2010-05-13 | Theravalues Corp | Ｐｐａｒ活性化剤 |
| CN101642486B (zh) * | 2009-08-28 | 2011-09-21 | 湖南省中医药研究院 | 一种促进创伤愈合的中药组合物及其制备方法 |
| CN102579650B (zh) * | 2011-03-10 | 2014-02-26 | 成都中医药大学 | 一种预防或/和治疗压疮的药物组合物及其制备方法和用途 |
| CN102727581B (zh) * | 2011-04-11 | 2016-02-10 | 苏州瑞美科生物技术有限公司 | 一种对伤口具有修复作用的药物组合物 |
| CN103356844B (zh) * | 2012-03-28 | 2015-12-16 | 苏州瑞美科生物技术有限公司 | 一种低聚壳聚糖复方制剂及其在制备治疗皮肤疾病的药物中应用 |
| CN102824599B (zh) * | 2012-08-07 | 2013-12-25 | 孟庆德 | 一种治疗糖尿病引起的各种皮肤溃烂的中药酊剂 |
| CN102988370A (zh) * | 2012-11-23 | 2013-03-27 | 广东省中医院 | 丹参酮i在制备治疗银屑病药物中的应用 |
| CN103830175A (zh) * | 2012-11-26 | 2014-06-04 | 青岛百草汇中草药研究所 | 含有丹参酮的乳剂及其制备方法 |
| CN103040956A (zh) * | 2013-01-18 | 2013-04-17 | 江其生 | 一种能预防和治疗皮肤放射损伤的中药组合物 |
| CN103230493B (zh) * | 2013-04-15 | 2015-04-22 | 杨少辉 | 一种治疗创口不愈的中药组合物 |
| CN103705616A (zh) * | 2014-01-02 | 2014-04-09 | 魏春战 | 一种祛腐生肌膏的配方 |
-
2014
- 2014-12-03 GB GBGB1421479.5A patent/GB201421479D0/en not_active Ceased
-
2015
- 2015-11-30 WO PCT/GB2015/000312 patent/WO2016087810A1/en not_active Ceased
- 2015-11-30 CN CN201580073703.XA patent/CN107135645A/zh active Pending
- 2015-11-30 US US15/533,009 patent/US20180228858A1/en not_active Abandoned
- 2015-11-30 EP EP15807964.0A patent/EP3226879A1/en not_active Withdrawn
- 2015-11-30 JP JP2017548347A patent/JP6829691B2/ja not_active Expired - Fee Related
- 2015-12-01 GB GB1521166.7A patent/GB2538580B/en not_active Expired - Fee Related
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