JP2017537126A5 - - Google Patents
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- JP2017537126A5 JP2017537126A5 JP2017530728A JP2017530728A JP2017537126A5 JP 2017537126 A5 JP2017537126 A5 JP 2017537126A5 JP 2017530728 A JP2017530728 A JP 2017530728A JP 2017530728 A JP2017530728 A JP 2017530728A JP 2017537126 A5 JP2017537126 A5 JP 2017537126A5
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- JP
- Japan
- Prior art keywords
- pharmaceutical composition
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- small cell
- lung cancer
- cell lung
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410749394.0 | 2014-12-09 | ||
| CN201410749394 | 2014-12-09 | ||
| PCT/CN2015/096777 WO2016091168A1 (zh) | 2014-12-09 | 2015-12-09 | 抗非小细胞肺癌的喹啉衍生物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017537126A JP2017537126A (ja) | 2017-12-14 |
| JP2017537126A5 true JP2017537126A5 (cg-RX-API-DMAC7.html) | 2020-03-05 |
| JP6865684B2 JP6865684B2 (ja) | 2021-04-28 |
Family
ID=56106719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017530728A Active JP6865684B2 (ja) | 2014-12-09 | 2015-12-09 | 非小細胞肺癌に対するキノリン誘導体 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10307412B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3231797B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6865684B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN107001326B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2015360095B2 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2793286T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016091168A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105311030B (zh) * | 2014-06-06 | 2020-03-24 | 正大天晴药业集团股份有限公司 | 用于抗肿瘤的螺取代化合物 |
| CN105311029A (zh) | 2014-06-06 | 2016-02-10 | 正大天晴药业集团股份有限公司 | 抗肿瘤活性的喹啉衍生物 |
| US10307412B2 (en) | 2014-12-09 | 2019-06-04 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Quinoline derivative against non-small cell lung cancer |
| US9751859B2 (en) | 2015-05-04 | 2017-09-05 | Advenchen Pharmaceuticals, LLC | Process for preparing an anti-cancer agent, 1-((4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropanamine, its crystalline form and its salts |
| CN108601773B (zh) | 2015-07-11 | 2025-12-19 | 南京爱德程医药科技有限公司 | 作为pi3k/mtor抑制剂的稠合喹啉化合物 |
| CN107296811B (zh) | 2016-04-15 | 2022-12-30 | 正大天晴药业集团股份有限公司 | 一种用于治疗胃癌的喹啉衍生物 |
| AU2019227391B2 (en) | 2018-03-02 | 2024-06-13 | Advenchen Laboratories Nanjing Ltd. | Crystal of compound as c-Met kinase inhibitor and preparation method therefor and use thereof |
| CN116440134A (zh) * | 2018-05-22 | 2023-07-18 | 正大天晴药业集团股份有限公司 | 用于治疗非小细胞肺癌的喹啉衍生物 |
| CN112566661B (zh) * | 2018-07-18 | 2024-02-02 | 正大天晴药业集团股份有限公司 | 喹啉衍生物与抗体的药物组合 |
| CN117085016A (zh) * | 2018-09-18 | 2023-11-21 | 正大天晴药业集团股份有限公司 | 用于治疗小细胞肺癌的喹啉衍生物 |
| WO2020057536A1 (zh) * | 2018-09-18 | 2020-03-26 | 正大天晴药业集团股份有限公司 | 用于治疗脑肿瘤的喹啉衍生物 |
| JP2022524761A (ja) * | 2019-03-07 | 2022-05-10 | アドヴェンチェン ファーマスーティカルズ，エルエルシー | 癌治療のための標準的な化学療法または免疫療法と組み合わせたカテケンチニブ（アンロチニブ）の順次使用 |
| CN113613674B (zh) * | 2019-03-15 | 2024-11-05 | 正大天晴药业集团股份有限公司 | 治疗小细胞肺癌的联用药物组合物 |
| CN112274511B (zh) * | 2019-07-22 | 2024-04-02 | 正大天晴药业集团股份有限公司 | 用于治疗移植物抗宿主病的喹啉衍生物 |
| JP2022550037A (ja) * | 2019-09-25 | 2022-11-30 | デバイオファーム インターナショナル エス．エー． | 局所進行性扁平上皮癌を有する患者の治療のための投与レジメン |
| CN114761010B (zh) * | 2019-11-25 | 2024-04-16 | 正大天晴药业集团股份有限公司 | 喹唑啉衍生物或其盐的联用药物组合物及其用途 |
| CN120154618B (zh) * | 2025-05-15 | 2025-11-18 | 正大天晴药业集团股份有限公司 | 格索雷塞用于治疗肺癌的用途或其药物组合物 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
| AU2008218806B2 (en) | 2007-02-20 | 2011-12-01 | Novartis Ag | Imidazoquinolines as dual lipid kinase and mTOR inhibitors |
| US8148532B2 (en) * | 2007-03-14 | 2012-04-03 | Guoqing Paul Chen | Spiro substituted compounds as angiogenesis inhibitors |
| US8163923B2 (en) | 2007-03-14 | 2012-04-24 | Advenchen Laboratories, Llc | Spiro substituted compounds as angiogenesis inhibitors |
| US20110212053A1 (en) | 2008-06-19 | 2011-09-01 | Dapeng Qian | Phosphatidylinositol 3 kinase inhibitors |
| IT1393351B1 (it) | 2009-03-16 | 2012-04-20 | Eos Ethical Oncology Science Spa In Forma Abbreviata Eos Spa | Procedimento per la preparazione della 6-(7-((1-amminociclopropil)metossi)-6-metossichinolin-4-ilossi)-n-metil-1-naftammide e suoi intermedi di sintesi |
| CN102344438B (zh) * | 2010-08-01 | 2014-02-19 | 正大天晴药业集团股份有限公司 | 喹啉衍生物的结晶及其制备方法 |
| CN103974954B (zh) * | 2011-11-14 | 2016-08-24 | 北京赛林泰医药技术有限公司 | 调节激酶的化合物、含有它们的组合物及其用途 |
| HK1217328A1 (zh) | 2013-01-18 | 2017-01-06 | Advenchen Pharmaceuticals Llc | 製備抗腫瘤劑 6-(7-((1-氨基環丙基)甲氧基)-6-甲氧基喹啉-4-基氧基)-n-甲基-1-萘甲酰胺的方法及其結晶 |
| CN104513229A (zh) * | 2013-09-28 | 2015-04-15 | 正大天晴药业集团股份有限公司 | 喹唑啉衍生物及其制备方法 |
| CN105311029A (zh) | 2014-06-06 | 2016-02-10 | 正大天晴药业集团股份有限公司 | 抗肿瘤活性的喹啉衍生物 |
| CN105311030B (zh) | 2014-06-06 | 2020-03-24 | 正大天晴药业集团股份有限公司 | 用于抗肿瘤的螺取代化合物 |
| KR102426138B1 (ko) | 2014-07-14 | 2022-07-28 | 어드벤첸 라보라토리스 난징 리미티드 | ＰＩ3Ｋ, ｍＴＯＲ 저해제로서 융합된 퀴놀린 화합물 |
| US10307412B2 (en) | 2014-12-09 | 2019-06-04 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Quinoline derivative against non-small cell lung cancer |
| US9751859B2 (en) | 2015-05-04 | 2017-09-05 | Advenchen Pharmaceuticals, LLC | Process for preparing an anti-cancer agent, 1-((4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropanamine, its crystalline form and its salts |
| CN108601773B (zh) | 2015-07-11 | 2025-12-19 | 南京爱德程医药科技有限公司 | 作为pi3k/mtor抑制剂的稠合喹啉化合物 |
| CN107296811B (zh) | 2016-04-15 | 2022-12-30 | 正大天晴药业集团股份有限公司 | 一种用于治疗胃癌的喹啉衍生物 |
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2015
- 2015-12-09 US US15/533,873 patent/US10307412B2/en active Active
- 2015-12-09 AU AU2015360095A patent/AU2015360095B2/en active Active
- 2015-12-09 CN CN201580066275.8A patent/CN107001326B/zh active Active
- 2015-12-09 EP EP15867543.9A patent/EP3231797B1/en active Active
- 2015-12-09 WO PCT/CN2015/096777 patent/WO2016091168A1/zh not_active Ceased
- 2015-12-09 ES ES15867543T patent/ES2793286T3/es active Active
- 2015-12-09 JP JP2017530728A patent/JP6865684B2/ja active Active
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2019
- 2019-04-12 US US16/383,288 patent/US10888559B2/en active Active